Danio rerio

0 known processes

tomm34

translocase of outer mitochondrial membrane 34

(Aliases: wu:fb96b08,zgc:56645)

tomm34 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 4 0.350
Human
aging GO:0007568 2 0.244
regulation of nucleoside metabolic process GO:0009118 2 0.202
purine containing compound metabolic process GO:0072521 29 0.162
regulation of macromolecule metabolic process GO:0060255 317 0.160
cellular aromatic compound metabolic process GO:0006725 295 0.159
small molecule metabolic process GO:0044281 77 0.154
atp catabolic process GO:0006200 4 0.151
negative regulation of biological process GO:0048519 304 0.142
cellular macromolecule metabolic process GO:0044260 391 0.137
cellular nitrogen compound metabolic process GO:0034641 290 0.135
response to chemical GO:0042221 320 0.134
larval development GO:0002164 2 0.132
regulation of response to stimulus GO:0048583 269 0.132
mitochondrial transport GO:0006839 2 0.131
Human
ribose phosphate metabolic process GO:0019693 27 0.130
regulation of nucleotide metabolic process GO:0006140 17 0.130
organonitrogen compound metabolic process GO:1901564 74 0.129
ribonucleotide metabolic process GO:0009259 27 0.128
single organism organelle organization GO:1902589 199 0.121
positive regulation of cellular catabolic process GO:0031331 3 0.120
biosynthetic process GO:0009058 294 0.120
regulation of multicellular organismal process GO:0051239 277 0.119
embryo development ending in birth or egg hatching GO:0009792 271 0.117
dicarboxylic acid metabolic process GO:0043648 1 0.116
nitrogen compound metabolic process GO:0006807 319 0.113
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.112
response to external stimulus GO:0009605 264 0.111
organic cyclic compound metabolic process GO:1901360 301 0.107
nucleotide metabolic process GO:0009117 28 0.106
regulation of purine nucleotide metabolic process GO:1900542 17 0.102
guanosine containing compound catabolic process GO:1901069 2 0.100
cell cycle g1 s phase transition GO:0044843 1 0.099
cell projection organization GO:0030030 284 0.098
cellular protein metabolic process GO:0044267 129 0.096
alpha amino acid metabolic process GO:1901605 3 0.096
cellular modified amino acid metabolic process GO:0006575 3 0.096
regulation of cellular metabolic process GO:0031323 320 0.091
regulation of primary metabolic process GO:0080090 311 0.088
heterocycle metabolic process GO:0046483 290 0.087
nucleobase containing compound metabolic process GO:0006139 274 0.084
negative regulation of response to stimulus GO:0048585 104 0.081
apoptotic process GO:0006915 116 0.080
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.080
regulation of developmental process GO:0050793 247 0.080
negative regulation of cellular process GO:0048523 283 0.079
positive regulation of biological process GO:0048518 253 0.078
carbohydrate derivative metabolic process GO:1901135 61 0.075
negative regulation of signal transduction GO:0009968 94 0.074
positive regulation of catabolic process GO:0009896 4 0.074
regulation of stem cell differentiation GO:2000736 4 0.073
regulation of purine nucleotide catabolic process GO:0033121 2 0.073
regulation of nucleotide catabolic process GO:0030811 2 0.072
purine nucleotide metabolic process GO:0006163 27 0.072
gtp metabolic process GO:0046039 4 0.071
establishment of localization GO:0051234 244 0.070
Human
maintenance of location GO:0051235 4 0.069
cell death GO:0008219 121 0.068
nucleoside phosphate metabolic process GO:0006753 28 0.068
signal transduction GO:0007165 455 0.067
positive regulation of metabolic process GO:0009893 108 0.066
purine nucleoside monophosphate catabolic process GO:0009128 4 0.066
brain development GO:0007420 293 0.065
regulation of signaling GO:0023051 235 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.064
guanosine containing compound metabolic process GO:1901068 4 0.063
cellular respiration GO:0045333 3 0.062
positive regulation of nucleotide catabolic process GO:0030813 1 0.059
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.059
regulation of metabolic process GO:0019222 359 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.057
negative regulation of signaling GO:0023057 96 0.057
ribonucleotide biosynthetic process GO:0009260 20 0.056
negative regulation of cell communication GO:0010648 96 0.055
protein secretion GO:0009306 1 0.054
regulation of signal transduction GO:0009966 225 0.054
taxis GO:0042330 109 0.054
death GO:0016265 121 0.053
transport GO:0006810 220 0.052
Human
single organism metabolic process GO:0044710 217 0.052
cellular localization GO:0051641 97 0.051
Human
cellular response to chemical stimulus GO:0070887 157 0.050
g1 s transition of mitotic cell cycle GO:0000082 1 0.050
nucleoside phosphate biosynthetic process GO:1901293 21 0.050
reproductive process GO:0022414 40 0.050
regulation of gene expression GO:0010468 265 0.049
chemotaxis GO:0006935 104 0.048
purine ribonucleotide metabolic process GO:0009150 27 0.048
regulation of establishment of protein localization GO:0070201 4 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.047
nucleoside monophosphate catabolic process GO:0009125 4 0.047
