|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.826
|
Mouse |
|
|
organelle organization
|
GO:0006996 |
227 |
0.797
|
Human Zebrafish Mouse Worm |
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.775
|
Human Mouse Worm |
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.763
|
Zebrafish |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.734
|
|
|
|
response to oxidative stress
|
GO:0006979 |
11 |
0.712
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.684
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.683
|
Zebrafish Mouse Worm |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.636
|
Zebrafish Mouse Worm |
|
|
response to metal ion
|
GO:0010038 |
34 |
0.619
|
Zebrafish |
|
|
response to chemical
|
GO:0042221 |
320 |
0.576
|
Human Zebrafish Mouse |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.547
|
|
|
|
response to methylmercury
|
GO:0051597 |
11 |
0.546
|
Zebrafish |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
2 |
0.546
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.545
|
Zebrafish Mouse |
|
|
response to ionizing radiation
|
GO:0010212 |
6 |
0.532
|
Mouse |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.529
|
|
|
|
response to cadmium ion
|
GO:0046686 |
14 |
0.504
|
Zebrafish |
|
|
cell death in response to oxidative stress
|
GO:0036473 |
2 |
0.502
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.481
|
Worm |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.478
|
Zebrafish Mouse |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.462
|
Zebrafish Mouse |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.461
|
Mouse |
|
|
apoptotic process
|
GO:0006915 |
116 |
0.461
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.458
|
Human Zebrafish Mouse |
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.454
|
Worm |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.445
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.434
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.424
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.423
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.422
|
Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.395
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.376
|
Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
23 |
0.376
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.375
|
Human Zebrafish |
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.374
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
28 |
0.372
|
Zebrafish |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.370
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.366
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.365
|
Human Zebrafish Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.362
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.356
|
Worm |
|
|
transport
|
GO:0006810 |
220 |
0.355
|
Human |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.355
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.355
|
Mouse |
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.342
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.323
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
29 |
0.321
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.320
|
Human |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.310
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.308
|
Human |
|
|
organelle fission
|
GO:0048285 |
23 |
0.302
|
Zebrafish |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.302
|
Human Zebrafish Mouse |
|
|
regionalization
|
GO:0003002 |
274 |
0.300
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.291
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.289
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.286
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.280
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.272
|
Human Zebrafish Mouse Worm |
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.269
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.263
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.261
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.260
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.259
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.257
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.256
|
Human Zebrafish |
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.252
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.247
|
|
|
|
death
|
GO:0016265 |
121 |
0.247
|
|
|
|
mitochondrial transport
|
GO:0006839 |
2 |
0.246
|
Human |
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.240
|
Zebrafish |
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.237
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
2 |
0.232
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.226
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.226
|
Mouse |
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.221
|
|
|
|
head development
|
GO:0060322 |
303 |
0.220
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.220
|
Human Zebrafish |
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.218
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
1 |
0.213
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.213
|
|
|
|
organelle fusion
|
GO:0048284 |
3 |
0.209
|
Worm |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
2 |
0.206
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.203
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.199
|
Human Zebrafish |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.198
|
|
|
|
thyroid gland development
|
GO:0030878 |
12 |
0.194
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.194
|
Worm |
|
|
programmed cell death
|
GO:0012501 |
119 |
0.194
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.188
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.185
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.185
|
|
|
|
atp catabolic process
|
GO:0006200 |
4 |
0.184
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.183
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.179
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.178
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.178
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.178
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.170
|
Human Mouse |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.169
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.169
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.166
|
Worm |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.165
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
10 |
0.164
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
8 |
0.162
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.162
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
1 |
0.161
|
Human |
|
|
nuclear division
|
GO:0000280 |
23 |
0.157
|
Zebrafish |
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.156
|
Human Zebrafish Worm |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.155
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.153
|
|
|
|
aging
|
GO:0007568 |
2 |
0.150
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.148
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.146
|
Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.144
|
Mouse |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.143
|
Worm |
|
|
single organism membrane fusion
|
GO:0044801 |
2 |
0.141
|
Worm |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.140
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.138
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
20 |
0.134
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.133
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.132
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.132
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.131
|
Human |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.130
|
Mouse |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.129
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.129
|
Zebrafish |
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
1 |
0.128
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.127
|
Mouse |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.127
|
|
|
|
response to steroid hormone
|
GO:0048545 |
35 |
0.127
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.127
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.126
|
Zebrafish Mouse |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.126
|
Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.125
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
20 |
0.125
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.122
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.122
|
Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.121
|
Mouse |
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.121
|
|
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.121
|
Mouse |
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.121
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.120
|
Worm |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.117
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.117
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.116
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.116
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
2 |
0.115
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.114
|
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.114
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.114
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.113
|
Human Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.113
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.111
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.110
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.109
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.109
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.108
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.107
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.107
