Danio rerio

26 known processes

atp1a1a.2

ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide

(Aliases: cb703,atp[a]1A2b,zgc:110523,atp1a1l2)

atp1a1a.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of heart contraction GO:0045822 2 0.974
Mouse
regulation of sodium ion transport GO:0002028 2 0.970
Rat
otic vesicle formation GO:0030916 27 0.958
Zebrafish
cellular potassium ion transport GO:0071804 10 0.953
Human Zebrafish Mouse Rat Worm Fly
otic vesicle development GO:0071599 42 0.917
Zebrafish
ear development GO:0043583 127 0.883
ear morphogenesis GO:0042471 64 0.855
sensory organ development GO:0007423 393 0.805
sodium ion transport GO:0006814 24 0.799
Human Zebrafish Mouse Rat Worm Fly
sensory organ morphogenesis GO:0090596 200 0.798
otolith development GO:0048840 32 0.791
Zebrafish
monovalent inorganic cation homeostasis GO:0055067 9 0.771
Human
otic vesicle morphogenesis GO:0071600 34 0.761
Zebrafish
semicircular canal development GO:0060872 24 0.742
specification of axis polarity GO:0065001 4 0.712
Zebrafish
inorganic ion transmembrane transport GO:0098660 57 0.691
Human Zebrafish Mouse Rat Worm Fly
larval development GO:0002164 2 0.686
Worm
cellular sodium ion homeostasis GO:0006883 1 0.679
Human
midbrain hindbrain boundary development GO:0030917 23 0.665
Zebrafish
negative regulation of blood circulation GO:1903523 2 0.628
Mouse
inner ear development GO:0048839 126 0.590
regulation of actin filament based movement GO:1903115 1 0.588
Rat
potassium ion transport GO:0006813 10 0.579
Human Zebrafish Mouse Rat Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.579
Human Zebrafish Mouse Rat Worm Fly
head development GO:0060322 303 0.556
Zebrafish
neural tube development GO:0021915 62 0.553
Zebrafish
regionalization GO:0003002 274 0.551
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.542
Mouse
cell migration involved in heart development GO:0060973 22 0.518
Zebrafish
fluid transport GO:0042044 17 0.510
Zebrafish
negative regulation of biosynthetic process GO:0009890 55 0.484
Mouse
cellular response to external stimulus GO:0071496 2 0.482
Rat
cation transport GO:0006812 81 0.477
Human Zebrafish Mouse Rat Worm Fly
membrane repolarization GO:0086009 2 0.466
Human
membrane hyperpolarization GO:0060081 1 0.457
Rat
ventricular system development GO:0021591 12 0.451
Zebrafish
ion transmembrane transport GO:0034220 91 0.449
Human Zebrafish Mouse Rat Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.446
Human Zebrafish Mouse Rat Worm Fly
apical junction assembly GO:0043297 1 0.428
Fly
response to drug GO:0042493 3 0.406
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.403
anterior posterior pattern specification GO:0009952 152 0.396
Zebrafish
inner ear morphogenesis GO:0042472 63 0.395
monovalent inorganic cation transport GO:0015672 42 0.389
Human Zebrafish Mouse Rat Worm Fly
regulation of biological quality GO:0065008 263 0.388
Human Zebrafish Mouse Rat Worm Fly
cellular biosynthetic process GO:0044249 286 0.378
Mouse
heterocycle metabolic process GO:0046483 290 0.375
Human Zebrafish Mouse Rat Worm Fly
negative regulation of cellular process GO:0048523 283 0.373
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.363
Human Zebrafish Mouse Rat Worm Fly
negative regulation of biological process GO:0048519 304 0.362
Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.354
Human Zebrafish Mouse Rat Worm Fly
glucocorticoid metabolic process GO:0008211 2 0.338
Mouse
embryonic organ morphogenesis GO:0048562 274 0.317
regulation of biosynthetic process GO:0009889 250 0.300
Mouse
heart morphogenesis GO:0003007 156 0.285
Zebrafish
divalent inorganic cation homeostasis GO:0072507 22 0.282
Zebrafish
establishment of localization GO:0051234 244 0.282
Human Zebrafish Mouse Rat Worm Fly
regulation of hormone levels GO:0010817 21 0.279
Mouse
atp catabolic process GO:0006200 4 0.251
Human Zebrafish Mouse Rat Worm Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.246
