Danio rerio

0 known processes

sepp1a

selenoprotein P, plasma, 1a

(Aliases: cb688,SelPa,SePPa,wu:fa55a04,wu:fj79f04,wu:fb38a09)

sepp1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biological process GO:0048519 304 0.627
cellular response to endogenous stimulus GO:0071495 68 0.350
hemopoiesis GO:0030097 183 0.323
nitrogen compound metabolic process GO:0006807 319 0.304
regulation of primary metabolic process GO:0080090 311 0.269
regulation of macromolecule metabolic process GO:0060255 317 0.267
regulation of nucleic acid templated transcription GO:1903506 213 0.221
regulation of nitrogen compound metabolic process GO:0051171 251 0.205
regulation of developmental process GO:0050793 247 0.201
cellular nitrogen compound metabolic process GO:0034641 290 0.199
regulation of gene expression GO:0010468 265 0.197
positive regulation of metabolic process GO:0009893 108 0.187
response to chemical GO:0042221 320 0.183
regulation of metabolic process GO:0019222 359 0.159
response to steroid hormone GO:0048545 35 0.157
organic substance biosynthetic process GO:1901576 289 0.156
cellular macromolecule metabolic process GO:0044260 391 0.155
aromatic compound biosynthetic process GO:0019438 217 0.149
cellular biosynthetic process GO:0044249 286 0.149
immune system process GO:0002376 241 0.148
growth GO:0040007 174 0.147
regulation of cellular biosynthetic process GO:0031326 245 0.147
gene expression GO:0010467 252 0.145
neuron development GO:0048666 262 0.143
response to xenobiotic stimulus GO:0009410 45 0.143
homeostatic process GO:0042592 142 0.142
glial cell migration GO:0008347 3 0.142
multicellular organism growth GO:0035264 4 0.138
cellular nitrogen compound biosynthetic process GO:0044271 218 0.133
immune system development GO:0002520 191 0.128
response to copper ion GO:0046688 13 0.126
cell surface receptor signaling pathway GO:0007166 325 0.122
negative regulation of cellular process GO:0048523 283 0.122
regulation of rna metabolic process GO:0051252 224 0.117
regulation of cellular metabolic process GO:0031323 320 0.112
head development GO:0060322 303 0.112
regulation of multicellular organism growth GO:0040014 4 0.111
cellular response to xenobiotic stimulus GO:0071466 35 0.110
response to corticosteroid GO:0031960 1 0.096
rna biosynthetic process GO:0032774 181 0.096
regulation of biological quality GO:0065008 263 0.094
heterocycle biosynthetic process GO:0018130 215 0.093
response to abiotic stimulus GO:0009628 122 0.090
developmental growth GO:0048589 166 0.090
regulation of biosynthetic process GO:0009889 250 0.089
nucleic acid metabolic process GO:0090304 244 0.087
larval development GO:0002164 2 0.085
cellular component morphogenesis GO:0032989 336 0.085
rna metabolic process GO:0016070 219 0.084
single organism localization GO:1902578 225 0.084
establishment of localization GO:0051234 244 0.083
regulation of cell differentiation GO:0045595 142 0.083
single organism transport GO:0044765 206 0.081
transmembrane transport GO:0055085 120 0.081
establishment of blood brain barrier GO:0060856 2 0.081
transcription dna templated GO:0006351 181 0.080
maintenance of location GO:0051235 4 0.080
regulation of synapse assembly GO:0051963 3 0.079
regulation of rna biosynthetic process GO:2001141 213 0.078
enzyme linked receptor protein signaling pathway GO:0007167 106 0.077
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.075
nucleobase containing compound biosynthetic process GO:0034654 205 0.074
embryonic organ development GO:0048568 381 0.069
signal transduction GO:0007165 455 0.068
cation transport GO:0006812 81 0.068
aging GO:0007568 2 0.068
synaptic growth at neuromuscular junction GO:0051124 2 0.067
response to stress GO:0006950 263 0.067
macromolecule biosynthetic process GO:0009059 227 0.066
neuron differentiation GO:0030182 353 0.066
biosynthetic process GO:0009058 294 0.066
segmentation GO:0035282 97 0.065
cellular amino acid metabolic process GO:0006520 7 0.065
camera type eye development GO:0043010 222 0.064
cellular response to chemical stimulus GO:0070887 157 0.064
heart development GO:0007507 313 0.064
neuron projection development GO:0031175 180 0.063
response to external stimulus GO:0009605 264 0.062
transport GO:0006810 220 0.062
regulation of dendrite development GO:0050773 3 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.061
digestive tract morphogenesis GO:0048546 231 0.061
organic cyclic compound metabolic process GO:1901360 301 0.059
taurine metabolic process GO:0019530 1 0.059
alpha amino acid metabolic process GO:1901605 3 0.059
cellular response to estrogen stimulus GO:0071391 24 0.058
cellular amine metabolic process GO:0044106 2 0.058
heterocycle metabolic process GO:0046483 290 0.058
organic acid metabolic process GO:0006082 31 0.057
lateral inhibition GO:0046331 1 0.057
cellular ketone metabolic process GO:0042180 11 0.057
