Danio rerio

103 known processes

six1a

sine oculis homeobox homolog 1a

(Aliases: zgc:92332,six1b,six2)

six1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of epithelial cell proliferation GO:0050678 3 0.746
Mouse
regulation of primary metabolic process GO:0080090 311 0.743
cellular macromolecule biosynthetic process GO:0034645 224 0.684
muscle structure development GO:0061061 196 0.631
embryonic organ morphogenesis GO:0048562 274 0.600
Zebrafish Mouse
regionalization GO:0003002 274 0.568
Mouse
cellular component movement GO:0006928 335 0.555
Mouse Fly
establishment of localization GO:0051234 244 0.487
regulation of macromolecule metabolic process GO:0060255 317 0.480
regulation of cellular metabolic process GO:0031323 320 0.480
central nervous system development GO:0007417 387 0.479
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.477
positive regulation of rna biosynthetic process GO:1902680 57 0.465
Human Mouse Fly
signal transduction GO:0007165 455 0.459
cellular nitrogen compound biosynthetic process GO:0044271 218 0.458
regulation of gene expression GO:0010468 265 0.433
regulation of macromolecule biosynthetic process GO:0010556 225 0.424
gene expression GO:0010467 252 0.422
regulation of rna metabolic process GO:0051252 224 0.417
cellular aromatic compound metabolic process GO:0006725 295 0.399
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.376
epithelial tube morphogenesis GO:0060562 148 0.375
Mouse
locomotion GO:0040011 313 0.367
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.360
aromatic compound biosynthetic process GO:0019438 217 0.320
cellular biosynthetic process GO:0044249 286 0.307
digestive tract development GO:0048565 265 0.306
Zebrafish
tube morphogenesis GO:0035239 349 0.302
Mouse
renal system development GO:0072001 94 0.252
Zebrafish Mouse
sensory organ development GO:0007423 393 0.251
heterocycle biosynthetic process GO:0018130 215 0.250
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.248
regulation of nitrogen compound metabolic process GO:0051171 251 0.242
head development GO:0060322 303 0.236
Zebrafish
cellular component morphogenesis GO:0032989 336 0.235
nucleic acid templated transcription GO:0097659 181 0.234
retina development in camera type eye GO:0060041 146 0.232
embryonic heart tube development GO:0035050 133 0.229
embryonic organ development GO:0048568 381 0.224
Zebrafish Mouse
cell fate commitment GO:0045165 99 0.223
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.221
Mouse
digestive tract morphogenesis GO:0048546 231 0.217
chordate embryonic development GO:0043009 271 0.213
Mouse
skeletal system development GO:0001501 181 0.209
Mouse
heart morphogenesis GO:0003007 156 0.197
Mouse
axon development GO:0061564 166 0.195
neuron differentiation GO:0030182 353 0.187
rna biosynthetic process GO:0032774 181 0.183
striated muscle tissue development GO:0014706 110 0.175
rna metabolic process GO:0016070 219 0.175
transport GO:0006810 220 0.172
cellular macromolecule metabolic process GO:0044260 391 0.171
cytokinesis GO:0000910 3 0.166
transcription from rna polymerase ii promoter GO:0006366 80 0.163
gastrulation GO:0007369 208 0.163
regulation of synapse assembly GO:0051963 3 0.160
Mouse
heart development GO:0007507 313 0.160
Mouse
regulation of metabolic process GO:0019222 359 0.160
biosynthetic process GO:0009058 294 0.159
neuron development GO:0048666 262 0.156
Zebrafish
regulation of synapse organization GO:0050807 3 0.156
Mouse
cell fate specification GO:0001708 68 0.154
Mouse
negative regulation of biological process GO:0048519 304 0.153
Mouse
generation of neurons GO:0048699 385 0.152
digestive system development GO:0055123 289 0.145
Zebrafish
regulation of cell communication GO:0010646 232 0.145
striated muscle cell differentiation GO:0051146 129 0.141
embryonic skeletal system development GO:0048706 97 0.141
Mouse
regulation of response to stimulus GO:0048583 269 0.140
nitrogen compound metabolic process GO:0006807 319 0.140
regulation of nervous system development GO:0051960 90 0.139
muscle organ development GO:0007517 101 0.136
localization of cell GO:0051674 244 0.135
Mouse Fly
brain development GO:0007420 293 0.134
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.134
Human Mouse Fly
