Danio rerio

0 known processes

pcf11

cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)

(Aliases: MGC175013,zgc:92226,im:7138745,zgc:175013,wu:fc47a05,im:6912257)

pcf11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna splicing via spliceosome GO:0048024 3 0.232
regulation of mrna processing GO:0050684 3 0.198
larval development GO:0002164 2 0.177
Worm
mrna splicing via spliceosome GO:0000398 10 0.131
lipid storage GO:0019915 1 0.121
modification dependent macromolecule catabolic process GO:0043632 3 0.121
alternative mrna splicing via spliceosome GO:0000380 1 0.118
signal transduction GO:0007165 455 0.117
cellular aromatic compound metabolic process GO:0006725 295 0.108
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.107
rna biosynthetic process GO:0032774 181 0.085
aging GO:0007568 2 0.080
nuclear transport GO:0051169 4 0.079
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.079
maintenance of location GO:0051235 4 0.079
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.078
cellular macromolecule metabolic process GO:0044260 391 0.078
positive regulation of biological process GO:0048518 253 0.076
locomotion GO:0040011 313 0.074
gene expression GO:0010467 252 0.072
regulation of gene expression GO:0010468 265 0.071
regulation of erk1 and erk2 cascade GO:0070372 4 0.068
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.067
regulation of transcription dna templated GO:0006355 213 0.067
regulation of response to stimulus GO:0048583 269 0.066
multicellular organism growth GO:0035264 4 0.063
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
regulation of primary metabolic process GO:0080090 311 0.060
erk1 and erk2 cascade GO:0070371 4 0.057
rna localization GO:0006403 4 0.056
organic cyclic compound metabolic process GO:1901360 301 0.053
nitrogen compound metabolic process GO:0006807 319 0.050
regulation of metabolic process GO:0019222 359 0.050
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.049
rna processing GO:0006396 25 0.048
regulation of biosynthetic process GO:0009889 250 0.047
protein localization to nucleus GO:0034504 3 0.047
meiotic chromosome segregation GO:0045132 3 0.046
intracellular signal transduction GO:0035556 85 0.045
establishment of protein localization to organelle GO:0072594 4 0.044
muscle organ development GO:0007517 101 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
Worm
nuclear export GO:0051168 1 0.043
mitotic dna integrity checkpoint GO:0044774 4 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.042
protein targeting to nucleus GO:0044744 3 0.041
positive regulation of metabolic process GO:0009893 108 0.041
neuron differentiation GO:0030182 353 0.040
negative regulation of cellular process GO:0048523 283 0.040
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
nucleocytoplasmic transport GO:0006913 4 0.040
positive regulation of cellular process GO:0048522 201 0.039
regulation of rna biosynthetic process GO:2001141 213 0.039
regulation of signal transduction GO:0009966 225 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
nucleic acid metabolic process GO:0090304 244 0.038
organic cyclic compound biosynthetic process GO:1901362 223 0.038
nucleic acid transport GO:0050657 2 0.037
regulation of multicellular organismal development GO:2000026 223 0.037
regulation of protein catabolic process GO:0042176 1 0.037
meiotic cell cycle process GO:1903046 3 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
positive regulation of ras protein signal transduction GO:0046579 1 0.035
establishment of localization GO:0051234 244 0.035
amine metabolic process GO:0009308 2 0.035
heterocycle metabolic process GO:0046483 290 0.035
regulation of epidermis development GO:0045682 2 0.034
mitotic cell cycle process GO:1903047 48 0.034
cellular amine metabolic process GO:0044106 2 0.034
regulation of multicellular organism growth GO:0040014 4 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
protein import into nucleus GO:0006606 3 0.032
nucleic acid templated transcription GO:0097659 181 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
modification dependent protein catabolic process GO:0019941 3 0.031
regulation of rna metabolic process GO:0051252 224 0.031
meiotic nuclear division GO:0007126 4 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
positive regulation of cell cycle GO:0045787 3 0.031
locomotor rhythm GO:0045475 3 0.030
glucose homeostasis GO:0042593 1 0.030
rna metabolic process GO:0016070 219 0.030
heterocycle biosynthetic process GO:0018130 215 0.029
growth GO:0040007 174 0.029
ribonucleoside monophosphate catabolic process GO:0009158 4 0.029
regulation of circadian rhythm GO:0042752 4 0.029
nuclear import GO:0051170 3 0.028
