Danio rerio

0 known processes

atp1a1a.4

ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide

(Aliases: atp1a1l4,cb708,atp[a]1A1)

atp1a1a.4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular sodium ion homeostasis GO:0006883 1 0.982
Human
monovalent inorganic cation transport GO:0015672 42 0.975
Human Zebrafish Mouse Rat Worm Fly
metal ion transport GO:0030001 58 0.945
Human Zebrafish Mouse Rat Worm Fly
establishment of localization GO:0051234 244 0.897
Human Zebrafish Mouse Rat Worm Fly
tube morphogenesis GO:0035239 349 0.881
Zebrafish
ion transport GO:0006811 114 0.813
Human Zebrafish Mouse Rat Worm Fly
cation transmembrane transport GO:0098655 65 0.793
Human Zebrafish Mouse Rat Worm Fly
fluid transport GO:0042044 17 0.787
Zebrafish
ion transmembrane transport GO:0034220 91 0.783
Human Zebrafish Mouse Rat Worm Fly
regulation of metal ion transport GO:0010959 4 0.750
Rat
inorganic cation transmembrane transport GO:0098662 50 0.742
Human Zebrafish Mouse Rat Worm Fly
heart development GO:0007507 313 0.722
Zebrafish
single organism localization GO:1902578 225 0.718
Human Zebrafish Mouse Rat Worm Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.699
Human Zebrafish Mouse Rat Worm Fly
regulation of sodium ion transport GO:0002028 2 0.656
Rat
transmembrane transport GO:0055085 120 0.620
Human Zebrafish Mouse Rat Worm Fly
pigmentation GO:0043473 85 0.619
potassium ion transport GO:0006813 10 0.595
Human Zebrafish Mouse Rat Worm Fly
single organism transport GO:0044765 206 0.576
Human Zebrafish Mouse Rat Worm Fly
regulation of cardiac muscle cell contraction GO:0086004 1 0.573
Rat
transport GO:0006810 220 0.546
Human Zebrafish Mouse Rat Worm Fly
glucocorticoid metabolic process GO:0008211 2 0.519
Mouse
regulation of metabolic process GO:0019222 359 0.498
Mouse
membrane repolarization GO:0086009 2 0.486
Human
sodium ion transport GO:0006814 24 0.480
Human Zebrafish Mouse Rat Worm Fly
embryonic heart tube development GO:0035050 133 0.475
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.473
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.473
Human Zebrafish Mouse Rat Worm Fly
regionalization GO:0003002 274 0.468
Zebrafish
central nervous system development GO:0007417 387 0.457
Zebrafish
inorganic ion transmembrane transport GO:0098660 57 0.456
Human Zebrafish Mouse Rat Worm Fly
digestive system development GO:0055123 289 0.451
regulation of muscle contraction GO:0006937 3 0.445
Mouse Rat Worm
cardiac muscle cell contraction GO:0086003 1 0.441
Rat
embryonic organ morphogenesis GO:0048562 274 0.427
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.364
Human Zebrafish Mouse Rat Worm Fly
reproduction GO:0000003 40 0.352
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.344
Zebrafish Worm Fly
digestive tract development GO:0048565 265 0.317
membrane hyperpolarization GO:0060081 1 0.317
Rat
embryonic heart tube morphogenesis GO:0003143 108 0.314
Zebrafish
determination of left right symmetry GO:0007368 179 0.314
Zebrafish
atp catabolic process GO:0006200 4 0.300
Human Zebrafish Mouse Rat Worm Fly
sensory system development GO:0048880 76 0.295
positive regulation of biological process GO:0048518 253 0.283
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.273
Human Zebrafish Mouse Rat Worm Fly
regulation of localization GO:0032879 104 0.273
Rat
regulation of ion transport GO:0043269 22 0.265
Rat
embryonic organ development GO:0048568 381 0.263
Zebrafish
larval development GO:0002164 2 0.251
Worm
maintenance of location GO:0051235 4 0.250
cellular potassium ion transport GO:0071804 10 0.248
Human Zebrafish Mouse Rat Worm Fly
regulation of cardiac muscle contraction GO:0055117 2 0.248
Rat
locomotion GO:0040011 313 0.240
Zebrafish
small molecule metabolic process GO:0044281 77 0.229
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.228
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.224
Human Zebrafish Mouse Rat Worm Fly
regulation of transport GO:0051049 45 0.224
