|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.446
|
Worm |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.410
|
Worm |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.379
|
Worm |
|
|
larval development
|
GO:0002164 |
2 |
0.333
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.325
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.321
|
Worm Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.307
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.299
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.295
|
Worm |
|
|
growth
|
GO:0040007 |
174 |
0.270
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.253
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.248
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.224
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.221
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.218
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.208
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.198
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.197
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.196
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.193
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.188
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.184
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.178
|
|
|
|
aging
|
GO:0007568 |
2 |
0.178
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.170
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.168
|
Fly |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.154
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.153
|
|
|
|
defense response to other organism
|
GO:0098542 |
33 |
0.152
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.151
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.149
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.148
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.146
|
|
|
|
muscle fiber development
|
GO:0048747 |
52 |
0.144
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.141
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.136
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.132
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.131
|
|
|
|
system process
|
GO:0003008 |
185 |
0.131
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.131
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.129
|
Worm |
|
|
spermatid development
|
GO:0007286 |
2 |
0.128
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.127
|
Fly |
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.126
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.126
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.122
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.119
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.118
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.117
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.116
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.116
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.115
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.115
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.114
|
Worm |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.112
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.109
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
4 |
0.108
|
Fly |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.108
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.106
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.105
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.104
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
2 |
0.102
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.102
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.100
|
Fly |
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.099
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.099
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.099
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.099
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.095
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
3 |
0.095
|
Fly |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.094
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.093
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.092
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.091
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.090
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.090
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.088
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.085
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.084
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.084
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.084
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.083
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.082
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.082
|
|
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.082
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.081
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.081
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.080
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.080
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.080
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.079
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.079
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
1 |
0.079
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.079
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.078
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.078
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.077
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.077
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.077
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.077
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.077
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.077
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.076
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.076
|
|
|
|
detection of external stimulus
|
GO:0009581 |
24 |
0.075
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.074
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
13 |
0.074
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.072
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.071
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.071
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.071
|
|
|
|
response to bacterium
|
GO:0009617 |
58 |
0.070
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.070
|
|
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.069
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
3 |
0.069
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
2 |
0.068
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.068
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.067
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.067
|
|
|
|
axis specification
|
GO:0009798 |
43 |
0.067
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.066
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.066
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.066
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.065
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.065
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.063
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.063
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.063
|
|
|
|
fertilization
|
GO:0009566 |
3 |
0.063
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.062
|
|
|
|
head development
|
GO:0060322 |
303 |
0.062
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.060
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.060
|
|
|
|
actin filament polymerization
|
GO:0030041 |
2 |
0.060
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.060
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.060
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.059
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.059
|
Fly |
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.059
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.058
|
|
|
|
stem cell division
|
GO:0017145 |
1 |
0.058
|
|
|
|
protein complex localization
|
GO:0031503 |
1 |
0.057
|
|
|
|
spermatid differentiation
|
GO:0048515 |
2 |
0.057
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.056
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.056
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.056
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.056
|
Worm |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.055
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.055
|
Worm |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.055
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.054
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.054
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.054
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.054
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.053
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.053
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
2 |
0.053
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.052
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.052
|
Fly |
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.052
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.052
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.052
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.052
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.052
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.052
