Danio rerio

42 known processes

appb

amyloid beta (A4) precursor protein b

(Aliases: zgc:92771,wu:fc43a03)

appb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of developmental process GO:0050793 247 0.713
Mouse Worm
negative regulation of biological process GO:0048519 304 0.622
Human Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.575
Mouse
regulation of multicellular organismal process GO:0051239 277 0.546
Mouse Worm
negative regulation of cellular process GO:0048523 283 0.516
Human Mouse Fly
response to external stimulus GO:0009605 264 0.510
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.500
Mouse
regulation of metabolic process GO:0019222 359 0.463
Human Mouse
positive regulation of cellular process GO:0048522 201 0.444
Mouse
generation of neurons GO:0048699 385 0.420
brain development GO:0007420 293 0.412
Mouse
regulation of biological quality GO:0065008 263 0.406
Mouse
cell substrate adhesion GO:0031589 4 0.382
signal transduction GO:0007165 455 0.370
Mouse
vasculature development GO:0001944 278 0.351
response to stress GO:0006950 263 0.337
Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.328
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.310
Mouse
larval development GO:0002164 2 0.308
Worm
blood vessel development GO:0001568 246 0.297
cell surface receptor signaling pathway GO:0007166 325 0.297
Mouse
single organism metabolic process GO:0044710 217 0.270
Mouse
response to chemical GO:0042221 320 0.268
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.262
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.256
Mouse
positive regulation of signal transduction GO:0009967 56 0.255
muscle structure development GO:0061061 196 0.245
angiogenesis GO:0001525 158 0.241
aging GO:0007568 2 0.239
embryonic organ development GO:0048568 381 0.237
regulation of cell development GO:0060284 100 0.235
Mouse
regulation of catalytic activity GO:0050790 55 0.232
Human Mouse
positive regulation of signaling GO:0023056 56 0.231
central nervous system development GO:0007417 387 0.230
organic cyclic compound metabolic process GO:1901360 301 0.226
Mouse
regulation of response to stimulus GO:0048583 269 0.223
Mouse
regulation of primary metabolic process GO:0080090 311 0.222
Human Mouse
hepaticobiliary system development GO:0061008 98 0.220
cellular response to chemical stimulus GO:0070887 157 0.219
heart development GO:0007507 313 0.218
positive regulation of biological process GO:0048518 253 0.218
Mouse Worm
response to abiotic stimulus GO:0009628 122 0.211
Mouse
transcription dna templated GO:0006351 181 0.204
Mouse
regulation of cell death GO:0010941 103 0.204
Fly
blood vessel morphogenesis GO:0048514 216 0.201
regulation of nervous system development GO:0051960 90 0.195
Mouse
regulation of hydrolase activity GO:0051336 28 0.192
Human
regulation of cell shape GO:0008360 1 0.191
rna biosynthetic process GO:0032774 181 0.178
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.176
Mouse
regulation of signal transduction GO:0009966 225 0.173
Mouse
negative regulation of cell communication GO:0010648 96 0.161
organic substance biosynthetic process GO:1901576 289 0.161
Mouse
small molecule metabolic process GO:0044281 77 0.159
Mouse
regulation of cell differentiation GO:0045595 142 0.158
Mouse
organophosphate metabolic process GO:0019637 37 0.157
regulation of neurogenesis GO:0050767 87 0.153
Mouse
muscle organ development GO:0007517 101 0.147
regulation of cell communication GO:0010646 232 0.144
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.139
Mouse
phosphorus metabolic process GO:0006793 109 0.133
Mouse
nitrogen compound metabolic process GO:0006807 319 0.132
Mouse
positive regulation of molecular function GO:0044093 33 0.127
head development GO:0060322 303 0.125
Mouse
cell part morphogenesis GO:0032990 246 0.125
cellular component morphogenesis GO:0032989 336 0.124
negative regulation of molecular function GO:0044092 23 0.124
Human
cellular macromolecule metabolic process GO:0044260 391 0.124
Human Mouse
regulation of molecular function GO:0065009 70 0.118
Human Mouse
tube morphogenesis GO:0035239 349 0.116
positive regulation of cell communication GO:0010647 56 0.116
phagocytosis GO:0006909 3 0.115
regulation of cellular component organization GO:0051128 86 0.114
neuron differentiation GO:0030182 353 0.113
