Danio rerio

21 known processes

tcf7

transcription factor 7 (T-cell specific, HMG-box)

tcf7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.962
Zebrafish Mouse
posterior lateral line development GO:0048916 38 0.936
Zebrafish
generation of neurons GO:0048699 385 0.922
Zebrafish Worm
canonical wnt signaling pathway GO:0060070 48 0.897
Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.893
Zebrafish
pectoral fin development GO:0033339 50 0.851
negative regulation of biological process GO:0048519 304 0.839
Zebrafish Mouse Worm Fly
mechanosensory lateral line system development GO:0048881 49 0.822
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.819
liver development GO:0001889 96 0.816
brain development GO:0007420 293 0.814
Zebrafish
cell migration GO:0016477 237 0.811
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.782
Zebrafish Fly
cellular aromatic compound metabolic process GO:0006725 295 0.773
Mouse Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.770
Mouse Worm Fly
regulation of epithelial to mesenchymal transition GO:0010717 3 0.765
glycoprotein metabolic process GO:0009100 23 0.760
mesenchymal cell differentiation GO:0048762 87 0.756
Zebrafish
regulation of signal transduction GO:0009966 225 0.750
Zebrafish Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.746
Mouse Worm Fly
embryonic organ morphogenesis GO:0048562 274 0.736
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.734
Zebrafish Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.726
cell motility GO:0048870 244 0.726
Zebrafish
cell projection morphogenesis GO:0048858 244 0.687
negative regulation of cellular process GO:0048523 283 0.682
Zebrafish Mouse Worm Fly
eye development GO:0001654 277 0.678
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.668
posterior lateral line system development GO:0048915 46 0.668
Zebrafish
appendage development GO:0048736 80 0.645
positive regulation of biological process GO:0048518 253 0.644
Zebrafish Worm Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.644
cell surface receptor signaling pathway GO:0007166 325 0.631
Zebrafish Mouse Fly
regulation of cell communication GO:0010646 232 0.610
Zebrafish Fly
nuclear import GO:0051170 3 0.609
larval development GO:0002164 2 0.602
Worm
regulation of signaling GO:0023051 235 0.602
Zebrafish Fly
negative regulation of multicellular organismal process GO:0051241 69 0.596
Worm
regulation of transcription involved in cell fate commitment GO:0060850 1 0.586
morphogenesis of an epithelium GO:0002009 333 0.560
localization of cell GO:0051674 244 0.556
Zebrafish
gland development GO:0048732 143 0.551
Fly
ameboidal type cell migration GO:0001667 143 0.541
Zebrafish
embryonic neurocranium morphogenesis GO:0048702 15 0.540
hepaticobiliary system development GO:0061008 98 0.530
wnt signaling pathway GO:0016055 80 0.525
Zebrafish Mouse Fly
skin development GO:0043588 54 0.513
transcription dna templated GO:0006351 181 0.507
Mouse Worm Fly
signal transduction GO:0007165 455 0.502
Zebrafish Mouse Fly
inner ear development GO:0048839 126 0.498
protein import GO:0017038 3 0.494
rhombomere development GO:0021546 19 0.492
single organism biosynthetic process GO:0044711 71 0.488
Zebrafish
lateral line development GO:0048882 66 0.478
Zebrafish
regulation of cellular response to growth factor stimulus GO:0090287 35 0.472
bmp signaling pathway GO:0030509 52 0.461
lymphocyte differentiation GO:0030098 9 0.445
Mouse
regulation of rna metabolic process GO:0051252 224 0.443
Mouse Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.440
Zebrafish Worm Fly
heart field specification GO:0003128 1 0.439
mesenchymal cell proliferation GO:0010463 1 0.438
negative regulation of developmental process GO:0051093 65 0.437
Worm
proteoglycan metabolic process GO:0006029 14 0.437
cell proliferation in dorsal spinal cord GO:0010456 2 0.436
Zebrafish
multicellular organism growth GO:0035264 4 0.433
growth GO:0040007 174 0.403
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.400
