Danio rerio

38 known processes

akt2

v-akt murine thymoma viral oncogene homolog 2

(Aliases: cb945)

akt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.601
Human Rat
chordate embryonic development GO:0043009 271 0.562
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.497
Yeast Rat
regulation of biological quality GO:0065008 263 0.479
Fly
cellular component movement GO:0006928 335 0.475
Human Zebrafish Rat Fly
neuron differentiation GO:0030182 353 0.467
Fly
rna metabolic process GO:0016070 219 0.464
Yeast Rat
response to stress GO:0006950 263 0.427
Rat Fly
cellular aromatic compound metabolic process GO:0006725 295 0.415
Yeast Mouse Rat
localization of cell GO:0051674 244 0.378
Human Zebrafish Rat Fly
lateral inhibition GO:0046331 1 0.358
regulation of macromolecule metabolic process GO:0060255 317 0.358
Human Yeast Mouse Rat
nuclear migration GO:0007097 3 0.352
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.348
Human Yeast Mouse Rat Worm Fly
gene expression GO:0010467 252 0.338
Yeast Rat
negative regulation of cellular process GO:0048523 283 0.338
regulation of cellular metabolic process GO:0031323 320 0.334
Human Yeast Mouse Rat
regulation of macromolecule biosynthetic process GO:0010556 225 0.314
Human Rat
neuron projection development GO:0031175 180 0.314
Fly
skeletal system development GO:0001501 181 0.309
regulation of primary metabolic process GO:0080090 311 0.309
Human Yeast Mouse Rat
nuclear transport GO:0051169 4 0.305
myotube differentiation GO:0014902 45 0.302
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.300
Yeast Mouse Rat
larval development GO:0002164 2 0.298
Worm
tube morphogenesis GO:0035239 349 0.294
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.290
regulation of multicellular organismal development GO:2000026 223 0.270
Zebrafish Fly
macromolecule biosynthetic process GO:0009059 227 0.264
Human Rat
biosynthetic process GO:0009058 294 0.261
Human Rat
protein localization to nucleus GO:0034504 3 0.260
modification dependent protein catabolic process GO:0019941 3 0.246
organic cyclic compound metabolic process GO:1901360 301 0.244
Yeast Mouse Rat
regulation of gene expression GO:0010468 265 0.244
Yeast Rat
regulation of developmental process GO:0050793 247 0.244
Zebrafish Fly
developmental growth GO:0048589 166 0.242
Fly
regulation of multicellular organism growth GO:0040014 4 0.239
Fly
single organism transport GO:0044765 206 0.237
regulation of response to stimulus GO:0048583 269 0.237
Mouse Rat Fly
transport GO:0006810 220 0.231
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.222
Mouse Rat
positive regulation of cellular process GO:0048522 201 0.221
Human Mouse Rat Fly
regulation of transcription dna templated GO:0006355 213 0.218
Rat
negative regulation of biological process GO:0048519 304 0.216
response to chemical GO:0042221 320 0.216
Human Mouse Rat Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.214
establishment of localization GO:0051234 244 0.209
cellular biosynthetic process GO:0044249 286 0.207
Human Rat
regulation of synapse organization GO:0050807 3 0.197
Fly
protein import into nucleus GO:0006606 3 0.195
protein targeting to nucleus GO:0044744 3 0.193
organic substance biosynthetic process GO:1901576 289 0.191
Human Rat
positive regulation of cellular component biogenesis GO:0044089 3 0.189
dorsal ventral pattern formation GO:0009953 125 0.189
single organism metabolic process GO:0044710 217 0.183
Human Yeast Mouse Fly
establishment of protein localization to organelle GO:0072594 4 0.181
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.180
Yeast Mouse Rat
cell migration GO:0016477 237 0.175
Zebrafish Rat Fly
mechanosensory behavior GO:0007638 2 0.174
cell motility GO:0048870 244 0.171
Human Zebrafish Rat Fly
wnt signaling pathway GO:0016055 80 0.169
single organism localization GO:1902578 225 0.169
protein metabolic process GO:0019538 183 0.167
Human Yeast Mouse Rat Worm Fly
single organism nuclear import GO:1902593 3 0.167