cellular protein catabolic process GO:0044257 4 0.028
positive regulation of rna metabolic process GO:0051254 59 0.028
rna export from nucleus GO:0006405 1 0.028
negative regulation of biological process GO:0048519 304 0.028
dna templated transcription elongation GO:0006354 3 0.028
cell cycle g1 s phase transition GO:0044843 1 0.028
positive regulation of response to stimulus GO:0048584 80 0.027
phosphorus metabolic process GO:0006793 109 0.027
response to stress GO:0006950 263 0.027
positive regulation of transcription dna templated GO:0045893 57 0.027
positive regulation of catabolic process GO:0009896 4 0.027
regulation of protein targeting GO:1903533 2 0.027
regulation of photoreceptor cell differentiation GO:0046532 2 0.027
carbohydrate biosynthetic process GO:0016051 1 0.027
single organism metabolic process GO:0044710 217 0.027
regulation of protein transport GO:0051223 3 0.026
purine nucleoside monophosphate catabolic process GO:0009128 4 0.026
digestive system development GO:0055123 289 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
cognition GO:0050890 1 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
regulation of reproductive process GO:2000241 4 0.025
cellular carbohydrate metabolic process GO:0044262 4 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
transcription dna templated GO:0006351 181 0.024
regulation of signaling GO:0023051 235 0.024
biosynthetic process GO:0009058 294 0.024
positive regulation of transport GO:0051050 2 0.024
response to uv GO:0009411 3 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
regulation of cell communication GO:0010646 232 0.024
endocrine process GO:0050886 2 0.024
regulation of cellular protein catabolic process GO:1903362 1 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
regulation of carbohydrate metabolic process GO:0006109 4 0.024
protein import GO:0017038 3 0.024
digestive tract development GO:0048565 265 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
macromolecular complex disassembly GO:0032984 1 0.023
neuroblast proliferation GO:0007405 2 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
cellular ketone metabolic process GO:0042180 11 0.023
positive regulation of rna biosynthetic process GO:1902680 57 0.022
entrainment of circadian clock GO:0009649 2 0.022
transport GO:0006810 220 0.022
mrna processing GO:0006397 14 0.022
spindle assembly GO:0051225 2 0.022
cellular component disassembly GO:0022411 1 0.022
cellular response to radiation GO:0071478 4 0.022
cell death GO:0008219 121 0.022
Worm
stem cell proliferation GO:0072089 4 0.022
mitochondrion organization GO:0007005 4 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
generation of neurons GO:0048699 385 0.021
single organism nuclear import GO:1902593 3 0.021
positive regulation of nucleic acid templated transcription GO:1903508 57 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
entrainment of circadian clock by photoperiod GO:0043153 1 0.021
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.021
intracellular estrogen receptor signaling pathway GO:0030520 3 0.020
circadian rhythm GO:0007623 19 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
rna splicing GO:0008380 16 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.020
female gonad development GO:0008585 4 0.020
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.020
cell morphogenesis GO:0000902 289 0.020
neuron development GO:0048666 262 0.020
gtp metabolic process GO:0046039 4 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
reproductive process GO:0022414 40 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
single organism organelle organization GO:1902589 199 0.019
adult behavior GO:0030534 2 0.018
system process GO:0003008 185 0.018
response to drug GO:0042493 3 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
negative regulation of kinase activity GO:0033673 4 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
mitotic cell cycle GO:0000278 64 0.018
regulation of sodium ion transport GO:0002028 2 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
response to chemical GO:0042221 320 0.018
steroid hormone secretion GO:0035929 1 0.018
meiosis i GO:0007127 1 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
protein complex disassembly GO:0043241 1 0.017
regulation of synapse assembly GO:0051963 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
circulatory system process GO:0003013 87 0.017
organic substance biosynthetic process GO:1901576 289 0.017
endocrine hormone secretion GO:0060986 2 0.017
interspecies interaction between organisms GO:0044419 4 0.017
regulation of dna templated transcription elongation GO:0032784 3 0.017
regulation of growth rate GO:0040009 1 0.017