positive regulation of programmed cell death GO:0043068 29 0.398
mesenchyme development GO:0060485 127 0.388
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.382
regulation of growth GO:0040008 42 0.382
regulation of gene expression GO:0010468 265 0.381
Zebrafish Mouse Worm Fly
cellular component morphogenesis GO:0032989 336 0.379
regulation of establishment of protein localization GO:0070201 4 0.370
posterior lateral line neuromast deposition GO:0048922 5 0.370
Zebrafish
cartilage development GO:0051216 96 0.365
regulation of stem cell differentiation GO:2000736 4 0.360
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.356
regulation of protein transport GO:0051223 3 0.340
regeneration GO:0031099 91 0.338
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.338
Mouse Worm Fly
catenin import into nucleus GO:0035411 2 0.337
neural crest cell migration GO:0001755 42 0.334
Zebrafish
anterior posterior axon guidance GO:0033564 5 0.333
protein localization to nucleus GO:0034504 3 0.322
proteoglycan biosynthetic process GO:0030166 12 0.319
developmental growth involved in morphogenesis GO:0060560 86 0.312
regulation of response to stimulus GO:0048583 269 0.311
Zebrafish Fly
formation of anatomical boundary GO:0048859 14 0.309
regulation of cellular biosynthetic process GO:0031326 245 0.299
Zebrafish Mouse Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.297
Zebrafish Mouse Worm
embryonic camera type eye development GO:0031076 29 0.295
Zebrafish
protein import into nucleus GO:0006606 3 0.294
steroid hormone mediated signaling pathway GO:0043401 9 0.293
protein targeting to nucleus GO:0044744 3 0.291
skeletal system morphogenesis GO:0048705 102 0.289
macromolecule biosynthetic process GO:0009059 227 0.278
Mouse Worm Fly
regulation of epithelial cell proliferation GO:0050678 3 0.275
response to growth factor GO:0070848 39 0.272
positive regulation of muscle cell differentiation GO:0051149 1 0.272
regulation of protein import into nucleus GO:0042306 2 0.271
regulation of ossification GO:0030278 5 0.271
defense response to other organism GO:0098542 33 0.268
heart formation GO:0060914 13 0.262
ossification GO:0001503 23 0.257
embryonic pectoral fin morphogenesis GO:0035118 24 0.253
single organism nuclear import GO:1902593 3 0.245
positive regulation of apoptotic process GO:0043065 29 0.245
neuron fate commitment GO:0048663 26 0.241
embryonic appendage morphogenesis GO:0035113 30 0.241
connective tissue development GO:0061448 99 0.240
regulation of neurogenesis GO:0050767 87 0.237
Zebrafish
cell morphogenesis GO:0000902 289 0.232
regulation of extent of cell growth GO:0061387 29 0.229
developmental growth GO:0048589 166 0.229
Zebrafish
stem cell development GO:0048864 82 0.228
Zebrafish
eye morphogenesis GO:0048592 144 0.226
Zebrafish
medial fin development GO:0033338 16 0.224
Zebrafish
regulation of protein targeting GO:1903533 2 0.223
negative regulation of rna biosynthetic process GO:1902679 45 0.223
Worm Fly
embryonic camera type eye morphogenesis GO:0048596 19 0.223
Zebrafish
regulation of axon extension GO:0030516 24 0.222
regulation of rna biosynthetic process GO:2001141 213 0.219
Mouse Worm Fly
regulation of bmp signaling pathway GO:0030510 39 0.218
cell projection organization GO:0030030 284 0.215
cilium morphogenesis GO:0060271 85 0.215
sensory system development GO:0048880 76 0.214
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.212
Worm Fly
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.210
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.206
Mouse Worm Fly
extracellular structure organization GO:0043062 27 0.205
rna biosynthetic process GO:0032774 181 0.202
Mouse Worm Fly
pituitary gland development GO:0021983 16 0.202
inner ear morphogenesis GO:0042472 63 0.201
collagen biosynthetic process GO:0032964 2 0.200
positive regulation of signal transduction GO:0009967 56 0.195
camera type eye development GO:0043010 222 0.193
Zebrafish
rna metabolic process GO:0016070 219 0.189
Mouse Worm Fly
face development GO:0060324 8 0.187
