Danio rerio

0 known processes

efna1a

ephrin A1a

(Aliases: zgc:63493,MGC63493)

efna1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of location GO:0051235 4 0.044
cellular amine metabolic process GO:0044106 2 0.042
larval development GO:0002164 2 0.040
positive regulation of transport GO:0051050 2 0.037
amine metabolic process GO:0009308 2 0.037
regulation of sequestering of calcium ion GO:0051282 4 0.035
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.029
cellular ketone metabolic process GO:0042180 11 0.029
cellular response to external stimulus GO:0071496 2 0.028
regulation of cytokine production GO:0001817 3 0.028
central nervous system development GO:0007417 387 0.028
nuclear transport GO:0051169 4 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
aging GO:0007568 2 0.027
stem cell proliferation GO:0072089 4 0.027
regulation of protein complex assembly GO:0043254 3 0.027
establishment of protein localization to organelle GO:0072594 4 0.026
response to drug GO:0042493 3 0.026
biosynthetic process GO:0009058 294 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
stem cell maintenance GO:0019827 4 0.026
lipid storage GO:0019915 1 0.026
phagocytosis GO:0006909 3 0.026
cellular component morphogenesis GO:0032989 336 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
multicellular organism growth GO:0035264 4 0.024
positive regulation of catabolic process GO:0009896 4 0.024
cellular response to starvation GO:0009267 1 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
release of sequestered calcium ion into cytosol GO:0051209 3 0.024
negative regulation of sequestering of calcium ion GO:0051283 4 0.024
protein import GO:0017038 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
positive regulation of cell cycle GO:0045787 3 0.023
signal transduction GO:0007165 455 0.023
organic acid metabolic process GO:0006082 31 0.023
immune system process GO:0002376 241 0.023
response to chemical GO:0042221 320 0.023
actin polymerization or depolymerization GO:0008154 2 0.023
regulation of protein catabolic process GO:0042176 1 0.023
protein polymerization GO:0051258 4 0.022
response to carbohydrate GO:0009743 3 0.022
head development GO:0060322 303 0.022
regulation of signaling GO:0023051 235 0.022
protein localization to nucleus GO:0034504 3 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
protein heterooligomerization GO:0051291 1 0.022
cellular response to nutrient levels GO:0031669 2 0.021
cell projection organization GO:0030030 284 0.021
gtp metabolic process GO:0046039 4 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
regulation of reproductive process GO:2000241 4 0.021
single organism metabolic process GO:0044710 217 0.021
membrane fusion GO:0061025 2 0.020
oxoacid metabolic process GO:0043436 31 0.020
autophagy GO:0006914 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
cellular protein catabolic process GO:0044257 4 0.020
regulation of inflammatory response GO:0050727 2 0.020
cell projection morphogenesis GO:0048858 244 0.020
response to uv GO:0009411 3 0.020
regulation of signal transduction GO:0009966 225 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
regulation of developmental process GO:0050793 247 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
cellular biosynthetic process GO:0044249 286 0.019
positive regulation of cytokine production GO:0001819 2 0.019
regulation of cell activation GO:0050865 1 0.019
protein import into nucleus GO:0006606 3 0.019
tube morphogenesis GO:0035239 349 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
adult behavior GO:0030534 2 0.019
sequestering of metal ion GO:0051238 3 0.019
female sex differentiation GO:0046660 4 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
regulation of mrna processing GO:0050684 3 0.019
regulation of response to stimulus GO:0048583 269 0.019
cell part morphogenesis GO:0032990 246 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
regulation of metabolic process GO:0019222 359 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
regulation of metal ion transport GO:0010959 4 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of autophagy GO:0010506 3 0.018
heterocycle metabolic process GO:0046483 290 0.018
leukocyte proliferation GO:0070661 1 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
brain development GO:0007420 293 0.018
protein targeting to nucleus GO:0044744 3 0.018
cellular component movement GO:0006928 335 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.018
regulation of cell projection assembly GO:0060491 4 0.018
organelle fusion GO:0048284 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
tissue remodeling GO:0048771 4 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
meiotic nuclear division GO:0007126 4 0.017
gtp catabolic process GO:0006184 2 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
cell morphogenesis GO:0000902 289 0.017
regulation of binding GO:0051098 3 0.017
regulation of protein polymerization GO:0032271 2 0.017
blood vessel development GO:0001568 246 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