golgi vesicle transport GO:0048193 3 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
response to organic substance GO:0010033 153 0.017
ovulation cycle process GO:0022602 2 0.017
carbohydrate homeostasis GO:0033500 1 0.017
positive regulation of cell communication GO:0010647 56 0.017
cellular biosynthetic process GO:0044249 286 0.017
nucleobase containing compound transport GO:0015931 2 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
regulation of rna splicing GO:0043484 8 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
cellular response to stress GO:0033554 62 0.016
cytokinesis GO:0000910 3 0.016
atp catabolic process GO:0006200 4 0.016
cell cycle process GO:0022402 53 0.016
homeostatic process GO:0042592 142 0.016
positive regulation of signal transduction GO:0009967 56 0.016
muscle structure development GO:0061061 196 0.016
spliceosomal complex assembly GO:0000245 1 0.016
protein polymerization GO:0051258 4 0.016
regulation of cell cycle GO:0051726 52 0.016
multi organism process GO:0051704 134 0.016
rhombomere 5 development GO:0021571 4 0.016
skeletal muscle tissue development GO:0007519 67 0.016
female sex differentiation GO:0046660 4 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
response to wounding GO:0009611 116 0.016
skeletal muscle organ development GO:0060538 78 0.016
signal transduction in absence of ligand GO:0038034 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
single organism transport GO:0044765 206 0.016
peptidyl serine modification GO:0018209 2 0.016
regulation of binding GO:0051098 3 0.016
cellular component movement GO:0006928 335 0.016
gtp catabolic process GO:0006184 2 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
establishment of rna localization GO:0051236 3 0.015
regulation of programmed cell death GO:0043067 101 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
regulation of cell activation GO:0050865 1 0.015
phagocytosis GO:0006909 3 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
muscle tissue development GO:0060537 110 0.015
regulation of protein polymerization GO:0032271 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
regulation of tube size GO:0035150 2 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
mitotic g2 m transition checkpoint GO:0044818 3 0.015
stem cell division GO:0017145 1 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
mononuclear cell proliferation GO:0032943 1 0.015
hemopoiesis GO:0030097 183 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of chromosome segregation GO:0051983 1 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
positive regulation of leukocyte differentiation GO:1902107 1 0.015
somatic muscle development GO:0007525 4 0.014
multi organism cellular process GO:0044764 2 0.014
viral process GO:0016032 1 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
hormone transport GO:0009914 2 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of developmental process GO:0050793 247 0.014
positive regulation of gene expression GO:0010628 71 0.014
oocyte maturation GO:0001556 4 0.014
ovulation cycle GO:0042698 2 0.014
response to abiotic stimulus GO:0009628 122 0.014
blood vessel development GO:0001568 246 0.014
regulation of cell shape GO:0008360 1 0.014
cellular biogenic amine metabolic process GO:0006576 2 0.014
positive regulation of dna templated transcription elongation GO:0032786 1 0.014
single organism localization GO:1902578 225 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
positive regulation of cell division GO:0051781 2 0.014
response to alkaloid GO:0043279 2 0.014
rna transport GO:0050658 2 0.014
brain development GO:0007420 293 0.014
hormone secretion GO:0046879 2 0.013
regulation of endocrine process GO:0044060 2 0.013
muscle cell migration GO:0014812 4 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
angiogenesis GO:0001525 158 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
organelle organization GO:0006996 227 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
regionalization GO:0003002 274 0.013
protein dephosphorylation GO:0006470 3 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
cell projection organization GO:0030030 284 0.013
response to hydrogen peroxide GO:0042542 3 0.013
alcohol biosynthetic process GO:0046165 2 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
rhombomere 6 development GO:0021572 4 0.013
circadian regulation of gene expression GO:0032922 8 0.013
response to nutrient GO:0007584 3 0.013
regulation of synapse organization GO:0050807 3 0.013
immune system process GO:0002376 241 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
er to golgi vesicle mediated transport GO:0006888 1 0.013
nuclear division GO:0000280 23 0.013
