Danio rerio

0 known processes

ef1

ETS-related factor1

(Aliases: zef1,fb05d07,wu:fb05d07)

ef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gastrulation GO:0007369 208 0.537
digestive tract morphogenesis GO:0048546 231 0.500
blood vessel morphogenesis GO:0048514 216 0.246
brain development GO:0007420 293 0.181
regulation of nitrogen compound metabolic process GO:0051171 251 0.164
Human Mouse
digestive system development GO:0055123 289 0.160
positive regulation of biological process GO:0048518 253 0.155
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.143
Human Mouse
segmentation GO:0035282 97 0.142
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.134
Human Mouse
regulation of stem cell differentiation GO:2000736 4 0.125
axis specification GO:0009798 43 0.113
cardiac cell fate commitment GO:0060911 1 0.112
digestive tract development GO:0048565 265 0.106
macromolecule biosynthetic process GO:0009059 227 0.105
Human Mouse
tube morphogenesis GO:0035239 349 0.104
sensory system development GO:0048880 76 0.101
biosynthetic process GO:0009058 294 0.101
Human Mouse
muscle cell differentiation GO:0042692 139 0.094
regulation of developmental process GO:0050793 247 0.091
neuron differentiation GO:0030182 353 0.090
locomotion GO:0040011 313 0.085
vasculogenesis GO:0001570 41 0.084
gastrulation with mouth forming second GO:0001702 44 0.084
nuclear transport GO:0051169 4 0.081
protein import into nucleus GO:0006606 3 0.080
phagocytosis GO:0006909 3 0.078
response to stress GO:0006950 263 0.077
nucleobase containing compound biosynthetic process GO:0034654 205 0.076
Human Mouse
regulation of gene expression GO:0010468 265 0.074
Human Mouse
myeloid cell differentiation GO:0030099 86 0.074
negative regulation of stem cell differentiation GO:2000737 2 0.074
negative regulation of biological process GO:0048519 304 0.074
stem cell differentiation GO:0048863 117 0.073
regionalization GO:0003002 274 0.071
generation of neurons GO:0048699 385 0.065
adherens junction organization GO:0034332 4 0.064
establishment of protein localization to organelle GO:0072594 4 0.064
cell motility GO:0048870 244 0.064
cellular nitrogen compound biosynthetic process GO:0044271 218 0.062
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.062
signal transduction GO:0007165 455 0.061
embryonic pattern specification GO:0009880 44 0.061
regulation of response to stimulus GO:0048583 269 0.057
regulation of nucleic acid templated transcription GO:1903506 213 0.056
Human Mouse
immune system process GO:0002376 241 0.054
Mouse
axon development GO:0061564 166 0.053
actin filament based movement GO:0030048 1 0.053
synaptic vesicle transport GO:0048489 1 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.051
Human Mouse
muscle fiber development GO:0048747 52 0.051
single organism localization GO:1902578 225 0.050
organic substance biosynthetic process GO:1901576 289 0.050
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.050
negative regulation of signaling GO:0023057 96 0.049
nucleic acid metabolic process GO:0090304 244 0.049
Human Mouse
single organism nuclear import GO:1902593 3 0.049
rna metabolic process GO:0016070 219 0.048
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.047
Human Mouse
muscle structure development GO:0061061 196 0.047
stem cell maintenance GO:0019827 4 0.047
neuron projection development GO:0031175 180 0.047
larval development GO:0002164 2 0.046
central nervous system development GO:0007417 387 0.046
transport GO:0006810 220 0.044
muscle cell development GO:0055001 115 0.043
regulation of protein targeting GO:1903533 2 0.043
anterior posterior pattern specification GO:0009952 152 0.043
negative regulation of response to stimulus GO:0048585 104 0.042
negative regulation of cell fate specification GO:0009996 11 0.042
aromatic compound biosynthetic process GO:0019438 217 0.042
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.041
Human Mouse
cellular biosynthetic process GO:0044249 286 0.040
Human Mouse
aging GO:0007568 2 0.040
angiogenesis GO:0001525 158 0.040
vasculature development GO:0001944 278 0.040
synaptic vesicle localization GO:0097479 1 0.039
establishment of localization GO:0051234 244 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
Human Mouse
negative regulation of cell fate commitment GO:0010454 13 0.039
embryonic axis specification GO:0000578 12 0.039
cellular macromolecule biosynthetic process GO:0034645 224 0.038
Human Mouse
cardiac conduction GO:0061337 3 0.038
protein localization to plasma membrane GO:0072659 1 0.037
hemopoiesis GO:0030097 183 0.037
single organism organelle organization GO:1902589 199 0.037
positive regulation of macromolecule metabolic process GO:0010604 93 0.036
Human Mouse
striated muscle cell differentiation GO:0051146 129 0.036
