Danio rerio

67 known processes

fev

FEV (ETS oncogene family)

(Aliases: pet1,zgc:158720)

fev biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.474
monoamine transport GO:0015844 1 0.310
regulation of cell differentiation GO:0045595 142 0.291
hemopoiesis GO:0030097 183 0.289
blood vessel development GO:0001568 246 0.216
single organism biosynthetic process GO:0044711 71 0.170
sleep GO:0030431 1 0.170
blood vessel morphogenesis GO:0048514 216 0.160
circadian sleep wake cycle GO:0042745 2 0.159
vasculature development GO:0001944 278 0.158
myeloid cell differentiation GO:0030099 86 0.138
intestinal absorption GO:0050892 2 0.127
cellular amine metabolic process GO:0044106 2 0.127
cellular macromolecule biosynthetic process GO:0034645 224 0.123
circadian sleep wake cycle process GO:0022410 2 0.115
sprouting angiogenesis GO:0002040 53 0.111
amine metabolic process GO:0009308 2 0.108
single organism localization GO:1902578 225 0.107
erythrocyte homeostasis GO:0034101 55 0.101
cell substrate adhesion GO:0031589 4 0.095
ion transport GO:0006811 114 0.095
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.093
hypothalamus cell differentiation GO:0021979 4 0.084
organic cyclic compound metabolic process GO:1901360 301 0.082
heterocycle biosynthetic process GO:0018130 215 0.081
stem cell differentiation GO:0048863 117 0.080
catecholamine metabolic process GO:0006584 2 0.080
immune system process GO:0002376 241 0.076
membrane hyperpolarization GO:0060081 1 0.075
catechol containing compound metabolic process GO:0009712 2 0.075
aromatic compound biosynthetic process GO:0019438 217 0.070
lipid catabolic process GO:0016042 4 0.069
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.067
regulation of cellular biosynthetic process GO:0031326 245 0.066
smooth muscle contraction GO:0006939 2 0.064
organic acid metabolic process GO:0006082 31 0.064
negative regulation of signaling GO:0023057 96 0.060
mononuclear cell proliferation GO:0032943 1 0.060
leukocyte proliferation GO:0070661 1 0.059
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.058
cellular biogenic amine metabolic process GO:0006576 2 0.058
regulation of multicellular organismal development GO:2000026 223 0.056
phagocytosis GO:0006909 3 0.056
regulation of cellular ketone metabolic process GO:0010565 7 0.053
regulation of postsynaptic membrane potential GO:0060078 1 0.053
small molecule metabolic process GO:0044281 77 0.053
iron ion homeostasis GO:0055072 4 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
regulation of primary metabolic process GO:0080090 311 0.051
autophagy GO:0006914 4 0.051
immune system development GO:0002520 191 0.050
xanthophore differentiation GO:0050936 3 0.050
mesenchyme development GO:0060485 127 0.049
heart process GO:0003015 71 0.047
organonitrogen compound biosynthetic process GO:1901566 47 0.047
single organism metabolic process GO:0044710 217 0.047
regulation of metal ion transport GO:0010959 4 0.047
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.046
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
cellular response to oxygen levels GO:0071453 1 0.044
macromolecule biosynthetic process GO:0009059 227 0.044
enzyme linked receptor protein signaling pathway GO:0007167 106 0.043
negative regulation of leukocyte differentiation GO:1902106 1 0.043
definitive hemopoiesis GO:0060216 18 0.043
regulation of cell communication GO:0010646 232 0.041
osteoclast differentiation GO:0030316 1 0.041
indole containing compound biosynthetic process GO:0042435 1 0.041
cell differentiation in spinal cord GO:0021515 40 0.041
regulation of protein binding GO:0043393 3 0.040
response to carbohydrate GO:0009743 3 0.040
oxoacid metabolic process GO:0043436 31 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.040
signal transduction in absence of ligand GO:0038034 1 0.040
response to biotic stimulus GO:0009607 97 0.040
lymphocyte proliferation GO:0046651 1 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
response to oxygen levels GO:0070482 25 0.038
serotonin metabolic process GO:0042428 1 0.038
negative regulation of biological process GO:0048519 304 0.038
organic substance biosynthetic process GO:1901576 289 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.037
negative regulation of apoptotic process GO:0043066 55 0.037
response to other organism GO:0051707 97 0.037
epithelial cell differentiation GO:0030855 116 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