regulation of transcription dna templated GO:0006355 213 0.130
positive regulation of biological process GO:0048518 253 0.130
Human Mouse Fly
connective tissue development GO:0061448 99 0.126
positive regulation of gene expression GO:0010628 71 0.125
Human Mouse Fly
neuron projection guidance GO:0097485 86 0.122
chemotaxis GO:0006935 104 0.119
regulation of biosynthetic process GO:0009889 250 0.119
cell surface receptor signaling pathway GO:0007166 325 0.117
fin development GO:0033333 77 0.117
cellular component assembly GO:0022607 170 0.116
Mouse
axon guidance GO:0007411 86 0.116
posterior lateral line development GO:0048916 38 0.114
appendage development GO:0048736 80 0.113
cell morphogenesis GO:0000902 289 0.111
hindbrain development GO:0030902 91 0.111
positive regulation of nucleic acid templated transcription GO:1903508 57 0.110
Human Mouse Fly
cell migration GO:0016477 237 0.110
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.109
embryonic epithelial tube formation GO:0001838 17 0.108
Mouse
regulation of signal transduction GO:0009966 225 0.107
axonogenesis GO:0007409 152 0.106
response to organic substance GO:0010033 153 0.104
cell projection organization GO:0030030 284 0.101
regulation of biological quality GO:0065008 263 0.100
Mouse
eye morphogenesis GO:0048592 144 0.100
Zebrafish Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.099
Mouse
macromolecule biosynthetic process GO:0009059 227 0.098
positive regulation of transport GO:0051050 2 0.096
positive regulation of metabolic process GO:0009893 108 0.095
Human Mouse Fly
membrane fusion GO:0061025 2 0.093
primary neural tube formation GO:0014020 1 0.092
sensory organ morphogenesis GO:0090596 200 0.092
Zebrafish Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.092
epithelial tube formation GO:0072175 19 0.092
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.091
otic vesicle development GO:0071599 42 0.091
Mouse
camera type eye morphogenesis GO:0048593 108 0.091
Zebrafish
cell motility GO:0048870 244 0.091
Mouse Fly
cell part morphogenesis GO:0032990 246 0.087
positive regulation of cellular component biogenesis GO:0044089 3 0.086
eye development GO:0001654 277 0.084
Zebrafish Fly
nucleobase containing compound metabolic process GO:0006139 274 0.083
renal tubule morphogenesis GO:0061333 1 0.083
Mouse
forebrain cell migration GO:0021885 1 0.082
cellular component biogenesis GO:0044085 178 0.082
Mouse
system process GO:0003008 185 0.080
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.080
Mouse
response to chemical GO:0042221 320 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.078
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.077
mesoderm development GO:0007498 88 0.076
regulation of cellular biosynthetic process GO:0031326 245 0.076
cellular nitrogen compound metabolic process GO:0034641 290 0.076
neuron projection development GO:0031175 180 0.075
actin filament based process GO:0030029 64 0.075
aging GO:0007568 2 0.075
compound eye development GO:0048749 2 0.075
Fly
regulation of cell development GO:0060284 100 0.074
larval development GO:0002164 2 0.073
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.073
Mouse
muscle cell development GO:0055001 115 0.072
lateral line development GO:0048882 66 0.070
appendage morphogenesis GO:0035107 56 0.070
extraocular skeletal muscle development GO:0002074 3 0.069
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.069
Human Mouse Fly
fin morphogenesis GO:0033334 53 0.069
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.066
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.066
cartilage development GO:0051216 96 0.066
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.066
negative regulation of developmental process GO:0051093 65 0.066
Mouse
blood vessel development GO:0001568 246 0.066
Mouse
positive regulation of cellular process GO:0048522 201 0.065
Human Mouse Fly
stem cell maintenance GO:0019827 4 0.064
single organism reproductive process GO:0044702 40 0.064
Fly
nucleic acid metabolic process GO:0090304 244 0.063
neurotransmitter transport GO:0006836 2 0.062
negative regulation of cellular biosynthetic process GO:0031327 55 0.062
Mouse
regulation of skeletal muscle tissue development GO:0048641 4 0.062