transcription dna templated GO:0006351 181 0.036
Human Mouse
regulation of metabolic process GO:0019222 359 0.036
Human Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.035
sprouting angiogenesis GO:0002040 53 0.035
regulation of protein import into nucleus GO:0042306 2 0.035
primitive hemopoiesis GO:0060215 27 0.035
nuclear import GO:0051170 3 0.035
synaptic transmission cholinergic GO:0007271 4 0.035
regulation of cell communication GO:0010646 232 0.035
regulation of muscle contraction GO:0006937 3 0.035
protein complex localization GO:0031503 1 0.034
cell migration GO:0016477 237 0.034
convergent extension involved in gastrulation GO:0060027 71 0.034
positive regulation of cellular process GO:0048522 201 0.034
Human Mouse
positive regulation of transport GO:0051050 2 0.034
heterocycle metabolic process GO:0046483 290 0.034
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.034
Human Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.033
mesoderm development GO:0007498 88 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
regulation of signal transduction GO:0009966 225 0.033
localization of cell GO:0051674 244 0.033
regulation of rna biosynthetic process GO:2001141 213 0.032
Human Mouse
positive regulation of protein polymerization GO:0032273 2 0.032
embryonic hemopoiesis GO:0035162 53 0.032
regulation of cell projection assembly GO:0060491 4 0.032
negative regulation of cell differentiation GO:0045596 46 0.031
protein targeting to nucleus GO:0044744 3 0.031
regulation of rna metabolic process GO:0051252 224 0.031
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.031
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.031
Human Mouse
regulation of cell differentiation GO:0045595 142 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
axonogenesis GO:0007409 152 0.030
protein import GO:0017038 3 0.030
enzyme linked receptor protein signaling pathway GO:0007167 106 0.030
neuroblast fate commitment GO:0014017 1 0.030
negative regulation of protein kinase activity GO:0006469 4 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
mitotic cell cycle GO:0000278 64 0.029
positive regulation of gene expression GO:0010628 71 0.029
Human Mouse
desmosome assembly GO:0002159 2 0.029
embryonic organ development GO:0048568 381 0.029
somatic stem cell maintenance GO:0035019 1 0.029
regulation of cell development GO:0060284 100 0.028
hematopoietic or lymphoid organ development GO:0048534 191 0.028
regulation of reproductive process GO:2000241 4 0.028
regulation of cell maturation GO:1903429 1 0.028
exocytosis GO:0006887 1 0.028
gene expression GO:0010467 252 0.028
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.027
Human Mouse
multicellular organism growth GO:0035264 4 0.027
cellular component movement GO:0006928 335 0.027
morphogenesis of an epithelium GO:0002009 333 0.027
regulation of protein complex assembly GO:0043254 3 0.027
mesenchyme development GO:0060485 127 0.026
neuron projection regeneration GO:0031102 16 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
Human Mouse
single organism transport GO:0044765 206 0.026
protein localization to nucleus GO:0034504 3 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.025
Human Mouse
immune system development GO:0002520 191 0.025
regulation of transcription dna templated GO:0006355 213 0.025
Human Mouse
specification of organ identity GO:0010092 2 0.025
cellular response to lipopolysaccharide GO:0071222 3 0.025
regulation of cell shape GO:0008360 1 0.025
positive regulation of rna metabolic process GO:0051254 59 0.025
Human Mouse
neutrophil mediated immunity GO:0002446 1 0.024
myelin assembly GO:0032288 1 0.024
regulation of neurotransmitter secretion GO:0046928 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.024
blood vessel development GO:0001568 246 0.024
nucleic acid templated transcription GO:0097659 181 0.024
Human Mouse
epithelial cell differentiation GO:0030855 116 0.023
autophagy GO:0006914 4 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
lateral line development GO:0048882 66 0.023
cognition GO:0050890 1 0.023
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.023
maintenance of location GO:0051235 4 0.022
establishment of endothelial barrier GO:0061028 3 0.022
cellular component morphogenesis GO:0032989 336 0.022
regulation of notch signaling pathway GO:0008593 16 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.022
posterior lateral line system development GO:0048915 46 0.022
mesodermal cell differentiation GO:0048333 21 0.022
negative regulation of developmental process GO:0051093 65 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
heart field specification GO:0003128 1 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.022
action potential GO:0001508 19 0.021
