Danio rerio

35 known processes

ctbp2l

C-terminal binding protein 2, like

ctbp2l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.923
eye development GO:0001654 277 0.620
neuromuscular process controlling balance GO:0050885 3 0.550
inner ear development GO:0048839 126 0.333
sensory organ morphogenesis GO:0090596 200 0.316
embryonic organ development GO:0048568 381 0.313
polarized epithelial cell differentiation GO:0030859 4 0.240
response to stress GO:0006950 263 0.228
negative regulation of biological process GO:0048519 304 0.195
embryonic organ morphogenesis GO:0048562 274 0.169
establishment of epithelial cell polarity GO:0090162 2 0.166
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.166
camera type eye development GO:0043010 222 0.151
regulation of jak stat cascade GO:0046425 3 0.126
regulation of cellular response to oxidative stress GO:1900407 2 0.121
membrane fusion GO:0061025 2 0.120
regulation of response to cytokine stimulus GO:0060759 3 0.119
tube morphogenesis GO:0035239 349 0.118
angiogenesis GO:0001525 158 0.113
signal transduction GO:0007165 455 0.107
retina development in camera type eye GO:0060041 146 0.107
regulation of synapse assembly GO:0051963 3 0.105
axon development GO:0061564 166 0.104
single organism membrane fusion GO:0044801 2 0.102
regulation of synapse organization GO:0050807 3 0.091
brain development GO:0007420 293 0.091
cognition GO:0050890 1 0.088
establishment of localization GO:0051234 244 0.087
regulation of biological quality GO:0065008 263 0.087
negative regulation of response to stimulus GO:0048585 104 0.085
heart morphogenesis GO:0003007 156 0.084
negative regulation of cell communication GO:0010648 96 0.081
neuron development GO:0048666 262 0.079
neuron differentiation GO:0030182 353 0.077
immune system development GO:0002520 191 0.075
inner ear morphogenesis GO:0042472 63 0.075
eye morphogenesis GO:0048592 144 0.074
cellular component movement GO:0006928 335 0.072
regulation of multicellular organismal process GO:0051239 277 0.068
visual perception GO:0007601 17 0.067
cell migration GO:0016477 237 0.066
immune system process GO:0002376 241 0.064
generation of neurons GO:0048699 385 0.063
regulation of intracellular signal transduction GO:1902531 57 0.063
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.063
axonogenesis GO:0007409 152 0.062
neural retina development GO:0003407 49 0.061
gland development GO:0048732 143 0.059
single organism localization GO:1902578 225 0.059
energy homeostasis GO:0097009 3 0.059
photoreceptor cell differentiation GO:0046530 55 0.057
cellular amine metabolic process GO:0044106 2 0.055
embryonic cranial skeleton morphogenesis GO:0048701 90 0.054
larval development GO:0002164 2 0.052
nerve development GO:0021675 45 0.052
mechanosensory lateral line system development GO:0048881 49 0.051
regulation of response to stimulus GO:0048583 269 0.051
regulation of response to oxidative stress GO:1902882 2 0.050
neurotransmitter transport GO:0006836 2 0.050
embryonic skeletal system morphogenesis GO:0048704 93 0.049
cell part morphogenesis GO:0032990 246 0.049
regulation of cell communication GO:0010646 232 0.049
organonitrogen compound metabolic process GO:1901564 74 0.048
camera type eye morphogenesis GO:0048593 108 0.048
cell projection organization GO:0030030 284 0.047
regulation of retina development in camera type eye GO:1902866 2 0.044
regulation of signaling GO:0023051 235 0.044
detection of abiotic stimulus GO:0009582 24 0.044
myeloid cell differentiation GO:0030099 86 0.044
positive regulation of synapse assembly GO:0051965 1 0.043
otic vesicle development GO:0071599 42 0.043
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.042
centrosome localization GO:0051642 1 0.040
locomotion GO:0040011 313 0.040
erythrocyte homeostasis GO:0034101 55 0.040
regulation of biosynthetic process GO:0009889 250 0.040
epithelial cell differentiation GO:0030855 116 0.039
lens fiber cell morphogenesis GO:0070309 3 0.039
negative regulation of multicellular organismal process GO:0051241 69 0.039
lateral line system development GO:0048925 76 0.039
cell death GO:0008219 121 0.037
negative regulation of feeding behavior GO:2000252 2 0.037
retina layer formation GO:0010842 24 0.037
cell cell signaling GO:0007267 52 0.037
regulation of multicellular organism growth GO:0040014 4 0.036
specification of symmetry GO:0009799 204 0.036
death GO:0016265 121 0.036
negative regulation of cell development GO:0010721 26 0.036
negative regulation of signaling GO:0023057 96 0.035
organic substance transport GO:0071702 58 0.035
