Danio rerio

76 known processes

kiss1rb

KISS1 receptor b

(Aliases: si:ch211-157p22.8)

kiss1rb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.942
organic substance biosynthetic process GO:1901576 289 0.762
rna biosynthetic process GO:0032774 181 0.698
female sex differentiation GO:0046660 4 0.596
urea transmembrane transport GO:0071918 9 0.576
heterocycle biosynthetic process GO:0018130 215 0.564
nitrogen compound metabolic process GO:0006807 319 0.493
organic cyclic compound metabolic process GO:1901360 301 0.418
biosynthetic process GO:0009058 294 0.413
regulation of cellular metabolic process GO:0031323 320 0.348
steroid hormone mediated signaling pathway GO:0043401 9 0.321
regulation of macromolecule biosynthetic process GO:0010556 225 0.277
signal transduction GO:0007165 455 0.274
cellular nitrogen compound metabolic process GO:0034641 290 0.267
cellular nitrogen compound biosynthetic process GO:0044271 218 0.237
cellular macromolecule biosynthetic process GO:0034645 224 0.214
regulation of transcription dna templated GO:0006355 213 0.206
negative regulation of growth rate GO:0045967 1 0.184
cellular biosynthetic process GO:0044249 286 0.182
regulation of primary metabolic process GO:0080090 311 0.177
gene expression GO:0010467 252 0.177
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.172
heterocycle metabolic process GO:0046483 290 0.171
nucleic acid templated transcription GO:0097659 181 0.168
nucleobase containing compound metabolic process GO:0006139 274 0.163
regulation of rna metabolic process GO:0051252 224 0.161
ovulation cycle process GO:0022602 2 0.150
aromatic compound biosynthetic process GO:0019438 217 0.149
regulation of gene expression GO:0010468 265 0.129
regulation of nitrogen compound metabolic process GO:0051171 251 0.129
regulation of cellular biosynthetic process GO:0031326 245 0.128
macromolecule biosynthetic process GO:0009059 227 0.128
negative regulation of biological process GO:0048519 304 0.127
Mouse Rat
regulation of biosynthetic process GO:0009889 250 0.126
cyclic nucleotide biosynthetic process GO:0009190 18 0.125
rna metabolic process GO:0016070 219 0.123
female gonad development GO:0008585 4 0.122
purine ribonucleotide biosynthetic process GO:0009152 20 0.118
regulation of epithelial cell proliferation GO:0050678 3 0.113
ovulation cycle GO:0042698 2 0.113
cellular aromatic compound metabolic process GO:0006725 295 0.112
cell surface receptor signaling pathway GO:0007166 325 0.109
nucleobase containing compound biosynthetic process GO:0034654 205 0.105
transcription dna templated GO:0006351 181 0.105
response to external stimulus GO:0009605 264 0.100
aging GO:0007568 2 0.097
pericardium morphogenesis GO:0003344 1 0.096
locomotion GO:0040011 313 0.094
Mouse
nucleotide biosynthetic process GO:0009165 21 0.093
positive regulation of lipid metabolic process GO:0045834 1 0.088
androgen metabolic process GO:0008209 2 0.087
cellular response to hormone stimulus GO:0032870 39 0.086
single organism metabolic process GO:0044710 217 0.086
Rat
regulation of metabolic process GO:0019222 359 0.086
opioid receptor signaling pathway GO:0038003 3 0.085
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.083
development of primary female sexual characteristics GO:0046545 4 0.083
positive regulation of biological process GO:0048518 253 0.079
light adaption GO:0036367 1 0.079
purine nucleotide biosynthetic process GO:0006164 20 0.078
regulation of purine nucleotide metabolic process GO:1900542 17 0.078
regulation of cellular amine metabolic process GO:0033238 0 0.078
regulation of cell communication GO:0010646 232 0.076
Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.073
signal transduction by phosphorylation GO:0023014 18 0.072
Rat
regulation of multicellular organismal process GO:0051239 277 0.069
meiotic nuclear division GO:0007126 4 0.068
regulation of macromolecule metabolic process GO:0060255 317 0.065
ovarian follicle development GO:0001541 2 0.065
single organism carbohydrate metabolic process GO:0044723 12 0.063
erk1 and erk2 cascade GO:0070371 4 0.059
system process GO:0003008 185 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.057
negative regulation of cell communication GO:0010648 96 0.057
regulation of nucleotide metabolic process GO:0006140 17 0.057
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.055
regulation of erk1 and erk2 cascade GO:0070372 4 0.055
positive regulation of molecular function GO:0044093 33 0.054
Rat
regulation of developmental process GO:0050793 247 0.054