Human Zebrafish Mouse Rat Worm Fly
embryonic heart tube morphogenesis GO:0003143 108 0.242
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.240
Zebrafish
single organism localization GO:1902578 225 0.231
Human Zebrafish Mouse Rat Worm Fly
rna biosynthetic process GO:0032774 181 0.231
cellular aromatic compound metabolic process GO:0006725 295 0.226
Human Zebrafish Mouse Rat Worm Fly
cation transmembrane transport GO:0098655 65 0.223
Human Zebrafish Mouse Rat Worm Fly
small molecule metabolic process GO:0044281 77 0.221
Human Zebrafish Mouse Rat Worm Fly
regulation of blood circulation GO:1903522 32 0.220
Mouse Rat
semicircular canal morphogenesis GO:0048752 18 0.214
metal ion transport GO:0030001 58 0.212
Human Zebrafish Mouse Rat Worm Fly
system process GO:0003008 185 0.208
Zebrafish Mouse Rat Worm Fly
eye development GO:0001654 277 0.208
specification of organ axis polarity GO:0010084 2 0.202
Zebrafish
action potential GO:0001508 19 0.202
Worm
heart development GO:0007507 313 0.197
Zebrafish
circulatory system process GO:0003013 87 0.195
Zebrafish Mouse Rat
transport GO:0006810 220 0.195
Human Zebrafish Mouse Rat Worm Fly
muscle contraction GO:0006936 18 0.194
Mouse Rat Worm
organic substance biosynthetic process GO:1901576 289 0.193
Mouse
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.193
Human
hormone metabolic process GO:0042445 19 0.192
Mouse
cell migration involved in heart formation GO:0060974 10 0.179
Zebrafish
heart looping GO:0001947 94 0.172
Zebrafish
rostrocaudal neural tube patterning GO:0021903 29 0.166
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.163
synaptic growth at neuromuscular junction GO:0051124 2 0.162
Fly
positive regulation of blood circulation GO:1903524 2 0.160
Mouse
lateral line system development GO:0048925 76 0.160
regulation of anatomical structure morphogenesis GO:0022603 130 0.160
Fly
regulation of metal ion transport GO:0010959 4 0.158
Rat
stem cell differentiation GO:0048863 117 0.155
homeostatic process GO:0042592 142 0.154
Human Zebrafish Fly
otic placode formation GO:0043049 23 0.153
embryonic organ development GO:0048568 381 0.151
determination of heart left right asymmetry GO:0061371 117 0.150
Zebrafish
epidermal cell fate specification GO:0009957 4 0.149
chemical homeostasis GO:0048878 49 0.148
Human Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.147
Zebrafish Worm Fly
ammonia homeostasis GO:0097272 3 0.143
cellular nitrogen compound metabolic process GO:0034641 290 0.142
Human Zebrafish Mouse Rat Worm Fly
cellular component biogenesis GO:0044085 178 0.136
Fly
stem cell maintenance GO:0019827 4 0.135
brain development GO:0007420 293 0.134
Zebrafish
central nervous system development GO:0007417 387 0.133
Zebrafish
response to organic substance GO:0010033 153 0.132
Human
retina development in camera type eye GO:0060041 146 0.132
stem cell development GO:0048864 82 0.130
regulation of membrane potential GO:0042391 23 0.129
Human Rat Worm
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.128
regulation of blood pressure GO:0008217 1 0.126
Mouse
regulation of rna metabolic process GO:0051252 224 0.125
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.125
Human Zebrafish Mouse Rat Worm Fly
chordate embryonic development GO:0043009 271 0.122
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.120
Zebrafish
regulation of heart contraction GO:0008016 32 0.120
Mouse Rat
negative regulation of metabolic process GO:0009892 86 0.120
Mouse
aging GO:0007568 2 0.118
Fly
cardiac muscle cell contraction GO:0086003 1 0.118
Rat
actin mediated cell contraction GO:0070252 1 0.118
Rat
pigmentation GO:0043473 85 0.116
kidney development GO:0001822 92 0.116
sympathetic nervous system development GO:0048485 3 0.116
regulation of primary metabolic process GO:0080090 311 0.114
Mouse
axon ensheathment in central nervous system GO:0032291 2 0.110
sodium ion transmembrane transport GO:0035725 21 0.108