organic substance biosynthetic process GO:1901576 289 0.035
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.035
mitochondrion organization GO:0007005 4 0.035
central nervous system neuron development GO:0021954 29 0.035
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.035
multicellular organism growth GO:0035264 4 0.034
neuron projection development GO:0031175 180 0.034
otic vesicle morphogenesis GO:0071600 34 0.034
synaptic vesicle localization GO:0097479 1 0.033
organelle fusion GO:0048284 3 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
neurotransmitter secretion GO:0007269 2 0.032
endocrine system development GO:0035270 65 0.032
heart development GO:0007507 313 0.032
cellular response to stress GO:0033554 62 0.031
neurological system process GO:0050877 62 0.031
proepicardium development GO:0003342 4 0.031
morphogenesis of an epithelium GO:0002009 333 0.030
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.030
regulation of binding GO:0051098 3 0.030
membrane organization GO:0061024 21 0.029
circulatory system process GO:0003013 87 0.029
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.029
regulation of cytokine mediated signaling pathway GO:0001959 3 0.029
negative regulation of cell projection organization GO:0031345 9 0.028
hematopoietic or lymphoid organ development GO:0048534 191 0.028
regulation of collateral sprouting in absence of injury GO:0048696 4 0.028
regulation of membrane repolarization GO:0060306 1 0.028
response to external stimulus GO:0009605 264 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
fat soluble vitamin metabolic process GO:0006775 4 0.028
neuromast development GO:0048884 46 0.028
hemopoiesis GO:0030097 183 0.027
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.027
cellular component biogenesis GO:0044085 178 0.027
negative regulation of metabolic process GO:0009892 86 0.027
regulation of oxidative stress induced cell death GO:1903201 2 0.027
regulation of cell differentiation GO:0045595 142 0.027
aging GO:0007568 2 0.027
ear development GO:0043583 127 0.027
single organism metabolic process GO:0044710 217 0.027
positive regulation of jak stat cascade GO:0046427 2 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
growth GO:0040007 174 0.026
anion transport GO:0006820 38 0.026
fin morphogenesis GO:0033334 53 0.026
equilibrioception GO:0050957 2 0.025
skeletal system development GO:0001501 181 0.025
alcohol biosynthetic process GO:0046165 2 0.025
small molecule metabolic process GO:0044281 77 0.025
negative regulation of developmental process GO:0051093 65 0.025
neuroblast proliferation GO:0007405 2 0.025
carboxylic acid transport GO:0046942 8 0.025
regulation of metabolic process GO:0019222 359 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
response to chemical GO:0042221 320 0.024
cellular biosynthetic process GO:0044249 286 0.024
anterior lateral line system development GO:0048898 9 0.024
l amino acid transport GO:0015807 1 0.024
heart contraction GO:0060047 71 0.023
stem cell differentiation GO:0048863 117 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of neuron projection regeneration GO:0070570 7 0.023
positive regulation of response to external stimulus GO:0032103 9 0.023
digestive tract morphogenesis GO:0048546 231 0.022
cell motility GO:0048870 244 0.022
head development GO:0060322 303 0.022
cardiac atrium development GO:0003230 4 0.021
negative regulation of signal transduction GO:0009968 94 0.021
vasculature development GO:0001944 278 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
determination of left right symmetry GO:0007368 179 0.020
localization of cell GO:0051674 244 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
single organism membrane organization GO:0044802 20 0.020
detection of stimulus involved in sensory perception GO:0050906 21 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
ameboidal type cell migration GO:0001667 143 0.020
chemotaxis GO:0006935 104 0.020
cellular component disassembly GO:0022411 1 0.020
erythrocyte differentiation GO:0030218 54 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.019
gtp catabolic process GO:0006184 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
membrane repolarization GO:0086009 2 0.019
auditory receptor cell fate commitment GO:0009912 4 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
apoptotic process GO:0006915 116 0.019
exocytosis GO:0006887 1 0.019
regulation of neuron projection development GO:0010975 40 0.019
negative regulation of cellular component organization GO:0051129 16 0.019