regulation of catalytic activity GO:0050790 55 0.053
Rat
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.053
positive regulation of cellular amine metabolic process GO:0033240 0 0.052
larval development GO:0002164 2 0.050
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.050
regulation of cellular ketone metabolic process GO:0010565 7 0.049
negative regulation of hormone secretion GO:0046888 2 0.049
cellular amide metabolic process GO:0043603 4 0.049
sister chromatid cohesion GO:0007062 2 0.048
cognition GO:0050890 1 0.047
negative regulation of metabolic process GO:0009892 86 0.047
cellular response to estradiol stimulus GO:0071392 1 0.046
carbon dioxide transmembrane transport GO:0035378 1 0.046
cellular response to estrogen stimulus GO:0071391 24 0.046
generation of neurons GO:0048699 385 0.045
regulation of nucleic acid templated transcription GO:1903506 213 0.044
positive regulation of rna metabolic process GO:0051254 59 0.043
response to alkaloid GO:0043279 2 0.043
organonitrogen compound metabolic process GO:1901564 74 0.043
urogenital system development GO:0001655 97 0.043
response to organic substance GO:0010033 153 0.042
regulation of reactive oxygen species metabolic process GO:2000377 2 0.042
response to glucocorticoid GO:0051384 1 0.042
regulation of reproductive process GO:2000241 4 0.042
peptide metabolic process GO:0006518 1 0.041
calcium ion transport into cytosol GO:0060402 3 0.041
negative regulation of camp biosynthetic process GO:0030818 7 0.041
positive regulation of cellular metabolic process GO:0031325 94 0.040
cellular amine metabolic process GO:0044106 2 0.040
astrocyte differentiation GO:0048708 1 0.039
regulation of hormone secretion GO:0046883 2 0.038
Rat
ammonium transmembrane transport GO:0072488 2 0.037
response to cortisol GO:0051414 1 0.037
amine metabolic process GO:0009308 2 0.037
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.037
regulation of camp metabolic process GO:0030814 9 0.036
positive regulation of response to stimulus GO:0048584 80 0.036
Rat
regulation of rna biosynthetic process GO:2001141 213 0.036
response to chemical GO:0042221 320 0.036
regulation of multicellular organismal metabolic process GO:0044246 2 0.035
regulation of dna replication GO:0006275 3 0.035
multicellular organismal water homeostasis GO:0050891 1 0.035
renal absorption GO:0070293 1 0.034
response to food GO:0032094 1 0.034
response to corticosteroid GO:0031960 1 0.033
positive regulation of secretion by cell GO:1903532 1 0.032
Rat
regulation of mapk cascade GO:0043408 14 0.031
Rat
developmental growth involved in morphogenesis GO:0060560 86 0.031
membrane lipid biosynthetic process GO:0046467 2 0.030
organonitrogen compound biosynthetic process GO:1901566 47 0.030
positive regulation of epithelial cell proliferation GO:0050679 1 0.029
cell cycle g1 s phase transition GO:0044843 1 0.029
response to vitamin GO:0033273 3 0.029
ribose phosphate metabolic process GO:0019693 27 0.028
carboxylic acid transport GO:0046942 8 0.028
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
fatty acid biosynthetic process GO:0006633 4 0.028
negative regulation of dna replication GO:0008156 2 0.028
regulation of endocrine process GO:0044060 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
response to organic cyclic compound GO:0014070 51 0.027
positive regulation of transport GO:0051050 2 0.027
Rat
brain development GO:0007420 293 0.026
peripheral nervous system neuron development GO:0048935 22 0.026
lipid metabolic process GO:0006629 52 0.026
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
cellular response to steroid hormone stimulus GO:0071383 31 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
multicellular organismal response to stress GO:0033555 2 0.025
regulation of skeletal muscle tissue development GO:0048641 4 0.025
er nucleus signaling pathway GO:0006984 2 0.025
positive regulation of cell cycle GO:0045787 3 0.024
response to dexamethasone GO:0071548 1 0.024
nitric oxide biosynthetic process GO:0006809 2 0.024
response to drug GO:0042493 3 0.024
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.024
positive regulation of chromatin modification GO:1903310 1 0.024
regulation of molecular function GO:0065009 70 0.024
Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
cyclic nucleotide metabolic process GO:0009187 18 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
regulation of signaling GO:0023051 235 0.023
Rat
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.023
compound eye development GO:0048749 2 0.022
