Danio rerio

0 known processes

h1fx

H1 histone family, member X

(Aliases: wu:fb12d01,cb1061,wu:fb63d02)

h1fx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic chromosome segregation GO:0045132 3 0.334
Worm
larval development GO:0002164 2 0.247
Worm
cellular macromolecule metabolic process GO:0044260 391 0.234
positive regulation of cellular process GO:0048522 201 0.218
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.207
cellular macromolecule biosynthetic process GO:0034645 224 0.207
meiotic cell cycle process GO:1903046 3 0.162
Worm
nucleic acid metabolic process GO:0090304 244 0.156
negative regulation of cell cycle GO:0045786 14 0.150
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.136
organic cyclic compound metabolic process GO:1901360 301 0.135
cellular nitrogen compound biosynthetic process GO:0044271 218 0.118
nitrogen compound metabolic process GO:0006807 319 0.107
death GO:0016265 121 0.105
Worm
organelle organization GO:0006996 227 0.103
Worm
aromatic compound biosynthetic process GO:0019438 217 0.091
heterocycle metabolic process GO:0046483 290 0.090
regulation of cellular metabolic process GO:0031323 320 0.087
positive regulation of biological process GO:0048518 253 0.077
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.072
locomotion GO:0040011 313 0.069
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.068
Worm
single organism organelle organization GO:1902589 199 0.066
regulation of primary metabolic process GO:0080090 311 0.060
rna metabolic process GO:0016070 219 0.059
negative regulation of mitotic cell cycle GO:0045930 11 0.059
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.058
germ cell development GO:0007281 22 0.057
Worm
regulation of multicellular organismal process GO:0051239 277 0.056
negative regulation of response to stimulus GO:0048585 104 0.055
macromolecule biosynthetic process GO:0009059 227 0.053
aging GO:0007568 2 0.052
cellular biosynthetic process GO:0044249 286 0.050
hormone transport GO:0009914 2 0.046
negative regulation of macromolecule metabolic process GO:0010605 76 0.046
nuclear transport GO:0051169 4 0.044
regulation of multicellular organism growth GO:0040014 4 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.043
protein import into nucleus GO:0006606 3 0.043
protein acetylation GO:0006473 2 0.042
regulation of signal transduction GO:0009966 225 0.042
protein localization to nucleus GO:0034504 3 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
single organism reproductive process GO:0044702 40 0.041
Worm
multicellular organism growth GO:0035264 4 0.040
transport GO:0006810 220 0.039
homeostatic process GO:0042592 142 0.038
growth GO:0040007 174 0.037
regulation of mitotic cell cycle GO:0007346 25 0.037
Worm
cellular component assembly GO:0022607 170 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
biosynthetic process GO:0009058 294 0.035
single organism nuclear import GO:1902593 3 0.035
sexual reproduction GO:0019953 36 0.035
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.034
protein metabolic process GO:0019538 183 0.034
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.034
Worm
stem cell proliferation GO:0072089 4 0.033
proepicardium development GO:0003342 4 0.033
response to stress GO:0006950 263 0.033
multi organism process GO:0051704 134 0.033
Worm
phagocytosis GO:0006909 3 0.033
regulation of gene expression GO:0010468 265 0.032
negative regulation of cellular process GO:0048523 283 0.032
Worm
internal peptidyl lysine acetylation GO:0018393 2 0.032
regulation of stem cell differentiation GO:2000736 4 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.031
multicellular organismal metabolic process GO:0044236 2 0.031
cellular protein metabolic process GO:0044267 129 0.030
positive regulation of transport GO:0051050 2 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
positive regulation of protein complex assembly GO:0031334 2 0.030
response to glucose GO:0009749 3 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
regulation of transcription dna templated GO:0006355 213 0.029
regulation of developmental process GO:0050793 247 0.029
cell cycle GO:0007049 93 0.029
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
single organism metabolic process GO:0044710 217 0.028
lipid storage GO:0019915 1 0.028
maintenance of location GO:0051235 4 0.028
gene expression GO:0010467 252 0.027
signal transduction GO:0007165 455 0.027
regulation of rna metabolic process GO:0051252 224 0.027
transcription dna templated GO:0006351 181 0.027
nucleocytoplasmic transport GO:0006913 4 0.026
gtp metabolic process GO:0046039 4 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
carboxylic acid metabolic process GO:0019752 22 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.025
cell cycle g1 s phase transition GO:0044843 1 0.025
regulation of metabolic process GO:0019222 359 0.025
organic acid metabolic process GO:0006082 31 0.025
small molecule metabolic process GO:0044281 77 0.025
negative regulation of signaling GO:0023057 96 0.025
somatic muscle development GO:0007525 4 0.025
phosphorus metabolic process GO:0006793 109 0.025
regulation of cell communication GO:0010646 232 0.024
protein acylation GO:0043543 3 0.024