regulation of nucleic acid templated transcription GO:1903506 213 0.166
Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.165
Human Rat
regulation of metabolic process GO:0019222 359 0.165
Human Yeast Mouse Rat
regulation of multicellular organismal process GO:0051239 277 0.164
Zebrafish Fly
immune system development GO:0002520 191 0.162
Zebrafish
central nervous system development GO:0007417 387 0.158
Zebrafish
generation of neurons GO:0048699 385 0.154
Zebrafish Fly
positive regulation of gene expression GO:0010628 71 0.149
Rat
cellular protein metabolic process GO:0044267 129 0.145
Human Yeast Mouse Rat Worm Fly
regulation of dna templated transcription in response to stress GO:0043620 0 0.144
cellular response to external stimulus GO:0071496 2 0.141
cellular protein catabolic process GO:0044257 4 0.139
regulation of cellular component organization GO:0051128 86 0.138
Yeast Mouse Fly
cartilage development GO:0051216 96 0.137
positive regulation of biological process GO:0048518 253 0.136
cellular component assembly GO:0022607 170 0.136
Yeast Fly
response to radiation GO:0009314 51 0.135
immune system process GO:0002376 241 0.135
Zebrafish Fly
multicellular organism reproduction GO:0032504 35 0.134
Fly
maintenance of location GO:0051235 4 0.133
Fly
gastrulation with mouth forming second GO:0001702 44 0.133
cellular component morphogenesis GO:0032989 336 0.131
Fly
cellular ketone metabolic process GO:0042180 11 0.129
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.128
heterocycle biosynthetic process GO:0018130 215 0.127
Rat
determination of bilateral symmetry GO:0009855 204 0.126
positive regulation of rna metabolic process GO:0051254 59 0.125
Rat
myoblast fusion GO:0007520 10 0.124
Fly
cell fate commitment GO:0045165 99 0.123
embryo development ending in birth or egg hatching GO:0009792 271 0.122
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.120
heterocycle metabolic process GO:0046483 290 0.119
Yeast Mouse Rat
synapse assembly GO:0007416 9 0.119
Fly
regulation of protein transport GO:0051223 3 0.119
Mouse
lipid storage GO:0019915 1 0.118
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
Yeast Mouse Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.117
Yeast Mouse Rat
single organism reproductive process GO:0044702 40 0.117
Fly
synaptic target recognition GO:0008039 1 0.117
regulation of protein import into nucleus GO:0042306 2 0.115
multicellular organism growth GO:0035264 4 0.115
Fly
transcription dna templated GO:0006351 181 0.115
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.114
Fly
organelle organization GO:0006996 227 0.114
Yeast Zebrafish Mouse
somatic stem cell maintenance GO:0035019 1 0.111
regulation of biosynthetic process GO:0009889 250 0.111
Human Rat
negative regulation of cytoplasmic transport GO:1903650 2 0.110
response to external stimulus GO:0009605 264 0.110
Rat Fly
positive regulation of transport GO:0051050 2 0.108
regulation of signal transduction GO:0009966 225 0.108
Mouse Rat
head development GO:0060322 303 0.107
Zebrafish
protein import GO:0017038 3 0.106
nitrogen compound metabolic process GO:0006807 319 0.105
Yeast Mouse Rat
cellular response to stress GO:0033554 62 0.105
Fly
embryonic organ morphogenesis GO:0048562 274 0.103
aging GO:0007568 2 0.103
Worm
peptide transport GO:0015833 1 0.102
response to carbohydrate GO:0009743 3 0.102
developmental process involved in reproduction GO:0003006 27 0.101
Fly
regulation of meiotic cell cycle GO:0051445 1 0.100
negative regulation of catabolic process GO:0009895 3 0.100
regulation of binding GO:0051098 3 0.099
determination of ventral identity GO:0048264 21 0.099
hindbrain development GO:0030902 91 0.098
Zebrafish
cellular response to organic substance GO:0071310 105 0.097
Human Mouse Rat Worm Fly
peptidyl serine phosphorylation GO:0018105 1 0.096
Rat Worm
nuclear import GO:0051170 3 0.096
ameboidal type cell migration GO:0001667 143 0.095
Zebrafish Fly