Rat
biosynthetic process GO:0009058 294 0.222
Mouse
ear development GO:0043583 127 0.222
Zebrafish
aging GO:0007568 2 0.218
Fly
sensory organ development GO:0007423 393 0.209
Zebrafish
regulation of actin filament based movement GO:1903115 1 0.208
Rat
digestive tract morphogenesis GO:0048546 231 0.205
lipid storage GO:0019915 1 0.201
actin filament based movement GO:0030048 1 0.196
Rat
cation transport GO:0006812 81 0.195
Human Zebrafish Mouse Rat Worm Fly
regulation of membrane potential GO:0042391 23 0.193
Human Rat Worm
muscle contraction GO:0006936 18 0.191
Mouse Rat Worm
determination of bilateral symmetry GO:0009855 204 0.188
Zebrafish
head development GO:0060322 303 0.184
Zebrafish
regulation of biological quality GO:0065008 263 0.183
Human Zebrafish Mouse Rat Worm Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.178
Human Zebrafish Mouse Rat Worm Fly
adherens junction maintenance GO:0034334 2 0.178
gastrulation GO:0007369 208 0.176
epithelial tube morphogenesis GO:0060562 148 0.174
Zebrafish
heart looping GO:0001947 94 0.173
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.169
determination of heart left right asymmetry GO:0061371 117 0.168
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.162
Zebrafish
regulation of cell shape GO:0008360 1 0.157
Fly
lateral line system development GO:0048925 76 0.155
skeletal muscle organ development GO:0060538 78 0.155
Zebrafish
otolith development GO:0048840 32 0.152
Zebrafish
specification of symmetry GO:0009799 204 0.149
Zebrafish
hormone biosynthetic process GO:0042446 3 0.149
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.144
Fly
oligopeptide transport GO:0006857 1 0.144
regulation of cell communication GO:0010646 232 0.141
cell morphogenesis GO:0000902 289 0.139
Fly
alpha amino acid metabolic process GO:1901605 3 0.138
cardiocyte differentiation GO:0035051 44 0.136
Zebrafish
response to drug GO:0042493 3 0.136
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.135
Human Zebrafish Mouse Rat Worm Fly
axial mesoderm morphogenesis GO:0048319 8 0.126
response to organic cyclic compound GO:0014070 51 0.126
Human
defense response GO:0006952 47 0.125
actin mediated cell contraction GO:0070252 1 0.125
Rat
brain development GO:0007420 293 0.124
Zebrafish
neural tube development GO:0021915 62 0.122
Zebrafish
cellular component assembly GO:0022607 170 0.121
Fly
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.121
Human
somite development GO:0061053 96 0.120
localization of cell GO:0051674 244 0.120
Zebrafish
lipid catabolic process GO:0016042 4 0.109
regulation of intracellular signal transduction GO:1902531 57 0.108
macromolecule biosynthetic process GO:0009059 227 0.107
skeletal system development GO:0001501 181 0.107
cellular component movement GO:0006928 335 0.104
Zebrafish Rat
heart morphogenesis GO:0003007 156 0.103
Zebrafish
response to stress GO:0006950 263 0.103
purine containing compound metabolic process GO:0072521 29 0.102
Human Zebrafish Mouse Rat Worm Fly
organonitrogen compound metabolic process GO:1901564 74 0.101
Human Zebrafish Mouse Rat Worm Fly
otic vesicle development GO:0071599 42 0.100
Zebrafish
somitogenesis GO:0001756 87 0.098
chordate embryonic development GO:0043009 271 0.095
Zebrafish
anion transmembrane transport GO:0098656 12 0.094
heterocycle metabolic process GO:0046483 290 0.091
Human Zebrafish Mouse Rat Worm Fly
positive regulation of metabolic process GO:0009893 108 0.090
negative regulation of heart contraction GO:0045822 2 0.089
Mouse
response to nutrient GO:0007584 3 0.089
multicellular organism growth GO:0035264 4 0.088
response to lipid GO:0033993 60 0.088
Human
neuromast development GO:0048884 46 0.087
positive regulation of cellular process GO:0048522 201 0.087
muscle structure development GO:0061061 196 0.087
Zebrafish
regulation of gene expression GO:0010468 265 0.087
otic vesicle formation GO:0030916 27 0.087
Zebrafish
angiogenesis GO:0001525 158 0.086