Human Zebrafish Mouse Rat Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.105
organonitrogen compound metabolic process GO:1901564 74 0.105
Human Zebrafish Mouse Rat Worm Fly
cellular response to endogenous stimulus GO:0071495 68 0.105
Human
cellular response to hormone stimulus GO:0032870 39 0.103
Human
central nervous system myelin formation GO:0032289 1 0.101
regulation of nitrogen compound metabolic process GO:0051171 251 0.101
generation of neurons GO:0048699 385 0.100
axis specification GO:0009798 43 0.099
Zebrafish
ameboidal type cell migration GO:0001667 143 0.099
cell motility GO:0048870 244 0.099
Zebrafish
inorganic cation transmembrane transport GO:0098662 50 0.098
Human Zebrafish Mouse Rat Worm Fly
negative regulation of protein phosphorylation GO:0001933 4 0.098
single organism transport GO:0044765 206 0.096
Human Zebrafish Mouse Rat Worm Fly
neural crest cell migration GO:0001755 42 0.096
tube morphogenesis GO:0035239 349 0.096
protein localization to nucleus GO:0034504 3 0.095
hormone biosynthetic process GO:0042446 3 0.094
Mouse
regulation of cardiac muscle contraction GO:0055117 2 0.092
Rat
cardiocyte differentiation GO:0035051 44 0.092
Zebrafish
regulation of developmental process GO:0050793 247 0.091
Fly
specification of symmetry GO:0009799 204 0.091
Zebrafish
regulation of vascular permeability GO:0043114 5 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.090
rna metabolic process GO:0016070 219 0.089
ion transport GO:0006811 114 0.089
Human Zebrafish Mouse Rat Worm Fly
mesoderm morphogenesis GO:0048332 51 0.088
adult behavior GO:0030534 2 0.087
Fly
growth GO:0040007 174 0.087
Worm Fly
cellular amino acid metabolic process GO:0006520 7 0.085
regulation of ph GO:0006885 3 0.085
ion homeostasis GO:0050801 41 0.084
Human Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.084
cellular response to extracellular stimulus GO:0031668 2 0.081
cartilage development GO:0051216 96 0.079
regulation of striated muscle contraction GO:0006942 2 0.077
Mouse Rat
muscle organ development GO:0007517 101 0.077
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.076
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.076
anion homeostasis GO:0055081 9 0.075
central nervous system myelination GO:0022010 2 0.074
potassium ion transmembrane transport GO:0071805 10 0.073
Human Zebrafish Mouse Rat Worm Fly
mesenchymal cell differentiation GO:0048762 87 0.073
regulation of macromolecule biosynthetic process GO:0010556 225 0.073
heart contraction GO:0060047 71 0.070
Zebrafish Mouse Rat
lens morphogenesis in camera type eye GO:0002089 7 0.068
embryonic heart tube development GO:0035050 133 0.068
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.068
regulation of system process GO:0044057 40 0.068
Mouse Rat Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.067
cellular macromolecule biosynthetic process GO:0034645 224 0.066
sodium ion homeostasis GO:0055078 3 0.065
Human
enteric nervous system development GO:0048484 12 0.065
response to stress GO:0006950 263 0.065
organic acid metabolic process GO:0006082 31 0.064
positive regulation of heart contraction GO:0045823 2 0.063
Mouse
response to endogenous stimulus GO:0009719 83 0.063
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.062
Mouse
macromolecule biosynthetic process GO:0009059 227 0.062
ectodermal placode morphogenesis GO:0071697 32 0.060
renal system development GO:0072001 94 0.059
neural plate anterior posterior regionalization GO:0021999 8 0.059
lens development in camera type eye GO:0002088 22 0.059
epithelial cell differentiation GO:0030855 116 0.059
regulation of gene expression GO:0010468 265 0.059
regulation of ion transport GO:0043269 22 0.058
Rat
regulation of sequestering of calcium ion GO:0051282 4 0.058
multicellular organismal homeostasis GO:0048871 29 0.058
Fly
amine metabolic process GO:0009308 2 0.057
transmembrane transport GO:0055085 120 0.057
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.057
