Danio rerio

0 known processes

pls1

plastin 1 (I isoform)

(Aliases: wu:fi38g03,zgc:63494)

pls1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 224 0.100
regulation of metal ion transport GO:0010959 4 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.087
aging GO:0007568 2 0.084
cellular modified amino acid metabolic process GO:0006575 3 0.079
response to stress GO:0006950 263 0.077
single organism transport GO:0044765 206 0.075
single organism localization GO:1902578 225 0.075
dicarboxylic acid transport GO:0006835 1 0.071
response to drug GO:0042493 3 0.071
regulation of nitrogen compound metabolic process GO:0051171 251 0.070
multicellular organism growth GO:0035264 4 0.067
signal transduction GO:0007165 455 0.066
ion transport GO:0006811 114 0.063
organic substance biosynthetic process GO:1901576 289 0.062
sulfate transmembrane transport GO:1902358 2 0.060
locomotion GO:0040011 313 0.058
regulation of protein catabolic process GO:0042176 1 0.058
regulation of metabolic process GO:0019222 359 0.057
anion transmembrane transport GO:0098656 12 0.056
anion transport GO:0006820 38 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.056
heart development GO:0007507 313 0.055
transport GO:0006810 220 0.054
cell projection organization GO:0030030 284 0.054
cellular component maintenance GO:0043954 3 0.053
small molecule metabolic process GO:0044281 77 0.053
inner ear receptor stereocilium organization GO:0060122 8 0.052
amino acid transport GO:0006865 2 0.051
mesenchymal cell differentiation GO:0048762 87 0.051
positive regulation of catabolic process GO:0009896 4 0.050
ion transmembrane transport GO:0034220 91 0.050
larval development GO:0002164 2 0.048
protein metabolic process GO:0019538 183 0.048
system process GO:0003008 185 0.048
biosynthetic process GO:0009058 294 0.047
establishment of localization GO:0051234 244 0.047
sensory organ morphogenesis GO:0090596 200 0.046
single organism metabolic process GO:0044710 217 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.044
maintenance of location GO:0051235 4 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.043
lipid storage GO:0019915 1 0.043
cellular macromolecule metabolic process GO:0044260 391 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.042
cellular component movement GO:0006928 335 0.042
organic anion transport GO:0015711 15 0.041
regulation of multicellular organism growth GO:0040014 4 0.040
cellular biosynthetic process GO:0044249 286 0.040
regulation of gene expression GO:0010468 265 0.040
mesenchyme development GO:0060485 127 0.040
organic cyclic compound biosynthetic process GO:1901362 223 0.039
immune system development GO:0002520 191 0.039
cellular component assembly GO:0022607 170 0.039
organic substance transport GO:0071702 58 0.039
epithelial tube morphogenesis GO:0060562 148 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
transmembrane transport GO:0055085 120 0.037
regulation of primary metabolic process GO:0080090 311 0.037
modification dependent protein catabolic process GO:0019941 3 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.037
gene expression GO:0010467 252 0.037
sensory organ development GO:0007423 393 0.035
adherens junction organization GO:0034332 4 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
monoamine transport GO:0015844 1 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
cation transport GO:0006812 81 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
developmental growth GO:0048589 166 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
sulfur compound transport GO:0072348 3 0.030
regulation of establishment of protein localization GO:0070201 4 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
macromolecule modification GO:0043412 111 0.030
lipid metabolic process GO:0006629 52 0.030
response to chemical GO:0042221 320 0.029
regulation of biosynthetic process GO:0009889 250 0.029
heterocycle metabolic process GO:0046483 290 0.028
organic acid metabolic process GO:0006082 31 0.028
cellular component biogenesis GO:0044085 178 0.028
oxoacid metabolic process GO:0043436 31 0.028
response to nutrient GO:0007584 3 0.027
alpha amino acid metabolic process GO:1901605 3 0.027
immune system process GO:0002376 241 0.027
protein targeting to membrane GO:0006612 1 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
cilium morphogenesis GO:0060271 85 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
cellular aldehyde metabolic process GO:0006081 4 0.026
regulation of protein transport GO:0051223 3 0.026
mesenchymal cell development GO:0014031 78 0.026
programmed cell death GO:0012501 119 0.026
epithelial cell differentiation GO:0030855 116 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
regulation of programmed cell death GO:0043067 101 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.025
regulation of cell shape GO:0008360 1 0.025
cell morphogenesis GO:0000902 289 0.025
embryonic heart tube development GO:0035050 133 0.025
embryonic organ development GO:0048568 381 0.025
regulation of signaling GO:0023051 235 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
neural crest cell differentiation GO:0014033 72 0.024
cellular component morphogenesis GO:0032989 336 0.024
positive regulation of nucleotide catabolic process GO:0030813 1 0.024
localization of cell GO:0051674 244 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
eye morphogenesis GO:0048592 144 0.024
regulation of sodium ion transport GO:0002028 2 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
membrane hyperpolarization GO:0060081 1 0.024
protein import into nucleus GO:0006606 3 0.023
cellular amide metabolic process GO:0043603 4 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
meiotic cell cycle process GO:1903046 3 0.023
camera type eye morphogenesis GO:0048593 108 0.023
