Danio rerio

18 known processes

si:dkey-25o1.2

si:dkey-25o1.2

si:dkey-25o1.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.148
neuron differentiation GO:0030182 353 0.135
cellular component movement GO:0006928 335 0.064
single fertilization GO:0007338 3 0.059
aging GO:0007568 2 0.058
generation of neurons GO:0048699 385 0.056
positive regulation of cellular component biogenesis GO:0044089 3 0.053
cellular component morphogenesis GO:0032989 336 0.048
response to amino acid GO:0043200 2 0.047
digestive system development GO:0055123 289 0.045
adult behavior GO:0030534 2 0.043
regulation of synapse organization GO:0050807 3 0.043
regulation of stem cell differentiation GO:2000736 4 0.042
stem cell maintenance GO:0019827 4 0.042
cell morphogenesis GO:0000902 289 0.042
gastrulation GO:0007369 208 0.040
regulation of synapse assembly GO:0051963 3 0.039
regulation of cell shape GO:0008360 1 0.038
synaptic growth at neuromuscular junction GO:0051124 2 0.037
cell projection morphogenesis GO:0048858 244 0.037
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.036
digestive tract development GO:0048565 265 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
protein localization to nucleus GO:0034504 3 0.034
cell migration GO:0016477 237 0.033
negative regulation of cellular process GO:0048523 283 0.032
wound healing GO:0042060 90 0.032
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.032
response to drug GO:0042493 3 0.032
multicellular organismal metabolic process GO:0044236 2 0.031
signal transduction GO:0007165 455 0.031
regulation of signal transduction GO:0009966 225 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
protein heterooligomerization GO:0051291 1 0.031
neuron neuron synaptic transmission GO:0007270 1 0.031
maintenance of location GO:0051235 4 0.031
organic substance biosynthetic process GO:1901576 289 0.030
fertilization GO:0009566 3 0.030
cell motility GO:0048870 244 0.029
response to stress GO:0006950 263 0.029
negative regulation of ras protein signal transduction GO:0046580 1 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
cellular response to external stimulus GO:0071496 2 0.027
cellular response to nutrient levels GO:0031669 2 0.027
digestive tract morphogenesis GO:0048546 231 0.027
lipid catabolic process GO:0016042 4 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
regulation of cell projection assembly GO:0060491 4 0.026
astrocyte differentiation GO:0048708 1 0.026
localization of cell GO:0051674 244 0.025
developmental growth GO:0048589 166 0.024
cation transmembrane transport GO:0098655 65 0.024
phagocytosis GO:0006909 3 0.024
multicellular organism growth GO:0035264 4 0.024
response to external stimulus GO:0009605 264 0.024
guanosine containing compound metabolic process GO:1901068 4 0.023
ameboidal type cell migration GO:0001667 143 0.023
lipid storage GO:0019915 1 0.023
regulation of metabolic process GO:0019222 359 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
collagen metabolic process GO:0032963 2 0.023
growth GO:0040007 174 0.023
mesenchyme development GO:0060485 127 0.023
cell projection organization GO:0030030 284 0.022
zymogen activation GO:0031638 3 0.022
nucleoside monophosphate catabolic process GO:0009125 4 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
locomotion GO:0040011 313 0.021
regulation of catenin import into nucleus GO:0035412 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
nuclear migration GO:0007097 3 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
germ line stem cell maintenance GO:0030718 2 0.021
neuroblast proliferation GO:0007405 2 0.020
meiotic nuclear division GO:0007126 4 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
reflex GO:0060004 2 0.020
head development GO:0060322 303 0.020
oocyte maturation GO:0001556 4 0.020
apoptotic process involved in development GO:1902742 2 0.020
stem cell proliferation GO:0072089 4 0.020
regulation of binding GO:0051098 3 0.020
response to chemical GO:0042221 320 0.020
meiotic cell cycle process GO:1903046 3 0.020
gtp catabolic process GO:0006184 2 0.020
cellular ketone metabolic process GO:0042180 11 0.020
inorganic ion transmembrane transport GO:0098660 57 0.020
positive regulation of cytokine production GO:0001819 2 0.020
protein import GO:0017038 3 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
central nervous system development GO:0007417 387 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of reproductive process GO:2000241 4 0.019
rna localization GO:0006403 4 0.019
protein acetylation GO:0006473 2 0.019
cell part morphogenesis GO:0032990 246 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
eye development GO:0001654 277 0.019
lateral inhibition GO:0046331 1 0.019
apoptotic process GO:0006915 116 0.019
amine metabolic process GO:0009308 2 0.019
tissue regeneration GO:0042246 74 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
positive regulation of muscle organ development GO:0048636 1 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
negative regulation of biological process GO:0048519 304 0.019
neuron projection morphogenesis GO:0048812 161 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