Mouse
muscle tissue development GO:0060537 110 0.056
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.056
somatic stem cell maintenance GO:0035019 1 0.056
cranial ganglion development GO:0061550 3 0.055
protein targeting to nucleus GO:0044744 3 0.055
gene expression GO:0010467 252 0.054
water homeostasis GO:0030104 4 0.054
positive regulation of rna metabolic process GO:0051254 59 0.054
hormone transport GO:0009914 2 0.054
blood circulation GO:0008015 87 0.053
Zebrafish Mouse Rat
cation homeostasis GO:0055080 33 0.052
Human Zebrafish
cellular response to lipid GO:0071396 39 0.052
Human
sensory perception of sound GO:0007605 9 0.051
Fly
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.050
positive regulation of biological process GO:0048518 253 0.050
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.049
mesenchyme development GO:0060485 127 0.049
mesenchymal cell development GO:0014031 78 0.049
extrinsic apoptotic signaling pathway GO:0097191 3 0.048
transcription dna templated GO:0006351 181 0.048
pectoral fin development GO:0033339 50 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
somite development GO:0061053 96 0.048
embryonic digestive tract development GO:0048566 4 0.047
cellular ketone metabolic process GO:0042180 11 0.047
nephron epithelium morphogenesis GO:0072088 1 0.046
neural tube patterning GO:0021532 33 0.046
Zebrafish
tissue homeostasis GO:0001894 25 0.046
Fly
locomotion GO:0040011 313 0.046
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.046
regulation of nucleic acid templated transcription GO:1903506 213 0.045
cardiac muscle contraction GO:0060048 6 0.045
Rat
cell migration GO:0016477 237 0.044
Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.044
nucleic acid metabolic process GO:0090304 244 0.043
camera type eye development GO:0043010 222 0.043
ammonium transmembrane transport GO:0072488 2 0.043
regulation of cellular component movement GO:0051270 55 0.043
Rat
cellular component assembly GO:0022607 170 0.043
Fly
glucocorticoid biosynthetic process GO:0006704 1 0.043
Mouse
positive regulation of transport GO:0051050 2 0.043
oxoacid metabolic process GO:0043436 31 0.043
urogenital system development GO:0001655 97 0.043
cellular response to organic substance GO:0071310 105 0.042
Human
negative regulation of mitosis GO:0045839 3 0.042
axial mesoderm development GO:0048318 10 0.042
negative regulation of cellular metabolic process GO:0031324 77 0.042
Mouse
myelin assembly GO:0032288 1 0.042
amide transport GO:0042886 12 0.041
developmental pigmentation GO:0048066 48 0.041
neural crest cell differentiation GO:0014033 72 0.041
cellular component morphogenesis GO:0032989 336 0.039
Fly
segmentation GO:0035282 97 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
catecholamine biosynthetic process GO:0042423 2 0.039
phenol containing compound biosynthetic process GO:0046189 4 0.039
embryonic digestive tract morphogenesis GO:0048557 3 0.039
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.038
response to oxygen containing compound GO:1901700 55 0.038
Human
muscle structure development GO:0061061 196 0.037
Zebrafish
lateral line ganglion development GO:0048890 2 0.037
regulation of signaling GO:0023051 235 0.037
response to hormone GO:0009725 48 0.037
Human
positive regulation of gene expression GO:0010628 71 0.037
synapse organization GO:0050808 21 0.037
Fly
glial cell development GO:0021782 20 0.036
cellular response to steroid hormone stimulus GO:0071383 31 0.036
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.035
camera type eye morphogenesis GO:0048593 108 0.035
thigmotaxis GO:0001966 5 0.035
Zebrafish
cellular amine metabolic process GO:0044106 2 0.035
peripheral nervous system development GO:0007422 55 0.035
neurological system process GO:0050877 62 0.035
Fly
neural crest cell development GO:0014032 62 0.035
hatching gland development GO:0048785 3 0.035
cellular component movement GO:0006928 335 0.034
Zebrafish Rat