positive regulation of cellular process GO:0048522 201 0.056
nucleic acid templated transcription GO:0097659 181 0.055
response to wounding GO:0009611 116 0.054
monovalent inorganic cation transport GO:0015672 42 0.054
cellular macromolecule biosynthetic process GO:0034645 224 0.053
regulation of signaling GO:0023051 235 0.053
regulation of synapse organization GO:0050807 3 0.052
regulation of catalytic activity GO:0050790 55 0.051
cellular aromatic compound metabolic process GO:0006725 295 0.050
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.050
response to hormone GO:0009725 48 0.050
positive regulation of macromolecule metabolic process GO:0010604 93 0.050
cell morphogenesis GO:0000902 289 0.050
regulation of multicellular organismal process GO:0051239 277 0.049
morphogenesis of an epithelium GO:0002009 333 0.048
single organism metabolic process GO:0044710 217 0.048
cell projection organization GO:0030030 284 0.047
positive regulation of cellular metabolic process GO:0031325 94 0.047
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.047
response to glucocorticoid GO:0051384 1 0.046
lipid storage GO:0019915 1 0.045
negative regulation of developmental process GO:0051093 65 0.045
positive regulation of catabolic process GO:0009896 4 0.045
regulation of transcription dna templated GO:0006355 213 0.045
cell death GO:0008219 121 0.044
neuron projection morphogenesis GO:0048812 161 0.044
blood vessel development GO:0001568 246 0.044
regulation of growth GO:0040008 42 0.043
connective tissue development GO:0061448 99 0.043
hematopoietic or lymphoid organ development GO:0048534 191 0.043
cell projection morphogenesis GO:0048858 244 0.043
ion transmembrane transport GO:0034220 91 0.042
generation of neurons GO:0048699 385 0.041
cell morphogenesis involved in differentiation GO:0000904 195 0.041
digestive tract development GO:0048565 265 0.041
cellular carbohydrate metabolic process GO:0044262 4 0.040
cell part morphogenesis GO:0032990 246 0.039
positive regulation of biological process GO:0048518 253 0.038
adult behavior GO:0030534 2 0.038
small molecule metabolic process GO:0044281 77 0.038
cellular response to organic substance GO:0071310 105 0.038
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.038
cellular response to lipid GO:0071396 39 0.038
reactive oxygen species metabolic process GO:0072593 6 0.037
regulation of nervous system development GO:0051960 90 0.037
negative regulation of cell communication GO:0010648 96 0.037
negative regulation of signaling GO:0023057 96 0.037
protein metabolic process GO:0019538 183 0.037
sensory organ morphogenesis GO:0090596 200 0.037
regulation of response to stimulus GO:0048583 269 0.037
energy reserve metabolic process GO:0006112 2 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.036
cellular modified amino acid metabolic process GO:0006575 3 0.036
neural crest cell differentiation GO:0014033 72 0.036
response to alkaloid GO:0043279 2 0.035
cellular transition metal ion homeostasis GO:0046916 3 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
axon development GO:0061564 166 0.033
phosphorylation GO:0016310 69 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
septum transversum development GO:0003343 4 0.033
proepicardium development GO:0003342 4 0.033
positive regulation of gene expression GO:0010628 71 0.033
determination of left right symmetry GO:0007368 179 0.032
pancreas development GO:0031016 84 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.032
taxis GO:0042330 109 0.032
receptor internalization GO:0031623 2 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
locomotion GO:0040011 313 0.031
regulation of protein binding GO:0043393 3 0.031
regulation of developmental growth GO:0048638 38 0.031
regulation of cell activation GO:0050865 1 0.030
cellular lipid metabolic process GO:0044255 36 0.030
organic acid catabolic process GO:0016054 3 0.030
negative regulation of leukocyte differentiation GO:1902106 1 0.030
alcohol biosynthetic process GO:0046165 2 0.030
regulation of protein metabolic process GO:0051246 56 0.029
central nervous system development GO:0007417 387 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
lipid homeostasis GO:0055088 3 0.028
cellular protein metabolic process GO:0044267 129 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.027
multicellular organismal response to stress GO:0033555 2 0.027
response to endogenous stimulus GO:0009719 83 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
negative regulation of signal transduction GO:0009968 94 0.027
response to food GO:0032094 1 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
eye development GO:0001654 277 0.027
regulation of multicellular organismal development GO:2000026 223 0.026
small gtpase mediated signal transduction GO:0007264 8 0.026
