Danio rerio

0 known processes

fgfr4

fibroblast growth factor receptor 4

(Aliases: zgc:111935,wu:fc13h10,MGC111935,etID309818.21)

fgfr4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.989
Human
rna biosynthetic process GO:0032774 181 0.976
head development GO:0060322 303 0.972
Zebrafish
cellular component movement GO:0006928 335 0.969
Human Worm Fly
sensory organ development GO:0007423 393 0.968
sensory organ morphogenesis GO:0090596 200 0.958
embryonic organ development GO:0048568 381 0.944
ear development GO:0043583 127 0.940
regulation of transcription dna templated GO:0006355 213 0.936
ear morphogenesis GO:0042471 64 0.928
axon guidance GO:0007411 86 0.920
Worm
axon development GO:0061564 166 0.913
Worm Fly
digestive tract morphogenesis GO:0048546 231 0.903
Zebrafish Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.901
Human
regulation of macromolecule metabolic process GO:0060255 317 0.898
Human Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.893
Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.890
Human
neuron projection guidance GO:0097485 86 0.886
Worm
morphogenesis of an epithelium GO:0002009 333 0.885
Zebrafish Fly
regulation of biosynthetic process GO:0009889 250 0.875
Human Mouse
skin development GO:0043588 54 0.872
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.870
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.869
Worm Fly
regionalization GO:0003002 274 0.867
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.857
Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.849
tube morphogenesis GO:0035239 349 0.842
Zebrafish Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.836
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.834
brain development GO:0007420 293 0.833
Zebrafish
cellular component morphogenesis GO:0032989 336 0.833
Zebrafish Worm Fly
gastrulation GO:0007369 208 0.832
Zebrafish Fly
axonogenesis GO:0007409 152 0.819
Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.818
Human
regulation of metabolic process GO:0019222 359 0.811
Human Mouse Fly
gene expression GO:0010467 252 0.807
inner ear morphogenesis GO:0042472 63 0.804
vasculature development GO:0001944 278 0.800
cellular nitrogen compound biosynthetic process GO:0044271 218 0.799
Human
positive regulation of rna metabolic process GO:0051254 59 0.793
regulation of rna biosynthetic process GO:2001141 213 0.790
digestive system development GO:0055123 289 0.778
Zebrafish Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.771
Human
immune system development GO:0002520 191 0.756
Fly
nucleic acid templated transcription GO:0097659 181 0.752
regulation of gene expression GO:0010468 265 0.750
regulation of multicellular organismal development GO:2000026 223 0.742
Zebrafish Mouse Fly
localization of cell GO:0051674 244 0.727
Human Worm Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.717
cellular macromolecule metabolic process GO:0044260 391 0.705
Human Zebrafish Rat Worm Fly
heterocycle biosynthetic process GO:0018130 215 0.690
Human
neuron development GO:0048666 262 0.680
Worm Fly
cellular aromatic compound metabolic process GO:0006725 295 0.677
Human
nitrogen compound metabolic process GO:0006807 319 0.660
Human
epidermal cell differentiation GO:0009913 36 0.659
neuron projection morphogenesis GO:0048812 161 0.654
Worm Fly
regulation of stem cell proliferation GO:0072091 2 0.644
retinal ganglion cell axon guidance GO:0031290 35 0.641
forebrain development GO:0030900 96 0.640
blood vessel morphogenesis GO:0048514 216 0.624
hindbrain development GO:0030902 91 0.624
eye development GO:0001654 277 0.618
regulation of nucleic acid templated transcription GO:1903506 213 0.614
eye morphogenesis GO:0048592 144 0.601
chemotaxis GO:0006935 104 0.600
Worm
regulation of developmental process GO:0050793 247 0.592
Zebrafish Mouse Fly
generation of neurons GO:0048699 385 0.584
Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.577
Fly
determination of bilateral symmetry GO:0009855 204 0.576
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.570
Human
cell motility GO:0048870 244 0.566
Human Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.566
Human Mouse
regulation of endodermal cell fate specification GO:0042663 15 0.560
Zebrafish
rna metabolic process GO:0016070 219 0.560
transcription from rna polymerase ii promoter GO:0006366 80 0.553
central nervous system development GO:0007417 387 0.552
Zebrafish Fly
biosynthetic process GO:0009058 294 0.544
Human Mouse
cell projection organization GO:0030030 284 0.534
Zebrafish Worm Fly
organic substance biosynthetic process GO:1901576 289 0.525
Human Mouse
regulation of organ morphogenesis GO:2000027 35 0.518
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.517
Human
developmental growth GO:0048589 166 0.507
Zebrafish Fly
positive regulation of transcription dna templated GO:0045893 57 0.507
macromolecule biosynthetic process GO:0009059 227 0.501
Human
negative regulation of biological process GO:0048519 304 0.490
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.486
Human
regulation of rna metabolic process GO:0051252 224 0.485
stem cell maintenance GO:0019827 4 0.484
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.474
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.473
Human
taxis GO:0042330 109 0.469
Worm
cellular biosynthetic process GO:0044249 286 0.456
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.454
Human
inner ear development GO:0048839 126 0.454
regulation of embryonic development GO:0045995 47 0.453
Zebrafish
hemopoiesis GO:0030097 183 0.448
camera type eye development GO:0043010 222 0.436
forebrain neuron development GO:0021884 7 0.425
regulation of cell communication GO:0010646 232 0.423
Human Fly
renal system development GO:0072001 94 0.419
Fly
blood vessel development GO:0001568 246 0.414
stem cell differentiation GO:0048863 117 0.414
Fly
mechanoreceptor differentiation GO:0042490 37 0.410
negative regulation of programmed cell death GO:0043069 58 0.407
compound eye development GO:0048749 2 0.400
positive regulation of stem cell proliferation GO:2000648 1 0.399
regulation of cellular biosynthetic process GO:0031326 245 0.398
Human Mouse
regulation of primary metabolic process GO:0080090 311 0.388
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.387
Zebrafish Mouse Fly
regulation of mesenchymal cell proliferation GO:0010464 1 0.386
segmentation GO:0035282 97 0.386
response to chemical GO:0042221 320 0.385
Human Zebrafish Mouse Rat Worm
digestive tract development GO:0048565 265 0.384
Zebrafish Worm Fly
neuron projection development GO:0031175 180 0.384
Worm Fly
embryonic hemopoiesis GO:0035162 53 0.382
stem cell proliferation GO:0072089 4 0.376
inner ear receptor cell differentiation GO:0060113 29 0.376
retina development in camera type eye GO:0060041 146 0.361
embryonic eye morphogenesis GO:0048048 30 0.360
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.360
Human
cell proliferation GO:0008283 80 0.357
Human Zebrafish Mouse
epiboly GO:0090504 41 0.357
positive regulation of cellular process GO:0048522 201 0.356
Human Mouse Fly
regulation of axonogenesis GO:0050770 32 0.352
Fly
dorsal ventral pattern formation GO:0009953 125 0.352
Zebrafish
formation of primary germ layer GO:0001704 62 0.350
Zebrafish Fly
cell part morphogenesis GO:0032990 246 0.345
Zebrafish Worm Fly
urogenital system development GO:0001655 97 0.343
Fly
epidermis development GO:0008544 48 0.324
positive regulation of biological process GO:0048518 253 0.323
Human Mouse Fly
regulation of nervous system development GO:0051960 90 0.316
Fly
skeletal system development GO:0001501 181 0.316
positive regulation of metabolic process GO:0009893 108 0.314
Human Fly
response to external stimulus GO:0009605 264 0.313
Worm Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.313