cell motility GO:0048870 244 0.023
nucleic acid metabolic process GO:0090304 244 0.023
positive regulation of biological process GO:0048518 253 0.023
protein localization to nucleus GO:0034504 3 0.023
cell migration GO:0016477 237 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
regulation of apoptotic process GO:0042981 98 0.022
central nervous system development GO:0007417 387 0.022
regulation of blood pressure GO:0008217 1 0.022
transcription dna templated GO:0006351 181 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
vasculature development GO:0001944 278 0.022
response to hexose GO:0009746 3 0.022
camera type eye development GO:0043010 222 0.022
kidney development GO:0001822 92 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
negative regulation of cell communication GO:0010648 96 0.022
organic acid transport GO:0015849 9 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
negative regulation of cellular metabolic process GO:0031324 77 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
response to endogenous stimulus GO:0009719 83 0.021
regulation of developmental process GO:0050793 247 0.021
organelle organization GO:0006996 227 0.021
positive regulation of transport GO:0051050 2 0.021
regulation of cell communication GO:0010646 232 0.021
regulation of muscle contraction GO:0006937 3 0.021
tube morphogenesis GO:0035239 349 0.021
cellular response to xenobiotic stimulus GO:0071466 35 0.021
embryonic hemopoiesis GO:0035162 53 0.021
eye development GO:0001654 277 0.021
response to alkaloid GO:0043279 2 0.021
regulation of locomotion GO:0040012 55 0.021
response to hormone GO:0009725 48 0.021
eye photoreceptor cell differentiation GO:0001754 45 0.021
response to organic cyclic compound GO:0014070 51 0.020
response to organic substance GO:0010033 153 0.020
adherens junction maintenance GO:0034334 2 0.020
response to monosaccharide GO:0034284 3 0.020
negative regulation of biological process GO:0048519 304 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
membrane fusion GO:0061025 2 0.020
rna metabolic process GO:0016070 219 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
negative regulation of response to stimulus GO:0048585 104 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
organelle assembly GO:0070925 110 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of reproductive process GO:2000241 4 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.018
cellular protein metabolic process GO:0044267 129 0.018
synaptic target recognition GO:0008039 1 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of cell development GO:0060284 100 0.018
photoreceptor cell differentiation GO:0046530 55 0.018
retina morphogenesis in camera type eye GO:0060042 79 0.018
microtubule based process GO:0007017 60 0.018
regeneration GO:0031099 91 0.018
cell projection assembly GO:0030031 64 0.018
cell death GO:0008219 121 0.018
growth GO:0040007 174 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
sensory perception of smell GO:0007608 2 0.018
regulation of cell motility GO:2000145 46 0.018
adult behavior GO:0030534 2 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
sensory perception of chemical stimulus GO:0007606 3 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
monovalent inorganic cation transport GO:0015672 42 0.017
regulation of cell death GO:0010941 103 0.017
auditory receptor cell development GO:0060117 8 0.017
organelle fusion GO:0048284 3 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
regulation of circadian rhythm GO:0042752 4 0.017
death GO:0016265 121 0.017
determination of left right symmetry GO:0007368 179 0.017
auditory receptor cell morphogenesis GO:0002093 4 0.017
phagocytosis GO:0006909 3 0.017
blood vessel endothelial cell migration GO:0043534 18 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
negative regulation of cell death GO:0060548 60 0.017
neural crest cell development GO:0014032 62 0.017
nucleic acid templated transcription GO:0097659 181 0.016
regulation of response to stimulus GO:0048583 269 0.016
carboxylic acid transport GO:0046942 8 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
ear development GO:0043583 127 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
oligopeptide transport GO:0006857 1 0.016
cilium organization GO:0044782 71 0.016
blood vessel morphogenesis GO:0048514 216 0.016
regulation of retina development in camera type eye GO:1902866 2 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
apoptotic process involved in development GO:1902742 2 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.015
positive regulation of cellular process GO:0048522 201 0.015
hormone metabolic process GO:0042445 19 0.015
retina development in camera type eye GO:0060041 146 0.015
single organism membrane fusion GO:0044801 2 0.015
centrosome organization GO:0051297 1 0.015
terpenoid metabolic process GO:0006721 15 0.015
actin filament based movement GO:0030048 1 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
cation transmembrane transport GO:0098655 65 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
metal ion transport GO:0030001 58 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
peptidyl serine modification GO:0018209 2 0.015
negative regulation of cellular process GO:0048523 283 0.014
brain development GO:0007420 293 0.014
heart morphogenesis GO:0003007 156 0.014
negative regulation of signal transduction GO:0009968 94 0.014
single organism organelle organization GO:1902589 199 0.014
nuclear transport GO:0051169 4 0.014
cell junction maintenance GO:0034331 2 0.014
amine metabolic process GO:0009308 2 0.014
endocrine process GO:0050886 2 0.014
tube closure GO:0060606 1 0.014
cellular protein catabolic process GO:0044257 4 0.014