regulation of cell fate commitment GO:0010453 22 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
heart morphogenesis GO:0003007 156 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
regulation of embryonic development GO:0045995 47 0.021
maternal determination of anterior posterior axis embryo GO:0008358 4 0.021
meiotic nuclear division GO:0007126 4 0.021
negative regulation of protein localization to nucleus GO:1900181 2 0.021
protein stabilization GO:0050821 2 0.021
regulation of gtp catabolic process GO:0033124 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
negative regulation of intracellular protein transport GO:0090317 3 0.020
regulation of mrna processing GO:0050684 3 0.020
regulation of neurogenesis GO:0050767 87 0.020
actin mediated cell contraction GO:0070252 1 0.020
cardiocyte differentiation GO:0035051 44 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
organelle organization GO:0006996 227 0.020
leukocyte mediated cytotoxicity GO:0001909 1 0.020
epidermis development GO:0008544 48 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
neuron development GO:0048666 262 0.019
notochord development GO:0030903 54 0.019
regulation of cytokine production GO:0001817 3 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
heart development GO:0007507 313 0.019
multicellular organismal signaling GO:0035637 22 0.018
regeneration GO:0031099 91 0.018
cell substrate adhesion GO:0031589 4 0.018
negative regulation of cell communication GO:0010648 96 0.018
convergent extension GO:0060026 118 0.018
neuron projection morphogenesis GO:0048812 161 0.018
anterior posterior axis specification GO:0009948 20 0.018
regulation of signaling GO:0023051 235 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
head development GO:0060322 303 0.017
notochord morphogenesis GO:0048570 17 0.017
stem cell fate determination GO:0048867 1 0.017
positive regulation of reproductive process GO:2000243 2 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
positive regulation of secretion GO:0051047 1 0.017
epiboly GO:0090504 41 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
Human Mouse
regulation of calcium ion transport GO:0051924 2 0.016
single organism membrane fusion GO:0044801 2 0.016
pronephros development GO:0048793 69 0.016
lymph vessel development GO:0001945 27 0.016
gtp metabolic process GO:0046039 4 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
regulation of inflammatory response GO:0050727 2 0.016
cell killing GO:0001906 2 0.016
cell fate specification GO:0001708 68 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
Human Mouse
formation of primary germ layer GO:0001704 62 0.016
negative regulation of protein import into nucleus GO:0042308 2 0.016
regulation of tube size GO:0035150 2 0.016
stem cell fate commitment GO:0048865 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
system process GO:0003008 185 0.015
regulation of response to oxidative stress GO:1902882 2 0.015
hypothalamus cell differentiation GO:0021979 4 0.015
cellular localization GO:0051641 97 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
regulation of programmed cell death GO:0043067 101 0.015
endoderm formation GO:0001706 29 0.015
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.015
response to topologically incorrect protein GO:0035966 2 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of cell activation GO:0050865 1 0.015
negative regulation of mrna processing GO:0050686 1 0.015
negative regulation of muscle cell differentiation GO:0051148 1 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of cell fate specification GO:0042659 20 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
Human Mouse
meiotic cell cycle process GO:1903046 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
regulation of gtpase activity GO:0043087 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
negative regulation of cellular process GO:0048523 283 0.015
cell part morphogenesis GO:0032990 246 0.015
hatching GO:0035188 4 0.015
developmental growth GO:0048589 166 0.015
regulation of sodium ion transport GO:0002028 2 0.015
meiotic chromosome segregation GO:0045132 3 0.014
single organism metabolic process GO:0044710 217 0.014
neurotransmitter transport GO:0006836 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
smooth muscle contraction GO:0006939 2 0.014
regulation of sterol transport GO:0032371 3 0.014
immune effector process GO:0002252 23 0.014
cellular amine metabolic process GO:0044106 2 0.014
mitochondrion organization GO:0007005 4 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
neuroblast differentiation GO:0014016 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
sensory organ development GO:0007423 393 0.014
defense response to fungus GO:0050832 2 0.014
