Danio rerio

0 known processes

srd5a2a

steroid-5-alpha-reductase, alpha polypeptide 2a

(Aliases: wu:fk70d02,zgc:112208,zgc:109942)

srd5a2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
xenobiotic metabolic process GO:0006805 4 0.163
fat soluble vitamin biosynthetic process GO:0042362 2 0.151
embryonic organ development GO:0048568 381 0.135
small molecule metabolic process GO:0044281 77 0.131
aging GO:0007568 2 0.123
specification of symmetry GO:0009799 204 0.118
larval development GO:0002164 2 0.117
hematopoietic or lymphoid organ development GO:0048534 191 0.107
generation of neurons GO:0048699 385 0.105
organic cyclic compound metabolic process GO:1901360 301 0.105
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.104
organic substance biosynthetic process GO:1901576 289 0.102
Mouse
lipid catabolic process GO:0016042 4 0.102
determination of bilateral symmetry GO:0009855 204 0.101
multicellular organism growth GO:0035264 4 0.096
diterpenoid metabolic process GO:0016101 15 0.095
response to amphetamine GO:0001975 1 0.094
negative regulation of cellular process GO:0048523 283 0.089
response to drug GO:0042493 3 0.086
single organism metabolic process GO:0044710 217 0.085
Mouse
maintenance of location GO:0051235 4 0.084
regulation of cellular metabolic process GO:0031323 320 0.082
organic cyclic compound biosynthetic process GO:1901362 223 0.081
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.081
cellular biosynthetic process GO:0044249 286 0.078
Mouse
cellular component morphogenesis GO:0032989 336 0.075
digestive tract development GO:0048565 265 0.075
nitrogen compound metabolic process GO:0006807 319 0.074
lipid storage GO:0019915 1 0.071
phagocytosis GO:0006909 3 0.070
cell projection morphogenesis GO:0048858 244 0.070
aromatic compound biosynthetic process GO:0019438 217 0.066
diterpenoid biosynthetic process GO:0016102 7 0.065
organism emergence from protective structure GO:0071684 4 0.064
cellular lipid catabolic process GO:0044242 3 0.064
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.061
circulatory system process GO:0003013 87 0.060
nucleobase containing compound biosynthetic process GO:0034654 205 0.060
actin filament based process GO:0030029 64 0.060
cellular hormone metabolic process GO:0034754 19 0.059
Mouse
immune system development GO:0002520 191 0.058
negative regulation of biological process GO:0048519 304 0.057
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.057
morphogenesis of an epithelium GO:0002009 333 0.057
isoprenoid biosynthetic process GO:0008299 7 0.056
cellular response to methanol GO:0071405 4 0.056
regulation of rna metabolic process GO:0051252 224 0.055
cellular aldehyde metabolic process GO:0006081 4 0.055
single organism organelle organization GO:1902589 199 0.055
regulation of metabolic process GO:0019222 359 0.055
heart development GO:0007507 313 0.053
response to biotic stimulus GO:0009607 97 0.053
regulation of rna biosynthetic process GO:2001141 213 0.053
response to amine GO:0014075 1 0.053
response to external stimulus GO:0009605 264 0.052
response to other organism GO:0051707 97 0.052
retinoid metabolic process GO:0001523 15 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.050
localization of cell GO:0051674 244 0.049
positive regulation of cellular process GO:0048522 201 0.049
tube morphogenesis GO:0035239 349 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
cytoskeleton organization GO:0007010 96 0.047
actin cytoskeleton organization GO:0030036 63 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.046
epithelial cell differentiation GO:0030855 116 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.045
digestive system development GO:0055123 289 0.045
muscle cell differentiation GO:0042692 139 0.045
nucleic acid metabolic process GO:0090304 244 0.044
hatching GO:0035188 4 0.043
regulation of response to stimulus GO:0048583 269 0.042
regulation of transcription dna templated GO:0006355 213 0.042
guanosine containing compound catabolic process GO:1901069 2 0.042
regulation of protein complex assembly GO:0043254 3 0.041
signal transduction GO:0007165 455 0.041
retinal metabolic process GO:0042574 3 0.040
striated muscle cell development GO:0055002 108 0.039
isoprenoid metabolic process GO:0006720 15 0.039
hormone transport GO:0009914 2 0.039
digestive tract morphogenesis GO:0048546 231 0.038
cellular component assembly GO:0022607 170 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
gtp catabolic process GO:0006184 2 0.037
lipid metabolic process GO:0006629 52 0.037
Mouse
regulation of biological quality GO:0065008 263 0.037
Mouse
protein metabolic process GO:0019538 183 0.036
negative regulation of gene expression GO:0010629 65 0.036
multicellular organismal response to stress GO:0033555 2 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