regulation of multicellular organismal development GO:2000026 223 0.184
Zebrafish Worm
multicellular organismal macromolecule metabolic process GO:0044259 2 0.184
regulation of axon extension involved in axon guidance GO:0048841 6 0.182
sensory organ morphogenesis GO:0090596 200 0.182
Zebrafish
single organism metabolic process GO:0044710 217 0.178
Zebrafish
mesenchymal cell development GO:0014031 78 0.178
Zebrafish
cranial suture morphogenesis GO:0060363 1 0.177
regulation of nucleocytoplasmic transport GO:0046822 2 0.177
protein metabolic process GO:0019538 183 0.177
negative regulation of nucleic acid templated transcription GO:1903507 45 0.175
Worm Fly
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.174
regulation of stem cell proliferation GO:0072091 2 0.173
Fly
forebrain development GO:0030900 96 0.172
Zebrafish
swim bladder development GO:0048794 19 0.170
regulation of oligodendrocyte differentiation GO:0048713 1 0.166
cellular protein localization GO:0034613 20 0.166
negative regulation of protein import into nucleus GO:0042308 2 0.166
regulation of anatomical structure morphogenesis GO:0022603 130 0.166
regulation of glial cell differentiation GO:0045685 4 0.165
oligodendrocyte differentiation GO:0048709 23 0.164
regulation of cell differentiation GO:0045595 142 0.163
Zebrafish Worm Fly
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.161
regulation of multicellular organism growth GO:0040014 4 0.160
negative regulation of epithelial cell proliferation GO:0050680 1 0.159
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.157
Worm Fly
nucleic acid metabolic process GO:0090304 244 0.157
Mouse Worm Fly
negative regulation of reproductive process GO:2000242 3 0.155
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.152
Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.151
Mouse Worm Fly
glial cell migration GO:0008347 3 0.151
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.150
cellular nitrogen compound biosynthetic process GO:0044271 218 0.147
Mouse Worm Fly
organic substance biosynthetic process GO:1901576 289 0.146
Zebrafish Mouse Worm Fly
hindbrain development GO:0030902 91 0.146
Zebrafish
regulation of developmental process GO:0050793 247 0.146
Zebrafish Worm Fly
heterocycle biosynthetic process GO:0018130 215 0.144
Mouse Worm Fly
cilium assembly GO:0042384 58 0.142
response to bacterium GO:0009617 58 0.142
negative regulation of cell communication GO:0010648 96 0.141
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.140
Worm Fly
morphogenesis of a branching epithelium GO:0061138 16 0.138
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.135
Worm Fly
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.134
signal transduction in absence of ligand GO:0038034 1 0.133
cell proliferation GO:0008283 80 0.131
Zebrafish Mouse Fly
regionalization GO:0003002 274 0.130
gliogenesis GO:0042063 45 0.130
regulation of notch signaling pathway GO:0008593 16 0.128
craniofacial suture morphogenesis GO:0097094 2 0.123
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.120
heart morphogenesis GO:0003007 156 0.118
positive regulation of signaling GO:0023056 56 0.116
chromatin modification GO:0016568 21 0.114
regulation of endothelial cell proliferation GO:0001936 1 0.114
regulation of nucleic acid templated transcription GO:1903506 213 0.113
Mouse Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.111
Mouse Worm Fly
hard palate development GO:0060022 4 0.111
protein localization GO:0008104 40 0.110
negative regulation of cell differentiation GO:0045596 46 0.110
specification of organ identity GO:0010092 2 0.109
nuclear transport GO:0051169 4 0.108
cellular protein catabolic process GO:0044257 4 0.107
cell migration involved in gastrulation GO:0042074 79 0.107
embryonic heart tube morphogenesis GO:0003143 108 0.107
regulation of retinoic acid biosynthetic process GO:1900052 6 0.106
Zebrafish
multicellular organismal metabolic process GO:0044236 2 0.104
pronephros development GO:0048793 69 0.104