regulation of macromolecule biosynthetic process GO:0010556 225 0.083
retina morphogenesis in camera type eye GO:0060042 79 0.082
adherens junction organization GO:0034332 4 0.082
sodium ion transmembrane transport GO:0035725 21 0.081
Human Zebrafish Mouse Rat Worm Fly
eye development GO:0001654 277 0.081
organic acid metabolic process GO:0006082 31 0.080
regulation of multicellular organism growth GO:0040014 4 0.080
sensory organ morphogenesis GO:0090596 200 0.078
Zebrafish
regulation of transmembrane transport GO:0034762 18 0.077
lateral line development GO:0048882 66 0.076
multi organism reproductive process GO:0044703 36 0.076
potassium ion transmembrane transport GO:0071805 10 0.076
Human Zebrafish Mouse Rat Worm Fly
cellular response to external stimulus GO:0071496 2 0.075
Rat
regulation of primary metabolic process GO:0080090 311 0.075
Mouse
positive regulation of cell adhesion GO:0045785 1 0.074
stem cell differentiation GO:0048863 117 0.073
cellular nitrogen compound metabolic process GO:0034641 290 0.073
Human Zebrafish Mouse Rat Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.072
cellular component maintenance GO:0043954 3 0.072
neural crest cell differentiation GO:0014033 72 0.071
muscle system process GO:0003012 20 0.070
Mouse Rat Worm
immune system process GO:0002376 241 0.069
heterocycle catabolic process GO:0046700 15 0.069
Human Zebrafish Mouse Rat Worm Fly
cell projection organization GO:0030030 284 0.069
muscle tissue development GO:0060537 110 0.069
Zebrafish
single organism metabolic process GO:0044710 217 0.068
Human Zebrafish Mouse Rat Worm Fly
ameboidal type cell migration GO:0001667 143 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.067
homeostatic process GO:0042592 142 0.066
Human Zebrafish Fly
negative regulation of cellular process GO:0048523 283 0.066
Mouse
multi organism process GO:0051704 134 0.065
nitrogen compound metabolic process GO:0006807 319 0.065
Human Zebrafish Mouse Rat Worm Fly
carboxylic acid metabolic process GO:0019752 22 0.065
carbohydrate derivative metabolic process GO:1901135 61 0.064
Human Zebrafish Mouse Rat Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.063
Mouse Rat Worm
negative regulation of biological process GO:0048519 304 0.062
Mouse
cartilage development GO:0051216 96 0.061
cell migration involved in heart development GO:0060973 22 0.061
Zebrafish
response to steroid hormone GO:0048545 35 0.061
Human
mesoderm morphogenesis GO:0048332 51 0.061
sodium ion homeostasis GO:0055078 3 0.060
Human
cell motility GO:0048870 244 0.058
Zebrafish
cellular response to organic cyclic compound GO:0071407 38 0.058
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.057
lipid digestion GO:0044241 3 0.057
aromatic compound biosynthetic process GO:0019438 217 0.057
intestinal absorption GO:0050892 2 0.056
mesoderm development GO:0007498 88 0.056
positive regulation of map kinase activity GO:0043406 3 0.056
positive regulation of transport GO:0051050 2 0.055
regulation of cellular biosynthetic process GO:0031326 245 0.055
Mouse
developmental pigmentation GO:0048066 48 0.054
axis elongation involved in somitogenesis GO:0090245 2 0.054
ion homeostasis GO:0050801 41 0.053
Human Zebrafish
pectoral fin development GO:0033339 50 0.053
system process GO:0003008 185 0.053
Zebrafish Mouse Rat Worm Fly
regulation of ion transmembrane transporter activity GO:0032412 2 0.052
cellular component morphogenesis GO:0032989 336 0.051
Fly
regulation of striated muscle contraction GO:0006942 2 0.051
Mouse Rat
developmental growth GO:0048589 166 0.050
Fly
gland development GO:0048732 143 0.050
cell migration involved in heart formation GO:0060974 10 0.050
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.050
Human Zebrafish Mouse Rat Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.049
inner ear development GO:0048839 126 0.049
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.048
blood circulation GO:0008015 87 0.048
Zebrafish Mouse Rat