cell part morphogenesis GO:0032990 246 0.035
neuron differentiation GO:0030182 353 0.035
secondary metabolic process GO:0019748 3 0.035
biosynthetic process GO:0009058 294 0.035
Mouse
regulation of primary metabolic process GO:0080090 311 0.035
regulation of cell shape GO:0008360 1 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.033
cellular response to organic substance GO:0071310 105 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
transcription dna templated GO:0006351 181 0.033
striated muscle cell differentiation GO:0051146 129 0.033
organic hydroxy compound biosynthetic process GO:1901617 6 0.033
oxidation reduction process GO:0055114 41 0.032
Mouse
regulation of biosynthetic process GO:0009889 250 0.032
amine metabolic process GO:0009308 2 0.032
pectoral fin development GO:0033339 50 0.032
cellular component biogenesis GO:0044085 178 0.032
response to external biotic stimulus GO:0043207 97 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
heterocycle biosynthetic process GO:0018130 215 0.032
protein complex disassembly GO:0043241 1 0.032
positive regulation of transport GO:0051050 2 0.032
gene expression GO:0010467 252 0.031
ameboidal type cell migration GO:0001667 143 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
cellular response to estradiol stimulus GO:0071392 1 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
gland development GO:0048732 143 0.031
neuroblast proliferation GO:0007405 2 0.031
system process GO:0003008 185 0.030
protein polymerization GO:0051258 4 0.030
single fertilization GO:0007338 3 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
post embryonic organ development GO:0048569 4 0.030
positive regulation of nucleoside metabolic process GO:0045979 1 0.029
carboxylic acid metabolic process GO:0019752 22 0.029
vasculature development GO:0001944 278 0.029
regulation of gtpase activity GO:0043087 2 0.029
gtp metabolic process GO:0046039 4 0.028
blood vessel development GO:0001568 246 0.028
stem cell development GO:0048864 82 0.028
heterocycle metabolic process GO:0046483 290 0.028
regulation of signal transduction GO:0009966 225 0.028
fin morphogenesis GO:0033334 53 0.028
regulation of anatomical structure morphogenesis GO:0022603 130 0.028
positive regulation of gtp catabolic process GO:0033126 1 0.028
muscle cell development GO:0055001 115 0.028
gastrulation GO:0007369 208 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
organic heteropentacyclic compound metabolic process GO:1901376 1 0.027
positive regulation of protein complex assembly GO:0031334 2 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.026
bmp signaling pathway GO:0030509 52 0.026
vitamin biosynthetic process GO:0009110 2 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
actin polymerization or depolymerization GO:0008154 2 0.026
ether metabolic process GO:0018904 1 0.026
hemopoiesis GO:0030097 183 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
stem cell differentiation GO:0048863 117 0.026
nucleic acid templated transcription GO:0097659 181 0.026
vitamin a biosynthetic process GO:0035238 1 0.025
cellular component movement GO:0006928 335 0.025
cell migration GO:0016477 237 0.025
actomyosin structure organization GO:0031032 53 0.025
cell morphogenesis GO:0000902 289 0.025
growth GO:0040007 174 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
cellular response to starvation GO:0009267 1 0.024
appendage development GO:0048736 80 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
protein localization to nucleus GO:0034504 3 0.024
regulation of cell activation GO:0050865 1 0.024
vitamin a metabolic process GO:0006776 1 0.024
nuclear transport GO:0051169 4 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
oxoacid metabolic process GO:0043436 31 0.024
stem cell maintenance GO:0019827 4 0.024
rna biosynthetic process GO:0032774 181 0.024
aflatoxin metabolic process GO:0046222 1 0.023
stem cell proliferation GO:0072089 4 0.023
regulation of cytokine production GO:0001817 3 0.023
cellular amine metabolic process GO:0044106 2 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
organelle organization GO:0006996 227 0.023
regulation of reproductive process GO:2000241 4 0.023
heart looping GO:0001947 94 0.023
estrogen metabolic process GO:0008210 2 0.023
cellular lipid metabolic process GO:0044255 36 0.023
regulation of gene expression GO:0010468 265 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
regulation of protein depolymerization GO:1901879 1 0.022
positive regulation of leukocyte differentiation GO:1902107 1 0.022
skeletal system development GO:0001501 181 0.022
developmental growth GO:0048589 166 0.022
heart morphogenesis GO:0003007 156 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
cellular ketone metabolic process GO:0042180 11 0.022
