Danio rerio

0 known processes

tbl2

transducin (beta)-like 2

(Aliases: wu:fa96f08)

tbl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.073
larval development GO:0002164 2 0.071
maintenance of location GO:0051235 4 0.057
response to stress GO:0006950 263 0.057
regulation of metabolic process GO:0019222 359 0.054
nitrogen compound metabolic process GO:0006807 319 0.051
signal transduction GO:0007165 455 0.050
organic substance biosynthetic process GO:1901576 289 0.049
single organism metabolic process GO:0044710 217 0.046
cellular protein catabolic process GO:0044257 4 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.043
response to chemical GO:0042221 320 0.043
regulation of response to stimulus GO:0048583 269 0.043
positive regulation of transport GO:0051050 2 0.043
meiotic nuclear division GO:0007126 4 0.042
cellular macromolecule metabolic process GO:0044260 391 0.041
gene expression GO:0010467 252 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.040
regulation of gene expression GO:0010468 265 0.039
production of molecular mediator of immune response GO:0002440 2 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
regulation of establishment of protein localization GO:0070201 4 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.037
protein metabolic process GO:0019538 183 0.036
heterocycle metabolic process GO:0046483 290 0.036
neuron differentiation GO:0030182 353 0.035
regulation of protein transport GO:0051223 3 0.034
regulation of primary metabolic process GO:0080090 311 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
organic cyclic compound metabolic process GO:1901360 301 0.033
lipid storage GO:0019915 1 0.033
cell surface receptor signaling pathway GO:0007166 325 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
neuron development GO:0048666 262 0.031
negative regulation of biological process GO:0048519 304 0.031
regulation of biosynthetic process GO:0009889 250 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
regulation of production of molecular mediator of immune response GO:0002700 1 0.029
phagocytosis GO:0006909 3 0.029
cellular component assembly GO:0022607 170 0.029
oxoacid metabolic process GO:0043436 31 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
rna metabolic process GO:0016070 219 0.028
regulation of multicellular organismal process GO:0051239 277 0.028
nuclear transport GO:0051169 4 0.028
immune system process GO:0002376 241 0.028
multicellular organism growth GO:0035264 4 0.028
peptidyl lysine acetylation GO:0018394 2 0.028
regulation of cell activation GO:0050865 1 0.028
regulation of multicellular organism growth GO:0040014 4 0.027
biosynthetic process GO:0009058 294 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
rna biosynthetic process GO:0032774 181 0.027
regulation of cytokine production GO:0001817 3 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
single organism organelle organization GO:1902589 199 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
cognition GO:0050890 1 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
positive regulation of cell activation GO:0050867 1 0.026
leukocyte proliferation GO:0070661 1 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
amine metabolic process GO:0009308 2 0.026
organic acid metabolic process GO:0006082 31 0.026
nucleic acid templated transcription GO:0097659 181 0.026
transcription dna templated GO:0006351 181 0.026
homeostatic process GO:0042592 142 0.026
cellular amine metabolic process GO:0044106 2 0.026
tube morphogenesis GO:0035239 349 0.025
digestive tract development GO:0048565 265 0.025
cellular ketone metabolic process GO:0042180 11 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
protein acetylation GO:0006473 2 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
regulation of cell communication GO:0010646 232 0.025
regulation of biological quality GO:0065008 263 0.024
cellular component movement GO:0006928 335 0.024
regulation of rna metabolic process GO:0051252 224 0.024
positive regulation of cellular process GO:0048522 201 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
response to drug GO:0042493 3 0.024
small molecule metabolic process GO:0044281 77 0.024
generation of neurons GO:0048699 385 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
protein localization to nucleus GO:0034504 3 0.023
regulation of developmental process GO:0050793 247 0.023
cell morphogenesis GO:0000902 289 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
mononuclear cell proliferation GO:0032943 1 0.023
protein import into nucleus GO:0006606 3 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
cellular biosynthetic process GO:0044249 286 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
cellular component morphogenesis GO:0032989 336 0.023
positive regulation of catabolic process GO:0009896 4 0.023
positive regulation of biological process GO:0048518 253 0.023
cell projection organization GO:0030030 284 0.022
protein acylation GO:0043543 3 0.022
negative regulation of cellular process GO:0048523 283 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
macromolecule modification GO:0043412 111 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
cell projection morphogenesis GO:0048858 244 0.022
nucleic acid metabolic process GO:0090304 244 0.022
nuclear export GO:0051168 1 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
cellular component biogenesis GO:0044085 178 0.021