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.034
negative regulation of endothelial cell migration GO:0010596 1 0.034
dopamine biosynthetic process GO:0042416 2 0.034
negative regulation of apoptotic process GO:0043066 55 0.034
regulation of calcium ion transport GO:0051924 2 0.034
floor plate development GO:0033504 15 0.034
regulation of transcription dna templated GO:0006355 213 0.033
ectodermal placode development GO:0071696 37 0.033
epidermal cell differentiation GO:0009913 36 0.033
regulation of transport GO:0051049 45 0.033
Rat
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.033
regulation of cellular component organization GO:0051128 86 0.033
Fly
female sex differentiation GO:0046660 4 0.033
regulation of cellular response to growth factor stimulus GO:0090287 35 0.033
regulation of multicellular organismal process GO:0051239 277 0.033
Mouse Rat Worm
hormone secretion GO:0046879 2 0.033
eye morphogenesis GO:0048592 144 0.032
cell junction organization GO:0034330 11 0.032
Fly
cell surface receptor signaling pathway GO:0007166 325 0.032
biosynthetic process GO:0009058 294 0.032
Mouse
pronephros development GO:0048793 69 0.031
cellular response to chemical stimulus GO:0070887 157 0.031
Human
localization of cell GO:0051674 244 0.031
Zebrafish
lipid catabolic process GO:0016042 4 0.031
monovalent inorganic anion homeostasis GO:0055083 6 0.031
cellular response to organic cyclic compound GO:0071407 38 0.031
Human
positive regulation of transcription dna templated GO:0045893 57 0.031
erythrocyte homeostasis GO:0034101 55 0.030
response to lipid GO:0033993 60 0.030
Human
stem cell proliferation GO:0072089 4 0.030
determination of bilateral symmetry GO:0009855 204 0.030
Zebrafish
heterocycle catabolic process GO:0046700 15 0.030
Human Zebrafish Mouse Rat Worm Fly
regulation of catalytic activity GO:0050790 55 0.029
endocrine system development GO:0035270 65 0.029
single organism metabolic process GO:0044710 217 0.029
Human Zebrafish Mouse Rat Worm Fly
regulation of transporter activity GO:0032409 2 0.029
maintenance of location GO:0051235 4 0.029
negative regulation of map kinase activity GO:0043407 2 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
regulation of metabolic process GO:0019222 359 0.028
Mouse
pigment cell differentiation GO:0050931 38 0.028
response to chemical GO:0042221 320 0.028
Human Mouse
response to organic cyclic compound GO:0014070 51 0.028
Human
ectodermal placode formation GO:0060788 26 0.028
purine containing compound metabolic process GO:0072521 29 0.028
Human Zebrafish Mouse Rat Worm Fly
nucleic acid templated transcription GO:0097659 181 0.028
protein import into nucleus GO:0006606 3 0.028
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
Human Zebrafish Mouse Rat Worm Fly
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.027
nephron morphogenesis GO:0072028 2 0.027
regulation of cell morphogenesis GO:0022604 42 0.027
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.027
positive regulation of metabolic process GO:0009893 108 0.027
extracellular matrix organization GO:0030198 27 0.027
Zebrafish
purine ribonucleotide metabolic process GO:0009150 27 0.027
Human Zebrafish Mouse Rat Worm Fly
nephron epithelium development GO:0072009 16 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.026
heart process GO:0003015 71 0.026
Zebrafish Mouse Rat
extracellular structure organization GO:0043062 27 0.026
Zebrafish
connective tissue development GO:0061448 99 0.025
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.025
cellular nitrogen compound catabolic process GO:0044270 15 0.025
Human Zebrafish Mouse Rat Worm Fly
lateral line nerve development GO:0048892 9 0.025
regulation of reproductive process GO:2000241 4 0.024
nucleoside phosphate metabolic process GO:0006753 28 0.024
Human Zebrafish Mouse Rat Worm Fly
lipid metabolic process GO:0006629 52 0.024
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