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.061
skeletal muscle organ development GO:0060538 78 0.060
regulation of cell differentiation GO:0045595 142 0.057
regulation of signaling GO:0023051 235 0.057
cardiac atrium development GO:0003230 4 0.057
positive regulation of transcription dna templated GO:0045893 57 0.057
Human Mouse Fly
specification of symmetry GO:0009799 204 0.056
cell projection morphogenesis GO:0048858 244 0.056
glial cell migration GO:0008347 3 0.056
Fly
somatic muscle development GO:0007525 4 0.055
ear development GO:0043583 127 0.054
regulation of apoptotic process GO:0042981 98 0.054
Mouse
pectoral fin development GO:0033339 50 0.054
dorsal ventral pattern formation GO:0009953 125 0.053
camera type eye development GO:0043010 222 0.053
Zebrafish
response to external stimulus GO:0009605 264 0.052
Fly
skeletal system morphogenesis GO:0048705 102 0.051
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.051
Human Mouse Fly
endocrine system development GO:0035270 65 0.051
Zebrafish Mouse Fly
epithelial cell differentiation GO:0030855 116 0.050
Mouse
anterior posterior pattern specification GO:0009952 152 0.049
negative regulation of response to stimulus GO:0048585 104 0.049
mechanosensory lateral line system development GO:0048881 49 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.048
Human Mouse Fly
mechanoreceptor differentiation GO:0042490 37 0.048
neuron projection morphogenesis GO:0048812 161 0.048
skeletal muscle tissue development GO:0007519 67 0.048
organ formation GO:0048645 17 0.047
Mouse
olfactory bulb development GO:0021772 4 0.046
protein metabolic process GO:0019538 183 0.046
heart contraction GO:0060047 71 0.046
heterocycle metabolic process GO:0046483 290 0.046
olfactory lobe development GO:0021988 4 0.046
embryonic skeletal system morphogenesis GO:0048704 93 0.046
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.045
Mouse
peripheral nervous system neuron differentiation GO:0048934 28 0.045
Zebrafish
post embryonic organ development GO:0048569 4 0.045
neural tube development GO:0021915 62 0.045
single organism membrane fusion GO:0044801 2 0.045
taxis GO:0042330 109 0.044
facial nerve development GO:0021561 3 0.044
Mouse
heart looping GO:0001947 94 0.044
urogenital system development GO:0001655 97 0.044
Zebrafish Mouse
ear morphogenesis GO:0042471 64 0.044
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.044
Human Mouse Fly
growth GO:0040007 174 0.043
Zebrafish Mouse
phagocytosis GO:0006909 3 0.043
forebrain development GO:0030900 96 0.041
Zebrafish
apoptotic process GO:0006915 116 0.041
Mouse
neuron neuron synaptic transmission GO:0007270 1 0.041
embryonic cranial skeleton morphogenesis GO:0048701 90 0.041
Mouse
determination of heart left right asymmetry GO:0061371 117 0.041
stem cell differentiation GO:0048863 117 0.041
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.040
regulation of metal ion transport GO:0010959 4 0.039
muscle cell differentiation GO:0042692 139 0.039
medulla oblongata development GO:0021550 4 0.039
cytoskeleton organization GO:0007010 96 0.039
cell migration involved in vasculogenesis GO:0035441 1 0.038
lateral line system development GO:0048925 76 0.038
regulation of mechanoreceptor differentiation GO:0045631 1 0.037
regulation of inner ear receptor cell differentiation GO:2000980 1 0.037
immune system process GO:0002376 241 0.037
Mouse
cardiac atrium morphogenesis GO:0003209 2 0.037
response to stress GO:0006950 263 0.036
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 3 0.036
negative regulation of metabolic process GO:0009892 86 0.036
Mouse
kidney development GO:0001822 92 0.036
Zebrafish Mouse
negative regulation of epithelial cell migration GO:0010633 1 0.036
transcription dna templated GO:0006351 181 0.036
retina morphogenesis in camera type eye GO:0060042 79 0.035
negative regulation of signaling GO:0023057 96 0.035
single organism transport GO:0044765 206 0.035
regulation of myotube differentiation GO:0010830 2 0.034
embryonic pectoral fin morphogenesis GO:0035118 24 0.034
establishment or maintenance of cell polarity GO:0007163 29 0.034
positive regulation of programmed cell death GO:0043068 29 0.034
morphogenesis of an epithelium GO:0002009 333 0.034