neurotransmitter secretion GO:0007269 2 0.022
positive regulation of rna biosynthetic process GO:1902680 57 0.022
multicellular organismal metabolic process GO:0044236 2 0.022
purine ribonucleotide metabolic process GO:0009150 27 0.022
multicellular organismal signaling GO:0035637 22 0.022
regulation of cell death GO:0010941 103 0.021
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.021
eye development GO:0001654 277 0.021
positive regulation of camp metabolic process GO:0030816 2 0.021
negative regulation of muscle tissue development GO:1901862 2 0.021
organophosphate metabolic process GO:0019637 37 0.021
neuron migration GO:0001764 22 0.020
sensory organ development GO:0007423 393 0.020
pericardium development GO:0060039 1 0.020
axon development GO:0061564 166 0.020
positive regulation of glucose transport GO:0010828 1 0.020
intracellular estrogen receptor signaling pathway GO:0030520 3 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
negative regulation of defense response GO:0031348 2 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.019
positive regulation of wound healing GO:0090303 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
response to unfolded protein GO:0006986 2 0.019
positive regulation of cyclase activity GO:0031281 6 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
Rat
epithelial cell development GO:0002064 42 0.019
regulation of signal transduction GO:0009966 225 0.019
Rat
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
regulation of gtpase activity GO:0043087 2 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
response to external biotic stimulus GO:0043207 97 0.018
catenin import into nucleus GO:0035411 2 0.018
programmed cell death GO:0012501 119 0.018
regulation of behavior GO:0050795 24 0.018
cyclic purine nucleotide metabolic process GO:0052652 18 0.018
steroid hormone secretion GO:0035929 1 0.017
collagen metabolic process GO:0032963 2 0.017
negative regulation of signaling GO:0023057 96 0.017
neurological system process GO:0050877 62 0.017
phosphorus metabolic process GO:0006793 109 0.017
Rat
regulation of phosphorus metabolic process GO:0051174 43 0.017
Rat
positive regulation of cellular process GO:0048522 201 0.017
mapk cascade GO:0000165 18 0.017
Rat
regulation of protein ubiquitination GO:0031396 3 0.017
stem cell fate commitment GO:0048865 1 0.017
negative regulation of innate immune response GO:0045824 2 0.017
dna biosynthetic process GO:0071897 3 0.017
phagocytosis GO:0006909 3 0.017
organic hydroxy compound transport GO:0015850 14 0.017
response to steroid hormone GO:0048545 35 0.017
oocyte maturation GO:0001556 4 0.016
stem cell proliferation GO:0072089 4 0.016
response to ketone GO:1901654 1 0.016
regulation of rho protein signal transduction GO:0035023 2 0.016
cellular protein metabolic process GO:0044267 129 0.016
Rat
positive regulation of map kinase activity GO:0043406 3 0.016
Rat
phosphate containing compound metabolic process GO:0006796 108 0.016
Rat
cellular ketone metabolic process GO:0042180 11 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
Mouse Rat
bone remodeling GO:0046849 2 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
regulation of carbohydrate biosynthetic process GO:0043255 1 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
apoptotic process GO:0006915 116 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
calcium ion homeostasis GO:0055074 19 0.015
cellular protein modification process GO:0006464 100 0.015
Rat
lipid oxidation GO:0034440 1 0.015
regulation of steroid hormone secretion GO:2000831 1 0.015
negative regulation of secretion GO:0051048 2 0.015
gas transport GO:0015669 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
regulation of cellular ph reduction GO:0032847 1 0.015
multicellular organism growth GO:0035264 4 0.015
regulation of hormone metabolic process GO:0032350 6 0.015
single organism biosynthetic process GO:0044711 71 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
negative regulation of cell death GO:0060548 60 0.015
interspecies interaction between organisms GO:0044419 4 0.014
phosphorylation GO:0016310 69 0.014
Rat
regulation of gtp catabolic process GO:0033124 2 0.014
anterior lateral line nerve glial cell development GO:0048939 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
cellular component morphogenesis GO:0032989 336 0.014
response to growth factor GO:0070848 39 0.014
regulation of growth rate GO:0040009 1 0.014
regulation of metal ion transport GO:0010959 4 0.014
primary amino compound metabolic process GO:1901160 1 0.014