signal transduction GO:0007165 455 0.310
Human Zebrafish Mouse Rat Worm Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.299
epithelial cell differentiation GO:0030855 116 0.298
Fly
olfactory placode development GO:0071698 12 0.295
Zebrafish
ameboidal type cell migration GO:0001667 143 0.293
Fly
kidney development GO:0001822 92 0.291
chordate embryonic development GO:0043009 271 0.287
anterior posterior pattern specification GO:0009952 152 0.285
regulation of cell death GO:0010941 103 0.285
mesoderm morphogenesis GO:0048332 51 0.283
Fly
convergent extension GO:0060026 118 0.283
larval development GO:0002164 2 0.281
Worm Fly
somite development GO:0061053 96 0.280
epithelial tube morphogenesis GO:0060562 148 0.276
Fly
cell migration GO:0016477 237 0.275
Human Worm Fly
regulation of biological quality GO:0065008 263 0.272
Zebrafish Mouse Fly
pancreas development GO:0031016 84 0.270
Zebrafish
bmp signaling pathway GO:0030509 52 0.264
somitogenesis GO:0001756 87 0.263
neural tube development GO:0021915 62 0.260
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.258
Human
cell projection morphogenesis GO:0048858 244 0.258
Zebrafish Worm Fly
endodermal cell fate specification GO:0001714 17 0.248
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.242
mesoderm formation GO:0001707 43 0.238
Fly
lymph vessel morphogenesis GO:0036303 25 0.235
regulation of cell cycle GO:0051726 52 0.225
hair cell differentiation GO:0035315 32 0.221
heart development GO:0007507 313 0.218
Zebrafish Fly
mesenchymal cell proliferation GO:0010463 1 0.213
positive regulation of biosynthetic process GO:0009891 68 0.212
Human
positive regulation of gene expression GO:0010628 71 0.209
regulation of apoptotic process GO:0042981 98 0.209
endodermal cell fate commitment GO:0001711 18 0.207
Zebrafish Fly
negative regulation of cell development GO:0010721 26 0.204
Fly
regulation of stem cell differentiation GO:2000736 4 0.202
transcription dna templated GO:0006351 181 0.199
central nervous system neuron development GO:0021954 29 0.197
specification of symmetry GO:0009799 204 0.196
Zebrafish
regeneration GO:0031099 91 0.195
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.190
morphogenesis of an epithelial sheet GO:0002011 49 0.190
regulation of gastrulation GO:0010470 24 0.189
Zebrafish
neuroblast proliferation GO:0007405 2 0.187
positive regulation of macromolecule metabolic process GO:0010604 93 0.184
Human Fly
developmental growth involved in morphogenesis GO:0060560 86 0.178
Fly
cellular amine metabolic process GO:0044106 2 0.177
cell fate specification GO:0001708 68 0.175
Zebrafish Fly
positive regulation of map kinase activity GO:0043406 3 0.175
Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.169
stem cell division GO:0017145 1 0.169
positive regulation of nervous system development GO:0051962 25 0.169
closure of optic fissure GO:0061386 6 0.168
cell fate commitment GO:0045165 99 0.166
Zebrafish Mouse Fly
growth GO:0040007 174 0.165
Zebrafish Fly
glial cell migration GO:0008347 3 0.163
Fly
regulation of multicellular organism growth GO:0040014 4 0.162
negative regulation of cell death GO:0060548 60 0.162
regulation of anatomical structure morphogenesis GO:0022603 130 0.157
Zebrafish Mouse Fly
wnt signaling pathway GO:0016055 80 0.154
apoptotic process GO:0006915 116 0.154
cell death GO:0008219 121 0.152
mesodermal cell differentiation GO:0048333 21 0.152
Fly
diencephalon development GO:0021536 58 0.151
cellular ketone metabolic process GO:0042180 11 0.150
Human Mouse
single organism nuclear import GO:1902593 3 0.148
aging GO:0007568 2 0.147
immune system process GO:0002376 241 0.147
Fly
embryonic camera type eye development GO:0031076 29 0.147
determination of left right symmetry GO:0007368 179 0.146
Zebrafish
cell cycle GO:0007049 93 0.146
regulation of cell migration GO:0030334 40 0.146
cell morphogenesis GO:0000902 289 0.144