Mouse
immune system development GO:0002520 191 0.034
Mouse
negative regulation of cellular process GO:0048523 283 0.033
Mouse
neural tube formation GO:0001841 16 0.033
cell proliferation GO:0008283 80 0.033
hepaticobiliary system development GO:0061008 98 0.033
positive regulation of epithelial cell proliferation GO:0050679 1 0.033
cranial ganglion development GO:0061550 3 0.033
Mouse
response to other organism GO:0051707 97 0.032
pectoral fin morphogenesis GO:0035138 29 0.032
regulation of developmental process GO:0050793 247 0.032
stem cell proliferation GO:0072089 4 0.031
Mouse
myotube differentiation GO:0014902 45 0.031
posterior lateral line system development GO:0048915 46 0.031
pancreas development GO:0031016 84 0.031
inner ear morphogenesis GO:0042472 63 0.031
Mouse
macromolecular complex assembly GO:0065003 35 0.031
negative regulation of cell communication GO:0010648 96 0.030
inner ear development GO:0048839 126 0.030
regulation of wnt signaling pathway GO:0030111 53 0.030
multi organism process GO:0051704 134 0.030
Fly
neurotransmitter secretion GO:0007269 2 0.029
gland development GO:0048732 143 0.029
Zebrafish Mouse Fly
erythrocyte homeostasis GO:0034101 55 0.029
determination of left right symmetry GO:0007368 179 0.029
gliogenesis GO:0042063 45 0.029
Fly
sexual reproduction GO:0019953 36 0.028
Fly
negative regulation of transcription dna templated GO:0045892 45 0.028
Mouse
cellular macromolecular complex assembly GO:0034622 24 0.028
negative regulation of apoptotic process GO:0043066 55 0.028
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.028
mechanosensory behavior GO:0007638 2 0.028
determination of bilateral symmetry GO:0009855 204 0.028
regulation of programmed cell death GO:0043067 101 0.027
Mouse
lipid storage GO:0019915 1 0.027
negative regulation of cellular metabolic process GO:0031324 77 0.027
Mouse
multicellular organism growth GO:0035264 4 0.027
epithelial cell morphogenesis GO:0003382 2 0.027
hemopoiesis GO:0030097 183 0.027
cardiocyte differentiation GO:0035051 44 0.026
myotube cell development GO:0014904 35 0.026
central nervous system neuron differentiation GO:0021953 74 0.026
liver development GO:0001889 96 0.026
sensory system development GO:0048880 76 0.026
organelle fusion GO:0048284 3 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.026
Mouse
regulation of cell death GO:0010941 103 0.026
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.026
Human Mouse Fly
neuroblast proliferation GO:0007405 2 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
metal ion transport GO:0030001 58 0.025
nephron epithelium morphogenesis GO:0072088 1 0.025
Mouse
neural nucleus development GO:0048857 15 0.025
nerve development GO:0021675 45 0.025
Mouse
negative regulation of gliogenesis GO:0014014 1 0.025
ectodermal placode development GO:0071696 37 0.024
Mouse Fly
positive regulation of response to stimulus GO:0048584 80 0.024
regulation of protein transport GO:0051223 3 0.023
somatic stem cell maintenance GO:0035019 1 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
Human Mouse Fly
reflex GO:0060004 2 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
Mouse
response to wounding GO:0009611 116 0.022
Zebrafish
pharyngeal muscle development GO:0043282 4 0.022
Zebrafish
startle response GO:0001964 4 0.022
cellular protein metabolic process GO:0044267 129 0.021
response to endogenous stimulus GO:0009719 83 0.021
peripheral nervous system development GO:0007422 55 0.021
Zebrafish
inner ear receptor cell fate commitment GO:0060120 4 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.021
mesenchyme development GO:0060485 127 0.021
Mouse
exocrine system development GO:0035272 28 0.021
tube closure GO:0060606 1 0.020
cellular protein complex assembly GO:0043623 19 0.020
single organism organelle organization GO:1902589 199 0.020
regulation of embryonic development GO:0045995 47 0.020
Mouse
adult behavior GO:0030534 2 0.020
single organism cell adhesion GO:0098602 29 0.020
regulation of multicellular organismal process GO:0051239 277 0.019
cellular response to organic substance GO:0071310 105 0.019
segmentation GO:0035282 97 0.019
auditory receptor cell fate commitment GO:0009912 4 0.019
response to oxygen containing compound GO:1901700 55 0.019