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
56 |
0.107
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.106
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.106
|
|
|
|
hormone transport
|
GO:0009914 |
2 |
0.106
|
|
|
|
multi organism cellular process
|
GO:0044764 |
2 |
0.106
|
Human |
|
|
regulation of heart contraction
|
GO:0008016 |
32 |
0.105
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.105
|
Worm |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.104
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.104
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
13 |
0.104
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.101
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.100
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.100
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
23 |
0.099
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.097
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.096
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.096
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.096
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
2 |
0.096
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.095
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.095
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.094
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.094
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.094
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.093
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.093
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.089
|
|
|
|
locomotor rhythm
|
GO:0045475 |
3 |
0.089
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.088
|
|
|
|
system process
|
GO:0003008 |
185 |
0.088
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.087
|
Worm |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
10 |
0.087
|
Zebrafish |
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.087
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.086
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
55 |
0.086
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.086
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.085
|
|
|
|
actin filament based movement
|
GO:0030048 |
1 |
0.085
|
|
|
|
response to vitamin
|
GO:0033273 |
3 |
0.085
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
1 |
0.084
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.083
|
Worm |
|
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.082
|
|
|
|
response to virus
|
GO:0009615 |
21 |
0.082
|
Mouse |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.082
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.082
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
27 |
0.082
|
Worm |
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.082
|
|
|
|
tissue homeostasis
|
GO:0001894 |
25 |
0.082
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.082
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.081
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.080
|
Human Zebrafish |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.080
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.079
|
Worm |
|
|
regulation of localization
|
GO:0032879 |
104 |
0.079
|
Human |
|
|
growth
|
GO:0040007 |
174 |
0.078
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.077
|
Worm |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
27 |
0.076
|
Worm |
|
|
gene expression
|
GO:0010467 |
252 |
0.076
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.076
|
|
|
|
response to cytokine
|
GO:0034097 |
7 |
0.075
|
Human |
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.075
|
Human Mouse |
|
|
protein homooligomerization
|
GO:0051260 |
3 |
0.074
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.074
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.073
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
16 |
0.073
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.073
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
4 |
0.073
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.073
|
Zebrafish Mouse Worm |
|
|
centrosome cycle
|
GO:0007098 |
1 |
0.073
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.072
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.072
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
7 |
0.072
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.072
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.071
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.071
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
23 |
0.070
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
29 |
0.070
|
Worm |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
2 |
0.070
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.069
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
21 |
0.069
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
10 |
0.069
|
Zebrafish |
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.069
|
Worm |
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.068
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.068
|
Human |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.068
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
22 |
0.067
|
|
|
|
b cell activation
|
GO:0042113 |
2 |
0.067
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.067
|
Zebrafish |
|
|
response to hydrogen peroxide
|
GO:0042542 |
3 |
0.067
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.067
|
|
|
|
biological adhesion
|
GO:0022610 |
40 |
0.066
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.066
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.066
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.065
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.064
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
1 |
0.064
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
10 |
0.064
|
Zebrafish |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
4 |
0.064
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
7 |
0.063
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.062
|
|
|
|
response to ketone
|
GO:1901654 |
1 |
0.062
|
|
|
|
endocrine system development
|
GO:0035270 |
65 |
0.062
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.062
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.062
|
|
|
|
rhythmic process
|
GO:0048511 |
21 |
0.061
|
Mouse |
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.061
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.061
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.061
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.061
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.061
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.060
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.060
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
16 |
0.060
|
|
|
|
heart contraction
|
GO:0060047 |
71 |
0.059
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.059
|
|
|
|
transmembrane transport
|
GO:0055085 |
120 |
0.058
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.058
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.058
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.058
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.058
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.058
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.056
|
Zebrafish |
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.056
|
|
|
|
regulation of dna catabolic process
|
GO:1903624 |
1 |
0.055
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.055
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.055
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
10 |
0.055
|
Zebrafish |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.055
|
|
|
|
fluid transport
|
GO:0042044 |
17 |
0.055
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.055
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.054
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.054
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.054
|
Worm |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.054
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.054
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
4 |
0.053
|
Human |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.053
|
Mouse |
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.053
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.053
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.052
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.052
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.052
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.052
|
Mouse |
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.052
|
Worm |
|
|
b cell differentiation
|
GO:0030183 |
1 |
0.051
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.051
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.050
|
Human Zebrafish |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.050
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.050
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
10 |
0.050
|
|
|
|
protein complex assembly
|
GO:0006461 |
30 |
0.050
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
32 |
0.050
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.050
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.049
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.049
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
4 |
0.049
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.049
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.049
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.048
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
5 |
0.048
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.048
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.048
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
1 |
0.048
|
Human Worm |
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.048
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
25 |
0.046
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.046