Zebrafish Worm Fly
gland development GO:0048732 143 0.144
Zebrafish Fly
regulation of cellular metabolic process GO:0031323 320 0.143
Human Mouse Fly
peripheral nervous system development GO:0007422 55 0.143
regulation of locomotion GO:0040012 55 0.137
circulatory system process GO:0003013 87 0.135
positive regulation of cell differentiation GO:0045597 30 0.134
muscle tissue development GO:0060537 110 0.133
Zebrafish
locomotion GO:0040011 313 0.133
Human Worm Fly
somatic stem cell maintenance GO:0035019 1 0.133
single organism reproductive process GO:0044702 40 0.132
Worm Fly
vasculogenesis GO:0001570 41 0.132
angiogenesis GO:0001525 158 0.131
regulation of cellular amine metabolic process GO:0033238 0 0.130
neuron projection extension GO:1990138 45 0.129
Fly
multicellular organism growth GO:0035264 4 0.129
semicircular canal morphogenesis GO:0048752 18 0.128
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.127
somatic muscle development GO:0007525 4 0.126
Fly
organelle organization GO:0006996 227 0.126
Zebrafish
peripheral nervous system neuron differentiation GO:0048934 28 0.123
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.123
single organism organelle organization GO:1902589 199 0.121
Zebrafish
forebrain generation of neurons GO:0021872 14 0.120
endothelial cell fate commitment GO:0060839 3 0.119
regulation of epithelial cell proliferation GO:0050678 3 0.119
endocrine system development GO:0035270 65 0.117
stem cell development GO:0048864 82 0.116
cell surface receptor signaling pathway GO:0007166 325 0.115
Human Zebrafish Mouse Rat Worm
proepicardium development GO:0003342 4 0.115
cardiocyte differentiation GO:0035051 44 0.112
Fly
semicircular canal development GO:0060872 24 0.112
positive regulation of cellular metabolic process GO:0031325 94 0.110
Human Fly
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.110
Zebrafish
type b pancreatic cell development GO:0003323 4 0.109
ectodermal placode development GO:0071696 37 0.107
Zebrafish
lens development in camera type eye GO:0002088 22 0.106
regulation of cell proliferation GO:0042127 37 0.106
Human Mouse
regulation of reproductive process GO:2000241 4 0.106
regulation of neurogenesis GO:0050767 87 0.105
Fly
determination of heart left right asymmetry GO:0061371 117 0.104
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.104
negative regulation of neurogenesis GO:0050768 20 0.103
Fly
death GO:0016265 121 0.103
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.103
exocrine pancreas development GO:0031017 28 0.103
retina morphogenesis in camera type eye GO:0060042 79 0.101
regulation of neuron differentiation GO:0045664 56 0.100
Fly
regulation of cell motility GO:2000145 46 0.100
negative regulation of bmp signaling pathway GO:0030514 13 0.099
cranial nerve development GO:0021545 42 0.097
Zebrafish
post anal tail morphogenesis GO:0036342 19 0.097
Zebrafish
response to stress GO:0006950 263 0.097
Zebrafish Fly
cellular amino acid metabolic process GO:0006520 7 0.097
negative regulation of cell communication GO:0010648 96 0.094
lipid storage GO:0019915 1 0.093
neuron fate specification GO:0048665 20 0.092
response to organic substance GO:0010033 153 0.091
Human Zebrafish Mouse Rat Worm
photoreceptor cell fate commitment GO:0046552 1 0.090
neural retina development GO:0003407 49 0.090
regulation of bmp signaling pathway GO:0030510 39 0.090
heart morphogenesis GO:0003007 156 0.089
positive regulation of cellular biosynthetic process GO:0031328 68 0.089
Human
negative regulation of apoptotic process GO:0043066 55 0.088
lymphangiogenesis GO:0001946 25 0.088
enzyme linked receptor protein signaling pathway GO:0007167 106 0.088
Human Zebrafish Mouse Rat Worm
regulation of signaling GO:0023051 235 0.086
Human Fly
tube formation GO:0035148 25 0.086
regulation of synapse assembly GO:0051963 3 0.086
axon regeneration GO:0031103 14 0.085