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.052
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.052
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
3 |
0.051
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.051
|
|
|
|
gliogenesis
|
GO:0042063 |
45 |
0.051
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.050
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.049
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.049
|
|
|
|
sensory perception of touch
|
GO:0050975 |
2 |
0.049
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.049
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.049
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.049
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.049
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.049
|
Fly |
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.048
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.048
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.048
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.048
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.048
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.048
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.047
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.047
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
1 |
0.047
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.046
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.046
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.046
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.046
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.046
|
|
|
|
protein polymerization
|
GO:0051258 |
4 |
0.045
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.045
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.044
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.044
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.044
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.044
|
Worm |
|
|
rna polyadenylation
|
GO:0043631 |
2 |
0.044
|
|
|
|
death
|
GO:0016265 |
121 |
0.043
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
32 |
0.043
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.043
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.043
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.043
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.043
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.042
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.042
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.042
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
85 |
0.042
|
|
|
|
secondary metabolic process
|
GO:0019748 |
3 |
0.042
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.042
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.042
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.041
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
3 |
0.041
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.041
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.041
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.041
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.040
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
2 |
0.040
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
3 |
0.040
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.040
|
Worm |
|
|
muscle structure development
|
GO:0061061 |
196 |
0.040
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.040
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.040
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.040
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.039
|
|
|
|
membrane invagination
|
GO:0010324 |
1 |
0.039
|
|
|
|
oocyte development
|
GO:0048599 |
14 |
0.039
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.039
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.039
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.039
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.039
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.038
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.038
|
|
|
|
somatic muscle development
|
GO:0007525 |
4 |
0.038
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.038
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.037
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.037
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.037
|
|
|
|
defense response to bacterium
|
GO:0042742 |
22 |
0.037
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.036
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.036
|
|
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.036
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.036
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.036
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
1 |
0.036
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.036
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
23 |
0.036
|
|
|
|
membrane fusion
|
GO:0061025 |
2 |
0.036
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.036
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.036
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.035
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.034
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.034
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.034
|
|
|
|
cytoplasm organization
|
GO:0007028 |
4 |
0.034
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.034
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.034
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.033
|
|
|
|
rna 3 end processing
|
GO:0031123 |
2 |
0.033
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
1 |
0.033
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.033
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.033
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.033
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.033
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.033
|
|
|
|
germ cell development
|
GO:0007281 |
22 |
0.033
|
|
|
|
asymmetric protein localization
|
GO:0008105 |
6 |
0.033
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.033
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.033
|
|
|
|
oocyte construction
|
GO:0007308 |
5 |
0.033
|
Fly |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.033
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.033
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.033
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.032
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.032
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
2 |
0.032
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.032
|
Worm |
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
4 |
0.032
|
Fly |
|
|
detection of stimulus
|
GO:0051606 |
29 |
0.032
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.031
|
|
|
|
dicarboxylic acid transport
|
GO:0006835 |
1 |
0.031
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.031
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
2 |
0.031
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
2 |
0.031
|
|
|
|
cellular extravasation
|
GO:0045123 |
1 |
0.031
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.031
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.031
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
6 |
0.030
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
30 |
0.030
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.030
|
Fly |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.030
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.030
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.030
|
|
|
|
translational initiation
|
GO:0006413 |
3 |
0.030
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.030
|
|
|
|
spindle assembly
|
GO:0051225 |
2 |
0.030
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.030
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.030
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.030
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.030
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.030
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
27 |
0.029
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
1 |
0.029
|
|
|
|
mrna 3 end processing
|
GO:0031124 |
2 |
0.029
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.029
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.029
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.029
|
Worm |
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.029
|
Fly |
|
|
peptidyl threonine modification
|
GO:0018210 |
1 |
0.029
|
|
|
|
regulation of growth
|
GO:0040008 |
42 |
0.029
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
20 |
0.029
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.029
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.028
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.028
|
Fly |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.028
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.028
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
3 |
0.028
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.028
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.028
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.027
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
47 |
0.027
|
|
|
|
organelle fission
|
GO:0048285 |
23 |
0.027
|
Worm |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.027
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.027
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
2 |
0.027
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.027
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
1 |
0.027
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.027