cellular protein metabolic process GO:0044267 129 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
glucose homeostasis GO:0042593 1 0.021
transport GO:0006810 220 0.021
system process GO:0003008 185 0.021
regulation of transcription dna templated GO:0006355 213 0.021
brain development GO:0007420 293 0.021
response to hexose GO:0009746 3 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
positive regulation of immune effector process GO:0002699 3 0.021
autophagy GO:0006914 4 0.021
response to monosaccharide GO:0034284 3 0.021
response to external stimulus GO:0009605 264 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
meiotic cell cycle process GO:1903046 3 0.021
cellular protein modification process GO:0006464 100 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
regulation of rna biosynthetic process GO:2001141 213 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
establishment of localization GO:0051234 244 0.020
mitochondrion organization GO:0007005 4 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
single organism nuclear import GO:1902593 3 0.020
small molecule catabolic process GO:0044282 3 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
organelle organization GO:0006996 227 0.020
cellular response to external stimulus GO:0071496 2 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
gtp metabolic process GO:0046039 4 0.020
cellular amide metabolic process GO:0043603 4 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
regulation of inflammatory response GO:0050727 2 0.019
female sex differentiation GO:0046660 4 0.019
gtp catabolic process GO:0006184 2 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
cytokinesis GO:0000910 3 0.019
response to organic substance GO:0010033 153 0.019
lymphocyte proliferation GO:0046651 1 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
regulation of metal ion transport GO:0010959 4 0.019
head development GO:0060322 303 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of signal transduction GO:0009966 225 0.019
heart development GO:0007507 313 0.019
localization of cell GO:0051674 244 0.018
stem cell proliferation GO:0072089 4 0.018
central nervous system development GO:0007417 387 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of signaling GO:0023051 235 0.018
positive regulation of cell cycle GO:0045787 3 0.018
embryonic organ development GO:0048568 381 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
toll like receptor signaling pathway GO:0002224 4 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
positive regulation of cytokine production GO:0001819 2 0.017
gastrulation GO:0007369 208 0.017
cell part morphogenesis GO:0032990 246 0.017
protein import GO:0017038 3 0.017
single organism localization GO:1902578 225 0.017
positive regulation of secretion GO:0051047 1 0.017
tissue remodeling GO:0048771 4 0.017
regulation of dna replication GO:0006275 3 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
spermatid development GO:0007286 2 0.016
interspecies interaction between organisms GO:0044419 4 0.016
digestive system development GO:0055123 289 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
cell substrate adhesion GO:0031589 4 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
cell adhesion GO:0007155 40 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
antimicrobial humoral response GO:0019730 2 0.016
nuclear import GO:0051170 3 0.016
growth GO:0040007 174 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
neuron projection morphogenesis GO:0048812 161 0.016
regulation of protein catabolic process GO:0042176 1 0.015
sensory organ development GO:0007423 393 0.015
protein modification process GO:0036211 100 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
negative regulation of cytokine production GO:0001818 1 0.015
regulation of calcium ion transport GO:0051924 2 0.015
response to nutrient GO:0007584 3 0.015
response to endogenous stimulus GO:0009719 83 0.015
female gonad development GO:0008585 4 0.015
adherens junction organization GO:0034332 4 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
response to corticosteroid GO:0031960 1 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
regulation of protein targeting GO:1903533 2 0.015
peptidyl serine modification GO:0018209 2 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
lipid homeostasis GO:0055088 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
stem cell maintenance GO:0019827 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.014
locomotion GO:0040011 313 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
fertilization GO:0009566 3 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of chromosome segregation GO:0051983 1 0.014
peptide metabolic process GO:0006518 1 0.014
phagocytosis engulfment GO:0006911 1 0.014
response to glucose GO:0009749 3 0.014
cellular response to organic substance GO:0071310 105 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
camera type eye development GO:0043010 222 0.014
regulation of reproductive process GO:2000241 4 0.014
regulation of cell shape GO:0008360 1 0.014
blood vessel development GO:0001568 246 0.014
regulation of blood pressure GO:0008217 1 0.014
single organism transport GO:0044765 206 0.014
cell migration GO:0016477 237 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
sequestering of metal ion GO:0051238 3 0.014
eye development GO:0001654 277 0.014
vasculature development GO:0001944 278 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