negative regulation of cellular process GO:0048523 283 0.085
Zebrafish Fly
left right pattern formation GO:0060972 19 0.085
lymph vessel development GO:0001945 27 0.085
amine metabolic process GO:0009308 2 0.084
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.084
posterior lateral line development GO:0048916 38 0.084
Zebrafish
regulation of chondrocyte differentiation GO:0032330 1 0.083
myeloid cell differentiation GO:0030099 86 0.083
forebrain neuron differentiation GO:0021879 14 0.082
regulation of cellular component movement GO:0051270 55 0.081
cell differentiation in spinal cord GO:0021515 40 0.080
blood circulation GO:0008015 87 0.078
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.078
exocrine system development GO:0035272 28 0.078
mesenchymal cell development GO:0014031 78 0.077
morphogenesis of embryonic epithelium GO:0016331 30 0.077
female gonad development GO:0008585 4 0.075
extrinsic apoptotic signaling pathway GO:0097191 3 0.075
protein targeting to nucleus GO:0044744 3 0.075
notochord development GO:0030903 54 0.075
phosphorus metabolic process GO:0006793 109 0.075
Human Zebrafish Rat Worm Fly
response to nutrient GO:0007584 3 0.073
otic vesicle morphogenesis GO:0071600 34 0.073
ectodermal placode morphogenesis GO:0071697 32 0.073
Zebrafish
outflow tract morphogenesis GO:0003151 1 0.072
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.072
Zebrafish Fly
endodermal cell differentiation GO:0035987 19 0.071
Zebrafish Fly
embryonic camera type eye formation GO:0060900 10 0.071
heart jogging GO:0003146 40 0.071
myeloid cell development GO:0061515 32 0.071
small molecule metabolic process GO:0044281 77 0.071
Human Mouse
biological adhesion GO:0022610 40 0.070
positive regulation of cell development GO:0010720 25 0.070
synaptic target recognition GO:0008039 1 0.068
mesenchymal cell differentiation GO:0048762 87 0.068
organic acid metabolic process GO:0006082 31 0.067
Human Mouse
striated muscle cell development GO:0055002 108 0.067
Fly
negative regulation of gene expression GO:0010629 65 0.067
regulation of wnt signaling pathway GO:0030111 53 0.067
neurological system process GO:0050877 62 0.066
negative regulation of nervous system development GO:0051961 22 0.066
Fly
skeletal system morphogenesis GO:0048705 102 0.066
regulation of protein targeting GO:1903533 2 0.066
rhombomere development GO:0021546 19 0.066
ectodermal placode formation GO:0060788 26 0.065
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.064
regulation of programmed cell death GO:0043067 101 0.064
embryonic heart tube development GO:0035050 133 0.064
regulation of axon extension GO:0030516 24 0.063
Fly
regulation of protein transport GO:0051223 3 0.063
embryo development ending in birth or egg hatching GO:0009792 271 0.063
Worm
negative regulation of developmental growth GO:0048640 9 0.063
Fly
negative regulation of metabolic process GO:0009892 86 0.062
neural precursor cell proliferation GO:0061351 20 0.062
Zebrafish
response to wounding GO:0009611 116 0.062
Zebrafish
chemosensory behavior GO:0007635 1 0.062
germ line stem cell maintenance GO:0030718 2 0.062
muscle cell development GO:0055001 115 0.062
Fly
programmed cell death GO:0012501 119 0.061
embryonic limb morphogenesis GO:0030326 2 0.061
melanin metabolic process GO:0006582 2 0.060
negative regulation of stem cell differentiation GO:2000737 2 0.060
nephron morphogenesis GO:0072028 2 0.060
cell substrate adhesion GO:0031589 4 0.060
embryonic epithelial tube formation GO:0001838 17 0.059
positive regulation of neurogenesis GO:0050769 24 0.059
regulation of cell shape GO:0008360 1 0.059
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.059
mesenchyme development GO:0060485 127 0.058
Zebrafish Fly
regulation of phosphorus metabolic process GO:0051174 43 0.058
Human Fly
protein localization to nucleus GO:0034504 3 0.057
regulation of developmental growth GO:0048638 38 0.057