establishment of protein localization to organelle GO:0072594 4 0.047
Human
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.047
purine ribonucleoside metabolic process GO:0046128 10 0.047
cell migration GO:0016477 237 0.045
sulfur compound biosynthetic process GO:0044272 9 0.044
stem cell proliferation GO:0072089 4 0.042
regulation of anatomical structure size GO:0090066 33 0.042
gtp catabolic process GO:0006184 2 0.042
cell motility GO:0048870 244 0.041
gene expression GO:0010467 252 0.041
positive regulation of nucleoside metabolic process GO:0045979 1 0.040
positive regulation of transport GO:0051050 2 0.038
single fertilization GO:0007338 3 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
cellular component movement GO:0006928 335 0.037
ribonucleoside monophosphate catabolic process GO:0009158 4 0.036
aromatic compound biosynthetic process GO:0019438 217 0.036
programmed cell death GO:0012501 119 0.036
spindle assembly GO:0051225 2 0.036
protein metabolic process GO:0019538 183 0.036
phagocytosis GO:0006909 3 0.035
cellular protein localization GO:0034613 20 0.035
Human
response to topologically incorrect protein GO:0035966 2 0.035
organic substance biosynthetic process GO:1901576 289 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
regulation of cell communication GO:0010646 232 0.033
single organism nuclear import GO:1902593 3 0.032
locomotion GO:0040011 313 0.031
localization of cell GO:0051674 244 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
organic substance transport GO:0071702 58 0.031
Human
positive regulation of cellular process GO:0048522 201 0.031
head development GO:0060322 303 0.031
intracellular estrogen receptor signaling pathway GO:0030520 3 0.030
reproduction GO:0000003 40 0.030
regulation of blood vessel size GO:0050880 2 0.030
nuclear transport GO:0051169 4 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
phosphate containing compound metabolic process GO:0006796 108 0.029
spermatid development GO:0007286 2 0.029
cellular response to unfolded protein GO:0034620 2 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
positive regulation of cell cycle GO:0045787 3 0.029
regulation of phosphorus metabolic process GO:0051174 43 0.029
nuclear export GO:0051168 1 0.029
cell part morphogenesis GO:0032990 246 0.029
single organism localization GO:1902578 225 0.028
Human
growth GO:0040007 174 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
neurotransmitter secretion GO:0007269 2 0.028
regulation of gtp catabolic process GO:0033124 2 0.027
oxoacid metabolic process GO:0043436 31 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
regulation of cytoplasmic transport GO:1903649 4 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
tissue remodeling GO:0048771 4 0.026
vesicle localization GO:0051648 27 0.026
organic acid metabolic process GO:0006082 31 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
axon ensheathment in central nervous system GO:0032291 2 0.026
pronuclear migration GO:0035046 1 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
nucleobase containing small molecule metabolic process GO:0055086 32 0.025
phosphorus metabolic process GO:0006793 109 0.025
nucleic acid templated transcription GO:0097659 181 0.025
cellular component biogenesis GO:0044085 178 0.024
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.024
amino acid transport GO:0006865 2 0.024
phosphorylation GO:0016310 69 0.024
amine metabolic process GO:0009308 2 0.024
organelle fusion GO:0048284 3 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
mesenchyme development GO:0060485 127 0.024
establishment of organelle localization GO:0051656 45 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
reactive oxygen species biosynthetic process GO:1903409 1 0.024
regulation of myotube differentiation GO:0010830 2 0.023
organophosphate metabolic process GO:0019637 37 0.023
cellular amino acid biosynthetic process GO:0008652 2 0.023
protein import GO:0017038 3 0.023
organelle organization GO:0006996 227 0.023
Human
regulation of phosphate metabolic process GO:0019220 43 0.023
single organism cellular localization GO:1902580 46 0.023
Human
oxidative phosphorylation GO:0006119 1 0.023
positive regulation of gtpase activity GO:0043547 1 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
cell proliferation GO:0008283 80 0.023
nucleoside metabolic process GO:0009116 11 0.022
behavior GO:0007610 74 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
single organism transport GO:0044765 206 0.022
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
positive regulation of gtp catabolic process GO:0033126 1 0.022
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
kidney development GO:0001822 92 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
meiotic nuclear division GO:0007126 4 0.021
response to drug GO:0042493 3 0.021
regulation of tube size GO:0035150 2 0.021
striated muscle cell differentiation GO:0051146 129 0.021
skin development GO:0043588 54 0.021
protein localization GO:0008104 40 0.020
Human
cell morphogenesis GO:0000902 289 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
vasculature development GO:0001944 278 0.020