endothelium development GO:0003158 25 0.022
regulation of protein import into nucleus GO:0042306 2 0.021
pancreas development GO:0031016 84 0.021
polyol metabolic process GO:0019751 1 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
terpenoid metabolic process GO:0006721 15 0.021
response to stress GO:0006950 263 0.021
rna metabolic process GO:0016070 219 0.021
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
neural crest cell development GO:0014032 62 0.021
positive regulation of gtpase activity GO:0043547 1 0.021
endocrine system development GO:0035270 65 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
fat soluble vitamin metabolic process GO:0006775 4 0.020
hepaticobiliary system development GO:0061008 98 0.020
endothelial cell differentiation GO:0045446 20 0.020
mycotoxin metabolic process GO:0043385 1 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
organelle assembly GO:0070925 110 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
response to alkaloid GO:0043279 2 0.019
neuron development GO:0048666 262 0.019
response to methanol GO:0033986 4 0.019
cell projection organization GO:0030030 284 0.019
sensory organ development GO:0007423 393 0.019
muscle structure development GO:0061061 196 0.019
vitamin metabolic process GO:0006766 11 0.019
regulation of protein targeting GO:1903533 2 0.019
small molecule catabolic process GO:0044282 3 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
response to carbohydrate GO:0009743 3 0.018
appendage morphogenesis GO:0035107 56 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
spermatid differentiation GO:0048515 2 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
cell cell recognition GO:0009988 1 0.018
positive regulation of secretion GO:0051047 1 0.018
interspecies interaction between organisms GO:0044419 4 0.018
regulation of protein polymerization GO:0032271 2 0.018
alcohol metabolic process GO:0006066 11 0.018
cellular response to xenobiotic stimulus GO:0071466 35 0.018
positive regulation of protein polymerization GO:0032273 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of dna replication GO:0006275 3 0.018
membrane invagination GO:0010324 1 0.018
protein import GO:0017038 3 0.018
response to bacterium GO:0009617 58 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
macromolecular complex disassembly GO:0032984 1 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.017
heart process GO:0003015 71 0.017
collagen fibril organization GO:0030199 1 0.017
locomotion GO:0040011 313 0.017
single organism biosynthetic process GO:0044711 71 0.017
Mouse
epithelial cell development GO:0002064 42 0.017
heart contraction GO:0060047 71 0.017
response to chemical GO:0042221 320 0.017
regulation of protein catabolic process GO:0042176 1 0.017
liver development GO:0001889 96 0.016
multi organism process GO:0051704 134 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
mesenchyme development GO:0060485 127 0.016
negative regulation of developmental process GO:0051093 65 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
alcohol biosynthetic process GO:0046165 2 0.016
cellular response to topologically incorrect protein GO:0035967 2 0.016
endothelial cell development GO:0001885 12 0.016
neurotransmitter secretion GO:0007269 2 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
protein depolymerization GO:0051261 1 0.016
lamellipodium organization GO:0097581 1 0.016
spindle assembly GO:0051225 2 0.016
endocrine pancreas development GO:0031018 27 0.016
viral process GO:0016032 1 0.016
regulation of cell communication GO:0010646 232 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
organic acid metabolic process GO:0006082 31 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.015
regulation of protein transport GO:0051223 3 0.015
lipid oxidation GO:0034440 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
tissue remodeling GO:0048771 4 0.015
response to vitamin GO:0033273 3 0.015
mesenchymal cell development GO:0014031 78 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of binding GO:0051098 3 0.015
aflatoxin b1 metabolic process GO:0043390 1 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of circadian rhythm GO:0042752 4 0.015
cellular response to external stimulus GO:0071496 2 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
meiotic nuclear division GO:0007126 4 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.014
small molecule biosynthetic process GO:0044283 16 0.014
regulation of localization GO:0032879 104 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
endothelial cell fate commitment GO:0060839 3 0.014
regulation of developmental process GO:0050793 247 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
response to nutrient GO:0007584 3 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