digestive tract development GO:0048565 265 0.095
Zebrafish
protein modification process GO:0036211 100 0.095
Human Yeast Mouse Rat Worm Fly
determination of left right symmetry GO:0007368 179 0.094
positive regulation of cellular biosynthetic process GO:0031328 68 0.094
Human Rat
regulation of signaling GO:0023051 235 0.094
Mouse Rat Fly
response to abiotic stimulus GO:0009628 122 0.094
Rat
positive regulation of metabolic process GO:0009893 108 0.093
Human Mouse Rat
positive regulation of transcription dna templated GO:0045893 57 0.093
Rat
ubiquitin dependent protein catabolic process GO:0006511 3 0.093
neuron development GO:0048666 262 0.092
Fly
regulation of oocyte development GO:0060281 3 0.092
regulation of dna replication GO:0006275 3 0.092
regulation of epithelial cell proliferation GO:0050678 3 0.092
actin polymerization or depolymerization GO:0008154 2 0.092
response to mechanical stimulus GO:0009612 24 0.091
single organism organelle organization GO:1902589 199 0.091
Yeast Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.090
hematopoietic or lymphoid organ development GO:0048534 191 0.090
Zebrafish
connective tissue development GO:0061448 99 0.090
embryonic limb morphogenesis GO:0030326 2 0.090
regulation of establishment of protein localization GO:0070201 4 0.090
Mouse
reproductive process GO:0022414 40 0.088
Fly
protein complex disassembly GO:0043241 1 0.088
embryonic skeletal system morphogenesis GO:0048704 93 0.088
locomotion GO:0040011 313 0.088
Human Zebrafish Rat Fly
regulation of cellular biosynthetic process GO:0031326 245 0.087
Human Rat
modification dependent macromolecule catabolic process GO:0043632 3 0.087
cell projection organization GO:0030030 284 0.086
Fly
nucleic acid templated transcription GO:0097659 181 0.086
Rat
negative regulation of protein phosphorylation GO:0001933 4 0.086
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.084
Fly
pronuclear migration GO:0035046 1 0.083
aromatic compound biosynthetic process GO:0019438 217 0.082
Rat
hormone secretion GO:0046879 2 0.081
muscle structure development GO:0061061 196 0.080
Fly
growth GO:0040007 174 0.080
Fly
skeletal system morphogenesis GO:0048705 102 0.079
stem cell maintenance GO:0019827 4 0.079
negative regulation of protein localization to nucleus GO:1900181 2 0.078
stem cell development GO:0048864 82 0.077
meiotic nuclear division GO:0007126 4 0.075
actin filament polymerization GO:0030041 2 0.075
response to wounding GO:0009611 116 0.074
Fly
epithelial structure maintenance GO:0010669 8 0.074
hemopoiesis GO:0030097 183 0.073
Zebrafish
cell matrix adhesion GO:0007160 4 0.073
neuron projection morphogenesis GO:0048812 161 0.073
embryonic organ development GO:0048568 381 0.073
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.073
Human
extrinsic apoptotic signaling pathway GO:0097191 3 0.072
negative regulation of signal transduction GO:0009968 94 0.072
lymph vessel development GO:0001945 27 0.071
morphogenesis of an epithelium GO:0002009 333 0.071
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.071
enzyme linked receptor protein signaling pathway GO:0007167 106 0.071
Human Mouse Worm Fly
organic acid metabolic process GO:0006082 31 0.071
Human
regulation of protein catabolic process GO:0042176 1 0.071
cellular localization GO:0051641 97 0.071
Zebrafish Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.070
regulation of protein complex assembly GO:0043254 3 0.070
cellular response to nutrient levels GO:0031669 2 0.070
negative regulation of intracellular protein transport GO:0090317 3 0.070
regulation of intracellular protein transport GO:0033157 3 0.070
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.069
Human Mouse Worm Fly
positive regulation of cellular metabolic process GO:0031325 94 0.069
Human Mouse Rat
blood vessel morphogenesis GO:0048514 216 0.069
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.068
Rat
anterior posterior pattern specification GO:0009952 152 0.068
