Danio rerio

186 known processes

ruvbl2

RuvB-like 2 (E. coli)

(Aliases: zreptin,reptin,wu:fi25f01)

ruvbl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.985
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.644
Worm
cellular component movement GO:0006928 335 0.599
rna metabolic process GO:0016070 219 0.560
organelle organization GO:0006996 227 0.547
locomotion GO:0040011 313 0.513
Worm
regulation of multicellular organismal process GO:0051239 277 0.487
cellular component biogenesis GO:0044085 178 0.386
reproduction GO:0000003 40 0.363
Worm
organelle assembly GO:0070925 110 0.329
nitrogen compound metabolic process GO:0006807 319 0.326
single organism metabolic process GO:0044710 217 0.323
regulation of developmental process GO:0050793 247 0.291
establishment of localization GO:0051234 244 0.278
Human Worm
single organism organelle organization GO:1902589 199 0.267
gene expression GO:0010467 252 0.250
ribosomal small subunit biogenesis GO:0042274 2 0.247
pore complex assembly GO:0046931 2 0.227
growth GO:0040007 174 0.220
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.217
maturation of ssu rrna GO:0030490 1 0.201
chordate embryonic development GO:0043009 271 0.192
spindle assembly involved in mitosis GO:0090307 1 0.186
regulation of protein binding GO:0043393 3 0.184
Human
tube morphogenesis GO:0035239 349 0.183
nucleobase containing compound metabolic process GO:0006139 274 0.176
regulation of nitrogen compound metabolic process GO:0051171 251 0.173
meiotic chromosome segregation GO:0045132 3 0.172
macromolecular complex subunit organization GO:0043933 74 0.169
cellular component assembly GO:0022607 170 0.160
regulation of nucleocytoplasmic transport GO:0046822 2 0.159
single organism reproductive process GO:0044702 40 0.147
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.145
regulation of primary metabolic process GO:0080090 311 0.139
cellular nitrogen compound metabolic process GO:0034641 290 0.131
negative regulation of ras protein signal transduction GO:0046580 1 0.131
generation of neurons GO:0048699 385 0.124
nuclear pore complex assembly GO:0051292 2 0.122
microtubule based process GO:0007017 60 0.121
positive regulation of biological process GO:0048518 253 0.121
Human
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.119
response to external stimulus GO:0009605 264 0.118
organic cyclic compound metabolic process GO:1901360 301 0.116
regulation of response to stimulus GO:0048583 269 0.116
macromolecule biosynthetic process GO:0009059 227 0.114
cell projection organization GO:0030030 284 0.113
regulation of establishment of protein localization GO:0070201 4 0.112
multicellular organism growth GO:0035264 4 0.110
positive regulation of cellular process GO:0048522 201 0.109
Human
transport GO:0006810 220 0.105
Worm
eye development GO:0001654 277 0.101
meiotic nuclear division GO:0007126 4 0.101
sensory organ development GO:0007423 393 0.100
nuclear transport GO:0051169 4 0.099
muscle structure development GO:0061061 196 0.098
organic substance biosynthetic process GO:1901576 289 0.091
fertilization GO:0009566 3 0.089
regulation of gene expression GO:0010468 265 0.088
establishment of localization in cell GO:0051649 77 0.084
regulation of protein transport GO:0051223 3 0.082
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.081
response to organic substance GO:0010033 153 0.080
Human
small molecule metabolic process GO:0044281 77 0.080
signal transduction GO:0007165 455 0.079
rna localization GO:0006403 4 0.079
cellular component morphogenesis GO:0032989 336 0.076
cellular nitrogen compound biosynthetic process GO:0044271 218 0.076
regulation of binding GO:0051098 3 0.076
Human
cellular macromolecule metabolic process GO:0044260 391 0.076
regulation of metabolic process GO:0019222 359 0.075
proteasomal protein catabolic process GO:0010498 2 0.070
organic substance transport GO:0071702 58 0.069
cytoskeleton organization GO:0007010 96 0.069
mitotic cell cycle process GO:1903047 48 0.069
single fertilization GO:0007338 3 0.068
regulation of multicellular organism growth GO:0040014 4 0.067
g protein coupled receptor signaling pathway GO:0007186 74 0.067
multi organism process GO:0051704 134 0.064
nucleic acid metabolic process GO:0090304 244 0.064
cellular macromolecule biosynthetic process GO:0034645 224 0.063
macromolecular complex assembly GO:0065003 35 0.062
regulation of intracellular protein transport GO:0033157 3 0.062
aromatic compound biosynthetic process GO:0019438 217 0.062
protein import GO:0017038 3 0.061
single organism localization GO:1902578 225 0.060
organonitrogen compound metabolic process GO:1901564 74 0.060
neuron differentiation GO:0030182 353 0.060
programmed cell death GO:0012501 119 0.059
rrna processing GO:0006364 7 0.059
protein complex subunit organization GO:0071822 46 0.059