energy reserve metabolic process GO:0006112 2 0.013
tissue remodeling GO:0048771 4 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
response to corticosteroid GO:0031960 1 0.012
skin development GO:0043588 54 0.012
programmed cell death GO:0012501 119 0.012
Worm
mesenchymal cell differentiation GO:0048762 87 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
central nervous system development GO:0007417 387 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
regulation of wound healing GO:0061041 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
mrna transport GO:0051028 2 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of cell projection assembly GO:0060491 4 0.012
immune system development GO:0002520 191 0.012
leukocyte proliferation GO:0070661 1 0.012
centrosome organization GO:0051297 1 0.012
double strand break repair GO:0006302 3 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of hormone secretion GO:0046883 2 0.012
protein acylation GO:0043543 3 0.012
germ line stem cell maintenance GO:0030718 2 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
cell part morphogenesis GO:0032990 246 0.012
stem cell maintenance GO:0019827 4 0.012
regulation of muscle contraction GO:0006937 3 0.012
single organism reproductive process GO:0044702 40 0.012
mesenchymal cell development GO:0014031 78 0.012
negative regulation of secretion GO:0051048 2 0.012
mrna export from nucleus GO:0006406 1 0.012
regulation of cell death GO:0010941 103 0.012
cellular protein modification process GO:0006464 100 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
cellular response to nutrient levels GO:0031669 2 0.011
blood vessel morphogenesis GO:0048514 216 0.011
regulation of blood pressure GO:0008217 1 0.011
recombinational repair GO:0000725 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
vacuolar transport GO:0007034 2 0.011
mitochondrial transport GO:0006839 2 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
protein localization to plasma membrane GO:0072659 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
urogenital system development GO:0001655 97 0.011
macroautophagy GO:0016236 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
small molecule metabolic process GO:0044281 77 0.011
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
actin filament polymerization GO:0030041 2 0.011
localization of cell GO:0051674 244 0.011
epithelial cell differentiation GO:0030855 116 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
mapk cascade GO:0000165 18 0.011
phosphorylation GO:0016310 69 0.011
cellular response to starvation GO:0009267 1 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
rhombomere formation GO:0021594 12 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
response to ketone GO:1901654 1 0.011
regulation of jak stat cascade GO:0046425 3 0.011
positive regulation of neuron death GO:1901216 1 0.011
protein metabolic process GO:0019538 183 0.011
protein secretion GO:0009306 1 0.011
rna splicing via transesterification reactions GO:0000375 10 0.011
regulation of blood vessel size GO:0050880 2 0.011
cellular component assembly GO:0022607 170 0.011
female meiotic division GO:0007143 2 0.011
cell projection morphogenesis GO:0048858 244 0.011
tube morphogenesis GO:0035239 349 0.010
regulation of inflammatory response GO:0050727 2 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of dna replication GO:0006275 3 0.010
behavior GO:0007610 74 0.010
regulation of lipid transport GO:0032368 4 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
cellular protein complex disassembly GO:0043624 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
antimicrobial humoral response GO:0019730 2 0.010
regulation of biological quality GO:0065008 263 0.010
neurotransmitter transport GO:0006836 2 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
positive regulation of signaling GO:0023056 56 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
negative regulation of cell cycle GO:0045786 14 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
cellular response to dna damage stimulus GO:0006974 24 0.010
mechanosensory behavior GO:0007638 2 0.010
intracellular transport GO:0046907 32 0.010
peptidyl threonine modification GO:0018210 1 0.010
response to external stimulus GO:0009605 264 0.010
forebrain cell migration GO:0021885 1 0.010
oxoacid metabolic process GO:0043436 31 0.010
protein modification process GO:0036211 100 0.010
mrna stabilization GO:0048255 4 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
translational initiation GO:0006413 3 0.010
negative regulation of metabolic process GO:0009892 86 0.010

pcf11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.011