intracellular signal transduction GO:0035556 85 0.019
regulation of localization GO:0032879 104 0.019
digestive tract development GO:0048565 265 0.019
cardiocyte differentiation GO:0035051 44 0.018
embryonic skeletal system development GO:0048706 97 0.018
regulation of cellular response to stress GO:0080135 20 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of cell shape GO:0008360 1 0.018
gtp metabolic process GO:0046039 4 0.018
regionalization GO:0003002 274 0.018
endocardium morphogenesis GO:0003160 4 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
cellular component assembly involved in morphogenesis GO:0010927 107 0.018
regulation of heart growth GO:0060420 2 0.018
iron ion homeostasis GO:0055072 4 0.017
establishment of localization in cell GO:0051649 77 0.017
specification of organ identity GO:0010092 2 0.017
mitochondrion morphogenesis GO:0070584 2 0.017
septum transversum development GO:0003343 4 0.017
synaptic transmission GO:0007268 35 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
ion homeostasis GO:0050801 41 0.017
positive regulation of transport GO:0051050 2 0.017
regulation of mitochondrion organization GO:0010821 1 0.017
regulation of neural retina development GO:0061074 2 0.017
establishment of organelle localization GO:0051656 45 0.017
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.017
fat soluble vitamin biosynthetic process GO:0042362 2 0.017
cell projection morphogenesis GO:0048858 244 0.017
protein targeting to membrane GO:0006612 1 0.017
regulation of apoptotic process GO:0042981 98 0.016
digestive system development GO:0055123 289 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of primary metabolic process GO:0080090 311 0.016
skeletal system morphogenesis GO:0048705 102 0.016
homeostasis of number of cells GO:0048872 62 0.016
single organism transport GO:0044765 206 0.016
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.016
cellular component assembly GO:0022607 170 0.016
neuron projection regeneration GO:0031102 16 0.016
innervation GO:0060384 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
organelle localization GO:0051640 49 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
macromolecular complex disassembly GO:0032984 1 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.015
determination of bilateral symmetry GO:0009855 204 0.015
cellular pigmentation GO:0033059 30 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
regulation of developmental growth GO:0048638 38 0.015
mononuclear cell migration GO:0071674 1 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.015
cellular ketone metabolic process GO:0042180 11 0.015
hepaticobiliary system development GO:0061008 98 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
retinal cell programmed cell death GO:0046666 2 0.015
amine metabolic process GO:0009308 2 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
cellular component morphogenesis GO:0032989 336 0.014
intrinsic apoptotic signaling pathway GO:0097193 20 0.014
auditory receptor cell morphogenesis GO:0002093 4 0.014
mesenchymal cell development GO:0014031 78 0.014
leukocyte proliferation GO:0070661 1 0.014
cytokine mediated signaling pathway GO:0019221 7 0.014
biosynthetic process GO:0009058 294 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
multi organism process GO:0051704 134 0.014
tissue migration GO:0090130 37 0.014
synapse organization GO:0050808 21 0.014
lens fiber cell development GO:0070307 3 0.014
energy reserve metabolic process GO:0006112 2 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of cell death GO:0010941 103 0.014
cilium organization GO:0044782 71 0.014
homeostatic process GO:0042592 142 0.014
amino acid transport GO:0006865 2 0.014
positive regulation of secretion GO:0051047 1 0.014
response to oxidative stress GO:0006979 11 0.014
pigmentation GO:0043473 85 0.013
central nervous system neuron axonogenesis GO:0021955 18 0.013
myofibril assembly GO:0030239 48 0.013
phosphorus metabolic process GO:0006793 109 0.013
maintenance of location GO:0051235 4 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
response to vitamin GO:0033273 3 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
dicarboxylic acid transport GO:0006835 1 0.013
blood vessel endothelial cell migration GO:0043534 18 0.013
chemical homeostasis GO:0048878 49 0.013
osteoclast differentiation GO:0030316 1 0.013
regulation of axon regeneration GO:0048679 7 0.013
embryonic hemopoiesis GO:0035162 53 0.013
ear morphogenesis GO:0042471 64 0.013