regulation of programmed cell death GO:0043067 101 0.113
positive regulation of metabolic process GO:0009893 108 0.112
Mouse
single organism transport GO:0044765 206 0.112
Mouse
positive regulation of cell matrix adhesion GO:0001954 1 0.112
phagocytosis engulfment GO:0006911 1 0.109
localization of cell GO:0051674 244 0.108
cell proliferation GO:0008283 80 0.108
nucleic acid metabolic process GO:0090304 244 0.108
Mouse
negative regulation of cell death GO:0060548 60 0.105
Fly
small gtpase mediated signal transduction GO:0007264 8 0.105
regulation of cellular component movement GO:0051270 55 0.104
heterocycle metabolic process GO:0046483 290 0.103
Mouse
glial cell proliferation GO:0014009 4 0.103
cellular carbohydrate metabolic process GO:0044262 4 0.102
cranial nerve development GO:0021545 42 0.101
regulation of cell matrix adhesion GO:0001952 1 0.100
cognition GO:0050890 1 0.100
Mouse Fly
cellular response to organic substance GO:0071310 105 0.100
response to organic substance GO:0010033 153 0.099
heart morphogenesis GO:0003007 156 0.098
developmental growth GO:0048589 166 0.097
Mouse Worm
retina development in camera type eye GO:0060041 146 0.096
growth GO:0040007 174 0.095
Mouse Worm
ameboidal type cell migration GO:0001667 143 0.094
regulation of sodium ion transport GO:0002028 2 0.093
intracellular signal transduction GO:0035556 85 0.093
sprouting angiogenesis GO:0002040 53 0.092
regulation of neuron differentiation GO:0045664 56 0.086
Mouse
morphogenesis of an epithelium GO:0002009 333 0.085
tissue migration GO:0090130 37 0.082
transmembrane transport GO:0055085 120 0.082
eye development GO:0001654 277 0.081
programmed cell death GO:0012501 119 0.080
Human Mouse
membrane organization GO:0061024 21 0.079
cell fate commitment GO:0045165 99 0.078
inorganic cation transmembrane transport GO:0098662 50 0.076
inner ear development GO:0048839 126 0.075
positive regulation of apoptotic signaling pathway GO:2001235 1 0.075
apoptotic process GO:0006915 116 0.074
Human Mouse
cell projection organization GO:0030030 284 0.072
negative regulation of multicellular organismal process GO:0051241 69 0.070
Mouse
cell death GO:0008219 121 0.069
Human Mouse Fly
negative regulation of blood circulation GO:1903523 2 0.069
taxis GO:0042330 109 0.069
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.069
response to radiation GO:0009314 51 0.067
Mouse
purine ribonucleotide metabolic process GO:0009150 27 0.067
outflow tract morphogenesis GO:0003151 1 0.066
regulation of cellular amine metabolic process GO:0033238 0 0.066
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.066
ion transmembrane transport GO:0034220 91 0.065
regulation of phosphorus metabolic process GO:0051174 43 0.065
Mouse
axon development GO:0061564 166 0.064
glucose homeostasis GO:0042593 1 0.064
liver development GO:0001889 96 0.064
specification of symmetry GO:0009799 204 0.063
ear development GO:0043583 127 0.062
regulation of camp metabolic process GO:0030814 9 0.061
positive regulation of response to stimulus GO:0048584 80 0.061
cellular amino acid metabolic process GO:0006520 7 0.061
cell migration GO:0016477 237 0.060
neuron death GO:0070997 21 0.059
Human Mouse Fly
neural nucleus development GO:0048857 15 0.058
response to biotic stimulus GO:0009607 97 0.058
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.057
cell motility GO:0048870 244 0.056
regulation of signaling GO:0023051 235 0.056
Mouse
regulation of multicellular organism growth GO:0040014 4 0.056
Mouse Worm
regulation of response to external stimulus GO:0032101 31 0.056
protein localization to plasma membrane GO:0072659 1 0.055
axis specification GO:0009798 43 0.055
neuroblast proliferation GO:0007405 2 0.054
skeletal muscle fiber development GO:0048741 35 0.054
response to other organism GO:0051707 97 0.054
positive regulation of cell substrate adhesion GO:0010811 1 0.053
response to growth factor GO:0070848 39 0.053
death GO:0016265 121 0.052
Human Mouse Fly
regulation of ion transmembrane transporter activity GO:0032412 2 0.052
regulation of macromolecule metabolic process GO:0060255 317 0.051
Human Mouse
cellular response to growth factor stimulus GO:0071363 39 0.051
cellular amine metabolic process GO:0044106 2 0.051
single organism localization GO:1902578 225 0.050
Mouse
regeneration GO:0031099 91 0.050