establishment of localization in cell GO:0051649 77 0.019
regulation of axon extension GO:0030516 24 0.019
protein stabilization GO:0050821 2 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
positive regulation of biosynthetic process GO:0009891 68 0.019
Human Mouse Fly
antimicrobial humoral response GO:0019730 2 0.019
death GO:0016265 121 0.019
Mouse
blood vessel morphogenesis GO:0048514 216 0.019
Mouse
otic vesicle morphogenesis GO:0071600 34 0.019
smooth muscle contraction GO:0006939 2 0.019
regulation of cell shape GO:0008360 1 0.019
regulation of skeletal muscle cell differentiation GO:2001014 1 0.018
Mouse
oxoacid metabolic process GO:0043436 31 0.018
cellular response to endogenous stimulus GO:0071495 68 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
Mouse
cardiac muscle tissue development GO:0048738 48 0.018
regulation of cellular component organization GO:0051128 86 0.018
Mouse
sensory perception of pain GO:0019233 1 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
single organism localization GO:1902578 225 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.018
regulation of synapse structure and activity GO:0050803 5 0.018
Mouse
cellular amino acid metabolic process GO:0006520 7 0.017
cellular protein catabolic process GO:0044257 4 0.017
positive regulation of secretion GO:0051047 1 0.017
positive regulation of reproductive process GO:2000243 2 0.017
somite development GO:0061053 96 0.017
Mouse
protein complex biogenesis GO:0070271 30 0.017
olfactory bulb axon guidance GO:0071678 3 0.017
mesodermal cell differentiation GO:0048333 21 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
organelle organization GO:0006996 227 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cranial nerve development GO:0021545 42 0.016
Mouse
determination of ventral identity GO:0048264 21 0.016
myeloid cell differentiation GO:0030099 86 0.016
inner ear receptor cell differentiation GO:0060113 29 0.016
single organism cellular localization GO:1902580 46 0.016
somitogenesis GO:0001756 87 0.016
bmp signaling pathway GO:0030509 52 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
regulation of extent of cell growth GO:0061387 29 0.016
positive regulation of striated muscle tissue development GO:0045844 1 0.016
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.016
Mouse
mesodermal cell fate commitment GO:0001710 14 0.016
heart process GO:0003015 71 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
response to growth factor GO:0070848 39 0.016
muscle cell migration GO:0014812 4 0.016
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.015
Mouse
regulation of protein complex assembly GO:0043254 3 0.015
regulation of mrna processing GO:0050684 3 0.015
myofibril assembly GO:0030239 48 0.015
ventricular system development GO:0021591 12 0.015
vasculature development GO:0001944 278 0.015
Mouse
innervation GO:0060384 3 0.015
actomyosin structure organization GO:0031032 53 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
Mouse
regulation of multicellular organismal development GO:2000026 223 0.015
homeostatic process GO:0042592 142 0.015
embryonic appendage morphogenesis GO:0035113 30 0.015
adenohypophysis development GO:0021984 15 0.015
Zebrafish
regulation of neuronal synaptic plasticity GO:0048168 1 0.015
negative regulation of signal transduction GO:0009968 94 0.014
cell growth GO:0016049 57 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
regulation of binding GO:0051098 3 0.014
protein homooligomerization GO:0051260 3 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
Mouse
negative regulation of catalytic activity GO:0043086 21 0.014
cellular response to hypoxia GO:0071456 1 0.014
maintenance of location GO:0051235 4 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.014
negative regulation of protein kinase b signaling GO:0051898 2 0.014
response to hormone GO:0009725 48 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
cognition GO:0050890 1 0.014
trigeminal nerve development GO:0021559 3 0.014
gland morphogenesis GO:0022612 13 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
embryonic viscerocranium morphogenesis GO:0048703 52 0.014
palate development GO:0060021 8 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