regulation of nervous system development GO:0051960 90 0.013
establishment of monopolar cell polarity GO:0061162 2 0.013
response to organic substance GO:0010033 153 0.013
protein complex disassembly GO:0043241 1 0.013
lipid storage GO:0019915 1 0.013
cation transmembrane transport GO:0098655 65 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
ion transport GO:0006811 114 0.012
granulocyte migration GO:0097530 11 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
stem cell division GO:0017145 1 0.012
programmed cell death GO:0012501 119 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
single organism biosynthetic process GO:0044711 71 0.012
protein import into nucleus GO:0006606 3 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
organic acid metabolic process GO:0006082 31 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
sensory perception GO:0007600 39 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
phagocytosis GO:0006909 3 0.012
post embryonic organ development GO:0048569 4 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
adult behavior GO:0030534 2 0.012
mesenchyme development GO:0060485 127 0.012
establishment of apical basal cell polarity GO:0035089 2 0.012
determination of intestine left right asymmetry GO:0071908 2 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
developmental cell growth GO:0048588 52 0.012
pigment cell differentiation GO:0050931 38 0.012
regulation of behavior GO:0050795 24 0.012
synaptic vesicle transport GO:0048489 1 0.012
ion transmembrane transport GO:0034220 91 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
multicellular organismal metabolic process GO:0044236 2 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of cell development GO:0060284 100 0.011
cell fate commitment GO:0045165 99 0.011
pancreas development GO:0031016 84 0.011
cellular response to nutrient levels GO:0031669 2 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
positive regulation of axon regeneration GO:0048680 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
negative regulation of cellular process GO:0048523 283 0.011
innate immune response GO:0045087 13 0.011
formation of primary germ layer GO:0001704 62 0.011
establishment of epithelial cell apical basal polarity GO:0045198 2 0.011
epithelial cell migration GO:0010631 25 0.011
regulation of response to stress GO:0080134 36 0.011
blood vessel development GO:0001568 246 0.011
ovarian follicle development GO:0001541 2 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
regulation of cardiac muscle tissue development GO:0055024 1 0.011
negative regulation of oxidative stress induced cell death GO:1903202 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of melanocyte differentiation GO:0045634 2 0.011
heart process GO:0003015 71 0.011
reflex GO:0060004 2 0.011
retinal rod cell development GO:0046548 4 0.011
regulation of endothelial cell differentiation GO:0045601 3 0.011
heterocycle metabolic process GO:0046483 290 0.011
nucleic acid metabolic process GO:0090304 244 0.011
regulation of cellular component organization GO:0051128 86 0.011
negative regulation of neuron differentiation GO:0045665 10 0.011
regeneration GO:0031099 91 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
synaptic vesicle recycling GO:0036465 1 0.010
gastrulation GO:0007369 208 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
response to corticosteroid GO:0031960 1 0.010
glial cell migration GO:0008347 3 0.010
embryonic heart tube formation GO:0003144 1 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
tube closure GO:0060606 1 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
negative regulation of nervous system development GO:0051961 22 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
erythrocyte development GO:0048821 24 0.010
stem cell proliferation GO:0072089 4 0.010
developmental growth GO:0048589 166 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
regulation of protein complex assembly GO:0043254 3 0.010
negative regulation of reproductive process GO:2000242 3 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
chordate embryonic development GO:0043009 271 0.010
neuroepithelial cell differentiation GO:0060563 26 0.010

ctbp2l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.038
disease of anatomical entity DOID:7 0 0.038
hematopoietic system disease DOID:74 0 0.038
auditory system disease DOID:2742 0 0.023
nonsyndromic deafness DOID:0050563 0 0.023
sensory system disease DOID:0050155 0 0.023
nervous system disease DOID:863 0 0.023