neuron projection development GO:0031175 180 0.014
response to vitamin b3 GO:0033552 2 0.014
meiotic cell cycle process GO:1903046 3 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
positive regulation of cytokine production GO:0001819 2 0.014
negative regulation of dna replication GO:0008156 2 0.014
immune system process GO:0002376 241 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
stem cell division GO:0017145 1 0.014
response to copper ion GO:0046688 13 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
actin filament organization GO:0007015 15 0.014
camera type eye development GO:0043010 222 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
synaptic vesicle localization GO:0097479 1 0.013
monoamine transport GO:0015844 1 0.013
complement activation GO:0006956 3 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
calcium ion import GO:0070509 4 0.013
negative regulation of reproductive process GO:2000242 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
response to monosaccharide GO:0034284 3 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
fertilization GO:0009566 3 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
toxin metabolic process GO:0009404 1 0.013
sensory perception of smell GO:0007608 2 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
dopamine metabolic process GO:0042417 2 0.013
positive regulation of biological process GO:0048518 253 0.013
fin development GO:0033333 77 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.012
exocrine pancreas development GO:0031017 28 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of cellular component organization GO:0051128 86 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
germ line stem cell maintenance GO:0030718 2 0.012
response to oxygen radical GO:0000305 2 0.012
endosomal transport GO:0016197 2 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
single organism nuclear import GO:1902593 3 0.012
primary alcohol metabolic process GO:0034308 7 0.012
regulation of signaling GO:0023051 235 0.012
eye morphogenesis GO:0048592 144 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
cellular response to nutrient levels GO:0031669 2 0.012
nuclear migration GO:0007097 3 0.012
b cell activation GO:0042113 2 0.012
response to glucose GO:0009749 3 0.012
acylglycerol homeostasis GO:0055090 2 0.012
lipid biosynthetic process GO:0008610 22 0.012
Mouse
positive regulation of epithelial cell migration GO:0010634 2 0.012
determination of left right symmetry GO:0007368 179 0.012
cellular protein catabolic process GO:0044257 4 0.012
mesoderm formation GO:0001707 43 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
blood vessel morphogenesis GO:0048514 216 0.012
steroid metabolic process GO:0008202 7 0.011
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
hormone secretion GO:0046879 2 0.011
response to mercury ion GO:0046689 1 0.011
microtubule organizing center organization GO:0031023 1 0.011
lymphatic endothelial cell differentiation GO:0060836 1 0.011
nuclear import GO:0051170 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
oxidative demethylation GO:0070989 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
cellular response to unfolded protein GO:0034620 2 0.011
cell motility GO:0048870 244 0.011
protein complex subunit organization GO:0071822 46 0.011
protein targeting to membrane GO:0006612 1 0.011
establishment of endothelial barrier GO:0061028 3 0.011
hormone metabolic process GO:0042445 19 0.011
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
cellular protein complex disassembly GO:0043624 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
ribonucleoside biosynthetic process GO:0042455 2 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
cell aging GO:0007569 2 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.010
endocrine hormone secretion GO:0060986 2 0.010
negative regulation of metabolic process GO:0009892 86 0.010
urogenital system development GO:0001655 97 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
negative regulation of defense response GO:0031348 2 0.010
neural crest cell differentiation GO:0014033 72 0.010
axon development GO:0061564 166 0.010
chemosensory behavior GO:0007635 1 0.010
positive regulation of catabolic process GO:0009896 4 0.010
cellular response to drug GO:0035690 1 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010
embryonic appendage morphogenesis GO:0035113 30 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
regulation of blood coagulation GO:0030193 1 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
positive regulation of cell cycle GO:0045787 3 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010

srd5a2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.015
sensory system disease DOID:0050155 0 0.012
disease of cellular proliferation DOID:14566 0 0.010