positive regulation of cell cycle GO:0045787 3 0.014
cellular response to hormone stimulus GO:0032870 39 0.014
hard palate development GO:0060022 4 0.013
locomotory behavior GO:0007626 34 0.013
cellular response to external stimulus GO:0071496 2 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
venous blood vessel development GO:0060841 9 0.013
myotome development GO:0061055 1 0.013
Mouse
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
tube formation GO:0035148 25 0.013
Mouse
macromolecular complex subunit organization GO:0043933 74 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
cytokinetic process GO:0032506 2 0.013
lateral inhibition GO:0046331 1 0.013
mitochondrion organization GO:0007005 4 0.013
body morphogenesis GO:0010171 16 0.013
reproduction GO:0000003 40 0.013
Fly
synaptic target recognition GO:0008039 1 0.013
response to external biotic stimulus GO:0043207 97 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
Mouse
gtp metabolic process GO:0046039 4 0.013
positive regulation of epithelial cell differentiation GO:0030858 2 0.013
regulation of cartilage development GO:0061035 7 0.013
macromolecule localization GO:0033036 54 0.012
Human Mouse
developmental maturation GO:0021700 34 0.012
brain morphogenesis GO:0048854 18 0.012
regulation of organ growth GO:0046620 3 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
exocrine pancreas development GO:0031017 28 0.012
neuron projection extension GO:1990138 45 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
Mouse
muscle fiber development GO:0048747 52 0.012
organelle localization GO:0051640 49 0.012
wnt signaling pathway GO:0016055 80 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
regulation of chondrocyte differentiation GO:0032330 1 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
protein homotrimerization GO:0070207 1 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.012
actin filament organization GO:0007015 15 0.012
vestibular receptor cell development GO:0060118 3 0.012
negative regulation of histone modification GO:0031057 1 0.012
histone demethylation GO:0016577 2 0.012
blood circulation GO:0008015 87 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.012
cardiac muscle tissue morphogenesis GO:0055008 7 0.012
formation of primary germ layer GO:0001704 62 0.012
lamellipodium assembly GO:0030032 1 0.012
positive regulation of signal transduction GO:0009967 56 0.012
negative regulation of rna metabolic process GO:0051253 48 0.011
Mouse
vesicle mediated transport GO:0016192 22 0.011
negative regulation of axon guidance GO:1902668 1 0.011
amine metabolic process GO:0009308 2 0.011
convergent extension GO:0060026 118 0.011
synapse organization GO:0050808 21 0.011
Mouse
striated muscle cell proliferation GO:0014855 7 0.011
neurological system process GO:0050877 62 0.011
Mouse
myeloid cell development GO:0061515 32 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
nuclear transport GO:0051169 4 0.011
cell substrate adhesion GO:0031589 4 0.011
nephron epithelium development GO:0072009 16 0.011
Mouse
hair cell differentiation GO:0035315 32 0.011
cellular response to stress GO:0033554 62 0.011
regulation of transporter activity GO:0032409 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
mesenchymal cell development GO:0014031 78 0.011
regulation of heart growth GO:0060420 2 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
reproductive process GO:0022414 40 0.011
Fly
regulation of neurogenesis GO:0050767 87 0.011
neuron fate specification GO:0048665 20 0.011
Mouse
regulation of organelle assembly GO:1902115 4 0.011
posterior lateral line neuromast primordium migration GO:0048920 12 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
regulation of cell proliferation GO:0042127 37 0.011
synaptic vesicle localization GO:0097479 1 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
cardiac chamber development GO:0003205 19 0.011
response to drug GO:0042493 3 0.011

six1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
Human
musculoskeletal system disease DOID:17 0 0.043
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
muscle tissue disease DOID:66 0 0.024
nervous system disease DOID:863 0 0.011
Human