skeletal muscle tissue development GO:0007519 67 0.047
Zebrafish
thigmotaxis GO:0001966 5 0.046
Zebrafish
peptide transport GO:0015833 1 0.046
epithelial cell differentiation GO:0030855 116 0.046
regulation of multicellular organismal development GO:2000026 223 0.045
cellular lipid metabolic process GO:0044255 36 0.045
positive regulation of catabolic process GO:0009896 4 0.045
atp metabolic process GO:0046034 5 0.045
Human Zebrafish Mouse Rat Worm Fly
cellular component biogenesis GO:0044085 178 0.044
Fly
cell cell junction assembly GO:0007043 5 0.044
Fly
monovalent inorganic cation homeostasis GO:0055067 9 0.044
Human
otic vesicle morphogenesis GO:0071600 34 0.044
Zebrafish
negative regulation of blood circulation GO:1903523 2 0.043
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.043
Fly
signal transduction GO:0007165 455 0.043
establishment of epithelial cell apical basal polarity GO:0045198 2 0.042
regulation of cell differentiation GO:0045595 142 0.042
cellular response to lipid GO:0071396 39 0.042
Human
ribose phosphate metabolic process GO:0019693 27 0.042
Human Zebrafish Mouse Rat Worm Fly
specification of axis polarity GO:0065001 4 0.042
Zebrafish
startle response GO:0001964 4 0.042
response to abiotic stimulus GO:0009628 122 0.042
Rat Fly
intracellular signal transduction GO:0035556 85 0.041
regulation of photoreceptor cell differentiation GO:0046532 2 0.041
oxoacid metabolic process GO:0043436 31 0.041
gene expression GO:0010467 252 0.040
organic substance transport GO:0071702 58 0.040
growth GO:0040007 174 0.039
Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.039
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.039
neural tube patterning GO:0021532 33 0.039
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.038
positive regulation of cellular metabolic process GO:0031325 94 0.038
multicellular organism reproduction GO:0032504 35 0.038
semicircular canal morphogenesis GO:0048752 18 0.038
Zebrafish
protein localization to plasma membrane GO:0072659 1 0.037
cellular response to steroid hormone stimulus GO:0071383 31 0.036
Human
regulation of system process GO:0044057 40 0.036
Mouse Rat Worm
water homeostasis GO:0030104 4 0.036
respiratory system development GO:0060541 5 0.036
Fly
regulation of cellular component movement GO:0051270 55 0.036
Rat
sensory perception of mechanical stimulus GO:0050954 16 0.036
Fly
alcohol biosynthetic process GO:0046165 2 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
calcium ion homeostasis GO:0055074 19 0.035
Zebrafish
regulation of eye photoreceptor cell development GO:0042478 2 0.035
dicarboxylic acid metabolic process GO:0043648 1 0.035
gamete generation GO:0007276 33 0.035
heart process GO:0003015 71 0.035
Zebrafish Mouse Rat
macromolecule localization GO:0033036 54 0.034
cellular localization GO:0051641 97 0.034
erythrocyte homeostasis GO:0034101 55 0.034
striated muscle contraction GO:0006941 12 0.034
Mouse Rat
regulation of nucleoside metabolic process GO:0009118 2 0.034
neuron differentiation GO:0030182 353 0.034
inner ear receptor stereocilium organization GO:0060122 8 0.034
response to monosaccharide GO:0034284 3 0.033
actin polymerization or depolymerization GO:0008154 2 0.033
camera type eye morphogenesis GO:0048593 108 0.033
carbon dioxide transport GO:0015670 3 0.033
chemical homeostasis GO:0048878 49 0.033
Human Zebrafish
response to external stimulus GO:0009605 264 0.033
Zebrafish Rat Fly
aromatic compound catabolic process GO:0019439 15 0.033
Human Zebrafish Mouse Rat Worm Fly
regulation of transmembrane transporter activity GO:0022898 2 0.032
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.032
heart contraction GO:0060047 71 0.032
Zebrafish Mouse Rat
establishment of epithelial cell polarity GO:0090162 2 0.032
regulation of ion transmembrane transport GO:0034765 18 0.032
generation of neurons GO:0048699 385 0.032
cellular nitrogen compound catabolic process GO:0044270 15 0.032
Human Zebrafish Mouse Rat Worm Fly