epidermis development GO:0008544 48 0.103
response to organic substance GO:0010033 153 0.103
cell part morphogenesis GO:0032990 246 0.103
epithelial to mesenchymal transition GO:0001837 21 0.103
response to chemical GO:0042221 320 0.102
regulation of catenin import into nucleus GO:0035412 2 0.101
regulation of axonogenesis GO:0050770 32 0.101
positive regulation of gastrulation GO:2000543 2 0.100
positive regulation of cell morphogenesis involved in differentiation GO:0010770 6 0.100
negative regulation of bmp signaling pathway GO:0030514 13 0.098
negative regulation of metabolic process GO:0009892 86 0.097
Worm Fly
ectodermal placode development GO:0071696 37 0.097
chordate embryonic development GO:0043009 271 0.097
Zebrafish Mouse
cellular component movement GO:0006928 335 0.097
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.097
Zebrafish Worm Fly
adenohypophysis development GO:0021984 15 0.096
regulation of protein binding GO:0043393 3 0.095
retina development in camera type eye GO:0060041 146 0.095
positive regulation of cell differentiation GO:0045597 30 0.093
Zebrafish
cell fate specification GO:0001708 68 0.092
Worm
sprouting angiogenesis GO:0002040 53 0.092
positive regulation of muscle organ development GO:0048636 1 0.091
wound healing GO:0042060 90 0.091
Zebrafish
notch signaling pathway GO:0007219 35 0.090
cellular macromolecule localization GO:0070727 21 0.090
regulation of axon guidance GO:1902667 8 0.090
positive regulation of cell communication GO:0010647 56 0.090
regulation of mesenchymal cell proliferation GO:0010464 1 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.089
axonogenesis GO:0007409 152 0.089
collagen fibril organization GO:0030199 1 0.089
chemosensory behavior GO:0007635 1 0.088
ectodermal placode formation GO:0060788 26 0.086
bone development GO:0060348 14 0.085
radial glial cell differentiation GO:0060019 2 0.085
bone mineralization GO:0030282 9 0.085
heart looping GO:0001947 94 0.084
negative regulation of signaling GO:0023057 96 0.083
Zebrafish
biosynthetic process GO:0009058 294 0.082
Zebrafish Mouse Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.082
negative regulation of cytoplasmic transport GO:1903650 2 0.082
epithelial cell differentiation GO:0030855 116 0.082
positive regulation of apoptotic signaling pathway GO:2001235 1 0.081
odontogenesis of dentin containing tooth GO:0042475 1 0.081
aging GO:0007568 2 0.080
nucleic acid templated transcription GO:0097659 181 0.079
Mouse Worm Fly
sulfur compound metabolic process GO:0006790 13 0.079
retinal ganglion cell axon guidance GO:0031290 35 0.079
cellular response to organic substance GO:0071310 105 0.079
transcription from rna polymerase ii promoter GO:0006366 80 0.079
Worm Fly
hair cell differentiation GO:0035315 32 0.078
forebrain neuron fate commitment GO:0021877 1 0.078
response to wounding GO:0009611 116 0.078
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.077
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.077
Mouse Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.076
Mouse Worm Fly
regulation of biological quality GO:0065008 263 0.076
Zebrafish
regulation of cell proliferation GO:0042127 37 0.075
Zebrafish Mouse Fly
axon development GO:0061564 166 0.074
regulation of cell growth GO:0001558 29 0.074
specification of symmetry GO:0009799 204 0.073
neuron projection development GO:0031175 180 0.073
semicircular canal formation GO:0060876 4 0.073
cellular nitrogen compound metabolic process GO:0034641 290 0.073
Mouse Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.072
Worm Fly
diterpenoid biosynthetic process GO:0016102 7 0.071
Zebrafish
axon extension GO:0048675 45 0.070
multi organism process GO:0051704 134 0.070
regulation of intracellular protein transport GO:0033157 3 0.070
positive regulation of bmp signaling pathway GO:0030513 10 0.069
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.069
negative regulation of chemotaxis GO:0050922 4 0.069
interaction with host GO:0051701 4 0.068