regulation of cellular ketone metabolic process GO:0010565 7 0.068
Human
regulation of rna biosynthetic process GO:2001141 213 0.068
Rat
cellular amine metabolic process GO:0044106 2 0.067
regionalization GO:0003002 274 0.067
ear morphogenesis GO:0042471 64 0.067
primary neural tube formation GO:0014020 1 0.067
cellular component biogenesis GO:0044085 178 0.067
Yeast Fly
brain development GO:0007420 293 0.067
Zebrafish
vasculature development GO:0001944 278 0.066
Zebrafish
positive regulation of gtp catabolic process GO:0033126 1 0.066
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.066
positive regulation of oocyte development GO:0060282 1 0.065
positive regulation of macromolecule metabolic process GO:0010604 93 0.065
Human Mouse Rat
mesenchymal cell development GO:0014031 78 0.065
nucleobase containing compound biosynthetic process GO:0034654 205 0.065
Rat
heart development GO:0007507 313 0.065
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.065
inner ear morphogenesis GO:0042472 63 0.064
cellular protein modification process GO:0006464 100 0.063
Human Yeast Mouse Rat Worm Fly
negative regulation of signaling GO:0023057 96 0.063
Fly
epithelial tube morphogenesis GO:0060562 148 0.063
Zebrafish
negative regulation of intracellular transport GO:0032387 3 0.062
regulation of cytoplasmic transport GO:1903649 4 0.062
chemotaxis GO:0006935 104 0.062
Rat
regulation of cell communication GO:0010646 232 0.062
Mouse Rat Fly
oxoacid metabolic process GO:0043436 31 0.061
Human
response to glucose GO:0009749 3 0.060
rna biosynthetic process GO:0032774 181 0.060
Rat
canonical wnt signaling pathway GO:0060070 48 0.060
lipid metabolic process GO:0006629 52 0.059
Human Fly
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.059
regulation of protein localization to nucleus GO:1900180 2 0.058
positive regulation of catabolic process GO:0009896 4 0.057
Human Mouse
mesoderm development GO:0007498 88 0.056
Zebrafish
cell substrate adhesion GO:0031589 4 0.056
protein complex biogenesis GO:0070271 30 0.056
myeloid cell differentiation GO:0030099 86 0.056
cell part morphogenesis GO:0032990 246 0.056
regulation of anatomical structure morphogenesis GO:0022603 130 0.055
Zebrafish Fly
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.055
stem cell proliferation GO:0072089 4 0.055
Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 2 0.054
ear development GO:0043583 127 0.054
negative regulation of cell communication GO:0010648 96 0.054
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.054
negative regulation of protein transport GO:0051224 3 0.054
regulation of embryonic development GO:0045995 47 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.053
cellular component disassembly GO:0022411 1 0.053
signal transduction GO:0007165 455 0.053
Human Yeast Mouse Rat Worm Fly
regulation of erythrocyte differentiation GO:0045646 2 0.053
regulation of cell cycle GO:0051726 52 0.053
regulation of synapse assembly GO:0051963 3 0.053
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.053
Rat
negative regulation of protein import into nucleus GO:0042308 2 0.052
regulation of protein ubiquitination GO:0031396 3 0.051
multicellular organismal reproductive process GO:0048609 35 0.051
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.051
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.050
synaptic growth at neuromuscular junction GO:0051124 2 0.050
Fly
negative regulation of metabolic process GO:0009892 86 0.049
Rat
positive regulation of cell adhesion GO:0045785 1 0.049
glucose homeostasis GO:0042593 1 0.049
axonogenesis GO:0007409 152 0.049
cell projection morphogenesis GO:0048858 244 0.049
regeneration GO:0031099 91 0.048
Fly
specification of symmetry GO:0009799 204 0.048
stem cell differentiation GO:0048863 117 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.048
Rat
wound healing GO:0042060 90 0.048
regulation of apoptotic process GO:0042981 98 0.048