negative regulation of transcription dna templated GO:0045892 45 0.023
regulation of programmed cell death GO:0043067 101 0.023
regulation of apoptotic process GO:0042981 98 0.023
regulation of lipid biosynthetic process GO:0046890 8 0.023
Mouse
cytokinesis GO:0000910 3 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
regulation of tube size GO:0035150 2 0.023
Fly
taxis GO:0042330 109 0.023
Zebrafish
muscle system process GO:0003012 20 0.023
Mouse Rat Worm
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.023
death GO:0016265 121 0.022
skeletal system morphogenesis GO:0048705 102 0.022
somitogenesis GO:0001756 87 0.022
skeletal system development GO:0001501 181 0.022
vasculature development GO:0001944 278 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
catechol containing compound metabolic process GO:0009712 2 0.022
regulation of localization GO:0032879 104 0.022
Rat
carbohydrate derivative metabolic process GO:1901135 61 0.022
Human Zebrafish Mouse Rat Worm Fly
regulation of cytoplasmic transport GO:1903649 4 0.022
skeletal muscle tissue development GO:0007519 67 0.022
Zebrafish
response to glucose GO:0009749 3 0.021
regulation of cardiac muscle cell contraction GO:0086004 1 0.021
Rat
protein import GO:0017038 3 0.021
signal transduction GO:0007165 455 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
Human Zebrafish Mouse Rat Worm Fly
cellular macromolecule metabolic process GO:0044260 391 0.021
response to steroid hormone GO:0048545 35 0.021
Human
skeletal muscle organ development GO:0060538 78 0.021
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.021
cell part morphogenesis GO:0032990 246 0.021
catechol containing compound biosynthetic process GO:0009713 2 0.021
regulation of sodium ion transmembrane transport GO:1902305 1 0.020
apoptotic process GO:0006915 116 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
autonomic nervous system development GO:0048483 19 0.020
catabolic process GO:0009056 32 0.020
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular protein metabolic process GO:0032268 52 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
endoderm development GO:0007492 49 0.020
organelle fusion GO:0048284 3 0.020
hepaticobiliary system development GO:0061008 98 0.020
digestive tract development GO:0048565 265 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of jun kinase activity GO:0043506 3 0.019
regulation of muscle system process GO:0090257 5 0.019
Mouse Rat Worm
cellular catabolic process GO:0044248 27 0.019
Human Zebrafish Mouse Rat Worm Fly
internal protein amino acid acetylation GO:0006475 2 0.019
sequestering of metal ion GO:0051238 3 0.019
programmed cell death GO:0012501 119 0.019
body morphogenesis GO:0010171 16 0.019
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.019
cell death GO:0008219 121 0.019
protein acetylation GO:0006473 2 0.019
gliogenesis GO:0042063 45 0.018
cell cell signaling GO:0007267 52 0.018
Fly
axial mesoderm morphogenesis GO:0048319 8 0.018
neuromuscular junction development GO:0007528 9 0.018
Fly
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.018
developmental growth GO:0048589 166 0.018
Fly
neuron differentiation GO:0030182 353 0.018
axis elongation GO:0003401 31 0.018
tissue regeneration GO:0042246 74 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
dopamine metabolic process GO:0042417 2 0.018
negative regulation of cell death GO:0060548 60 0.018
positive regulation of cellular process GO:0048522 201 0.018
response to carbohydrate GO:0009743 3 0.018
regulation of cell shape GO:0008360 1 0.018
Fly
small molecule catabolic process GO:0044282 3 0.017
melanocyte differentiation GO:0030318 26 0.017
organelle organization GO:0006996 227 0.017
locomotory behavior GO:0007626 34 0.017
Zebrafish Fly
negative regulation of rna metabolic process GO:0051253 48 0.017
renal tubule morphogenesis GO:0061333 1 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
protein localization to plasma membrane GO:0072659 1 0.017