positive regulation of cell adhesion GO:0045785 1 0.036
cellular response to starvation GO:0009267 1 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.035
negative regulation of mapk cascade GO:0043409 4 0.035
regulation of apoptotic process GO:0042981 98 0.034
regulation of response to stimulus GO:0048583 269 0.034
digestive system process GO:0022600 9 0.034
cellular response to extracellular stimulus GO:0031668 2 0.034
macrophage chemotaxis GO:0048246 3 0.033
myeloid cell homeostasis GO:0002262 56 0.033
positive regulation of epithelial cell migration GO:0010634 2 0.033
dopamine metabolic process GO:0042417 2 0.033
endocrine system development GO:0035270 65 0.033
cation transport GO:0006812 81 0.033
pancreatic a cell development GO:0003322 2 0.032
regulation of signaling GO:0023051 235 0.032
tube morphogenesis GO:0035239 349 0.032
dopamine biosynthetic process GO:0042416 2 0.032
rna metabolic process GO:0016070 219 0.032
sensory system development GO:0048880 76 0.031
cellular biosynthetic process GO:0044249 286 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
angiogenesis GO:0001525 158 0.031
nucleic acid templated transcription GO:0097659 181 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.031
indole containing compound metabolic process GO:0042430 2 0.030
endocrine process GO:0050886 2 0.030
regulation of cell activation GO:0050865 1 0.030
cellular ketone metabolic process GO:0042180 11 0.030
establishment of localization GO:0051234 244 0.029
signal transduction GO:0007165 455 0.029
positive regulation of cytoskeleton organization GO:0051495 3 0.029
cellular iron ion homeostasis GO:0006879 3 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
homeostasis of number of cells GO:0048872 62 0.028
regulation of circadian sleep wake cycle GO:0042749 1 0.028
alpha amino acid metabolic process GO:1901605 3 0.028
carboxylic acid metabolic process GO:0019752 22 0.027
response to abiotic stimulus GO:0009628 122 0.027
leukocyte differentiation GO:0002521 25 0.027
cellular response to molecule of bacterial origin GO:0071219 3 0.027
aromatic amino acid family metabolic process GO:0009072 1 0.026
optomotor response GO:0071632 1 0.026
embryonic axis specification GO:0000578 12 0.026
positive regulation of cytokine production GO:0001819 2 0.026
multicellular organismal response to stress GO:0033555 2 0.026
regulation of sodium ion transport GO:0002028 2 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.026
hormone secretion GO:0046879 2 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
regulation of binding GO:0051098 3 0.025
negative regulation of myeloid cell differentiation GO:0045638 1 0.025
embryonic digestive tract morphogenesis GO:0048557 3 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
regulation of cell death GO:0010941 103 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.025
regulation of cell shape GO:0008360 1 0.025
neuroblast proliferation GO:0007405 2 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
positive regulation of histone modification GO:0031058 1 0.024
regulation of protein complex assembly GO:0043254 3 0.024
stem cell proliferation GO:0072089 4 0.024
transport GO:0006810 220 0.023
generation of neurons GO:0048699 385 0.023
regulation of developmental process GO:0050793 247 0.023
regulation of programmed cell death GO:0043067 101 0.022
behavior GO:0007610 74 0.022
branching morphogenesis of an epithelial tube GO:0048754 15 0.022
vasculogenesis GO:0001570 41 0.022
carbohydrate homeostasis GO:0033500 1 0.022
type b pancreatic cell development GO:0003323 4 0.022
cardiac chamber formation GO:0003207 4 0.022
negative regulation of cellular process GO:0048523 283 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
appendage morphogenesis GO:0035107 56 0.022
regulation of cytokine production GO:0001817 3 0.022
eye morphogenesis GO:0048592 144 0.022
meiotic nuclear division GO:0007126 4 0.022
osteoclast development GO:0036035 1 0.022
catecholamine biosynthetic process GO:0042423 2 0.021
circadian sleep wake cycle sleep GO:0050802 1 0.021
lipid storage GO:0019915 1 0.021
lateral line development GO:0048882 66 0.021
granulocyte chemotaxis GO:0071621 11 0.021
regulation of biological quality GO:0065008 263 0.021
cellular transition metal ion homeostasis GO:0046916 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
pigmentation GO:0043473 85 0.020