muscle organ development GO:0007517 101 0.032
Zebrafish
inner ear morphogenesis GO:0042472 63 0.032
Zebrafish
intestinal cholesterol absorption GO:0030299 2 0.031
photoreceptor cell fate specification GO:0043704 1 0.031
amine metabolic process GO:0009308 2 0.031
lipid homeostasis GO:0055088 3 0.031
olfactory bulb development GO:0021772 4 0.031
regulation of biosynthetic process GO:0009889 250 0.031
Mouse
nucleoside phosphate metabolic process GO:0006753 28 0.031
Human Zebrafish Mouse Rat Worm Fly
neuron development GO:0048666 262 0.031
cellular response to chemical stimulus GO:0070887 157 0.030
Human
regulation of transporter activity GO:0032409 2 0.030
regulation of blood pressure GO:0008217 1 0.030
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
cell cell junction organization GO:0045216 10 0.030
Fly
cartilage condensation GO:0001502 3 0.030
glucocorticoid biosynthetic process GO:0006704 1 0.030
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.030
Mouse
ribonucleoside metabolic process GO:0009119 11 0.029
Human Zebrafish Mouse Rat Worm Fly
response to glucocorticoid GO:0051384 1 0.029
segmentation GO:0035282 97 0.029
blood vessel morphogenesis GO:0048514 216 0.029
mesenchymal cell development GO:0014031 78 0.029
cellular modified amino acid metabolic process GO:0006575 3 0.029
exocrine system development GO:0035272 28 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
lipid biosynthetic process GO:0008610 22 0.028
Mouse
regulation of hormone metabolic process GO:0032350 6 0.028
Mouse
lipid metabolic process GO:0006629 52 0.027
Mouse
regulation of locomotion GO:0040012 55 0.027
regulation of calcium ion transport GO:0051924 2 0.027
cellular response to organic substance GO:0071310 105 0.027
Human
response to vitamin b3 GO:0033552 2 0.026
inorganic anion transmembrane transport GO:0098661 10 0.026
striated muscle tissue development GO:0014706 110 0.026
Zebrafish
midbrain hindbrain boundary development GO:0030917 23 0.026
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.026
response to hexose GO:0009746 3 0.026
nucleobase containing compound catabolic process GO:0034655 15 0.026
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
neurological system process GO:0050877 62 0.026
Fly
regulation of heart contraction GO:0008016 32 0.026
Mouse Rat
positive regulation of transcription dna templated GO:0045893 57 0.026
cell aggregation GO:0098743 3 0.025
regulation of cellular component organization GO:0051128 86 0.025
Fly
myeloid leukocyte differentiation GO:0002573 15 0.025
positive regulation of response to stimulus GO:0048584 80 0.025
regulation of stem cell differentiation GO:2000736 4 0.025
cellular amine metabolic process GO:0044106 2 0.024
gastrulation with mouth forming second GO:0001702 44 0.024
olfactory lobe development GO:0021988 4 0.024
connective tissue development GO:0061448 99 0.024
hormone metabolic process GO:0042445 19 0.024
Mouse
secondary metabolic process GO:0019748 3 0.024
regulation of signaling GO:0023051 235 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
female sex differentiation GO:0046660 4 0.024
response to chemical GO:0042221 320 0.024
Human Mouse
mesenchyme development GO:0060485 127 0.024
action potential GO:0001508 19 0.024
Worm
response to organic substance GO:0010033 153 0.024
Human
transcription dna templated GO:0006351 181 0.024
semicircular canal development GO:0060872 24 0.024
Zebrafish
peripheral nervous system development GO:0007422 55 0.024
digestive tract mesoderm development GO:0007502 1 0.023
circulatory system process GO:0003013 87 0.023
Zebrafish Mouse Rat
taxis GO:0042330 109 0.023
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.023
axial mesoderm development GO:0048318 10 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
gas transport GO:0015669 3 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
pancreas development GO:0031016 84 0.023
positive regulation of nucleotide catabolic process GO:0030813 1 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
