Danio rerio

0 known processes

gpx1a

glutathione peroxidase 1a

(Aliases: gpx1,cb690,zgc:103683,zgc:92737)

gpx1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular modified amino acid metabolic process GO:0006575 3 0.568
biosynthetic process GO:0009058 294 0.134
cellular biosynthetic process GO:0044249 286 0.128
regulation of reactive oxygen species metabolic process GO:2000377 2 0.121
cellular nitrogen compound biosynthetic process GO:0044271 218 0.118
negative regulation of biological process GO:0048519 304 0.117
regulation of gene expression GO:0010468 265 0.114
response to stress GO:0006950 263 0.105
liver development GO:0001889 96 0.095
hepaticobiliary system development GO:0061008 98 0.086
regulation of rna biosynthetic process GO:2001141 213 0.077
organic acid metabolic process GO:0006082 31 0.073
organic substance biosynthetic process GO:1901576 289 0.073
neuron differentiation GO:0030182 353 0.070
larval development GO:0002164 2 0.069
gene expression GO:0010467 252 0.068
regulation of nucleic acid templated transcription GO:1903506 213 0.064
oxoacid metabolic process GO:0043436 31 0.064
aromatic compound biosynthetic process GO:0019438 217 0.063
heterocycle biosynthetic process GO:0018130 215 0.062
maintenance of location GO:0051235 4 0.062
cellular amino acid metabolic process GO:0006520 7 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.061
transcription dna templated GO:0006351 181 0.059
extrinsic apoptotic signaling pathway GO:0097191 3 0.058
negative regulation of cell death GO:0060548 60 0.055
regulation of biosynthetic process GO:0009889 250 0.054
embryonic organ development GO:0048568 381 0.054
positive regulation of biological process GO:0048518 253 0.054
regulation of nitrogen compound metabolic process GO:0051171 251 0.053
inner ear development GO:0048839 126 0.052
macromolecule biosynthetic process GO:0009059 227 0.052
reactive oxygen species biosynthetic process GO:1903409 1 0.049
response to oxygen containing compound GO:1901700 55 0.049
lipid storage GO:0019915 1 0.048
cellular macromolecule biosynthetic process GO:0034645 224 0.048
regulation of primary metabolic process GO:0080090 311 0.046
reactive oxygen species metabolic process GO:0072593 6 0.045
negative regulation of gene expression GO:0010629 65 0.045
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
erythrocyte homeostasis GO:0034101 55 0.043
cellular response to chemical stimulus GO:0070887 157 0.043
regulation of transcription dna templated GO:0006355 213 0.043
nitrogen compound metabolic process GO:0006807 319 0.042
regulation of apoptotic process GO:0042981 98 0.042
locomotion GO:0040011 313 0.041
cell morphogenesis involved in differentiation GO:0000904 195 0.041
small molecule metabolic process GO:0044281 77 0.041
organic cyclic compound metabolic process GO:1901360 301 0.040
single organism metabolic process GO:0044710 217 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
nucleic acid templated transcription GO:0097659 181 0.038
rna biosynthetic process GO:0032774 181 0.038
nucleobase containing compound biosynthetic process GO:0034654 205 0.037
heterocycle metabolic process GO:0046483 290 0.037
regulation of binding GO:0051098 3 0.036
response to nutrient GO:0007584 3 0.035
homeostatic process GO:0042592 142 0.035
response to drug GO:0042493 3 0.035
regulation of biological quality GO:0065008 263 0.035
cell proliferation GO:0008283 80 0.035
growth GO:0040007 174 0.035
regulation of metabolic process GO:0019222 359 0.035
regulation of cellular biosynthetic process GO:0031326 245 0.034
response to chemical GO:0042221 320 0.034
cellular amine metabolic process GO:0044106 2 0.034
gland development GO:0048732 143 0.033
myeloid cell homeostasis GO:0002262 56 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
single organism biosynthetic process GO:0044711 71 0.033
immune system process GO:0002376 241 0.032
reactive nitrogen species metabolic process GO:2001057 0 0.032
aging GO:0007568 2 0.031
response to glucocorticoid GO:0051384 1 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
nucleocytoplasmic transport GO:0006913 4 0.030
response to wounding GO:0009611 116 0.030
sensory organ development GO:0007423 393 0.030
ion transmembrane transport GO:0034220 91 0.029
programmed cell death GO:0012501 119 0.029
hydrogen peroxide metabolic process GO:0042743 2 0.029