olfactory placode morphogenesis GO:0071699 7 0.049
aromatic compound biosynthetic process GO:0019438 217 0.049
Mouse
gene expression GO:0010467 252 0.049
Human Mouse
neuron projection development GO:0031175 180 0.049
membrane invagination GO:0010324 1 0.048
cranial nerve morphogenesis GO:0021602 15 0.047
regulation of circadian rhythm GO:0042752 4 0.047
ion transport GO:0006811 114 0.047
regulation of cellular protein metabolic process GO:0032268 52 0.047
Human Mouse
sensory organ development GO:0007423 393 0.047
positive regulation of protein kinase b signaling GO:0051897 1 0.046
peptidyl serine modification GO:0018209 2 0.046
erk1 and erk2 cascade GO:0070371 4 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
regulation of cellular response to growth factor stimulus GO:0090287 35 0.045
gland development GO:0048732 143 0.045
muscle cell differentiation GO:0042692 139 0.044
neuron projection guidance GO:0097485 86 0.044
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.044
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.044
neuron development GO:0048666 262 0.044
myeloid cell homeostasis GO:0002262 56 0.043
regulation of protein transport GO:0051223 3 0.043
regulation of dendrite development GO:0050773 3 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
Mouse
inorganic ion transmembrane transport GO:0098660 57 0.042
enzyme linked receptor protein signaling pathway GO:0007167 106 0.042
Mouse
otic vesicle development GO:0071599 42 0.042
organonitrogen compound metabolic process GO:1901564 74 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.041
negative regulation of catalytic activity GO:0043086 21 0.041
Human
regulation of gene expression GO:0010468 265 0.041
Human Mouse
negative regulation of developmental process GO:0051093 65 0.041
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.040
Mouse
multicellular organism growth GO:0035264 4 0.040
Mouse Worm
fatty acid transport GO:0015908 1 0.039
regulation of reproductive process GO:2000241 4 0.039
establishment of protein localization to plasma membrane GO:0090002 1 0.039
cyclic nucleotide metabolic process GO:0009187 18 0.038
transport GO:0006810 220 0.038
Mouse
regulation of blood circulation GO:1903522 32 0.038
amine metabolic process GO:0009308 2 0.038
embryonic heart tube development GO:0035050 133 0.038
regulation of oocyte development GO:0060281 3 0.037
embryonic hemopoiesis GO:0035162 53 0.037
olfactory lobe development GO:0021988 4 0.037
negative regulation of metabolic process GO:0009892 86 0.037
Human
energy reserve metabolic process GO:0006112 2 0.037
response to wounding GO:0009611 116 0.037
Fly
regulation of receptor activity GO:0010469 2 0.036
Mouse
cell matrix adhesion GO:0007160 4 0.036
adult behavior GO:0030534 2 0.035
Mouse
purine containing compound metabolic process GO:0072521 29 0.035
purine nucleotide metabolic process GO:0006163 27 0.035
regulation of nucleocytoplasmic transport GO:0046822 2 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.033
Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.033
cytoskeleton organization GO:0007010 96 0.033
epithelial tube morphogenesis GO:0060562 148 0.032
neuron projection regeneration GO:0031102 16 0.032
positive regulation of hydrolase activity GO:0051345 13 0.032
regulation of cardiac muscle contraction GO:0055117 2 0.032
rna metabolic process GO:0016070 219 0.032
Mouse
system process GO:0003008 185 0.032
Mouse Fly
regulation of intracellular protein transport GO:0033157 3 0.032
modulation by virus of host morphology or physiology GO:0019048 1 0.032
synaptic target recognition GO:0008039 1 0.032
nucleotide metabolic process GO:0009117 28 0.031
regulation of cell morphogenesis GO:0022604 42 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
negative regulation of gene expression GO:0010629 65 0.031
Human
cell migration involved in heart formation GO:0060974 10 0.030
anterior posterior axis specification GO:0009948 20 0.030
negative regulation of cellular catabolic process GO:0031330 3 0.030
cellular component assembly GO:0022607 170 0.030
Mouse
regulation of peptidase activity GO:0052547 23 0.029
Human
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.029
regulation of intracellular signal transduction GO:1902531 57 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
Mouse
regulation of autophagy GO:0010506 3 0.029