septum transversum development GO:0003343 4 0.022
polarized epithelial cell differentiation GO:0030859 4 0.022
nucleobase containing small molecule metabolic process GO:0055086 32 0.022
Human Zebrafish Mouse Rat Worm Fly
cellular response to nutrient levels GO:0031669 2 0.022
cell cell adhesion involved in gastrulation GO:0070586 4 0.022
cellular ion homeostasis GO:0006873 17 0.022
Human Zebrafish
lipid localization GO:0010876 11 0.022
response to endogenous stimulus GO:0009719 83 0.022
Human
chloride transport GO:0006821 8 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.022
Human Zebrafish Mouse Rat Worm Fly
nitrogen compound transport GO:0071705 23 0.022
protein localization to nucleus GO:0034504 3 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.021
erythrocyte differentiation GO:0030218 54 0.021
cell migration involved in gastrulation GO:0042074 79 0.021
ectoderm development GO:0007398 9 0.021
cellular response to hormone stimulus GO:0032870 39 0.021
Human
nucleic acid metabolic process GO:0090304 244 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
tube formation GO:0035148 25 0.021
regulation of molecular function GO:0065009 70 0.021
hair cell differentiation GO:0035315 32 0.021
cell surface receptor signaling pathway GO:0007166 325 0.020
regulation of bone remodeling GO:0046850 2 0.020
single organism nuclear import GO:1902593 3 0.020
cerebellum formation GO:0021588 2 0.020
pectoral fin morphogenesis GO:0035138 29 0.020
oxidative demethylation GO:0070989 1 0.020
behavior GO:0007610 74 0.020
Zebrafish Fly
phosphorus metabolic process GO:0006793 109 0.020
Human Zebrafish Mouse Rat Worm Fly
multicellular organismal reproductive process GO:0048609 35 0.020
fin development GO:0033333 77 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
photoreceptor cell fate commitment GO:0046552 1 0.020
appendage development GO:0048736 80 0.020
neural crest cell migration GO:0001755 42 0.020
nucleotide metabolic process GO:0009117 28 0.020
Human Zebrafish Mouse Rat Worm Fly
cardiac muscle contraction GO:0060048 6 0.020
Rat
cellular response to endogenous stimulus GO:0071495 68 0.020
Human
neuron recognition GO:0008038 18 0.019
cell junction maintenance GO:0034331 2 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.019
ventricular system development GO:0021591 12 0.019
Zebrafish
organic cyclic compound catabolic process GO:1901361 15 0.019
Human Zebrafish Mouse Rat Worm Fly
response to hormone GO:0009725 48 0.019
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.019
regulation of protein complex assembly GO:0043254 3 0.019
cellular divalent inorganic cation homeostasis GO:0072503 13 0.019
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.019
midbrain development GO:0030901 28 0.019
neuromuscular process GO:0050905 7 0.019
Fly
cellular biosynthetic process GO:0044249 286 0.019
Mouse
regulation of developmental process GO:0050793 247 0.018
Fly
myeloid cell homeostasis GO:0002262 56 0.018
regulation of skeletal muscle tissue development GO:0048641 4 0.018
auditory receptor cell morphogenesis GO:0002093 4 0.018
regulation of cell activation GO:0050865 1 0.018
response to cadmium ion GO:0046686 14 0.018
chloride transmembrane transport GO:1902476 4 0.018
regulation of sodium ion transmembrane transport GO:1902305 1 0.018
neuron projection development GO:0031175 180 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
Mouse
pigment cell differentiation GO:0050931 38 0.018
organic hydroxy compound transport GO:0015850 14 0.018
multicellular organismal homeostasis GO:0048871 29 0.018
Fly
cranial nerve development GO:0021545 42 0.017
response to food GO:0032094 1 0.017
mesendoderm development GO:0048382 10 0.017
endosomal transport GO:0016197 2 0.017
negative regulation of kinase activity GO:0033673 4 0.017
eye morphogenesis GO:0048592 144 0.017
inner ear receptor cell differentiation GO:0060113 29 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