transcription from rna polymerase ii promoter GO:0006366 80 0.028
regulation of rna metabolic process GO:0051252 224 0.028
positive regulation of metabolic process GO:0009893 108 0.028
superoxide metabolic process GO:0006801 2 0.028
erythrocyte differentiation GO:0030218 54 0.027
immune system development GO:0002520 191 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
negative regulation of catabolic process GO:0009895 3 0.026
regulation of autophagy GO:0010506 3 0.025
negative regulation of cellular process GO:0048523 283 0.025
cellular amide metabolic process GO:0043603 4 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
embryonic organ morphogenesis GO:0048562 274 0.024
heart development GO:0007507 313 0.024
response to external stimulus GO:0009605 264 0.024
cell death in response to oxidative stress GO:0036473 2 0.024
fin regeneration GO:0031101 51 0.024
protein import into nucleus GO:0006606 3 0.023
peptidyl serine modification GO:0018209 2 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
positive regulation of cell cycle GO:0045787 3 0.023
secondary metabolic process GO:0019748 3 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
positive regulation of transport GO:0051050 2 0.023
cellular response to organic substance GO:0071310 105 0.022
toll like receptor signaling pathway GO:0002224 4 0.022
ear development GO:0043583 127 0.022
peptidyl serine phosphorylation GO:0018105 1 0.022
response to endogenous stimulus GO:0009719 83 0.021
apoptotic process GO:0006915 116 0.021
response to inorganic substance GO:0010035 38 0.021
response to metal ion GO:0010038 34 0.021
regulation of protein transport GO:0051223 3 0.021
intracellular signal transduction GO:0035556 85 0.021
generation of neurons GO:0048699 385 0.021
response to bacterium GO:0009617 58 0.021
alcohol biosynthetic process GO:0046165 2 0.021
regulation of membrane potential GO:0042391 23 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
regulation of cellular response to oxidative stress GO:1900407 2 0.020
regulation of programmed cell death GO:0043067 101 0.020
transmembrane transport GO:0055085 120 0.020
multicellular organism growth GO:0035264 4 0.020
regulation of dna replication GO:0006275 3 0.020
regulation of oxidative stress induced cell death GO:1903201 2 0.020
amine metabolic process GO:0009308 2 0.020
nucleic acid metabolic process GO:0090304 244 0.020
negative regulation of metabolic process GO:0009892 86 0.020
regulation of cytokine production GO:0001817 3 0.019
protein metabolic process GO:0019538 183 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
response to abiotic stimulus GO:0009628 122 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
response to organic substance GO:0010033 153 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
myeloid cell differentiation GO:0030099 86 0.019
cell death GO:0008219 121 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
regulation of wound healing GO:0061041 2 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
cellular component morphogenesis GO:0032989 336 0.018
developmental growth GO:0048589 166 0.018
cellular transition metal ion homeostasis GO:0046916 3 0.018
homeostasis of number of cells GO:0048872 62 0.018
regulation of metal ion transport GO:0010959 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
cation homeostasis GO:0055080 33 0.018
system process GO:0003008 185 0.018
cell morphogenesis GO:0000902 289 0.018
hemopoiesis GO:0030097 183 0.018
nuclear transport GO:0051169 4 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
positive regulation of nucleic acid templated transcription GO:1903508 57 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
response to corticosteroid GO:0031960 1 0.017
peptide metabolic process GO:0006518 1 0.017
protein localization to nucleus GO:0034504 3 0.017
blood vessel morphogenesis GO:0048514 216 0.017
nuclear export GO:0051168 1 0.017
regulation of inflammatory response GO:0050727 2 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
iron ion homeostasis GO:0055072 4 0.016
single organism nuclear import GO:1902593 3 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
cytokinesis GO:0000910 3 0.016
regulation of blood vessel size GO:0050880 2 0.016
nuclear import GO:0051170 3 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of response to oxidative stress GO:1902882 2 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