Fly
connective tissue development GO:0061448 99 0.056
negative regulation of macromolecule metabolic process GO:0010605 76 0.056
posterior lateral line system development GO:0048915 46 0.056
Zebrafish
regulation of establishment of protein localization GO:0070201 4 0.056
morphogenesis of a branching structure GO:0001763 21 0.055
Fly
nerve development GO:0021675 45 0.055
Zebrafish
regulation of cell differentiation GO:0045595 142 0.055
Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 52 0.055
Mouse
smoothened signaling pathway GO:0007224 30 0.055
regulation of organ growth GO:0046620 3 0.055
olfactory lobe development GO:0021988 4 0.054
central nervous system neuron differentiation GO:0021953 74 0.054
notochord cell differentiation GO:0060034 18 0.053
cell proliferation in midbrain GO:0033278 4 0.053
Zebrafish
response to light stimulus GO:0009416 46 0.053
female sex differentiation GO:0046660 4 0.052
developmental cell growth GO:0048588 52 0.052
Fly
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.051
telencephalon development GO:0021537 14 0.051
primary neural tube formation GO:0014020 1 0.051
negative regulation of synapse assembly GO:0051964 2 0.050
erythrocyte differentiation GO:0030218 54 0.050
cellular component assembly involved in morphogenesis GO:0010927 107 0.049
Zebrafish
regulation of endodermal cell differentiation GO:1903224 15 0.049
Zebrafish
regulation of cell size GO:0008361 29 0.049
Fly
aorta development GO:0035904 4 0.049
heart valve morphogenesis GO:0003179 8 0.049
positive regulation of jun kinase activity GO:0043507 2 0.049
maintenance of location GO:0051235 4 0.048
negative regulation of transcription dna templated GO:0045892 45 0.048
forebrain neuron fate commitment GO:0021877 1 0.048
organonitrogen compound metabolic process GO:1901564 74 0.048
regulation of cellular component organization GO:0051128 86 0.047
Human Worm Fly
regulation of cell activation GO:0050865 1 0.047
single organism metabolic process GO:0044710 217 0.047
Human Mouse Fly
epithelial cell development GO:0002064 42 0.047
Fly
negative regulation of cell fate specification GO:0009996 11 0.046
Zebrafish
negative regulation of cell proliferation GO:0008285 8 0.046
forebrain regionalization GO:0021871 4 0.046
lateral inhibition GO:0046331 1 0.046
regulation of cell development GO:0060284 100 0.045
Fly
transcription from rna polymerase iii promoter GO:0006383 1 0.044
axon extension GO:0048675 45 0.044
Fly
gliogenesis GO:0042063 45 0.044
Fly
cellular response to external stimulus GO:0071496 2 0.043
lens fiber cell development GO:0070307 3 0.043
positive regulation of endothelial cell differentiation GO:0045603 2 0.043
positive regulation of developmental process GO:0051094 50 0.042
Mouse
regulation of immune system process GO:0002682 34 0.042
Fly
rhombomere formation GO:0021594 12 0.041
cartilage development GO:0051216 96 0.041
septum transversum development GO:0003343 4 0.041
canonical wnt signaling pathway GO:0060070 48 0.040
embryonic skeletal system morphogenesis GO:0048704 93 0.040
regulation of skeletal muscle tissue development GO:0048641 4 0.040
oxoacid metabolic process GO:0043436 31 0.039
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.039
positive regulation of cellular amine metabolic process GO:0033240 0 0.038
muscle structure development GO:0061061 196 0.038
Worm Fly
embryonic heart tube morphogenesis GO:0003143 108 0.038
muscle fiber development GO:0048747 52 0.038
Fly
peripheral nervous system neuron development GO:0048935 22 0.038
mesoderm development GO:0007498 88 0.037
Zebrafish Fly
muscle cell migration GO:0014812 4 0.037
response to oxygen containing compound GO:1901700 55 0.037
determination of ventral identity GO:0048264 21 0.037
negative regulation of developmental process GO:0051093 65 0.036
Zebrafish Fly
sprouting angiogenesis GO:0002040 53 0.036
keratinocyte differentiation GO:0030216 0 0.036
