Danio rerio

0 known processes

htr1ab

5-hydroxytryptamine (serotonin) receptor 1A b

htr1ab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sleep GO:0030431 1 0.237
monoamine transport GO:0015844 1 0.180
Mouse
positive regulation of cell cycle GO:0045787 3 0.119
nitrogen compound metabolic process GO:0006807 319 0.101
Zebrafish Mouse
purine containing compound biosynthetic process GO:0072522 20 0.100
Zebrafish
membrane hyperpolarization GO:0060081 1 0.097
catecholamine metabolic process GO:0006584 2 0.097
Mouse
hormone transport GO:0009914 2 0.096
circulatory system process GO:0003013 87 0.092
Zebrafish
response to chemical GO:0042221 320 0.088
regulation of circadian rhythm GO:0042752 4 0.085
embryonic organ morphogenesis GO:0048562 274 0.081
cognition GO:0050890 1 0.077
sensory organ development GO:0007423 393 0.077
urogenital system development GO:0001655 97 0.076
circadian sleep wake cycle GO:0042745 2 0.071
primary amino compound metabolic process GO:1901160 1 0.069
Mouse
g protein coupled receptor signaling pathway GO:0007186 74 0.069
Human Zebrafish Mouse Rat
catechol containing compound metabolic process GO:0009712 2 0.064
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.062
Zebrafish Mouse
ear morphogenesis GO:0042471 64 0.062
circadian sleep wake cycle sleep GO:0050802 1 0.061
regulation of endocrine process GO:0044060 2 0.060
positive regulation of secretion by cell GO:1903532 1 0.058
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.056
sequestering of metal ion GO:0051238 3 0.056
blood circulation GO:0008015 87 0.055
Zebrafish
steroid hormone secretion GO:0035929 1 0.054
catechol containing compound biosynthetic process GO:0009713 2 0.054
response to organic substance GO:0010033 153 0.053
digestive tract morphogenesis GO:0048546 231 0.052
digestive system development GO:0055123 289 0.051
hormone secretion GO:0046879 2 0.050
camera type eye development GO:0043010 222 0.049
multicellular organism growth GO:0035264 4 0.049
biosynthetic process GO:0009058 294 0.047
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.047
Zebrafish
heterocycle metabolic process GO:0046483 290 0.046
Zebrafish Mouse
sequestering of calcium ion GO:0051208 3 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.045
positive regulation of transport GO:0051050 2 0.045
indole containing compound metabolic process GO:0042430 2 0.043
Mouse
negative regulation of biological process GO:0048519 304 0.041
Zebrafish Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.039
Zebrafish
maintenance of location GO:0051235 4 0.039
cellular biosynthetic process GO:0044249 286 0.039
Zebrafish
larval development GO:0002164 2 0.038
negative regulation of hormone secretion GO:0046888 2 0.038
glucose homeostasis GO:0042593 1 0.038
cellular amide metabolic process GO:0043603 4 0.037
olfactory lobe development GO:0021988 4 0.036
circadian sleep wake cycle process GO:0022410 2 0.036
inner ear development GO:0048839 126 0.036
embryonic organ development GO:0048568 381 0.036
cellular amine metabolic process GO:0044106 2 0.035
Mouse
regulation of reproductive process GO:2000241 4 0.034
sensory system development GO:0048880 76 0.034
female gonad development GO:0008585 4 0.034
regulation of cytokine production GO:0001817 3 0.033
regulation of ion transmembrane transporter activity GO:0032412 2 0.033
system process GO:0003008 185 0.033
Zebrafish
negative regulation of sequestering of calcium ion GO:0051283 4 0.033
regulation of hormone secretion GO:0046883 2 0.032
cell surface receptor signaling pathway GO:0007166 325 0.032
Human Zebrafish Mouse Rat
regulation of programmed cell death GO:0043067 101 0.031
regulation of ph GO:0006885 3 0.031
positive regulation of secretion GO:0051047 1 0.031
optomotor response GO:0071632 1 0.030
negative regulation of secretion GO:0051048 2 0.030
neuron neuron synaptic transmission GO:0007270 1 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Zebrafish Mouse
regulation of circadian sleep wake cycle GO:0042749 1 0.029
phagocytosis GO:0006909 3 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.029
regulation of biosynthetic process GO:0009889 250 0.029
Zebrafish
cellular response to radiation GO:0071478 4 0.028
apoptotic process GO:0006915 116 0.028
purine ribonucleotide biosynthetic process GO:0009152 20 0.028
Zebrafish
myeloid cell differentiation GO:0030099 86 0.028
cellular response to estrogen stimulus GO:0071391 24 0.027
organonitrogen compound biosynthetic process GO:1901566 47 0.027
Zebrafish
lateral line development GO:0048882 66 0.027
homeostatic process GO:0042592 142 0.027
organic substance biosynthetic process GO:1901576 289 0.027
Zebrafish
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.027
membrane invagination GO:0010324 1 0.026
digestive tract development GO:0048565 265 0.026
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.026
ear development GO:0043583 127 0.026
stem cell maintenance GO:0019827 4 0.025
female sex differentiation GO:0046660 4 0.025
positive regulation of cytoskeleton organization GO:0051495 3 0.025
Rat
signal transduction GO:0007165 455 0.025
Human Zebrafish Mouse Rat
cellular protein catabolic process GO:0044257 4 0.025
cellular component disassembly GO:0022411 1 0.025
Rat
regulation of synapse assembly GO:0051963 3 0.025
positive regulation of map kinase activity GO:0043406 3 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.024