regulation of growth GO:0040008 42 0.047
Fly
regulation of wnt signaling pathway GO:0030111 53 0.047
cell death GO:0008219 121 0.046
apoptotic process GO:0006915 116 0.046
regulation of collateral sprouting in absence of injury GO:0048696 4 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
Mouse
cell cycle arrest GO:0007050 1 0.045
cell proliferation GO:0008283 80 0.045
Zebrafish Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.044
Rat
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.044
Human
regulation of cell death GO:0010941 103 0.044
tube closure GO:0060606 1 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.044
amine metabolic process GO:0009308 2 0.044
digestive tract morphogenesis GO:0048546 231 0.044
Zebrafish
regulation of carbohydrate metabolic process GO:0006109 4 0.043
Human
hormone transport GO:0009914 2 0.043
embryonic heart tube development GO:0035050 133 0.043
Zebrafish
heart morphogenesis GO:0003007 156 0.043
cellular response to extracellular stimulus GO:0031668 2 0.043
renal system development GO:0072001 94 0.042
sensory organ morphogenesis GO:0090596 200 0.042
Zebrafish
protein stabilization GO:0050821 2 0.042
negative regulation of epithelial cell proliferation GO:0050680 1 0.042
mesoderm morphogenesis GO:0048332 51 0.041
Zebrafish
system process GO:0003008 185 0.040
muscle organ development GO:0007517 101 0.040
embryonic skeletal system development GO:0048706 97 0.040
negative regulation of ras protein signal transduction GO:0046580 1 0.040
eye development GO:0001654 277 0.040
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
anterior posterior axis specification GO:0009948 20 0.040
regulation of protein polymerization GO:0032271 2 0.040
regulation of skeletal muscle tissue development GO:0048641 4 0.040
response to oxygen containing compound GO:1901700 55 0.040
Human Mouse Rat Worm Fly
negative regulation of cellular catabolic process GO:0031330 3 0.040
neuroblast differentiation GO:0014016 1 0.039
regulation of nucleoside metabolic process GO:0009118 2 0.039
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.039
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.039
spermatid differentiation GO:0048515 2 0.039
macromolecular complex disassembly GO:0032984 1 0.038
appendage morphogenesis GO:0035107 56 0.038
regulation of protein targeting GO:1903533 2 0.037
Mouse
formation of primary germ layer GO:0001704 62 0.037
Zebrafish
cellular response to starvation GO:0009267 1 0.037
small molecule metabolic process GO:0044281 77 0.037
Human Mouse
regulation of skeletal muscle fiber development GO:0048742 2 0.037
regulation of filopodium assembly GO:0051489 2 0.037
regulation of cellular response to growth factor stimulus GO:0090287 35 0.037
regulation of hormone levels GO:0010817 21 0.037
positive regulation of neuron apoptotic process GO:0043525 1 0.037
astrocyte differentiation GO:0048708 1 0.036
centrosome organization GO:0051297 1 0.036
pharyngeal muscle development GO:0043282 4 0.036
gastrulation GO:0007369 208 0.036
Zebrafish
heart looping GO:0001947 94 0.036
response to nutrient GO:0007584 3 0.036
spermatid development GO:0007286 2 0.036
myotube cell development GO:0014904 35 0.036
regulation of epithelial to mesenchymal transition GO:0010717 3 0.036
cytokinesis GO:0000910 3 0.036
erythrocyte differentiation GO:0030218 54 0.036
muscle tissue development GO:0060537 110 0.035
oocyte maturation GO:0001556 4 0.035
cellular carbohydrate metabolic process GO:0044262 4 0.035
Human
pericardium development GO:0060039 1 0.035
negative regulation of secretion GO:0051048 2 0.035
syncytium formation by plasma membrane fusion GO:0000768 12 0.035
Fly
guanosine containing compound metabolic process GO:1901068 4 0.035
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.034
Rat
gland development GO:0048732 143 0.034
neural tube formation GO:0001841 16 0.034
Zebrafish
muscle cell differentiation GO:0042692 139 0.034
Fly
striated muscle tissue development GO:0014706 110 0.034