negative regulation of rna metabolic process GO:0051253 48 0.015
regulation of cell death GO:0010941 103 0.015
behavior GO:0007610 74 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
digestive system development GO:0055123 289 0.015
neurological system process GO:0050877 62 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
gtp catabolic process GO:0006184 2 0.015
nitric oxide biosynthetic process GO:0006809 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
regulation of protein targeting GO:1903533 2 0.015
cell projection morphogenesis GO:0048858 244 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
protein stabilization GO:0050821 2 0.014
rna metabolic process GO:0016070 219 0.014
neuron development GO:0048666 262 0.014
adult behavior GO:0030534 2 0.014
cell migration GO:0016477 237 0.014
regulation of developmental process GO:0050793 247 0.014
sensory organ morphogenesis GO:0090596 200 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
positive regulation of cellular process GO:0048522 201 0.014
response to organic cyclic compound GO:0014070 51 0.014
cellular component movement GO:0006928 335 0.014
cellular ketone metabolic process GO:0042180 11 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
response to ketone GO:1901654 1 0.014
taxis GO:0042330 109 0.014
cellular protein catabolic process GO:0044257 4 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
defense response GO:0006952 47 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
response to hydrogen peroxide GO:0042542 3 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.013
multi organism process GO:0051704 134 0.013
sensory perception of smell GO:0007608 2 0.013
muscle cell differentiation GO:0042692 139 0.013
regulation of cell shape GO:0008360 1 0.013
pyruvate metabolic process GO:0006090 1 0.013
multicellular organismal response to stress GO:0033555 2 0.013
regulation of tube size GO:0035150 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of jun kinase activity GO:0043506 3 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
pancreas development GO:0031016 84 0.012
digestive tract morphogenesis GO:0048546 231 0.012
fat soluble vitamin metabolic process GO:0006775 4 0.012
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.012
anion transmembrane transport GO:0098656 12 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
porphyrin containing compound metabolic process GO:0006778 10 0.012
regulation of reproductive process GO:2000241 4 0.012
cell part morphogenesis GO:0032990 246 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regeneration GO:0031099 91 0.012
positive regulation of cell activation GO:0050867 1 0.012
axonogenesis GO:0007409 152 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
regulation of cell activation GO:0050865 1 0.011
cation transmembrane transport GO:0098655 65 0.011
ion transport GO:0006811 114 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
gastrulation GO:0007369 208 0.011
response to oxygen radical GO:0000305 2 0.011
gtp metabolic process GO:0046039 4 0.011
tissue regeneration GO:0042246 74 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
signal transduction GO:0007165 455 0.011
cofactor metabolic process GO:0051186 15 0.011
metal ion homeostasis GO:0055065 26 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
wound healing GO:0042060 90 0.011
startle response GO:0001964 4 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
central nervous system development GO:0007417 387 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
negative regulation of cell proliferation GO:0008285 8 0.010
carbohydrate homeostasis GO:0033500 1 0.010
neuron projection morphogenesis GO:0048812 161 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
small molecule catabolic process GO:0044282 3 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
cellular response to external stimulus GO:0071496 2 0.010
organonitrogen compound biosynthetic process GO:1901566 47 0.010
establishment of localization GO:0051234 244 0.010
erythrocyte development GO:0048821 24 0.010
stem cell maintenance GO:0019827 4 0.010
cellular response to oxygen containing compound GO:1901701 20 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010

gpx1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016