translational initiation GO:0006413 3 0.059
heterocycle biosynthetic process GO:0018130 215 0.059
regulation of cytoplasmic transport GO:1903649 4 0.059
regulation of mrna processing GO:0050684 3 0.058
oxoacid metabolic process GO:0043436 31 0.057
organic substance catabolic process GO:1901575 28 0.055
cell surface receptor signaling pathway GO:0007166 325 0.055
heterocycle metabolic process GO:0046483 290 0.054
nuclear import GO:0051170 3 0.054
biosynthetic process GO:0009058 294 0.054
eye morphogenesis GO:0048592 144 0.054
regulation of protein localization to nucleus GO:1900180 2 0.053
establishment of protein localization to organelle GO:0072594 4 0.052
Human
regulation of meiotic cell cycle GO:0051445 1 0.052
protein targeting to nucleus GO:0044744 3 0.052
cell cycle GO:0007049 93 0.052
nucleocytoplasmic transport GO:0006913 4 0.051
regulation of biological quality GO:0065008 263 0.051
single organism transport GO:0044765 206 0.049
embryonic digestive tract morphogenesis GO:0048557 3 0.048
axonogenesis GO:0007409 152 0.048
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.047
homeostatic process GO:0042592 142 0.047
regulation of signaling GO:0023051 235 0.046
intracellular transport GO:0046907 32 0.046
death GO:0016265 121 0.046
spindle assembly GO:0051225 2 0.046
protein import into nucleus GO:0006606 3 0.046
sex differentiation GO:0007548 5 0.045
Worm
cell migration GO:0016477 237 0.045
regulation of cell death GO:0010941 103 0.045
neuron projection morphogenesis GO:0048812 161 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.044
protein localization to nucleus GO:0034504 3 0.044
digestive tract morphogenesis GO:0048546 231 0.044
nucleus organization GO:0006997 7 0.044
modification dependent macromolecule catabolic process GO:0043632 3 0.043
response to stress GO:0006950 263 0.043
nuclear pore organization GO:0006999 2 0.042
digestive system development GO:0055123 289 0.042
central nervous system development GO:0007417 387 0.041
body morphogenesis GO:0010171 16 0.041
regulation of transcription dna templated GO:0006355 213 0.041
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.041
positive regulation of catabolic process GO:0009896 4 0.040
amine metabolic process GO:0009308 2 0.040
cell motility GO:0048870 244 0.040
regulation of protein targeting GO:1903533 2 0.039
rna export from nucleus GO:0006405 1 0.039
pancreas development GO:0031016 84 0.039
regulation of metal ion transport GO:0010959 4 0.038
nuclear export GO:0051168 1 0.038
signal transduction downstream of smoothened GO:0007227 1 0.037
ncrna metabolic process GO:0034660 12 0.037
maintenance of location GO:0051235 4 0.037
phosphate containing compound metabolic process GO:0006796 108 0.036
protein complex assembly GO:0006461 30 0.036
membrane repolarization GO:0086009 2 0.036
cell projection morphogenesis GO:0048858 244 0.035
cellular amine metabolic process GO:0044106 2 0.035
rna modification GO:0009451 2 0.035
positive regulation of nucleoside metabolic process GO:0045979 1 0.035
viral process GO:0016032 1 0.035
rna transport GO:0050658 2 0.034
reproductive structure development GO:0048608 5 0.034
Worm
transcription dna templated GO:0006351 181 0.034
neuron development GO:0048666 262 0.034
cellular localization GO:0051641 97 0.034
Human
ion transmembrane transport GO:0034220 91 0.033
localization of cell GO:0051674 244 0.033
regeneration GO:0031099 91 0.033
axon development GO:0061564 166 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
development of primary sexual characteristics GO:0045137 5 0.033
Worm
nucleic acid transport GO:0050657 2 0.032
developmental programmed cell death GO:0010623 4 0.032
pronuclear migration GO:0035046 1 0.032
cell part morphogenesis GO:0032990 246 0.032
immune system process GO:0002376 241 0.031
mitotic spindle organization GO:0007052 5 0.031
regulation of apoptotic process GO:0042981 98 0.031
nucleoside monophosphate catabolic process GO:0009125 4 0.031
developmental process involved in reproduction GO:0003006 27 0.030
Worm
reproductive process GO:0022414 40 0.030
Worm
striated muscle cell differentiation GO:0051146 129 0.030
regulation of localization GO:0032879 104 0.029
negative regulation of gene expression GO:0010629 65 0.029
positive regulation of cytokine production GO:0001819 2 0.029
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.029
muscle cell differentiation GO:0042692 139 0.029
macromolecule catabolic process GO:0009057 15 0.029
interspecies interaction between organisms GO:0044419 4 0.029
activation of mapkkk activity GO:0000185 1 0.029
aging GO:0007568 2 0.029
apoptotic process GO:0006915 116 0.028
regulation of protein import into nucleus GO:0042306 2 0.028
regulation of cell differentiation GO:0045595 142 0.028
cell proliferation GO:0008283 80 0.027