ameboidal type cell migration GO:0001667 143 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
atp catabolic process GO:0006200 4 0.014
neural tube development GO:0021915 62 0.014
glucose import GO:0046323 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.013
cellular lipid metabolic process GO:0044255 36 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
regulation of biological quality GO:0065008 263 0.013
meiotic chromosome segregation GO:0045132 3 0.013
bmp signaling pathway GO:0030509 52 0.013
rna biosynthetic process GO:0032774 181 0.013
sodium ion transmembrane transport GO:0035725 21 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
endocrine system development GO:0035270 65 0.013
cilium assembly GO:0042384 58 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
chordate embryonic development GO:0043009 271 0.013
negative regulation of signaling GO:0023057 96 0.013
protein targeting to nucleus GO:0044744 3 0.013
peptidyl threonine modification GO:0018210 1 0.013
lamellipodium organization GO:0097581 1 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
response to carbohydrate GO:0009743 3 0.013
cell matrix adhesion GO:0007160 4 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
circulatory system process GO:0003013 87 0.013
cell projection morphogenesis GO:0048858 244 0.013
urogenital system development GO:0001655 97 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
apoptotic process GO:0006915 116 0.013
regulation of transcription dna templated GO:0006355 213 0.013
cellular amine metabolic process GO:0044106 2 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
cytoskeleton organization GO:0007010 96 0.013
regulation of proteolysis GO:0030162 24 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.012
cellular sodium ion homeostasis GO:0006883 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
hindbrain development GO:0030902 91 0.012
gtp metabolic process GO:0046039 4 0.012
actin mediated cell contraction GO:0070252 1 0.012
endosomal transport GO:0016197 2 0.012
heart looping GO:0001947 94 0.012
hemopoiesis GO:0030097 183 0.012
centrosome cycle GO:0007098 1 0.012
meiotic nuclear division GO:0007126 4 0.012
diterpenoid metabolic process GO:0016101 15 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
protein complex disassembly GO:0043241 1 0.012
developmental programmed cell death GO:0010623 4 0.012
nuclear import GO:0051170 3 0.012
axoneme assembly GO:0035082 9 0.012
regulation of cell activation GO:0050865 1 0.012
cell part morphogenesis GO:0032990 246 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
specification of symmetry GO:0009799 204 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
inner ear receptor cell development GO:0060119 20 0.012
protein complex assembly GO:0006461 30 0.012
response to glucose GO:0009749 3 0.012
single organism nuclear import GO:1902593 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
cellular ketone metabolic process GO:0042180 11 0.012
mitochondrion organization GO:0007005 4 0.012
angiogenesis GO:0001525 158 0.012
neuron differentiation GO:0030182 353 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of hormone secretion GO:0046883 2 0.012
rna modification GO:0009451 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
response to external stimulus GO:0009605 264 0.012
cell killing GO:0001906 2 0.012
regulation of blood vessel size GO:0050880 2 0.011
neurological system process GO:0050877 62 0.011
cellular response to stress GO:0033554 62 0.011
response to topologically incorrect protein GO:0035966 2 0.011
mechanoreceptor differentiation GO:0042490 37 0.011
negative regulation of gene expression GO:0010629 65 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
tissue migration GO:0090130 37 0.011
stem cell proliferation GO:0072089 4 0.011
cell substrate junction assembly GO:0007044 2 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
epithelium migration GO:0090132 25 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.011
anatomical structure arrangement GO:0048532 2 0.011
hormone transport GO:0009914 2 0.011
activation of mapk activity GO:0000187 3 0.011
regulation of cell migration GO:0030334 40 0.011
neural tube formation GO:0001841 16 0.011
pyrimidine containing compound metabolic process GO:0072527 3 0.011
lipid catabolic process GO:0016042 4 0.011
cellular component disassembly GO:0022411 1 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
blood circulation GO:0008015 87 0.011
response to vitamin GO:0033273 3 0.011
cardiac muscle cell contraction GO:0086003 1 0.011
lymph vessel morphogenesis GO:0036303 25 0.011
head development GO:0060322 303 0.011
cartilage development GO:0051216 96 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of transporter activity GO:0032409 2 0.011
membrane repolarization GO:0086009 2 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.010
digestive system development GO:0055123 289 0.010
monocarboxylic acid transport GO:0015718 5 0.010
specification of organ axis polarity GO:0010084 2 0.010
regulation of localization GO:0032879 104 0.010
cell proliferation GO:0008283 80 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
actin filament polymerization GO:0030041 2 0.010
adherens junction assembly GO:0034333 1 0.010
peptide transport GO:0015833 1 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
determination of bilateral symmetry GO:0009855 204 0.010
nerve development GO:0021675 45 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
hair cell differentiation GO:0035315 32 0.010
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.010
inner ear receptor cell differentiation GO:0060113 29 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010

pls1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.015
inherited metabolic disorder DOID:655 0 0.014