macromolecular complex subunit organization GO:0043933 74 0.066
Worm
intramembranous ossification GO:0001957 3 0.064
sympathetic nervous system development GO:0048485 3 0.064
regulation of protein localization to nucleus GO:1900180 2 0.064
regulation of organelle organization GO:0033043 29 0.064
head development GO:0060322 303 0.063
Zebrafish
regulation of cytoplasmic transport GO:1903649 4 0.063
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.063
locomotion GO:0040011 313 0.062
Zebrafish
optic placode formation involved in camera type eye formation GO:0046619 3 0.062
carbohydrate derivative biosynthetic process GO:1901137 43 0.062
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.061
blood vessel development GO:0001568 246 0.061
cellular ketone metabolic process GO:0042180 11 0.061
Zebrafish
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.061
body morphogenesis GO:0010171 16 0.061
Zebrafish
collagen metabolic process GO:0032963 2 0.061
regulation of reproductive process GO:2000241 4 0.060
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.059
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.059
positive regulation of stem cell proliferation GO:2000648 1 0.059
smooth muscle tissue development GO:0048745 1 0.058
angiogenesis GO:0001525 158 0.058
organic substance transport GO:0071702 58 0.058
optic placode formation GO:0001743 4 0.057
neuron development GO:0048666 262 0.057
Worm
nitrogen compound metabolic process GO:0006807 319 0.057
Mouse Worm Fly
regulation of developmental growth GO:0048638 38 0.057
tissue migration GO:0090130 37 0.056
neural crest cell development GO:0014032 62 0.056
Zebrafish
positive regulation of epithelial cell proliferation GO:0050679 1 0.056
chemotaxis GO:0006935 104 0.056
positive regulation of transcription dna templated GO:0045893 57 0.055
Worm Fly
face morphogenesis GO:0060325 6 0.054
secondary metabolic process GO:0019748 3 0.054
negative regulation of cellular component organization GO:0051129 16 0.054
gene expression GO:0010467 252 0.054
Zebrafish Mouse Worm Fly
determination of left right symmetry GO:0007368 179 0.054
regulation of cell size GO:0008361 29 0.054
negative regulation of striated muscle tissue development GO:0045843 2 0.053
glycoprotein biosynthetic process GO:0009101 21 0.053
neuron recognition GO:0008038 18 0.053
embryonic pattern specification GO:0009880 44 0.053
Zebrafish Worm Fly
cartilage morphogenesis GO:0060536 13 0.053
skin morphogenesis GO:0043589 7 0.052
skeletal system development GO:0001501 181 0.052
positive regulation of cell death GO:0010942 29 0.052
non canonical wnt signaling pathway GO:0035567 13 0.052
cardioblast migration GO:0003260 7 0.051
fin morphogenesis GO:0033334 53 0.051
Zebrafish
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.051
neuron projection extension GO:1990138 45 0.051
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.051
maintenance of location GO:0051235 4 0.050
ectodermal placode morphogenesis GO:0071697 32 0.050
atrial ventricular junction remodeling GO:0003294 2 0.049
negative chemotaxis GO:0050919 1 0.049
tissue remodeling GO:0048771 4 0.049
organic acid metabolic process GO:0006082 31 0.049
Zebrafish
direct ossification GO:0036072 3 0.048
negative regulation of intracellular transport GO:0032387 3 0.048
regulation of mitotic cell cycle GO:0007346 25 0.048
homeostasis of number of cells within a tissue GO:0048873 4 0.047
Zebrafish
tube morphogenesis GO:0035239 349 0.047
Zebrafish Mouse Worm
negative regulation of cellular metabolic process GO:0031324 77 0.047
Worm Fly
cellular response to endogenous stimulus GO:0071495 68 0.046
central nervous system neuron differentiation GO:0021953 74 0.046
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.046
small molecule metabolic process GO:0044281 77 0.045
Zebrafish
g1 s transition of mitotic cell cycle GO:0000082 1 0.045
positive regulation of neuron apoptotic process GO:0043525 1 0.045
epidermal cell differentiation GO:0009913 36 0.045
vasculature development GO:0001944 278 0.045