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.034
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.034
macromolecular complex subunit organization GO:0043933 74 0.034
Yeast
response to vitamin GO:0033273 3 0.034
protein localization GO:0008104 40 0.034
Mouse
response to hexose GO:0009746 3 0.033
establishment of localization in cell GO:0051649 77 0.033
Zebrafish Mouse
cellular response to growth factor stimulus GO:0071363 39 0.033
anion transport GO:0006820 38 0.033
Human
chromosome organization GO:0051276 31 0.033
regulation of reproductive process GO:2000241 4 0.033
gamete generation GO:0007276 33 0.033
Fly
muscle cell migration GO:0014812 4 0.033
peripheral nervous system development GO:0007422 55 0.033
Mouse
regulation of immune system process GO:0002682 34 0.033
Fly
lymph vessel morphogenesis GO:0036303 25 0.033
negative regulation of cellular metabolic process GO:0031324 77 0.032
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.032
Mouse Rat
regulation of response to extracellular stimulus GO:0032104 1 0.032
pyruvate metabolic process GO:0006090 1 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
Rat
cell cycle g1 s phase transition GO:0044843 1 0.032
ectodermal placode development GO:0071696 37 0.032
regulation of organelle assembly GO:1902115 4 0.032
regulation of cellular protein metabolic process GO:0032268 52 0.032
Mouse Rat
positive regulation of multicellular organismal process GO:0051240 52 0.032
Fly
single organism biosynthetic process GO:0044711 71 0.032
Human
epithelial cell migration GO:0010631 25 0.032
Zebrafish Fly
tissue regeneration GO:0042246 74 0.032
positive regulation of protein complex assembly GO:0031334 2 0.031
macromolecule localization GO:0033036 54 0.031
Human Mouse Fly
synapse organization GO:0050808 21 0.031
Fly
gtp metabolic process GO:0046039 4 0.031
Mouse
fin regeneration GO:0031101 51 0.031
pigment cell differentiation GO:0050931 38 0.031
regulation of programmed cell death GO:0043067 101 0.031
positive regulation of gtpase activity GO:0043547 1 0.031
Mouse
cellular response to chemical stimulus GO:0070887 157 0.031
Human Mouse Rat Worm Fly
hard palate development GO:0060022 4 0.030
axon guidance GO:0007411 86 0.030
determination of heart left right asymmetry GO:0061371 117 0.030
regulation of gtpase activity GO:0043087 2 0.030
Mouse
protein heterooligomerization GO:0051291 1 0.030
negative regulation of chromosome organization GO:2001251 1 0.030
apoptotic process involved in development GO:1902742 2 0.030
sexual reproduction GO:0019953 36 0.030
Fly
regulation of cell differentiation GO:0045595 142 0.030
Fly
regulation of gtp catabolic process GO:0033124 2 0.030
Mouse
negative regulation of gene expression GO:0010629 65 0.029
Rat
macromolecular complex assembly GO:0065003 35 0.029
Yeast
gtp catabolic process GO:0006184 2 0.029
Mouse
epithelial cell differentiation GO:0030855 116 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
Human Mouse
protein complex localization GO:0031503 1 0.029
neuroblast proliferation GO:0007405 2 0.028
Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
muscle cell development GO:0055001 115 0.028
single organism cellular localization GO:1902580 46 0.028
Zebrafish Mouse
regulation of dna metabolic process GO:0051052 11 0.028
anatomical structure homeostasis GO:0060249 36 0.028
positive regulation of stress activated mapk cascade GO:0032874 3 0.028
epithelial tube formation GO:0072175 19 0.028
Zebrafish
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
Mouse
cell cell signaling GO:0007267 52 0.028
Fly
negative regulation of protein kinase activity GO:0006469 4 0.027
positive regulation of nucleoside metabolic process GO:0045979 1 0.027
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.027
Human Mouse Worm Fly
single organismal cell cell adhesion GO:0016337 29 0.027
oocyte development GO:0048599 14 0.027
erythrocyte homeostasis GO:0034101 55 0.027
cell adhesion GO:0007155 40 0.027