phosphorus metabolic process GO:0006793 109 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
immune system development GO:0002520 191 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
response to carbohydrate GO:0009743 3 0.013
response to wounding GO:0009611 116 0.013
cellular response to nutrient levels GO:0031669 2 0.013
carbohydrate homeostasis GO:0033500 1 0.013
negative regulation of nuclear division GO:0051784 3 0.013
negative regulation of catabolic process GO:0009895 3 0.013
protein targeting to nucleus GO:0044744 3 0.013
response to glucocorticoid GO:0051384 1 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
protein secretion GO:0009306 1 0.013
cell motility GO:0048870 244 0.013
sequestering of calcium ion GO:0051208 3 0.013
rna localization GO:0006403 4 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
protein stabilization GO:0050821 2 0.013
peptide transport GO:0015833 1 0.013
negative regulation of defense response GO:0031348 2 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
defense response GO:0006952 47 0.013
digestive tract morphogenesis GO:0048546 231 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
negative regulation of secretion GO:0051048 2 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
regulation of receptor activity GO:0010469 2 0.013
negative regulation of protein transport GO:0051224 3 0.013
regulation of synapse assembly GO:0051963 3 0.013
carboxylic acid catabolic process GO:0046395 3 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
microtubule organizing center organization GO:0031023 1 0.013
response to external biotic stimulus GO:0043207 97 0.013
phosphorylation GO:0016310 69 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
positive regulation of histone modification GO:0031058 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
protein localization to plasma membrane GO:0072659 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
negative regulation of metabolic process GO:0009892 86 0.012
membrane invagination GO:0010324 1 0.012
regulation of protein metabolic process GO:0051246 56 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
response to alkaloid GO:0043279 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of synapse organization GO:0050807 3 0.012
hormone secretion GO:0046879 2 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of protein complex assembly GO:0043254 3 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
muscle tissue development GO:0060537 110 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
secondary metabolic process GO:0019748 3 0.012
neuron projection development GO:0031175 180 0.012
meiotic chromosome segregation GO:0045132 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of cellular component organization GO:0051128 86 0.012
response to other organism GO:0051707 97 0.012
organelle assembly GO:0070925 110 0.012
cytokinetic process GO:0032506 2 0.012
blood vessel morphogenesis GO:0048514 216 0.012
double strand break repair GO:0006302 3 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
chordate embryonic development GO:0043009 271 0.012
neuroblast proliferation GO:0007405 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
multi organism process GO:0051704 134 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of binding GO:0051098 3 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of hormone secretion GO:0046883 2 0.011
response to lipid GO:0033993 60 0.011
developmental growth GO:0048589 166 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
single fertilization GO:0007338 3 0.011
negative regulation of gene expression GO:0010629 65 0.011
negative regulation of developmental process GO:0051093 65 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
positive regulation of metabolic process GO:0009893 108 0.011
response to abiotic stimulus GO:0009628 122 0.011
cellular localization GO:0051641 97 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
hemopoiesis GO:0030097 183 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
specification of symmetry GO:0009799 204 0.011
ovulation cycle GO:0042698 2 0.011
response to ketone GO:1901654 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
positive regulation of translation GO:0045727 1 0.011
determination of left right symmetry GO:0007368 179 0.011
endosomal transport GO:0016197 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
cell matrix adhesion GO:0007160 4 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
regulation of localization GO:0032879 104 0.010
cellular response to oxygen levels GO:0071453 1 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
single organism membrane fusion GO:0044801 2 0.010
transmembrane transport GO:0055085 120 0.010
locomotor rhythm GO:0045475 3 0.010
angiogenesis GO:0001525 158 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of response to external stimulus GO:0032101 31 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
regulation of molecular function GO:0065009 70 0.010
germ line stem cell maintenance GO:0030718 2 0.010
gland development GO:0048732 143 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
protein homooligomerization GO:0051260 3 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010

tbl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
musculoskeletal system disease DOID:17 0 0.027
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.018
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
myopathy DOID:423 0 0.013
inherited metabolic disorder DOID:655 0 0.011