regulation of synapse assembly GO:0051963 3 0.044
establishment of localization GO:0051234 244 0.044
Worm
chromosome organization GO:0051276 31 0.044
developmental maturation GO:0021700 34 0.043
response to acid chemical GO:0001101 17 0.043
cell fate commitment GO:0045165 99 0.043
Worm
cellular response to lipopolysaccharide GO:0071222 3 0.043
peptidyl lysine acetylation GO:0018394 2 0.043
heart jogging GO:0003146 40 0.043
neuron projection morphogenesis GO:0048812 161 0.042
digestive system development GO:0055123 289 0.041
Zebrafish Mouse Worm
regulation of multicellular organismal metabolic process GO:0044246 2 0.041
rhombomere morphogenesis GO:0021593 17 0.041
heart development GO:0007507 313 0.041
Fly
central nervous system development GO:0007417 387 0.041
regulation of response to external stimulus GO:0032101 31 0.040
negative regulation of growth GO:0045926 10 0.040
posttranscriptional gene silencing GO:0016441 3 0.040
Worm
oxoacid metabolic process GO:0043436 31 0.040
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.040
negative regulation of axon guidance GO:1902668 1 0.039
otic vesicle morphogenesis GO:0071600 34 0.039
vestibular receptor cell development GO:0060118 3 0.039
cell differentiation in spinal cord GO:0021515 40 0.039
retinal rod cell development GO:0046548 4 0.039
negative regulation of cellular response to growth factor stimulus GO:0090288 9 0.039
response to fluid shear stress GO:0034405 2 0.038
positive regulation of epithelial cell migration GO:0010634 2 0.038
positive regulation of wnt signaling pathway GO:0030177 13 0.038
taxis GO:0042330 109 0.038
organic cyclic compound biosynthetic process GO:1901362 223 0.038
Mouse Worm Fly
positive regulation of transport GO:0051050 2 0.037
regulation of cellular component organization GO:0051128 86 0.037
negative regulation of nuclear division GO:0051784 3 0.037
endothelial cell fate commitment GO:0060839 3 0.037
stem cell maintenance GO:0019827 4 0.037
locus ceruleus development GO:0021703 3 0.036
negative regulation of nervous system development GO:0051961 22 0.036
sensory organ development GO:0007423 393 0.036
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.036
appendage morphogenesis GO:0035107 56 0.036
Zebrafish Fly
gene silencing by rna GO:0031047 4 0.036
Worm
regulation of apoptotic process GO:0042981 98 0.036
Mouse
regulation of cell development GO:0060284 100 0.035
Zebrafish
macromolecule localization GO:0033036 54 0.035
regulation of heart growth GO:0060420 2 0.035
bone remodeling GO:0046849 2 0.035
axon extension involved in axon guidance GO:0048846 10 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.034
sulfur compound biosynthetic process GO:0044272 9 0.034
neuron remodeling GO:0016322 1 0.034
rhombomere 5 development GO:0021571 4 0.034
hypothalamus cell differentiation GO:0021979 4 0.034
Zebrafish
rhombomere formation GO:0021594 12 0.034
negative regulation of chromosome organization GO:2001251 1 0.033
regulation of binding GO:0051098 3 0.033
exocrine system development GO:0035272 28 0.033
Fly
selective angioblast sprouting GO:0035474 5 0.033
cell recognition GO:0008037 19 0.033
phagocytosis GO:0006909 3 0.032
negative regulation of cellular component movement GO:0051271 18 0.032
Zebrafish
histone deacetylation GO:0016575 2 0.032
regulation of anatomical structure size GO:0090066 33 0.032
regulation of skeletal muscle fiber development GO:0048742 2 0.032
regulation of biomineral tissue development GO:0070167 2 0.032
negative regulation of muscle tissue development GO:1901862 2 0.032
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.032
dorsal convergence GO:0060030 14 0.031
positive regulation of glial cell differentiation GO:0045687 1 0.031
morphogenesis of a branching structure GO:0001763 21 0.031
positive regulation of striated muscle cell differentiation GO:0051155 1 0.031
nephron morphogenesis GO:0072028 2 0.031
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.031
positive regulation of nucleic acid templated transcription GO:1903508 57 0.031