granulocyte migration GO:0097530 11 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of fatty acid metabolic process GO:0019217 1 0.020
nucleic acid metabolic process GO:0090304 244 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
cellular response to reactive oxygen species GO:0034614 2 0.019
cell matrix adhesion GO:0007160 4 0.019
spinal cord development GO:0021510 46 0.019
hormone transport GO:0009914 2 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
primary amino compound metabolic process GO:1901160 1 0.019
regulation of biosynthetic process GO:0009889 250 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
leukocyte migration GO:0050900 15 0.019
gas transport GO:0015669 3 0.019
negative regulation of cell death GO:0060548 60 0.019
cellular response to external stimulus GO:0071496 2 0.018
cell proliferation GO:0008283 80 0.018
positive regulation of gliogenesis GO:0014015 2 0.018
aorta development GO:0035904 4 0.018
positive regulation of positive chemotaxis GO:0050927 4 0.018
regulation of circadian rhythm GO:0042752 4 0.018
protein heterooligomerization GO:0051291 1 0.018
apoptotic signaling pathway GO:0097190 23 0.018
negative regulation of heart contraction GO:0045822 2 0.018
myeloid leukocyte differentiation GO:0002573 15 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
maintenance of location GO:0051235 4 0.018
regulation of reproductive process GO:2000241 4 0.018
hypothalamus development GO:0021854 14 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
ion transmembrane transport GO:0034220 91 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
regulation of cellular component organization GO:0051128 86 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
macroautophagy GO:0016236 1 0.017
sequestering of metal ion GO:0051238 3 0.017
respiratory burst GO:0045730 2 0.017
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.017
positive regulation of cell activation GO:0050867 1 0.017
nitric oxide metabolic process GO:0046209 2 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
positive regulation of lipid metabolic process GO:0045834 1 0.017
positive regulation of cell matrix adhesion GO:0001954 1 0.017
positive regulation of immune system process GO:0002684 17 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
appendage development GO:0048736 80 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
organic acid catabolic process GO:0016054 3 0.016
myeloid leukocyte migration GO:0097529 12 0.016
sequestering of calcium ion GO:0051208 3 0.016
embryonic skeletal system development GO:0048706 97 0.016
enteric nervous system development GO:0048484 12 0.016
adherens junction organization GO:0034332 4 0.016
renal tubule morphogenesis GO:0061333 1 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
neutral amino acid transport GO:0015804 2 0.016
regulation of autophagy GO:0010506 3 0.015
protein metabolic process GO:0019538 183 0.015
gland development GO:0048732 143 0.015
peptide metabolic process GO:0006518 1 0.015
leukocyte chemotaxis GO:0030595 12 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
response to estrogen GO:0043627 27 0.015
stem cell fate commitment GO:0048865 1 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
epithelial cell development GO:0002064 42 0.015
olfactory bulb development GO:0021772 4 0.015
cytoskeleton organization GO:0007010 96 0.014
neutrophil migration GO:1990266 10 0.014
regulation of tissue remodeling GO:0034103 2 0.014
regulation of molecular function GO:0065009 70 0.014
gastrulation GO:0007369 208 0.014
negative regulation of blood circulation GO:1903523 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
membrane raft organization GO:0031579 1 0.014
regulation of organ growth GO:0046620 3 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
fin development GO:0033333 77 0.014
positive regulation of cell substrate adhesion GO:0010811 1 0.014
respiratory system development GO:0060541 5 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of glucose import GO:0046324 1 0.014
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.014
stem cell maintenance GO:0019827 4 0.014
neuroepithelial cell differentiation GO:0060563 26 0.014
single organism transport GO:0044765 206 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
nephron morphogenesis GO:0072028 2 0.014
programmed cell death GO:0012501 119 0.013
positive regulation of transport GO:0051050 2 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