nuclear import GO:0051170 3 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
cell cycle arrest GO:0007050 1 0.024
regulation of reproductive process GO:2000241 4 0.023
regulation of binding GO:0051098 3 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of biological quality GO:0065008 263 0.023
endosomal transport GO:0016197 2 0.022
somatic stem cell maintenance GO:0035019 1 0.022
positive regulation of cell cycle GO:0045787 3 0.022
Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
multi organism reproductive process GO:0044703 36 0.022
Worm
positive regulation of secretion GO:0051047 1 0.022
response to hydrogen peroxide GO:0042542 3 0.022
rna biosynthetic process GO:0032774 181 0.022
organelle fusion GO:0048284 3 0.022
chromosome segregation GO:0007059 12 0.021
Worm
regulation of response to nutrient levels GO:0032107 1 0.021
regulation of response to stimulus GO:0048583 269 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
amine metabolic process GO:0009308 2 0.021
response to chemical GO:0042221 320 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
blood vessel development GO:0001568 246 0.021
macromolecule modification GO:0043412 111 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
membrane fusion GO:0061025 2 0.021
regulation of skeletal muscle fiber development GO:0048742 2 0.021
response to monosaccharide GO:0034284 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
reproductive process GO:0022414 40 0.021
Worm
cellular response to starvation GO:0009267 1 0.020
protein dephosphorylation GO:0006470 3 0.020
positive regulation of metabolic process GO:0009893 108 0.020
activation of mapk activity GO:0000187 3 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
nucleic acid templated transcription GO:0097659 181 0.020
cellular response to nutrient levels GO:0031669 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
compound eye development GO:0048749 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
protein import GO:0017038 3 0.019
response to hexose GO:0009746 3 0.019
cellular component disassembly GO:0022411 1 0.019
programmed cell death GO:0012501 119 0.019
Worm
regulation of hormone secretion GO:0046883 2 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
regulation of autophagy GO:0010506 3 0.019
peptidyl lysine acetylation GO:0018394 2 0.018
protein targeting to vacuole GO:0006623 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
septum transversum development GO:0003343 4 0.018
protein polymerization GO:0051258 4 0.018
organic substance biosynthetic process GO:1901576 289 0.017
cell death GO:0008219 121 0.017
Worm
positive regulation of catabolic process GO:0009896 4 0.017
organelle fission GO:0048285 23 0.017
Worm
response to organic substance GO:0010033 153 0.017
cellular ketone metabolic process GO:0042180 11 0.017
regulation of muscle contraction GO:0006937 3 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of signaling GO:0023051 235 0.017
regulation of protein metabolic process GO:0051246 56 0.017
circulatory system process GO:0003013 87 0.016
response to carbohydrate GO:0009743 3 0.016
ribosome assembly GO:0042255 1 0.016
stem cell maintenance GO:0019827 4 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
single organism membrane fusion GO:0044801 2 0.016
positive regulation of cytokine production GO:0001819 2 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
immune system process GO:0002376 241 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.015
b cell differentiation GO:0030183 1 0.015
positive regulation of muscle cell differentiation GO:0051149 1 0.015
regulation of dna recombination GO:0000018 2 0.015
intra s dna damage checkpoint GO:0031573 1 0.015
negative regulation of metabolic process GO:0009892 86 0.015
negative regulation of biological process GO:0048519 304 0.015
Worm
inositol lipid mediated signaling GO:0048017 2 0.015
response to vitamin GO:0033273 3 0.015
membrane invagination GO:0010324 1 0.015
gtp catabolic process GO:0006184 2 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
b cell activation GO:0042113 2 0.015
heart development GO:0007507 313 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
regulation of multicellular organismal metabolic process GO:0044246 2 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
Worm
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.015
embryonic organ development GO:0048568 381 0.015
photoreceptor cell fate commitment GO:0046552 1 0.015
organonitrogen compound metabolic process GO:1901564 74 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
hormone secretion GO:0046879 2 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
Worm
regulation of blood pressure GO:0008217 1 0.014
cell proliferation GO:0008283 80 0.014
positive regulation of translation GO:0045727 1 0.014
regulation of cell death GO:0010941 103 0.014
regulation of cytokine production GO:0001817 3 0.014
phagosome maturation GO:0090382 1 0.014
positive regulation of cell killing GO:0031343 2 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of programmed cell death GO:0043067 101 0.014
lymphocyte proliferation GO:0046651 1 0.014
transmission of nerve impulse GO:0019226 19 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.013