stem cell maintenance GO:0019827 4 0.026
cellular response to hormone stimulus GO:0032870 39 0.026
trabecula morphogenesis GO:0061383 2 0.026
response to organic cyclic compound GO:0014070 51 0.026
intracellular signal transduction GO:0035556 85 0.025
response to nutrient GO:0007584 3 0.025
brain development GO:0007420 293 0.025
phosphorus metabolic process GO:0006793 109 0.025
cellular response to oxygen containing compound GO:1901701 20 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.024
blood vessel morphogenesis GO:0048514 216 0.024
adherens junction organization GO:0034332 4 0.024
sodium ion transport GO:0006814 24 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.024
digestive system development GO:0055123 289 0.024
tube morphogenesis GO:0035239 349 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
gtp metabolic process GO:0046039 4 0.023
neurological system process GO:0050877 62 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
phagocytosis GO:0006909 3 0.022
cell proliferation GO:0008283 80 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
proteolysis GO:0006508 38 0.022
positive regulation of transport GO:0051050 2 0.022
convergent extension involved in gastrulation GO:0060027 71 0.021
regulation of neurogenesis GO:0050767 87 0.021
cell motility GO:0048870 244 0.021
cellular response to nutrient levels GO:0031669 2 0.021
gtp catabolic process GO:0006184 2 0.021
anterior posterior pattern specification GO:0009952 152 0.021
embryonic heart tube development GO:0035050 133 0.021
regulation of molecular function GO:0065009 70 0.021
activation of mapk activity GO:0000187 3 0.021
tissue remodeling GO:0048771 4 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
response to lipid GO:0033993 60 0.020
cellular response to starvation GO:0009267 1 0.020
vasculature development GO:0001944 278 0.020
cation homeostasis GO:0055080 33 0.020
positive regulation of cell cycle GO:0045787 3 0.020
neurotransmitter transport GO:0006836 2 0.020
sulfur compound metabolic process GO:0006790 13 0.020
response to organic substance GO:0010033 153 0.020
gland development GO:0048732 143 0.019
negative regulation of metabolic process GO:0009892 86 0.019
chemical homeostasis GO:0048878 49 0.019
carbohydrate biosynthetic process GO:0016051 1 0.019
dicarboxylic acid metabolic process GO:0043648 1 0.019
amine metabolic process GO:0009308 2 0.019
regulation of sodium ion transport GO:0002028 2 0.019
rna localization GO:0006403 4 0.019
cellular response to external stimulus GO:0071496 2 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.018
regulation of inflammatory response GO:0050727 2 0.018
regulation of cell death GO:0010941 103 0.018
regulation of protein catabolic process GO:0042176 1 0.018
negative regulation of cell death GO:0060548 60 0.018
positive regulation of catalytic activity GO:0043085 25 0.018
homeostasis of number of cells GO:0048872 62 0.018
branched chain amino acid metabolic process GO:0009081 1 0.018
retina development in camera type eye GO:0060041 146 0.018
cellular component movement GO:0006928 335 0.018
single organism biosynthetic process GO:0044711 71 0.018
regulation of programmed cell death GO:0043067 101 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
regulation of hormone secretion GO:0046883 2 0.017
cellular aldehyde metabolic process GO:0006081 4 0.017
protein localization to plasma membrane GO:0072659 1 0.017
negative regulation of defense response GO:0031348 2 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
multicellular organismal metabolic process GO:0044236 2 0.017
regulation of lipid transport GO:0032368 4 0.017
regulation of phosphate metabolic process GO:0019220 43 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
angiogenesis GO:0001525 158 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
sensory organ development GO:0007423 393 0.016
type b pancreatic cell development GO:0003323 4 0.016
response to oxygen containing compound GO:1901700 55 0.016
regulation of cell development GO:0060284 100 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
erythrocyte homeostasis GO:0034101 55 0.016
regulation of dna replication GO:0006275 3 0.016
cartilage development GO:0051216 96 0.016
response to hexose GO:0009746 3 0.016
regulation of cytokine production GO:0001817 3 0.016
cellular amide metabolic process GO:0043603 4 0.016
camera type eye morphogenesis GO:0048593 108 0.016
response to biotic stimulus GO:0009607 97 0.015
heart morphogenesis GO:0003007 156 0.015
carboxylic acid catabolic process GO:0046395 3 0.015
death GO:0016265 121 0.015
liver development GO:0001889 96 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
macromolecule modification GO:0043412 111 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
neuron death GO:0070997 21 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