Mouse
amide transport GO:0042886 12 0.017
neural crest cell development GO:0014032 62 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of cytokine production GO:0001817 3 0.016
branched chain amino acid metabolic process GO:0009081 1 0.016
response to corticosteroid GO:0031960 1 0.016
positive regulation of cell differentiation GO:0045597 30 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
endothelial cell development GO:0001885 12 0.016
nucleoside metabolic process GO:0009116 11 0.016
Human Zebrafish Mouse Rat Worm Fly
isoprenoid biosynthetic process GO:0008299 7 0.016
positive regulation of muscle organ development GO:0048636 1 0.016
cell cell signaling GO:0007267 52 0.016
Fly
protein stabilization GO:0050821 2 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
cellular chemical homeostasis GO:0055082 17 0.016
Human Zebrafish
cell migration involved in mesendoderm migration GO:0090134 2 0.016
positive regulation of molecular function GO:0044093 33 0.016
regulation of cell death GO:0010941 103 0.016
purine nucleoside monophosphate metabolic process GO:0009126 5 0.016
Human Zebrafish Mouse Rat Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
protein metabolic process GO:0019538 183 0.016
Worm
catecholamine biosynthetic process GO:0042423 2 0.016
organic substance biosynthetic process GO:1901576 289 0.015
Mouse
regulation of developmental growth GO:0048638 38 0.015
regulation of reproductive process GO:2000241 4 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
somatic muscle development GO:0007525 4 0.015
ammonium transmembrane transport GO:0072488 2 0.015
determination of dorsal ventral asymmetry GO:0048262 34 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
endoderm development GO:0007492 49 0.015
gtp catabolic process GO:0006184 2 0.015
response to vitamin GO:0033273 3 0.015
appendage morphogenesis GO:0035107 56 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
pigment cell development GO:0070285 3 0.015
nitric oxide biosynthetic process GO:0006809 2 0.015
bone morphogenesis GO:0060349 11 0.015
mechanoreceptor differentiation GO:0042490 37 0.015
medial fin morphogenesis GO:0035141 14 0.014
sexual reproduction GO:0019953 36 0.014
catabolic process GO:0009056 32 0.014
Human Zebrafish Mouse Rat Worm Fly
cardiac muscle cell differentiation GO:0055007 30 0.014
b cell activation GO:0042113 2 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
rna metabolic process GO:0016070 219 0.014
camera type eye development GO:0043010 222 0.014
one carbon compound transport GO:0019755 14 0.014
primitive hemopoiesis GO:0060215 27 0.014
stem cell development GO:0048864 82 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cell junction organization GO:0034330 11 0.014
Fly
cellular response to hypoxia GO:0071456 1 0.014
myelin assembly GO:0032288 1 0.014
mesendoderm migration GO:0090133 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.014
activation of mapk activity GO:0000187 3 0.014
regulation of neurogenesis GO:0050767 87 0.014
endocardial cushion formation GO:0003272 2 0.014
regulation of protein polymerization GO:0032271 2 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of hormone levels GO:0010817 21 0.013
Mouse
positive regulation of heart contraction GO:0045823 2 0.013
Mouse
axis specification GO:0009798 43 0.013
Zebrafish
regulation of blood vessel size GO:0050880 2 0.013
regulation of hormone secretion GO:0046883 2 0.013
response to nutrient levels GO:0031667 10 0.013

atp1a1a.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.229
musculoskeletal system disease DOID:17 0 0.101
muscular disease DOID:0080000 0 0.057
cardiovascular system disease DOID:1287 0 0.051
myopathy DOID:423 0 0.037
heart disease DOID:114 0 0.037
cardiomyopathy DOID:0050700 0 0.037
muscle tissue disease DOID:66 0 0.037
nervous system disease DOID:863 0 0.036
disease of metabolism DOID:0014667 0 0.023
intrinsic cardiomyopathy DOID:0060036 0 0.019