immune system development GO:0002520 191 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
cellular component disassembly GO:0022411 1 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
regulation of biological quality GO:0065008 263 0.017
regulation of tube size GO:0035150 2 0.017
protein metabolic process GO:0019538 183 0.017
neuroblast proliferation GO:0007405 2 0.017
protein acetylation GO:0006473 2 0.016
female gonad development GO:0008585 4 0.016
response to stress GO:0006950 263 0.016
response to external stimulus GO:0009605 264 0.016
calcium ion transport into cytosol GO:0060402 3 0.016
hormone secretion GO:0046879 2 0.016
stem cell division GO:0017145 1 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
rna metabolic process GO:0016070 219 0.016
vasculature development GO:0001944 278 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
nuclear migration GO:0007097 3 0.016
b cell activation GO:0042113 2 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
small molecule metabolic process GO:0044281 77 0.016
positive regulation of secretion GO:0051047 1 0.016
generation of neurons GO:0048699 385 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
meiotic cell cycle process GO:1903046 3 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
peptide transport GO:0015833 1 0.016
skeletal system development GO:0001501 181 0.016
regulation of blood vessel size GO:0050880 2 0.016
cell migration GO:0016477 237 0.016
regulation of synapse assembly GO:0051963 3 0.016
secondary metabolic process GO:0019748 3 0.015
cognition GO:0050890 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of protein transport GO:0051223 3 0.015
negative regulation of catabolic process GO:0009895 3 0.015
cell motility GO:0048870 244 0.015
organelle organization GO:0006996 227 0.015
embryonic organ development GO:0048568 381 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
single organism localization GO:1902578 225 0.015
gene expression GO:0010467 252 0.015
regulation of protein targeting GO:1903533 2 0.015
mitochondrion organization GO:0007005 4 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
chordate embryonic development GO:0043009 271 0.015
locomotion GO:0040011 313 0.015
regulation of blood pressure GO:0008217 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
single organism organelle organization GO:1902589 199 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
positive regulation of protein complex assembly GO:0031334 2 0.014
eye development GO:0001654 277 0.014
nuclear import GO:0051170 3 0.014
negative regulation of biological process GO:0048519 304 0.014
single organism transport GO:0044765 206 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
negative regulation of cellular process GO:0048523 283 0.014
lipid homeostasis GO:0055088 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
organic substance biosynthetic process GO:1901576 289 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
cellular response to radiation GO:0071478 4 0.014
mononuclear cell proliferation GO:0032943 1 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
transport GO:0006810 220 0.014
atp catabolic process GO:0006200 4 0.014
cellular response to oxygen levels GO:0071453 1 0.014
response to hexose GO:0009746 3 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
cytokinesis GO:0000910 3 0.014
positive regulation of biological process GO:0048518 253 0.014
neuron differentiation GO:0030182 353 0.014
regulation of transporter activity GO:0032409 2 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of dendrite development GO:0050773 3 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
protein homooligomerization GO:0051260 3 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
single organism membrane fusion GO:0044801 2 0.014
meiotic chromosome segregation GO:0045132 3 0.014
transcription dna templated GO:0006351 181 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
angiogenesis GO:0001525 158 0.013
digestive tract development GO:0048565 265 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
response to corticosteroid GO:0031960 1 0.013
lamellipodium organization GO:0097581 1 0.013
growth GO:0040007 174 0.013
sensory system development GO:0048880 76 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
cellular component biogenesis GO:0044085 178 0.013
response to nutrient GO:0007584 3 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of ph GO:0006885 3 0.013
regulation of organ growth GO:0046620 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
protein localization to plasma membrane GO:0072659 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
actin filament polymerization GO:0030041 2 0.013
nuclear export GO:0051168 1 0.013
establishment of localization GO:0051234 244 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of biosynthetic process GO:0009889 250 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
chemotaxis GO:0006935 104 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
single organism nuclear import GO:1902593 3 0.013