extracellular matrix organization GO:0030198 27 0.028
Mouse
carbohydrate homeostasis GO:0033500 1 0.028
response to carbohydrate GO:0009743 3 0.028
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.028
hemopoiesis GO:0030097 183 0.028
regulation of neuron projection development GO:0010975 40 0.028
regulation of biosynthetic process GO:0009889 250 0.027
Mouse
positive regulation of developmental process GO:0051094 50 0.027
Worm
neurological system process GO:0050877 62 0.027
Mouse Fly
mitotic cell cycle process GO:1903047 48 0.027
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.026
macromolecule modification GO:0043412 111 0.026
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
establishment of localization GO:0051234 244 0.026
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.026
locomotion GO:0040011 313 0.026
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.026
cellular biosynthetic process GO:0044249 286 0.026
Mouse
regulation of establishment of protein localization GO:0070201 4 0.026
positive regulation of catabolic process GO:0009896 4 0.026
meiotic nuclear division GO:0007126 4 0.026
regulation of cell projection organization GO:0031344 44 0.025
regulation of cell substrate adhesion GO:0010810 1 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
macromolecule localization GO:0033036 54 0.025
establishment of synaptic vesicle localization GO:0097480 1 0.025
nucleus localization GO:0051647 8 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
Mouse
cellular component movement GO:0006928 335 0.025
Mouse
phosphorylation GO:0016310 69 0.025
Mouse
organelle organization GO:0006996 227 0.025
olfactory bulb development GO:0021772 4 0.025
regionalization GO:0003002 274 0.024
muscle fiber development GO:0048747 52 0.024
protein stabilization GO:0050821 2 0.024
single organism biosynthetic process GO:0044711 71 0.024
negative regulation of cell differentiation GO:0045596 46 0.024
Mouse
negative regulation of response to stimulus GO:0048585 104 0.024
negative regulation of chemotaxis GO:0050922 4 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
cellular response to hypoxia GO:0071456 1 0.024
oxoacid metabolic process GO:0043436 31 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
response to external biotic stimulus GO:0043207 97 0.024
action potential GO:0001508 19 0.024
single organism organelle organization GO:1902589 199 0.024
interaction with host GO:0051701 4 0.024
axon regeneration GO:0031103 14 0.024
regulation of heart contraction GO:0008016 32 0.024
response to glucose GO:0009749 3 0.023
ras protein signal transduction GO:0007265 7 0.023
regulation of metal ion transport GO:0010959 4 0.023
protein modification process GO:0036211 100 0.023
Mouse
sodium ion transport GO:0006814 24 0.023
camera type eye development GO:0043010 222 0.023
response to temperature stimulus GO:0009266 15 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.023
cellular ketone metabolic process GO:0042180 11 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
positive regulation of catalytic activity GO:0043085 25 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
regulation of cell migration GO:0030334 40 0.022
negative regulation of catabolic process GO:0009895 3 0.022
carbohydrate biosynthetic process GO:0016051 1 0.022
regulation of calcium ion transport GO:0051924 2 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
regulation of cell motility GO:2000145 46 0.022
single organism behavior GO:0044708 24 0.022
Mouse Fly
regulation of chemotaxis GO:0050920 18 0.022
carbohydrate metabolic process GO:0005975 12 0.022
posterior lateral line development GO:0048916 38 0.021
cellular protein metabolic process GO:0044267 129 0.021
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
Mouse
regulation of locomotion GO:0040012 55 0.021
positive regulation of lipase activity GO:0060193 1 0.021
cellular component biogenesis GO:0044085 178 0.021
Mouse
regulation of protein targeting GO:1903533 2 0.021
protein metabolic process GO:0019538 183 0.021
Human Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
striated muscle cell differentiation GO:0051146 129 0.021
membrane repolarization GO:0086009 2 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
regulation of localization GO:0032879 104 0.021
rna 3 end processing GO:0031123 2 0.020