macromolecule localization GO:0033036 54 0.014
neuron neuron synaptic transmission GO:0007270 1 0.013
spermatid development GO:0007286 2 0.013
negative regulation of defense response GO:0031348 2 0.013
regulation of cell proliferation GO:0042127 37 0.013
regulation of cellular component organization GO:0051128 86 0.013
ectodermal cell fate specification GO:0001715 2 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
lymph vessel morphogenesis GO:0036303 25 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
lateral line system development GO:0048925 76 0.013
cell projection morphogenesis GO:0048858 244 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
regulation of protein polymerization GO:0032271 2 0.013
regulation of apoptotic process GO:0042981 98 0.013
cytokinesis GO:0000910 3 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
response to chemical GO:0042221 320 0.013
membrane fusion GO:0061025 2 0.012
female sex differentiation GO:0046660 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
regulation of exocytosis GO:0017157 1 0.012
peptide transport GO:0015833 1 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
Human Mouse
lipid storage GO:0019915 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
blastoderm segmentation GO:0007350 6 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
Human Mouse
positive regulation of camp biosynthetic process GO:0030819 2 0.012
monoamine transport GO:0015844 1 0.012
female meiotic division GO:0007143 2 0.012
appendage development GO:0048736 80 0.012
regulation of blood pressure GO:0008217 1 0.012
kidney development GO:0001822 92 0.012
regulation of biological quality GO:0065008 263 0.012
regulation of filopodium assembly GO:0051489 2 0.012
neuron projection extension GO:1990138 45 0.011
cellular protein localization GO:0034613 20 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
Human Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.011
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.011
regulation of transcription involved in cell fate commitment GO:0060850 1 0.011
single fertilization GO:0007338 3 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
Human Mouse
cell aging GO:0007569 2 0.011
positive regulation of cell killing GO:0031343 2 0.011
renal system development GO:0072001 94 0.011
sphingolipid biosynthetic process GO:0030148 2 0.011
response to other organism GO:0051707 97 0.011
notch signaling pathway GO:0007219 35 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Human Mouse
peptidyl lysine acetylation GO:0018394 2 0.011
single organism cellular localization GO:1902580 46 0.011
regulation of response to stress GO:0080134 36 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
axon extension GO:0048675 45 0.011
endomembrane system organization GO:0010256 13 0.011
neuronal action potential GO:0019228 18 0.011
establishment of epithelial cell polarity GO:0090162 2 0.011
intestinal cholesterol absorption GO:0030299 2 0.011
small molecule metabolic process GO:0044281 77 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.011
gtp catabolic process GO:0006184 2 0.011
cellular response to radiation GO:0071478 4 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
retina development in camera type eye GO:0060041 146 0.011
regulation of organ growth GO:0046620 3 0.011
keratinocyte differentiation GO:0030216 0 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
superoxide metabolic process GO:0006801 2 0.010
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.010
Human Mouse
cellular response to nutrient levels GO:0031669 2 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
oxoacid metabolic process GO:0043436 31 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
chordate embryonic development GO:0043009 271 0.010
membrane invagination GO:0010324 1 0.010
organism emergence from protective structure GO:0071684 4 0.010
skeletal system development GO:0001501 181 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
regulation of nucleotide biosynthetic process GO:0030808 15 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
ras protein signal transduction GO:0007265 7 0.010
amine metabolic process GO:0009308 2 0.010

ef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.083
immune system disease DOID:2914 0 0.027
nervous system disease DOID:863 0 0.018
aplastic anemia DOID:12449 0 0.015
bone marrow disease DOID:4961 0 0.015
anemia DOID:2355 0 0.015
hematopoietic system disease DOID:74 0 0.015
musculoskeletal system disease DOID:17 0 0.014
muscular disease DOID:0080000 0 0.013
cardiovascular system disease DOID:1287 0 0.011
myopathy DOID:423 0 0.010
heart disease DOID:114 0 0.010
cardiomyopathy DOID:0050700 0 0.010
muscle tissue disease DOID:66 0 0.010