Worm Fly
regulation of cell death GO:0010941 103 0.031
Mouse
regulation of biosynthetic process GO:0009889 250 0.031
Zebrafish Mouse Worm Fly
posterior lateral line neuromast primordium migration GO:0048920 12 0.031
response to endogenous stimulus GO:0009719 83 0.031
endomembrane system organization GO:0010256 13 0.031
regulation of transcription dna templated GO:0006355 213 0.031
Mouse Worm Fly
maintenance of dna repeat elements GO:0043570 2 0.030
regulation of establishment of planar polarity GO:0090175 4 0.030
positive regulation of muscle tissue development GO:1901863 1 0.030
ribosomal small subunit biogenesis GO:0042274 2 0.030
determination of heart left right asymmetry GO:0061371 117 0.030
cellular response to retinoic acid GO:0071300 1 0.029
regulation of production of molecular mediator of immune response GO:0002700 1 0.029
aorta development GO:0035904 4 0.029
eye photoreceptor cell development GO:0042462 30 0.029
regulation of programmed cell death GO:0043067 101 0.029
Mouse
negative regulation of gene expression GO:0010629 65 0.029
Worm Fly
defense response GO:0006952 47 0.029
negative regulation of cell proliferation GO:0008285 8 0.029
organelle organization GO:0006996 227 0.029
Worm
mechanoreceptor differentiation GO:0042490 37 0.028
diencephalon development GO:0021536 58 0.028
Zebrafish
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.028
Zebrafish
protein deacetylation GO:0006476 3 0.028
cellular biosynthetic process GO:0044249 286 0.028
Zebrafish Mouse Worm Fly
response to retinoic acid GO:0032526 6 0.028
retinoic acid biosynthetic process GO:0002138 6 0.028
Zebrafish
positive regulation of map kinase activity GO:0043406 3 0.028
extracellular matrix assembly GO:0085029 1 0.027
positive regulation of developmental process GO:0051094 50 0.027
Zebrafish Worm
cell cycle process GO:0022402 53 0.027
Worm
regulation of skeletal muscle tissue development GO:0048641 4 0.027
regulation of cysteine type endopeptidase activity GO:2000116 21 0.027
lateral line system development GO:0048925 76 0.027
Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.027
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.027
striated muscle cell differentiation GO:0051146 129 0.026
Zebrafish
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.026
spemann organizer formation GO:0060061 10 0.026
response to external stimulus GO:0009605 264 0.025
carbohydrate biosynthetic process GO:0016051 1 0.025
immune response GO:0006955 28 0.025
neural nucleus development GO:0048857 15 0.025
regulation of organ morphogenesis GO:2000027 35 0.025
neuron fate specification GO:0048665 20 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.025
positive regulation of striated muscle tissue development GO:0045844 1 0.025
embryonic eye morphogenesis GO:0048048 30 0.025
Zebrafish
tongue morphogenesis GO:0043587 3 0.025
negative regulation of muscle cell differentiation GO:0051148 1 0.025
vestibular receptor cell differentiation GO:0060114 3 0.024
neuroblast differentiation GO:0014016 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
Mouse Worm Fly
positive regulation of rna metabolic process GO:0051254 59 0.024
Worm Fly
regulation of organ growth GO:0046620 3 0.024
limb development GO:0060173 8 0.024
negative regulation of signal transduction GO:0009968 94 0.024
Zebrafish
convergent extension involved in axis elongation GO:0060028 26 0.024
epithelial cell migration GO:0010631 25 0.024
cell adhesion GO:0007155 40 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
Worm Fly

tcf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.078
bone disease DOID:0080001 0 0.065
disease of anatomical entity DOID:7 0 0.065
musculoskeletal system disease DOID:17 0 0.065
connective tissue disease DOID:65 0 0.065
bone development disease DOID:0080006 0 0.047
dysostosis DOID:1934 0 0.047
inherited metabolic disorder DOID:655 0 0.029
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
nervous system disease DOID:863 0 0.028
eye disease DOID:5614 0 0.028