embryonic digestive tract development GO:0048566 4 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
positive regulation of cellular metabolic process GO:0031325 94 0.027
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
retina development in camera type eye GO:0060041 146 0.026
centrosome organization GO:0051297 1 0.026
cilium assembly GO:0042384 58 0.026
positive regulation of gene expression GO:0010628 71 0.026
Human
vasculature development GO:0001944 278 0.026
regulation of stem cell proliferation GO:0072091 2 0.026
positive regulation of cell cycle GO:0045787 3 0.025
positive regulation of transport GO:0051050 2 0.025
cellular protein catabolic process GO:0044257 4 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
cellular protein modification process GO:0006464 100 0.024
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
negative regulation of metabolic process GO:0009892 86 0.024
chromatin modification GO:0016568 21 0.024
Human
rna biosynthetic process GO:0032774 181 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
negative regulation of protein transport GO:0051224 3 0.024
cellular catabolic process GO:0044248 27 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
regulation of cellular metabolic process GO:0031323 320 0.022
carbohydrate derivative metabolic process GO:1901135 61 0.022
myofibril assembly GO:0030239 48 0.022
myeloid cell homeostasis GO:0002262 56 0.022
cellular component disassembly GO:0022411 1 0.022
cell death GO:0008219 121 0.022
single organism nuclear import GO:1902593 3 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
regulation of intracellular signal transduction GO:1902531 57 0.022
mitotic nuclear division GO:0007067 18 0.022
cilium organization GO:0044782 71 0.022
cytokinesis GO:0000910 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
single organism cellular localization GO:1902580 46 0.021
peptidyl serine modification GO:0018209 2 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
gtp metabolic process GO:0046039 4 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
atp catabolic process GO:0006200 4 0.021
cellular ketone metabolic process GO:0042180 11 0.021
homologous chromosome segregation GO:0045143 1 0.021
post embryonic development GO:0009791 7 0.020
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
regulation of programmed cell death GO:0043067 101 0.020
lateral line system development GO:0048925 76 0.020
regulation of cell communication GO:0010646 232 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
ncrna processing GO:0034470 8 0.020
intracellular signal transduction GO:0035556 85 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
chemotaxis GO:0006935 104 0.020
negative regulation of cell death GO:0060548 60 0.020
reproductive system development GO:0061458 5 0.019
Worm
ribonucleotide metabolic process GO:0009259 27 0.019
muscle cell development GO:0055001 115 0.019
proximal distal pattern formation GO:0009954 1 0.019
energy reserve metabolic process GO:0006112 2 0.019
protein dephosphorylation GO:0006470 3 0.019
cellular protein metabolic process GO:0044267 129 0.019
Human
gene silencing GO:0016458 4 0.019
Worm
regulation of growth rate GO:0040009 1 0.019
skeletal system development GO:0001501 181 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of cellular component organization GO:0051128 86 0.018
Human
positive regulation of embryonic development GO:0040019 3 0.018
actomyosin structure organization GO:0031032 53 0.018
circulatory system process GO:0003013 87 0.018
oligodendrocyte differentiation GO:0048709 23 0.018
regulation of protein complex disassembly GO:0043244 1 0.018
nucleobase containing compound transport GO:0015931 2 0.018
eye photoreceptor cell development GO:0042462 30 0.018
meiotic cell cycle process GO:1903046 3 0.018
ion transport GO:0006811 114 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
establishment of rna localization GO:0051236 3 0.017
nuclear migration GO:0007097 3 0.017
macromolecule localization GO:0033036 54 0.017
Human
establishment of nucleus localization GO:0040023 7 0.017
taxis GO:0042330 109 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cation transmembrane transport GO:0098655 65 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
developmental growth GO:0048589 166 0.017
response to endogenous stimulus GO:0009719 83 0.017
Human
cilium morphogenesis GO:0060271 85 0.017
cellular protein complex assembly GO:0043623 19 0.017
response to chemical GO:0042221 320 0.016
Human
astrocyte differentiation GO:0048708 1 0.016
microtubule cytoskeleton organization GO:0000226 33 0.016
cellular biosynthetic process GO:0044249 286 0.016
nucleic acid templated transcription GO:0097659 181 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
regulation of organelle assembly GO:1902115 4 0.016
mitotic g2 m transition checkpoint GO:0044818 3 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