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.046
|
Human |
|
|
regulation of system process
|
GO:0044057 |
40 |
0.046
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.046
|
|
|
|
interaction with host
|
GO:0051701 |
4 |
0.046
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.045
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
4 |
0.045
|
|
|
|
urogenital system development
|
GO:0001655 |
97 |
0.045
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
13 |
0.045
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.045
|
Human Zebrafish |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
2 |
0.044
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
2 |
0.044
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.044
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.044
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.044
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.044
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.044
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.043
|
|
|
|
cation transport
|
GO:0006812 |
81 |
0.043
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.043
|
Human Zebrafish |
|
|
dna catabolic process
|
GO:0006308 |
1 |
0.043
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
2 |
0.043
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
11 |
0.043
|
Worm |
|
|
response to hexose
|
GO:0009746 |
3 |
0.042
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
2 |
0.042
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.042
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
2 |
0.042
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.042
|
Worm |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.042
|
|
|
|
response to hormone
|
GO:0009725 |
48 |
0.041
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.041
|
Zebrafish Worm |
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.041
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.040
|
Zebrafish Worm |
|
|
membrane fusion
|
GO:0061025 |
2 |
0.040
|
Worm |
|
|
kidney development
|
GO:0001822 |
92 |
0.040
|
|
|
|
negative regulation of signal transduction by p53 class mediator
|
GO:1901797 |
8 |
0.040
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
28 |
0.040
|
|
|
|
metal ion transport
|
GO:0030001 |
58 |
0.040
|
|
|
|
actin filament based process
|
GO:0030029 |
64 |
0.039
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
9 |
0.039
|
Zebrafish |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.039
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.039
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.038
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
39 |
0.038
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.038
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.038
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
4 |
0.038
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.038
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
10 |
0.037
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.037
|
|
|
|
neuron death
|
GO:0070997 |
21 |
0.037
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
152 |
0.037
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.037
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.037
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
30 |
0.037
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.037
|
Worm |
|
|
developmental growth
|
GO:0048589 |
166 |
0.036
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.036
|
Human |
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.036
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.036
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.036
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.036
|
|
|
|
p38mapk cascade
|
GO:0038066 |
1 |
0.036
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
4 |
0.035
|
Zebrafish |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.035
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.035
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.035
|
|
|
|
dna metabolic process
|
GO:0006259 |
27 |
0.034
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.034
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.034
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
32 |
0.034
|
Worm |
|
|
meiosis i
|
GO:0007127 |
1 |
0.034
|
|
|
|
negative regulation of heart contraction
|
GO:0045822 |
2 |
0.034
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
2 |
0.034
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.034
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
2 |
0.034
|
|
|
|
killing of cells of other organism
|
GO:0031640 |
1 |
0.034
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.034
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.034
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.033
|
Worm |
|
|
forebrain cell migration
|
GO:0021885 |
1 |
0.033
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.033
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.033
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
13 |
0.033
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.033
|
|
|
|
response to estrogen
|
GO:0043627 |
27 |
0.033
|
|
|
|
disruption of cells of other organism
|
GO:0044364 |
1 |
0.032
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.032
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.032
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
15 |
0.032
|
Worm |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.032
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.032
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
2 |
0.032
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.032
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
10 |
0.032
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.031
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
29 |
0.031
|
|
|
|
response to alcohol
|
GO:0097305 |
14 |
0.031
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.031
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.031
|
Worm |
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.031
|
|
|
|
cellular sodium ion homeostasis
|
GO:0006883 |
1 |
0.031
|
|
|
|
anion transport
|
GO:0006820 |
38 |
0.031
|
|
|
|
viral process
|
GO:0016032 |
1 |
0.031
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.031
|
|
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.031
|
Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.031
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
15 |
0.030
|
Worm |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.030
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.030
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.030
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.030
|
|
|
|
steroid hormone secretion
|
GO:0035929 |
1 |
0.030
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.030
|
|
|
|
heart process
|
GO:0003015 |
71 |
0.030
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.030
|
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.029
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.029
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.029
|
Worm |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.029
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.029
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
2 |
0.029
|
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
13 |
0.029
|
Zebrafish Worm |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.029
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.029
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
4 |
0.028
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.028
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.028
|
|
|
|
circadian rhythm
|
GO:0007623 |
19 |
0.028
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
91 |
0.028
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
1 |
0.028
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.028
|
|
|
|
axis specification
|
GO:0009798 |
43 |
0.028
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.028
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.027
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
6 |
0.027
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.027
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.027
|
Mouse |
|
|
cytokinesis
|
GO:0000910 |
3 |
0.027
|
Human |
|
|
negative regulation of blood circulation
|
GO:1903523 |
2 |
0.027
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
3 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
19 |
0.027
|
Mouse |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.027
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.027
|
Worm |
|
|
muscle structure development
|
GO:0061061 |
196 |
0.027
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.027
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
1 |
0.027
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.027
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.027
|
|
|
|
cellular catabolic process
|
GO:0044248 |
27 |
0.027
|
Worm |
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.027
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.027
|
|
|
|
diencephalon development
|
GO:0021536 |
58 |
0.026
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.026
|
|
|
|
response to amine
|
GO:0014075 |
1 |
0.026
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.026
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.026
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.026
|
Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
2 |
0.026
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
3 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
39 |
0.026
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.026
|
|
|
|
regulation of cell division
|
GO:0051302 |
12 |
0.026
|
Zebrafish |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.026
|
Worm |
|
|
segmentation
|
GO:0035282 |
97 |
0.025
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.025
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.025
|
|