intracellular signal transduction GO:0035556 85 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of protein transport GO:0051223 3 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
behavior GO:0007610 74 0.013
Worm
single organism localization GO:1902578 225 0.013
regulation of myotube differentiation GO:0010830 2 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
digestive tract development GO:0048565 265 0.013
pancreas development GO:0031016 84 0.013
cellular lipid catabolic process GO:0044242 3 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
regulation of organelle assembly GO:1902115 4 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of growth GO:0040008 42 0.013
adipose tissue development GO:0060612 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
vasculature development GO:0001944 278 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
lipid homeostasis GO:0055088 3 0.013
regulation of apoptotic process GO:0042981 98 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
regulation of oocyte development GO:0060281 3 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
protein modification process GO:0036211 100 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of cell activation GO:0050865 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
proximal distal pattern formation GO:0009954 1 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
glucose homeostasis GO:0042593 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
developmental growth GO:0048589 166 0.012
negative regulation of signal transduction GO:0009968 94 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
epithelial cell differentiation GO:0030855 116 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
cellular response to radiation GO:0071478 4 0.012
cellular response to external stimulus GO:0071496 2 0.012
response to corticosteroid GO:0031960 1 0.012
peptide transport GO:0015833 1 0.012
female gonad development GO:0008585 4 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
cellular response to stress GO:0033554 62 0.012
muscle structure development GO:0061061 196 0.012
olfactory bulb development GO:0021772 4 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
positive regulation of immune effector process GO:0002699 3 0.012
cellular component biogenesis GO:0044085 178 0.012
nucleoside phosphate biosynthetic process GO:1901293 21 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
mitochondrion organization GO:0007005 4 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
immune system development GO:0002520 191 0.012
negative regulation of cell communication GO:0010648 96 0.012
positive regulation of neuron death GO:1901216 1 0.012
negative regulation of chemotaxis GO:0050922 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
nuclear export GO:0051168 1 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cellular component morphogenesis GO:0032989 336 0.011
muscle organ development GO:0007517 101 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
mitotic cell cycle process GO:1903047 48 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
dna metabolic process GO:0006259 27 0.011
vacuolar transport GO:0007034 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
calcium mediated signaling GO:0019722 2 0.011
female sex differentiation GO:0046660 4 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
olfactory lobe development GO:0021988 4 0.011
negative regulation of gene expression GO:0010629 65 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
double strand break repair GO:0006302 3 0.011
regulation of dendrite development GO:0050773 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
homeostasis of number of cells within a tissue GO:0048873 4 0.011
microtubule organizing center organization GO:0031023 1 0.010
striated muscle tissue development GO:0014706 110 0.010
dna templated transcription elongation GO:0006354 3 0.010
blood vessel morphogenesis GO:0048514 216 0.010
actin filament polymerization GO:0030041 2 0.010
response to glucocorticoid GO:0051384 1 0.010
establishment of localization GO:0051234 244 0.010
macromolecular complex disassembly GO:0032984 1 0.010
cell killing GO:0001906 2 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
phagocytosis engulfment GO:0006911 1 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
digestive system development GO:0055123 289 0.010
muscle fiber development GO:0048747 52 0.010
organophosphate biosynthetic process GO:0090407 23 0.010
regulation of biosynthetic process GO:0009889 250 0.010
developmental process involved in reproduction GO:0003006 27 0.010
Worm
mitotic dna integrity checkpoint GO:0044774 4 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
bone remodeling GO:0046849 2 0.010
regulation of metal ion transport GO:0010959 4 0.010
cytokinesis GO:0000910 3 0.010
fatty acid transport GO:0015908 1 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
endosome to lysosome transport GO:0008333 1 0.010

h1fx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.026
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
neuropathy DOID:870 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011