lipid storage GO:0019915 1 0.020
glycosyl compound metabolic process GO:1901657 11 0.020
neuroblast proliferation GO:0007405 2 0.020
positive regulation of molecular function GO:0044093 33 0.020
negative regulation of cell death GO:0060548 60 0.020
regulation of cell differentiation GO:0045595 142 0.020
ras protein signal transduction GO:0007265 7 0.020
cellular ketone metabolic process GO:0042180 11 0.020
establishment of vesicle localization GO:0051650 24 0.020
axonogenesis GO:0007409 152 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
regulation of neurotransmitter transport GO:0051588 1 0.019
chordate embryonic development GO:0043009 271 0.019
spermatid differentiation GO:0048515 2 0.019
regulation of programmed cell death GO:0043067 101 0.019
regulation of hydrolase activity GO:0051336 28 0.019
establishment of localization in cell GO:0051649 77 0.019
Human
cell aging GO:0007569 2 0.019
regulation of peptidase activity GO:0052547 23 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
multicellular organism growth GO:0035264 4 0.019
cellular amine metabolic process GO:0044106 2 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
regulation of behavior GO:0050795 24 0.018
synaptic vesicle transport GO:0048489 1 0.018
cilium morphogenesis GO:0060271 85 0.018
immune system process GO:0002376 241 0.018
organic substance catabolic process GO:1901575 28 0.018
developmental growth GO:0048589 166 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of apoptotic process GO:0042981 98 0.018
organelle localization GO:0051640 49 0.018
regulation of transport GO:0051049 45 0.018
microtubule based process GO:0007017 60 0.018
muscle cell differentiation GO:0042692 139 0.018
stem cell division GO:0017145 1 0.018
negative regulation of metabolic process GO:0009892 86 0.018
regulation of synapse organization GO:0050807 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
positive regulation of muscle cell differentiation GO:0051149 1 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
leukocyte proliferation GO:0070661 1 0.017
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
regulation of gtpase activity GO:0043087 2 0.017
nucleoside triphosphate biosynthetic process GO:0009142 2 0.017
protein modification process GO:0036211 100 0.017
regulation of cell death GO:0010941 103 0.017
tissue regeneration GO:0042246 74 0.017
immune system development GO:0002520 191 0.017
cellular component morphogenesis GO:0032989 336 0.017
cellular component assembly GO:0022607 170 0.017
Zebrafish
positive regulation of hydrolase activity GO:0051345 13 0.016
response to nutrient GO:0007584 3 0.016
regulation of biosynthetic process GO:0009889 250 0.016
cellular response to organic substance GO:0071310 105 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
regulation of protein metabolic process GO:0051246 56 0.016
multicellular organism reproduction GO:0032504 35 0.016
cellular amide metabolic process GO:0043603 4 0.016
response to stress GO:0006950 263 0.016
compound eye development GO:0048749 2 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
response to unfolded protein GO:0006986 2 0.016
neurotransmitter transport GO:0006836 2 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
intracellular transport GO:0046907 32 0.016
Human
cellular macromolecule localization GO:0070727 21 0.016
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
response to amino acid GO:0043200 2 0.015
regulation of cell activation GO:0050865 1 0.015
cilium assembly GO:0042384 58 0.015
cytokinetic process GO:0032506 2 0.015
rna metabolic process GO:0016070 219 0.015
synaptic vesicle localization GO:0097479 1 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
protein localization to nucleus GO:0034504 3 0.015
central nervous system development GO:0007417 387 0.015
response to wounding GO:0009611 116 0.015
cellular protein modification process GO:0006464 100 0.015
multi organism process GO:0051704 134 0.015
regulation of epithelial to mesenchymal transition GO:0010717 3 0.015
nucleotide biosynthetic process GO:0009165 21 0.015
ion transport GO:0006811 114 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
rna localization GO:0006403 4 0.014
regulation of cellular component organization GO:0051128 86 0.014
response to biotic stimulus GO:0009607 97 0.014
purine nucleoside triphosphate metabolic process GO:0009144 9 0.014
regulation of protein polymerization GO:0032271 2 0.014
generation of neurons GO:0048699 385 0.014
positive regulation of developmental process GO:0051094 50 0.014
regulation of catalytic activity GO:0050790 55 0.014
regulation of molecular function GO:0065009 70 0.014
generation of precursor metabolites and energy GO:0006091 5 0.014
regulation of cell projection assembly GO:0060491 4 0.014
hemopoiesis GO:0030097 183 0.014
muscle structure development GO:0061061 196 0.014
skeletal system development GO:0001501 181 0.014
antimicrobial humoral response GO:0019730 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.013
rna biosynthetic process GO:0032774 181 0.013
regeneration GO:0031099 91 0.013
regulation of metal ion transport GO:0010959 4 0.013