protein homooligomerization GO:0051260 3 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
ion homeostasis GO:0050801 41 0.015
regulation of apoptotic process GO:0042981 98 0.015
myeloid cell differentiation GO:0030099 86 0.014
neuronal action potential GO:0019228 18 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
response to hypoxia GO:0001666 25 0.014
response to glucose GO:0009749 3 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of immune system process GO:0002682 34 0.014
cardiac muscle tissue development GO:0048738 48 0.014
regulation of endothelial cell proliferation GO:0001936 1 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
gliogenesis GO:0042063 45 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
cellular response to steroid hormone stimulus GO:0071383 31 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
defense response to other organism GO:0098542 33 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of establishment of planar polarity GO:0090175 4 0.013
posttranscriptional regulation of gene expression GO:0010608 14 0.013
pole plasm assembly GO:0007315 4 0.013
organelle fusion GO:0048284 3 0.013
regulation of reproductive process GO:2000241 4 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
somite development GO:0061053 96 0.013
glucocorticoid metabolic process GO:0008211 2 0.013
skeletal system morphogenesis GO:0048705 102 0.013
regulation of signal transduction GO:0009966 225 0.013
cellular protein catabolic process GO:0044257 4 0.013
ion transport GO:0006811 114 0.013
bmp signaling pathway GO:0030509 52 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
small molecule catabolic process GO:0044282 3 0.013
membrane fusion GO:0061025 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of blood pressure GO:0008217 1 0.013
regulation of autophagy GO:0010506 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
hindbrain development GO:0030902 91 0.013
autophagy GO:0006914 4 0.013
response to transition metal nanoparticle GO:1990267 28 0.013
regulation of cellular component organization GO:0051128 86 0.013
response to extracellular stimulus GO:0009991 10 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
determination of bilateral symmetry GO:0009855 204 0.012
response to drug GO:0042493 3 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
negative regulation of developmental growth GO:0048640 9 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
peptidyl serine modification GO:0018209 2 0.012
transmission of nerve impulse GO:0019226 19 0.012
cellular respiration GO:0045333 3 0.012
response to estrogen GO:0043627 27 0.012
long chain fatty acid transport GO:0015909 1 0.012
negative regulation of gene expression GO:0010629 65 0.012
system process GO:0003008 185 0.012
determination of dorsal ventral asymmetry GO:0048262 34 0.012
rhombomere 5 development GO:0021571 4 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
cellular response to prostaglandin stimulus GO:0071379 3 0.012
circadian rhythm GO:0007623 19 0.011
regulation of cell projection organization GO:0031344 44 0.011
syncytium formation by plasma membrane fusion GO:0000768 12 0.011
organic substance transport GO:0071702 58 0.011
positive regulation of cell division GO:0051781 2 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
response to osmotic stress GO:0006970 11 0.011
muscle tissue development GO:0060537 110 0.011
skeletal system development GO:0001501 181 0.011
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
response to carbohydrate GO:0009743 3 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
morphogenesis of embryonic epithelium GO:0016331 30 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of bmp signaling pathway GO:0030514 13 0.011
protein phosphorylation GO:0006468 47 0.011
organic substance catabolic process GO:1901575 28 0.011
cation transmembrane transport GO:0098655 65 0.011
locomotory behavior GO:0007626 34 0.011
regulation of oocyte development GO:0060281 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
cellular catabolic process GO:0044248 27 0.011
response to other organism GO:0051707 97 0.010
post golgi vesicle mediated transport GO:0006892 1 0.010
bleb assembly GO:0032060 1 0.010
protein targeting to nucleus GO:0044744 3 0.010
macromolecule catabolic process GO:0009057 15 0.010
regulation of chondrocyte differentiation GO:0032330 1 0.010
positive regulation of transcription dna templated GO:0045893 57 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.010
glucose homeostasis GO:0042593 1 0.010
forebrain development GO:0030900 96 0.010
cellular response to oxygen levels GO:0071453 1 0.010

sepp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.146
inherited metabolic disorder DOID:655 0 0.146
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
lipid metabolism disorder DOID:3146 0 0.015