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.027
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.026
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.026
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
1 |
0.026
|
Fly |
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.026
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.026
|
Worm |
|
|
female meiotic division
|
GO:0007143 |
2 |
0.026
|
|
|
|
cellular catabolic process
|
GO:0044248 |
27 |
0.026
|
|
|
|
nuclear transcribed mrna catabolic process nonsense mediated decay
|
GO:0000184 |
4 |
0.026
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.026
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.026
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.026
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.026
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
4 |
0.025
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.025
|
Worm Fly |
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
1 |
0.025
|
|
|
|
protein secretion
|
GO:0009306 |
1 |
0.025
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
33 |
0.025
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
21 |
0.025
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.024
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.024
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
1 |
0.024
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.024
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
2 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.024
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.024
|
|
|
|
proepicardium development
|
GO:0003342 |
4 |
0.024
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.024
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.024
|
|
|
|
locomotor rhythm
|
GO:0045475 |
3 |
0.024
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
8 |
0.023
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.023
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.023
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.023
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.023
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
15 |
0.023
|
|
|
|
oocyte maturation
|
GO:0001556 |
4 |
0.023
|
|
|
|
regulation of axon extension
|
GO:0030516 |
24 |
0.023
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.023
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.023
|
|
|
|
cell division
|
GO:0051301 |
20 |
0.023
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.023
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
4 |
0.023
|
|
|
|
glial cell proliferation
|
GO:0014009 |
4 |
0.023
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.023
|
|
|
|
myotube differentiation
|
GO:0014902 |
45 |
0.023
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.022
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
2 |
0.022
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.022
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
35 |
0.022
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.022
|
Fly |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.022
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.022
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
2 |
0.022
|
|
|
|
specification of axis polarity
|
GO:0065001 |
4 |
0.022
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
15 |
0.022
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.022
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.022
|
|
|
|
immune response
|
GO:0006955 |
28 |
0.022
|
|
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
4 |
0.022
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.022
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.022
|
|
|
|
protein acylation
|
GO:0043543 |
3 |
0.021
|
|
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.021
|
Fly |
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.021
|
Fly |
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.021
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.021
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
27 |
0.021
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
28 |
0.021
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
1 |
0.021
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
1 |
0.021
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
1 |
0.021
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
29 |
0.021
|
Fly |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.021
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.021
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
24 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
14 |
0.021
|
Worm |
|
|
centrosome organization
|
GO:0051297 |
1 |
0.021
|
|
|
|
sleep
|
GO:0030431 |
1 |
0.021
|
|
|
|
pronuclear migration
|
GO:0035046 |
1 |
0.020
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.020
|
|
|
|
atp catabolic process
|
GO:0006200 |
4 |
0.020
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.020
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.020
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.020
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.020
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
36 |
0.020
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.020
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.020
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
3 |
0.020
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.020
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
4 |
0.020
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.020
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.020
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
4 |
0.020
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.020
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.020
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.020
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
4 |
0.020
|
|
|
|
nucleus localization
|
GO:0051647 |
8 |
0.020
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
1 |
0.020
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.020
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.020
|
|
|
|
developmental maturation
|
GO:0021700 |
34 |
0.019
|
Fly |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.019
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.019
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
2 |
0.019
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.019
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.019
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
4 |
0.019
|
|
|
|
oxidative phosphorylation
|
GO:0006119 |
1 |
0.019
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
78 |
0.019
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.019
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
1 |
0.019
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
32 |
0.019
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.019
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
3 |
0.019
|
|
|
|
regulation of establishment or maintenance of cell polarity
|
GO:0032878 |
2 |
0.019
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
3 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.019
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
1 |
0.019
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
1 |
0.018
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
2 |
0.018
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.018
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
3 |
0.018
|
|
|
|
peptide metabolic process
|
GO:0006518 |
1 |
0.018
|
|
|
|
gene silencing
|
GO:0016458 |
4 |
0.018
|
Worm |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
2 |
0.018
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.018
|
|
|
|
regulation of mitotic cell cycle embryonic
|
GO:0009794 |
2 |
0.018
|
|
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.018
|
|
|
|
mapk cascade
|
GO:0000165 |
18 |
0.018
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.018
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
24 |
0.018
|
Fly |
|
|
regulation of wound healing
|
GO:0061041 |
2 |
0.018
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.018
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
4 |
0.017
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
4 |
0.017
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.017
|
|
|
|
gamete generation
|
GO:0007276 |
33 |
0.017
|
|
|
|
regulation of heart growth
|
GO:0060420 |
2 |
0.017
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
7 |
0.017
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.017
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.017
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.017
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
29 |
0.017
|
|
|
|
regulation of mrna catabolic process
|
GO:0061013 |
3 |
0.017
|
|
|
|
p38mapk cascade
|
GO:0038066 |
1 |
0.017
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
3 |
0.017
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
3 |
0.017
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.017
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.017
|
|
|
|
heart formation
|
GO:0060914 |
13 |
0.017
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.017
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.017
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.017
|
|
|
|
phototransduction
|
GO:0007602 |
2 |
0.017
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.017
|
|
|
|
innate immune response
|
GO:0045087 |
13 |
0.017
|
|
|
|
mrna metabolic process
|
GO:0016071 |
20 |
0.017
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.017
|
|