Zebrafish
modification dependent macromolecule catabolic process GO:0043632 3 0.024
regulation of sequestering of calcium ion GO:0051282 4 0.024
ribose phosphate biosynthetic process GO:0046390 20 0.024
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.024
regulation of multicellular organism growth GO:0040014 4 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
lateral line system development GO:0048925 76 0.022
regulation of postsynaptic membrane potential GO:0060078 1 0.022
tube morphogenesis GO:0035239 349 0.022
single organism membrane fusion GO:0044801 2 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
Zebrafish
ion homeostasis GO:0050801 41 0.022
single organism metabolic process GO:0044710 217 0.022
Zebrafish
heart process GO:0003015 71 0.022
Zebrafish
purine nucleotide biosynthetic process GO:0006164 20 0.022
Zebrafish
myeloid cell development GO:0061515 32 0.022
development of primary female sexual characteristics GO:0046545 4 0.021
programmed cell death GO:0012501 119 0.021
membrane fusion GO:0061025 2 0.021
compound eye development GO:0048749 2 0.021
dopamine metabolic process GO:0042417 2 0.021
Mouse
endocrine process GO:0050886 2 0.020
phasic smooth muscle contraction GO:0014821 1 0.020
single organism organelle organization GO:1902589 199 0.020
Rat
ovulation cycle process GO:0022602 2 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
carbon dioxide transport GO:0015670 3 0.020
regulation of nucleotide biosynthetic process GO:0030808 15 0.020
Zebrafish
gabaergic neuron differentiation GO:0097154 2 0.020
organophosphate biosynthetic process GO:0090407 23 0.020
Zebrafish
olfactory bulb development GO:0021772 4 0.020
regulation of steroid hormone secretion GO:2000831 1 0.020
phagocytosis engulfment GO:0006911 1 0.020
regulation of signaling GO:0023051 235 0.019
startle response GO:0001964 4 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of blood pressure GO:0008217 1 0.019
cyclic nucleotide metabolic process GO:0009187 18 0.019
Zebrafish
dopamine biosynthetic process GO:0042416 2 0.019
membrane lipid biosynthetic process GO:0046467 2 0.019
organonitrogen compound metabolic process GO:1901564 74 0.018
Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.018
Zebrafish
aging GO:0007568 2 0.018
kidney development GO:0001822 92 0.018
amino acid transport GO:0006865 2 0.018
skeletal system development GO:0001501 181 0.018
regulation of protein complex assembly GO:0043254 3 0.018
pigment granule localization GO:0051875 25 0.018
nucleotide biosynthetic process GO:0009165 21 0.018
Zebrafish
small molecule metabolic process GO:0044281 77 0.018
Zebrafish
regulation of lipase activity GO:0060191 2 0.018
cellular response to light stimulus GO:0071482 4 0.018
positive regulation of catabolic process GO:0009896 4 0.018
endocrine hormone secretion GO:0060986 2 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
hemopoiesis GO:0030097 183 0.017
immune system development GO:0002520 191 0.017
positive regulation of cell communication GO:0010647 56 0.017
axon development GO:0061564 166 0.017
cellular pigmentation GO:0033059 30 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
multicellular organismal response to stress GO:0033555 2 0.017
Mouse
regulation of synaptic plasticity GO:0048167 1 0.017
regulation of cyclase activity GO:0031279 12 0.017
Zebrafish
posterior lateral line development GO:0048916 38 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
Zebrafish Mouse
positive regulation of camp biosynthetic process GO:0030819 2 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
melanosome localization GO:0032400 21 0.016
regulation of metal ion transport GO:0010959 4 0.016
protein polymerization GO:0051258 4 0.016
renal system development GO:0072001 94 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
positive regulation of lipid metabolic process GO:0045834 1 0.016
regulation of transporter activity GO:0032409 2 0.016
response to hormone GO:0009725 48 0.016
regulation of synapse organization GO:0050807 3 0.015
actin filament polymerization GO:0030041 2 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of fatty acid metabolic process GO:0019217 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
response to amphetamine GO:0001975 1 0.015
cytoskeleton organization GO:0007010 96 0.015
Rat
spinal cord motor neuron differentiation GO:0021522 26 0.015
lipid metabolic process GO:0006629 52 0.015
regulation of muscle contraction GO:0006937 3 0.015
thermosensory behavior GO:0040040 1 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
catecholamine biosynthetic process GO:0042423 2 0.015
response to dexamethasone GO:0071548 1 0.014
regulation of cell death GO:0010941 103 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
auditory receptor cell fate specification GO:0042667 2 0.014
ovulation cycle GO:0042698 2 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
regulation of biological quality GO:0065008 263 0.014
Zebrafish
erythrocyte development GO:0048821 24 0.014
somatic muscle development GO:0007525 4 0.014
regulation of neurological system process GO:0031644 2 0.014
rhodopsin mediated signaling pathway GO:0016056 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
organic acid metabolic process GO:0006082 31 0.014
epidermal cell fate specification GO:0009957 4 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