oligodendrocyte development GO:0014003 7 0.017
positive regulation of translation GO:0045727 1 0.017
determination of left right symmetry GO:0007368 179 0.017
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of cell death GO:0010941 103 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.016
striated muscle tissue development GO:0014706 110 0.016
Zebrafish
positive regulation of lipid metabolic process GO:0045834 1 0.016
meiotic cell cycle process GO:1903046 3 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
Rat
angiogenesis GO:0001525 158 0.016
nucleobase containing compound catabolic process GO:0034655 15 0.016
Human Zebrafish Mouse Rat Worm Fly
immunoglobulin mediated immune response GO:0016064 3 0.016
neuronal action potential GO:0019228 18 0.016
response to ketone GO:1901654 1 0.016
type b pancreatic cell development GO:0003323 4 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
peptidyl lysine acetylation GO:0018394 2 0.015
regulation of protein transport GO:0051223 3 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
phosphorus metabolic process GO:0006793 109 0.015
Human Zebrafish Mouse Rat Worm Fly
transmission of nerve impulse GO:0019226 19 0.015
mesoderm development GO:0007498 88 0.015
negative regulation of kinase activity GO:0033673 4 0.015
release of sequestered calcium ion into cytosol GO:0051209 3 0.015
regulation of cellular ph GO:0030641 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
Mouse
regulation of hormone secretion GO:0046883 2 0.015
steroid biosynthetic process GO:0006694 5 0.015
Mouse
negative regulation of protein metabolic process GO:0051248 16 0.015
negative regulation of gene expression GO:0010629 65 0.015
lateral line nerve glial cell differentiation GO:0048895 6 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
inorganic anion transport GO:0015698 25 0.014
nucleoside metabolic process GO:0009116 11 0.014
Human Zebrafish Mouse Rat Worm Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
response to hexose GO:0009746 3 0.014
cell morphogenesis GO:0000902 289 0.014
Fly
protein acylation GO:0043543 3 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
single organism biosynthetic process GO:0044711 71 0.014
Mouse
single organism catabolic process GO:0044712 13 0.014
Human Zebrafish Mouse Rat Worm Fly
response to growth factor GO:0070848 39 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
Mouse
neurotransmitter transport GO:0006836 2 0.014
protein metabolic process GO:0019538 183 0.014
Worm
immune system development GO:0002520 191 0.014
actin filament based process GO:0030029 64 0.014
Rat
cell cell junction organization GO:0045216 10 0.014
Fly
cellular cation homeostasis GO:0030003 17 0.014
Human Zebrafish
auditory receptor cell fate commitment GO:0009912 4 0.014
gas transport GO:0015669 3 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
apoptotic process involved in development GO:1902742 2 0.013
positive regulation of catabolic process GO:0009896 4 0.013
lens fiber cell development GO:0070307 3 0.013
negative regulation of reproductive process GO:2000242 3 0.013
smooth muscle contraction GO:0006939 2 0.013
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.013
organic cyclic compound catabolic process GO:1901361 15 0.013
Human Zebrafish Mouse Rat Worm Fly
peptide transport GO:0015833 1 0.013
actin filament based movement GO:0030048 1 0.013
Rat
embryonic skeletal system development GO:0048706 97 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
phagocytosis GO:0006909 3 0.013
synaptic transmission GO:0007268 35 0.013
Fly
female gonad development GO:0008585 4 0.013
divalent inorganic anion homeostasis GO:0072505 5 0.013
epithelial cell proliferation GO:0050673 17 0.012
regulation of cell activation GO:0050865 1 0.012

atp1a1a.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.079
disease of anatomical entity DOID:7 0 0.079
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013