nucleoside triphosphate metabolic process GO:0009141 9 0.013
germ line stem cell division GO:0042078 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
renal system development GO:0072001 94 0.013
regulation of proteolysis GO:0030162 24 0.013
cytoskeleton organization GO:0007010 96 0.013
connective tissue development GO:0061448 99 0.013
zymogen activation GO:0031638 3 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
positive regulation of ras gtpase activity GO:0032320 1 0.013
regulation of reproductive process GO:2000241 4 0.013
fin regeneration GO:0031101 51 0.013
negative regulation of defense response GO:0031348 2 0.013
mononuclear cell proliferation GO:0032943 1 0.013
mesenchymal cell development GO:0014031 78 0.013
protein targeting to nucleus GO:0044744 3 0.013
peptide metabolic process GO:0006518 1 0.013
cellular response to external stimulus GO:0071496 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
cation transport GO:0006812 81 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
regulation of protein binding GO:0043393 3 0.013
regulation of endopeptidase activity GO:0052548 23 0.013
cartilage development GO:0051216 96 0.013
negative regulation of reproductive process GO:2000242 3 0.013
positive regulation of striated muscle cell differentiation GO:0051155 1 0.013
water homeostasis GO:0030104 4 0.013
single organism reproductive process GO:0044702 40 0.013
regulation of localization GO:0032879 104 0.013
organic cyclic compound catabolic process GO:1901361 15 0.012
cell projection assembly GO:0030031 64 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of developmental growth GO:0048638 38 0.012
b cell activation GO:0042113 2 0.012
regulation of protein transport GO:0051223 3 0.012
urogenital system development GO:0001655 97 0.012
protein import into nucleus GO:0006606 3 0.012
cell cycle process GO:0022402 53 0.012
regulation of binding GO:0051098 3 0.012
protein complex assembly GO:0006461 30 0.012
Zebrafish
axon development GO:0061564 166 0.012
toxin transport GO:1901998 2 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
purine nucleoside monophosphate metabolic process GO:0009126 5 0.012
mitochondrion morphogenesis GO:0070584 2 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
transcription dna templated GO:0006351 181 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
single organism biosynthetic process GO:0044711 71 0.012
sexual reproduction GO:0019953 36 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
cilium organization GO:0044782 71 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
coenzyme biosynthetic process GO:0009108 2 0.012
regulation of jun kinase activity GO:0043506 3 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
macromolecule localization GO:0033036 54 0.012
Human
transmembrane transport GO:0055085 120 0.012
er nucleus signaling pathway GO:0006984 2 0.012
hindbrain development GO:0030902 91 0.012
ribonucleoside metabolic process GO:0009119 11 0.012
meiotic chromosome segregation GO:0045132 3 0.012
nuclear migration GO:0007097 3 0.012
chromosome organization involved in meiosis GO:0070192 1 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
amide biosynthetic process GO:0043604 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of cytokine production GO:0001817 3 0.011
somatic muscle development GO:0007525 4 0.011
neuron development GO:0048666 262 0.011
ribonucleoside biosynthetic process GO:0042455 2 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
oocyte maturation GO:0001556 4 0.011
apical junction assembly GO:0043297 1 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
neuron projection morphogenesis GO:0048812 161 0.011
fertilization GO:0009566 3 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
wound healing GO:0042060 90 0.011
single organism intracellular transport GO:1902582 25 0.011
Human
gland development GO:0048732 143 0.011
epithelial cell differentiation GO:0030855 116 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of biological quality GO:0065008 263 0.011
neuron differentiation GO:0030182 353 0.011
spermatogenesis GO:0007283 7 0.011
adult behavior GO:0030534 2 0.011
neuron projection guidance GO:0097485 86 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
cell growth GO:0016049 57 0.010
renal tubule morphogenesis GO:0061333 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
regulation of rna metabolic process GO:0051252 224 0.010
cellular response to light stimulus GO:0071482 4 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
cell projection morphogenesis GO:0048858 244 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
single organism membrane fusion GO:0044801 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
cell cycle GO:0007049 93 0.010
sequestering of calcium ion GO:0051208 3 0.010
hormone secretion GO:0046879 2 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
intracellular signal transduction GO:0035556 85 0.010

tomm34 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.303
disease of anatomical entity DOID:7 0 0.303
eye and adnexa disease DOID:1492 0 0.303
nervous system disease DOID:863 0 0.303
eye disease DOID:5614 0 0.303