regulation of skeletal muscle fiber development GO:0048742 2 0.014
developmental programmed cell death GO:0010623 4 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
regulation of response to stimulus GO:0048583 269 0.014
Rat
regulation of cyclase activity GO:0031279 12 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
endocrine hormone secretion GO:0060986 2 0.013
multicellular organism reproduction GO:0032504 35 0.013
ph reduction GO:0045851 1 0.013
cellular response to drug GO:0035690 1 0.013
camp biosynthetic process GO:0006171 11 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
regulation of lyase activity GO:0051339 12 0.013
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.013
anterior lateral line system development GO:0048898 9 0.013
protein metabolic process GO:0019538 183 0.013
Rat
immune system process GO:0002376 241 0.013
neuron development GO:0048666 262 0.013
small molecule metabolic process GO:0044281 77 0.013
negative regulation of phosphate metabolic process GO:0045936 13 0.013
activation of mapk activity GO:0000187 3 0.013
Rat
regulation of tube size GO:0035150 2 0.013
negative regulation of locomotion GO:0040013 18 0.013
Mouse
negative regulation of reproductive process GO:2000242 3 0.013
fatty acid beta oxidation GO:0006635 1 0.012
single organism behavior GO:0044708 24 0.012
axon extension GO:0048675 45 0.012
regulation of myotube differentiation GO:0010830 2 0.012
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.012
regulation of cell development GO:0060284 100 0.012
regulation of fatty acid metabolic process GO:0019217 1 0.012
defense response GO:0006952 47 0.012
establishment of localization GO:0051234 244 0.012
Rat
water homeostasis GO:0030104 4 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
developmental growth GO:0048589 166 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
forebrain development GO:0030900 96 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
sex determination GO:0007530 1 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
regulation of camp mediated signaling GO:0043949 1 0.012
thermosensory behavior GO:0040040 1 0.012
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.011
regulation of calcium ion transport GO:0051924 2 0.011
interaction with host GO:0051701 4 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
ribonucleotide biosynthetic process GO:0009260 20 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
response to stress GO:0006950 263 0.011
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
macromolecule modification GO:0043412 111 0.011
Rat
atrial ventricular junction remodeling GO:0003294 2 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
organic substance transport GO:0071702 58 0.011
Rat
growth GO:0040007 174 0.011
ribose phosphate biosynthetic process GO:0046390 20 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
Rat
germ line stem cell maintenance GO:0030718 2 0.011
nucleoside triphosphate biosynthetic process GO:0009142 2 0.011
regulation of tissue remodeling GO:0034103 2 0.011
morphogenesis of an epithelial fold GO:0060571 1 0.011
positive regulation of camp biosynthetic process GO:0030819 2 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 7 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of bone mineralization GO:0030500 2 0.011
locomotor rhythm GO:0045475 3 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of biological quality GO:0065008 263 0.011
Rat
phosphatidylinositol mediated signaling GO:0048015 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.010
regulation of phosphorylation GO:0042325 26 0.010
Rat
catechol containing compound biosynthetic process GO:0009713 2 0.010
ventral spinal cord interneuron fate commitment GO:0060579 3 0.010
protein localization GO:0008104 40 0.010
hormone transport GO:0009914 2 0.010
Rat
regulation of lipid transport GO:0032368 4 0.010
response to topologically incorrect protein GO:0035966 2 0.010
trabecula morphogenesis GO:0061383 2 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
response to glucose GO:0009749 3 0.010
regulation of apoptotic process GO:0042981 98 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
regulation of collagen metabolic process GO:0010712 2 0.010
amide biosynthetic process GO:0043604 1 0.010
transport GO:0006810 220 0.010
Rat

kiss1rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.020
disease of anatomical entity DOID:7 0 0.020
anemia DOID:2355 0 0.020
hematopoietic system disease DOID:74 0 0.020
disease of metabolism DOID:0014667 0 0.012