neurotransmitter transport GO:0006836 2 0.013
response to hypoxia GO:0001666 25 0.013
nephron tubule morphogenesis GO:0072078 1 0.013
central nervous system myelin formation GO:0032289 1 0.013
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.013
primitive hemopoiesis GO:0060215 27 0.013
catechol containing compound biosynthetic process GO:0009713 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
embryonic digestive tract development GO:0048566 4 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of metabolic process GO:0019222 359 0.013
positive regulation of catabolic process GO:0009896 4 0.013
positive regulation of translation GO:0045727 1 0.013
organ formation GO:0048645 17 0.013
glucose import GO:0046323 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
positive regulation of gene expression GO:0010628 71 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.013
aorta morphogenesis GO:0035909 3 0.013
synaptic transmission glycinergic GO:0060012 1 0.013
single organism behavior GO:0044708 24 0.013
sex determination GO:0007530 1 0.013
organic hydroxy compound transport GO:0015850 14 0.013
negative regulation of cell communication GO:0010648 96 0.013
lymphoid lineage cell migration into thymus GO:0097535 4 0.013
eye development GO:0001654 277 0.013
positive regulation of macrophage chemotaxis GO:0010759 1 0.013
posterior lateral line development GO:0048916 38 0.013
muscle fiber development GO:0048747 52 0.013
regulation of neuron migration GO:2001222 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 10 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of mrna processing GO:0050684 3 0.012
meiotic cell cycle process GO:1903046 3 0.012
serotonin transport GO:0006837 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
anion transmembrane transport GO:0098656 12 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
neural crest cell development GO:0014032 62 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
adrenal gland development GO:0030325 10 0.012
positive regulation of neuron migration GO:2001224 2 0.012
regulation of localization GO:0032879 104 0.012
response to external biotic stimulus GO:0043207 97 0.012
single organism organelle organization GO:1902589 199 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
myeloid cell development GO:0061515 32 0.012
macrophage differentiation GO:0030225 7 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
venous blood vessel development GO:0060841 9 0.012
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.012
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
membrane fusion GO:0061025 2 0.012
response to organic substance GO:0010033 153 0.012
cellular cation homeostasis GO:0030003 17 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
peptide transport GO:0015833 1 0.011
heart contraction GO:0060047 71 0.011
spindle assembly GO:0051225 2 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.011
positive regulation of leukocyte migration GO:0002687 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
megakaryocyte differentiation GO:0030219 1 0.011
cation transmembrane transport GO:0098655 65 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
homeostatic process GO:0042592 142 0.011
tissue remodeling GO:0048771 4 0.011
amino acid transport GO:0006865 2 0.011
positive chemotaxis GO:0050918 5 0.011
rna biosynthetic process GO:0032774 181 0.011
negative regulation of catalytic activity GO:0043086 21 0.011
regulation of muscle contraction GO:0006937 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
spinal cord motor neuron differentiation GO:0021522 26 0.011
regulation of glucose transport GO:0010827 1 0.011
digestive system development GO:0055123 289 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of calcium ion transport GO:0051924 2 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
heterocycle metabolic process GO:0046483 290 0.010
pectoral fin development GO:0033339 50 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
ventral spinal cord development GO:0021517 35 0.010
neutrophil chemotaxis GO:0030593 10 0.010
protein acetylation GO:0006473 2 0.010
response to hydrogen peroxide GO:0042542 3 0.010
segment polarity determination GO:0007367 1 0.010
response to glucose GO:0009749 3 0.010
negative regulation of secretion by cell GO:1903531 2 0.010

fev disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033
disease of metabolism DOID:0014667 0 0.012