behavior GO:0007610 74 0.036
Worm
patterning of blood vessels GO:0001569 15 0.035
lymphatic endothelial cell differentiation GO:0060836 1 0.035
neuronal stem cell maintenance GO:0097150 2 0.035
regulation of synapse organization GO:0050807 3 0.035
convergent extension involved in gastrulation GO:0060027 71 0.035
positive regulation of neural precursor cell proliferation GO:2000179 1 0.035
glomerulus development GO:0032835 27 0.035
endoderm formation GO:0001706 29 0.035
Zebrafish Fly
establishment of localization GO:0051234 244 0.034
Worm
nephron development GO:0072006 31 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
polarized epithelial cell differentiation GO:0030859 4 0.034
photoreceptor cell differentiation GO:0046530 55 0.034
cell proliferation in forebrain GO:0021846 3 0.034
regulation of anatomical structure size GO:0090066 33 0.034
Fly
development of primary female sexual characteristics GO:0046545 4 0.033
pronephros development GO:0048793 69 0.033
otolith development GO:0048840 32 0.033
regulation of circadian rhythm GO:0042752 4 0.033
carbohydrate derivative metabolic process GO:1901135 61 0.033
positive regulation of cell communication GO:0010647 56 0.032
Human Fly
regulation of response to stimulus GO:0048583 269 0.032
Human Fly
auditory receptor cell development GO:0060117 8 0.032
hard palate development GO:0060022 4 0.032
neuron fate commitment GO:0048663 26 0.032
heart looping GO:0001947 94 0.032
carbohydrate biosynthetic process GO:0016051 1 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.031
lipid metabolic process GO:0006629 52 0.031
Human Mouse
regulation of epithelial to mesenchymal transition GO:0010717 3 0.031
mesodermal cell migration GO:0008078 12 0.031
Fly
motor neuron axon guidance GO:0008045 23 0.031
cell cycle process GO:0022402 53 0.031
tube closure GO:0060606 1 0.031
negative regulation of endodermal cell fate specification GO:0042664 8 0.030
Zebrafish
endocrine pancreas development GO:0031018 27 0.030
endothelial cell migration GO:0043542 19 0.030
regulation of localization GO:0032879 104 0.030
neuron recognition GO:0008038 18 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
tissue regeneration GO:0042246 74 0.030
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.030
Human Mouse
protein metabolic process GO:0019538 183 0.030
Human Zebrafish Rat Worm Fly
ventricular system development GO:0021591 12 0.030
regulation of signal transduction GO:0009966 225 0.030
Human Fly
mesodermal cell fate specification GO:0007501 12 0.029
actin filament based process GO:0030029 64 0.029
negative regulation of response to stimulus GO:0048585 104 0.029
endoderm development GO:0007492 49 0.029
Zebrafish Fly
regulation of canonical wnt signaling pathway GO:0060828 34 0.029
nephron epithelium morphogenesis GO:0072088 1 0.029
kidney epithelium development GO:0072073 23 0.029
cognition GO:0050890 1 0.028
heart contraction GO:0060047 71 0.028
determination of dorsal ventral asymmetry GO:0048262 34 0.028
epidermal cell fate specification GO:0009957 4 0.028
positive regulation of cell adhesion GO:0045785 1 0.028

fgfr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.280
colon carcinoma DOID:1520 0 0.135
large intestine cancer DOID:5672 0 0.135
colon cancer DOID:219 0 0.135
gastrointestinal system cancer DOID:3119 0 0.135
intestinal cancer DOID:10155 0 0.135
cancer DOID:162 0 0.135
disease of cellular proliferation DOID:14566 0 0.135
organ system cancer DOID:0050686 0 0.135
colorectal cancer DOID:9256 0 0.135
bone development disease DOID:0080006 0 0.068
bone disease DOID:0080001 0 0.068
musculoskeletal system disease DOID:17 0 0.068
connective tissue disease DOID:65 0 0.068
sensory system disease DOID:0050155 0 0.060
eye and adnexa disease DOID:1492 0 0.060
nervous system disease DOID:863 0 0.060
eye disease DOID:5614 0 0.060
cardiovascular system disease DOID:1287 0 0.047