homeostatic process GO:0042592 142 0.027
dna templated transcription elongation GO:0006354 3 0.027
multi organism process GO:0051704 134 0.026
Fly
skeletal muscle tissue development GO:0007519 67 0.026
angiogenesis GO:0001525 158 0.026
Zebrafish
neurotransmitter transport GO:0006836 2 0.026
neural tube development GO:0021915 62 0.026
Zebrafish
regulation of synaptic plasticity GO:0048167 1 0.026
Fly
phosphorylation GO:0016310 69 0.026
Human Yeast Mouse Rat Worm Fly
regulation of cellular protein catabolic process GO:1903362 1 0.026
primitive hemopoiesis GO:0060215 27 0.026
protein complex assembly GO:0006461 30 0.026
cellular response to hypoxia GO:0071456 1 0.026
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.025
regulation of cell matrix adhesion GO:0001952 1 0.025
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.025
regulation of cellular component size GO:0032535 30 0.025
Fly
peptidyl lysine acetylation GO:0018394 2 0.025
biological adhesion GO:0022610 40 0.025
otic vesicle morphogenesis GO:0071600 34 0.025
positive regulation of notch signaling pathway GO:0045747 3 0.025
convergent extension involved in gastrulation GO:0060027 71 0.025
cell growth GO:0016049 57 0.025
Fly
proteasomal protein catabolic process GO:0010498 2 0.025
embryonic skeletal joint development GO:0072498 3 0.025
negative regulation of mapk cascade GO:0043409 4 0.025
cellular response to oxygen levels GO:0071453 1 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
regulation of organelle organization GO:0033043 29 0.024
Mouse
cell morphogenesis GO:0000902 289 0.024
Fly
i kappab kinase nf kappab signaling GO:0007249 4 0.024
osteoclast differentiation GO:0030316 1 0.024
camera type eye morphogenesis GO:0048593 108 0.024
Zebrafish
regulation of blood vessel size GO:0050880 2 0.024
positive regulation of biosynthetic process GO:0009891 68 0.024
Human Rat
germ line stem cell division GO:0042078 1 0.024
multi organism cellular process GO:0044764 2 0.024
myeloid leukocyte differentiation GO:0002573 15 0.024
regulation of myotube differentiation GO:0010830 2 0.024
branching morphogenesis of a nerve GO:0048755 4 0.023
positive regulation of nucleotide catabolic process GO:0030813 1 0.023
Mouse
positive regulation of jnk cascade GO:0046330 3 0.023
forebrain development GO:0030900 96 0.023
otic vesicle development GO:0071599 42 0.023
carbohydrate homeostasis GO:0033500 1 0.023
muscle fiber development GO:0048747 52 0.023
negative regulation of developmental process GO:0051093 65 0.023
Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.023
negative regulation of programmed cell death GO:0043069 58 0.023
lymphangiogenesis GO:0001946 25 0.023
positive regulation of neuron death GO:1901216 1 0.023
death GO:0016265 121 0.023
regulation of organ growth GO:0046620 3 0.023
Fly
regulation of neuron differentiation GO:0045664 56 0.023
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
Rat
sprouting angiogenesis GO:0002040 53 0.022
Zebrafish
somitogenesis GO:0001756 87 0.022
cell aging GO:0007569 2 0.022
blood vessel development GO:0001568 246 0.022
Zebrafish
positive chemotaxis GO:0050918 5 0.022
Rat
regulation of stem cell differentiation GO:2000736 4 0.022
response to alkaloid GO:0043279 2 0.022
positive regulation of protein polymerization GO:0032273 2 0.022
embryonic epithelial tube formation GO:0001838 17 0.021
Zebrafish
internal protein amino acid acetylation GO:0006475 2 0.021
positive regulation of developmental process GO:0051094 50 0.021
Fly

akt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.060
Human
inherited metabolic disorder DOID:655 0 0.060
disease of anatomical entity DOID:7 0 0.034
cardiovascular system disease DOID:1287 0 0.034
myopathy DOID:423 0 0.026
muscular disease DOID:0080000 0 0.026
heart disease DOID:114 0 0.026
cardiomyopathy DOID:0050700 0 0.026
intrinsic cardiomyopathy DOID:0060036 0 0.026
musculoskeletal system disease DOID:17 0 0.026
muscle tissue disease DOID:66 0 0.026