Mouse
negative chemotaxis GO:0050919 1 0.020
regulation of transporter activity GO:0032409 2 0.020
chemotaxis GO:0006935 104 0.020
Mouse
semicircular canal development GO:0060872 24 0.020
convergent extension GO:0060026 118 0.020
response to hexose GO:0009746 3 0.020
cell migration involved in heart development GO:0060973 22 0.020
cellular response to stress GO:0033554 62 0.020
single organism carbohydrate metabolic process GO:0044723 12 0.020
biomineral tissue development GO:0031214 13 0.020
positive regulation of multicellular organismal process GO:0051240 52 0.020
Worm
cellular response to external stimulus GO:0071496 2 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
regulation of mapk cascade GO:0043408 14 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
Mouse
biosynthetic process GO:0009058 294 0.019
Mouse
positive regulation of cell adhesion GO:0045785 1 0.019
hindbrain development GO:0030902 91 0.019
regulation of nucleotide metabolic process GO:0006140 17 0.019
negative regulation of heart contraction GO:0045822 2 0.019
exocytosis GO:0006887 1 0.019
actin cytoskeleton organization GO:0030036 63 0.019
negative regulation of protein transport GO:0051224 3 0.019
regulation of transcription dna templated GO:0006355 213 0.019
Mouse
heart looping GO:0001947 94 0.019
metal ion transport GO:0030001 58 0.019
regulation of protein kinase b signaling GO:0051896 8 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
meiotic cell cycle process GO:1903046 3 0.018
organelle localization GO:0051640 49 0.018
negative regulation of cell migration GO:0030336 17 0.018
single organismal cell cell adhesion GO:0016337 29 0.018
establishment of organelle localization GO:0051656 45 0.018
zymogen activation GO:0031638 3 0.018
response to metal ion GO:0010038 34 0.018
cardiac cell fate commitment GO:0060911 1 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
anterior posterior pattern specification GO:0009952 152 0.017
entrainment of circadian clock GO:0009649 2 0.017
response to decreased oxygen levels GO:0036293 25 0.017
mrna 3 end processing GO:0031124 2 0.017
Mouse
defense response GO:0006952 47 0.017
regulation of protein modification process GO:0031399 29 0.017
Mouse
sensory organ morphogenesis GO:0090596 200 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
dendrite guidance GO:0070983 0 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
Mouse
divalent inorganic cation homeostasis GO:0072507 22 0.017
Mouse
ectodermal placode development GO:0071696 37 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
retinal ganglion cell axon guidance GO:0031290 35 0.017
muscle tissue development GO:0060537 110 0.017
negative regulation of sequestering of calcium ion GO:0051283 4 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
Mouse
regulation of cell activation GO:0050865 1 0.017
regulation of cell maturation GO:1903429 1 0.017
response to alkaloid GO:0043279 2 0.017
response to monosaccharide GO:0034284 3 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
stem cell proliferation GO:0072089 4 0.017
epithelial cell migration GO:0010631 25 0.017
digestive system development GO:0055123 289 0.016
positive regulation of gliogenesis GO:0014015 2 0.016
cell substrate junction assembly GO:0007044 2 0.016
stem cell division GO:0017145 1 0.016
blood circulation GO:0008015 87 0.016
organic acid metabolic process GO:0006082 31 0.016
positive regulation of biosynthetic process GO:0009891 68 0.016
Mouse
macromolecule biosynthetic process GO:0009059 227 0.016
Mouse
negative regulation of signaling GO:0023057 96 0.016
detection of stimulus GO:0051606 29 0.016
neuromuscular process controlling balance GO:0050885 3 0.016
Mouse
regulation of behavior GO:0050795 24 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
negative regulation of cell motility GO:2000146 17 0.016
olfactory placode development GO:0071698 12 0.016
cellular homeostasis GO:0019725 26 0.016
Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.016
neural tube formation GO:0001841 16 0.015
erythrocyte homeostasis GO:0034101 55 0.015
negative regulation of secretion by cell GO:1903531 2 0.015
protein import GO:0017038 3 0.015
ear morphogenesis GO:0042471 64 0.015
negative regulation of protein processing GO:0010955 10 0.015
Human
negative regulation of intracellular protein transport GO:0090317 3 0.015