protein acylation GO:0043543 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
response to monosaccharide GO:0034284 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.012
negative regulation of rna splicing GO:0033119 1 0.012
tube closure GO:0060606 1 0.012
axonogenesis GO:0007409 152 0.012
digestive system development GO:0055123 289 0.012
regulation of gene expression GO:0010468 265 0.012
endosomal transport GO:0016197 2 0.012
protein dephosphorylation GO:0006470 3 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
trabecula morphogenesis GO:0061383 2 0.012
embryonic skeletal joint development GO:0072498 3 0.012
skeletal system morphogenesis GO:0048705 102 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
response to organic substance GO:0010033 153 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
protein stabilization GO:0050821 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
regulation of cell shape GO:0008360 1 0.012
neuron development GO:0048666 262 0.012
system process GO:0003008 185 0.012
regulation of muscle contraction GO:0006937 3 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
smooth muscle contraction GO:0006939 2 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of cytokine production GO:0001818 1 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cartilage development GO:0051216 96 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
post embryonic organ development GO:0048569 4 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
sequestering of calcium ion GO:0051208 3 0.012
regulation of synapse organization GO:0050807 3 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
protein complex disassembly GO:0043241 1 0.012
sensory organ development GO:0007423 393 0.012
compound eye development GO:0048749 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
mesenchyme development GO:0060485 127 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
connective tissue development GO:0061448 99 0.012
regulation of wound healing GO:0061041 2 0.012
immunoglobulin mediated immune response GO:0016064 3 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
lamellipodium assembly GO:0030032 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
transmembrane transport GO:0055085 120 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
adherens junction organization GO:0034332 4 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of cell communication GO:0010646 232 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
nephron morphogenesis GO:0072028 2 0.011
macromolecule modification GO:0043412 111 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
catecholamine metabolic process GO:0006584 2 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
synaptic target recognition GO:0008039 1 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
phagocytosis engulfment GO:0006911 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regionalization GO:0003002 274 0.011
notochord development GO:0030903 54 0.011
regulation of primary metabolic process GO:0080090 311 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cellular component assembly GO:0022607 170 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
membrane invagination GO:0010324 1 0.011
primary neural tube formation GO:0014020 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
embryonic skeletal system development GO:0048706 97 0.011
homeostatic process GO:0042592 142 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
somite development GO:0061053 96 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
negative regulation of defense response GO:0031348 2 0.011
axon development GO:0061564 166 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
hormone transport GO:0009914 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
protein modification process GO:0036211 100 0.011
anterior posterior pattern specification GO:0009952 152 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
complement activation GO:0006956 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
toxin transport GO:1901998 2 0.011
wnt signaling pathway GO:0016055 80 0.011
positive regulation of cellular process GO:0048522 201 0.010
response to topologically incorrect protein GO:0035966 2 0.010
exocytosis GO:0006887 1 0.010
positive regulation of blood circulation GO:1903524 2 0.010
positive regulation of muscle tissue development GO:1901863 1 0.010
negative regulation of signaling GO:0023057 96 0.010
synaptic vesicle localization GO:0097479 1 0.010
neuron projection guidance GO:0097485 86 0.010
positive regulation of cell activation GO:0050867 1 0.010
developmental growth GO:0048589 166 0.010
lymphocyte proliferation GO:0046651 1 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
protein polyubiquitination GO:0000209 4 0.010
camera type eye development GO:0043010 222 0.010
ameboidal type cell migration GO:0001667 143 0.010
small molecule catabolic process GO:0044282 3 0.010
localization of cell GO:0051674 244 0.010

efna1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
organ system cancer DOID:0050686 0 0.011