posterior lateral line system development GO:0048915 46 0.014
pronuclear migration GO:0035046 1 0.014
negative regulation of camp biosynthetic process GO:0030818 7 0.014
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.014
synaptic transmission glycinergic GO:0060012 1 0.014
serotonin biosynthetic process GO:0042427 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
rna biosynthetic process GO:0032774 181 0.013
erythrocyte differentiation GO:0030218 54 0.013
cellular ketone metabolic process GO:0042180 11 0.013
phosphorus metabolic process GO:0006793 109 0.013
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.013
negative regulation of catabolic process GO:0009895 3 0.013
eye development GO:0001654 277 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
heart development GO:0007507 313 0.013
axis elongation GO:0003401 31 0.013
cellular component movement GO:0006928 335 0.013
serotonin metabolic process GO:0042428 1 0.013
Mouse
positive regulation of camp metabolic process GO:0030816 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
cell migration GO:0016477 237 0.013
phenol containing compound biosynthetic process GO:0046189 4 0.013
regulation of oocyte development GO:0060281 3 0.013
water homeostasis GO:0030104 4 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
skeletal system morphogenesis GO:0048705 102 0.013
smooth muscle contraction GO:0006939 2 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
cell death GO:0008219 121 0.012
regulation of protein catabolic process GO:0042176 1 0.012
mechanosensory lateral line system development GO:0048881 49 0.012
androgen metabolic process GO:0008209 2 0.012
camp metabolic process GO:0046058 11 0.012
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.012
Mouse
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.012
Zebrafish
organelle fusion GO:0048284 3 0.012
intracellular signal transduction GO:0035556 85 0.012
nuclear migration GO:0007097 3 0.012
phototransduction GO:0007602 2 0.012
organelle organization GO:0006996 227 0.012
Rat
response to oxygen containing compound GO:1901700 55 0.012
cilium morphogenesis GO:0060271 85 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
Zebrafish
heart contraction GO:0060047 71 0.012
Zebrafish
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
forebrain neuron development GO:0021884 7 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
skin development GO:0043588 54 0.012
organic hydroxy compound transport GO:0015850 14 0.012
Mouse
muscle hypertrophy GO:0014896 2 0.012
forebrain regionalization GO:0021871 4 0.012
oxoacid metabolic process GO:0043436 31 0.012
cell part morphogenesis GO:0032990 246 0.011
activation of mapk activity GO:0000187 3 0.011
response to topologically incorrect protein GO:0035966 2 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
regulation of cellular ph GO:0030641 1 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
regulation of wound healing GO:0061041 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
establishment of localization GO:0051234 244 0.011
Mouse
single organism behavior GO:0044708 24 0.011
Mouse
positive regulation of metabolic process GO:0009893 108 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
Zebrafish
inner ear morphogenesis GO:0042472 63 0.011
positive regulation of cell division GO:0051781 2 0.011
nitric oxide metabolic process GO:0046209 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
organic substance transport GO:0071702 58 0.011
Mouse
cell morphogenesis GO:0000902 289 0.011
regulation of lipid transport GO:0032368 4 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of cell activation GO:0050865 1 0.011
response to ketone GO:1901654 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
energy reserve metabolic process GO:0006112 2 0.011
hormone mediated signaling pathway GO:0009755 9 0.011
positive regulation of biological process GO:0048518 253 0.011
Rat
negative regulation of defense response GO:0031348 2 0.011
peptide transport GO:0015833 1 0.011
primary amino compound biosynthetic process GO:1901162 1 0.011
lymphoid lineage cell migration GO:0097534 4 0.011
cellular response to estradiol stimulus GO:0071392 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cell projection organization GO:0030030 284 0.010
amide transport GO:0042886 12 0.010
negative regulation of cytokine production GO:0001818 1 0.010
response to glucocorticoid GO:0051384 1 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
spindle assembly GO:0051225 2 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
gtp catabolic process GO:0006184 2 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.010
Zebrafish
specification of organ identity GO:0010092 2 0.010
response to estrogen GO:0043627 27 0.010
protein localization to nucleus GO:0034504 3 0.010
positive regulation of reproductive process GO:2000243 2 0.010
protein metabolic process GO:0019538 183 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
protein modification process GO:0036211 100 0.010
regulation of phospholipase activity GO:0010517 2 0.010
cytokinesis GO:0000910 3 0.010
response to hexose GO:0009746 3 0.010

htr1ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
disease of anatomical entity DOID:7 0 0.023
Human
organ system cancer DOID:0050686 0 0.021
musculoskeletal system disease DOID:17 0 0.013