regulation of transporter activity GO:0032409 2 0.016
negative regulation of biological process GO:0048519 304 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
rna processing GO:0006396 25 0.015
membrane organization GO:0061024 21 0.015
organic acid metabolic process GO:0006082 31 0.015
positive regulation of ras protein signal transduction GO:0046579 1 0.015
membrane hyperpolarization GO:0060081 1 0.015
phosphorus metabolic process GO:0006793 109 0.014
primary neural tube formation GO:0014020 1 0.014
extracellular matrix constituent secretion GO:0070278 3 0.014
cell cycle process GO:0022402 53 0.014
regulation of neuron projection development GO:0010975 40 0.014
regulation of glial cell differentiation GO:0045685 4 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
Human
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
protein metabolic process GO:0019538 183 0.014
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
heart morphogenesis GO:0003007 156 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
cellular response to external stimulus GO:0071496 2 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
single organism biosynthetic process GO:0044711 71 0.013
centrosome duplication GO:0051298 1 0.013
specification of axis polarity GO:0065001 4 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of developmental growth GO:0048638 38 0.013
spindle assembly involved in meiosis GO:0090306 1 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
Human
mitotic cytokinesis GO:0000281 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
spindle organization GO:0007051 5 0.013
peptide metabolic process GO:0006518 1 0.013
regulation of cytokine production GO:0001817 3 0.013
heart development GO:0007507 313 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
Human
rrna metabolic process GO:0016072 8 0.012
chromatin organization GO:0006325 22 0.012
Human
positive regulation of gliogenesis GO:0014015 2 0.012
hemopoiesis GO:0030097 183 0.012
multi organism cellular process GO:0044764 2 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
meiotic spindle organization GO:0000212 1 0.012
mrna transport GO:0051028 2 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
protein modification process GO:0036211 100 0.012
Human
cation transport GO:0006812 81 0.012
regulation of reproductive process GO:2000241 4 0.012
sensory perception GO:0007600 39 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
cellular amide metabolic process GO:0043603 4 0.011
regulation of cell projection organization GO:0031344 44 0.011
regulation of receptor activity GO:0010469 2 0.011
ras protein signal transduction GO:0007265 7 0.011
erythrocyte differentiation GO:0030218 54 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
digestive tract development GO:0048565 265 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
positive regulation of phosphate metabolic process GO:0045937 21 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
cellular response to oxygen containing compound GO:1901701 20 0.011
Human
positive regulation of developmental process GO:0051094 50 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
aorta development GO:0035904 4 0.011
regulation of neurogenesis GO:0050767 87 0.011
negative regulation of cellular process GO:0048523 283 0.011
cytoplasmic transport GO:0016482 11 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
protein acetylation GO:0006473 2 0.011
Human
intracellular mrna localization GO:0008298 1 0.011
regulation of organ growth GO:0046620 3 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
cellular response to organic substance GO:0071310 105 0.011
Human
positive regulation of metabolic process GO:0009893 108 0.011
Human
positive regulation of gtpase activity GO:0043547 1 0.011
phagocytosis GO:0006909 3 0.011
neuron projection development GO:0031175 180 0.011
cell morphogenesis GO:0000902 289 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
Human
cilium movement GO:0003341 26 0.011
purine nucleotide metabolic process GO:0006163 27 0.011
smoothened signaling pathway GO:0007224 30 0.011
cellular response to nutrient levels GO:0031669 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
Human
behavior GO:0007610 74 0.010
regulation of biosynthetic process GO:0009889 250 0.010
rna 3 end processing GO:0031123 2 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
meiosis i GO:0007127 1 0.010
neurological system process GO:0050877 62 0.010
regulation of organelle organization GO:0033043 29 0.010
Human
cellular response to endogenous stimulus GO:0071495 68 0.010
Human
tissue regeneration GO:0042246 74 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010

ruvbl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
colorectal cancer DOID:9256 0 0.011