sequestering of metal ion GO:0051238 3 0.015
negative regulation of cellular component movement GO:0051271 18 0.015
developmental process involved in reproduction GO:0003006 27 0.015
regulation of bone mineralization GO:0030500 2 0.015
skeletal muscle organ development GO:0060538 78 0.015
adherens junction maintenance GO:0034334 2 0.014
regulation of ion transmembrane transport GO:0034765 18 0.014
epithelium migration GO:0090132 25 0.014
regulation of cytokine production GO:0001817 3 0.014
organism emergence from protective structure GO:0071684 4 0.014
primitive erythrocyte differentiation GO:0060319 5 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
regulation of protein maturation GO:1903317 10 0.014
Human
extracellular structure organization GO:0043062 27 0.014
Mouse
determination of bilateral symmetry GO:0009855 204 0.014
regulation of protein phosphorylation GO:0001932 18 0.014
Mouse
nerve development GO:0021675 45 0.014
negative regulation of cellular protein metabolic process GO:0032269 16 0.014
Human
ribonucleotide metabolic process GO:0009259 27 0.014
cardioblast migration GO:0003260 7 0.014
regulation of purine nucleotide metabolic process GO:1900542 17 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.014
neural tube development GO:0021915 62 0.014
synaptic vesicle transport GO:0048489 1 0.014
regulation of gtpase activity GO:0043087 2 0.013
maintenance of location GO:0051235 4 0.013
neuron projection morphogenesis GO:0048812 161 0.013
intracellular receptor signaling pathway GO:0030522 30 0.013
regulation of rac protein signal transduction GO:0035020 1 0.013
negative regulation of endopeptidase activity GO:0010951 10 0.013
Human
fertilization GO:0009566 3 0.013
regulation of sodium ion transmembrane transport GO:1902305 1 0.013
forebrain development GO:0030900 96 0.013
Mouse
positive regulation of cell cycle GO:0045787 3 0.013
Mouse
negative regulation of signal transduction GO:0009968 94 0.013
homeostatic process GO:0042592 142 0.013
Mouse
monovalent inorganic cation transport GO:0015672 42 0.013
single organism cellular localization GO:1902580 46 0.013
regulation of growth rate GO:0040009 1 0.013
germ line stem cell maintenance GO:0030718 2 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
positive regulation of cell division GO:0051781 2 0.013
cell junction organization GO:0034330 11 0.013
actin filament based process GO:0030029 64 0.013
asymmetric protein localization GO:0008105 6 0.013
striated muscle tissue development GO:0014706 110 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of extent of cell growth GO:0061387 29 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
protein localization GO:0008104 40 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
Mouse
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
negative regulation of locomotion GO:0040013 18 0.012
regulation of cell cycle GO:0051726 52 0.012
Mouse
cell growth GO:0016049 57 0.012
Mouse
regulation of gtp catabolic process GO:0033124 2 0.012
peripheral nervous system neuron axonogenesis GO:0048936 13 0.012
stem cell maintenance GO:0019827 4 0.012
sequestering of calcium ion GO:0051208 3 0.012
positive regulation of cellular protein metabolic process GO:0032270 22 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
Mouse
adherens junction organization GO:0034332 4 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
synapse organization GO:0050808 21 0.012
Mouse Fly
endocytosis GO:0006897 16 0.012
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.012
Mouse
positive regulation of intracellular signal transduction GO:1902533 15 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of protein complex assembly GO:0043254 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
single organism membrane organization GO:0044802 20 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Mouse

appb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.026
bone disease DOID:0080001 0 0.026
disease of anatomical entity DOID:7 0 0.026
Human
dysostosis DOID:1934 0 0.026
musculoskeletal system disease DOID:17 0 0.026
connective tissue disease DOID:65 0 0.026
synostosis DOID:11971 0 0.026
disease of metabolism DOID:0014667 0 0.019
Human
amyloidosis DOID:9120 0 0.019
Human
acquired metabolic disease DOID:0060158 0 0.019
Human