cellular component disassembly GO:0022411 1 0.018
transmembrane transport GO:0055085 120 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
muscle structure development GO:0061061 196 0.018
protein targeting to nucleus GO:0044744 3 0.018
specification of symmetry GO:0009799 204 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
calcium ion dependent exocytosis GO:0017156 1 0.018
locomotor rhythm GO:0045475 3 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
collagen biosynthetic process GO:0032964 2 0.018
nuclear export GO:0051168 1 0.018
positive regulation of protein polymerization GO:0032273 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
synaptic transmission glycinergic GO:0060012 1 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
neurotransmitter transport GO:0006836 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of sodium ion transport GO:0002028 2 0.017
cellular protein catabolic process GO:0044257 4 0.017
multicellular organismal macromolecule metabolic process GO:0044259 2 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
immune system development GO:0002520 191 0.017
centrosome organization GO:0051297 1 0.017
cellular response to starvation GO:0009267 1 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
neurotransmitter secretion GO:0007269 2 0.017
sulfate transmembrane transport GO:1902358 2 0.017
system process GO:0003008 185 0.017
regulation of biosynthetic process GO:0009889 250 0.016
blood vessel development GO:0001568 246 0.016
protein polymerization GO:0051258 4 0.016
positive regulation of cell cycle GO:0045787 3 0.016
centrosome cycle GO:0007098 1 0.016
b cell activation GO:0042113 2 0.016
rna metabolic process GO:0016070 219 0.016
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.016
developmental programmed cell death GO:0010623 4 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
cellular biosynthetic process GO:0044249 286 0.016
heart development GO:0007507 313 0.016
peptidyl serine modification GO:0018209 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
post embryonic organ development GO:0048569 4 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
positive regulation of synapse assembly GO:0051965 1 0.016
protein dephosphorylation GO:0006470 3 0.016
neuron development GO:0048666 262 0.016
regulation of cell communication GO:0010646 232 0.016
positive regulation of catabolic process GO:0009896 4 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of membrane potential GO:0042391 23 0.015
multi organism process GO:0051704 134 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
protein homooligomerization GO:0051260 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
nuclear transport GO:0051169 4 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
cellular amine metabolic process GO:0044106 2 0.015
meiosis i GO:0007127 1 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
connective tissue development GO:0061448 99 0.015
regulation of tube size GO:0035150 2 0.015
glial cell migration GO:0008347 3 0.015
regulation of response to stimulus GO:0048583 269 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
negative regulation of intracellular transport GO:0032387 3 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
centrosome duplication GO:0051298 1 0.015
protein acylation GO:0043543 3 0.015
startle response GO:0001964 4 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of developmental process GO:0050793 247 0.015
response to nutrient GO:0007584 3 0.015
regulation of mrna processing GO:0050684 3 0.015
lamellipodium organization GO:0097581 1 0.015
nitrogen compound metabolic process GO:0006807 319 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of blood vessel size GO:0050880 2 0.015
multi organism cellular process GO:0044764 2 0.015
actin filament based movement GO:0030048 1 0.015
tube morphogenesis GO:0035239 349 0.015
taxis GO:0042330 109 0.015
regulation of filopodium assembly GO:0051489 2 0.014
response to corticosteroid GO:0031960 1 0.014
sensory perception of smell GO:0007608 2 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
regulation of wound healing GO:0061041 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
positive regulation of translation GO:0045727 1 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
macroautophagy GO:0016236 1 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
protein metabolic process GO:0019538 183 0.014
regulation of organ growth GO:0046620 3 0.014
trabecula morphogenesis GO:0061383 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
female gonad development GO:0008585 4 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
fin regeneration GO:0031101 51 0.014
endosomal transport GO:0016197 2 0.014
vasculature development GO:0001944 278 0.014
single organism localization GO:1902578 225 0.014
regulation of transporter activity GO:0032409 2 0.014
organic acid catabolic process GO:0016054 3 0.014
single organism nuclear import GO:1902593 3 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of protein catabolic process GO:0042176 1 0.014
pole plasm assembly GO:0007315 4 0.014
heterocycle metabolic process GO:0046483 290 0.014
viral process GO:0016032 1 0.014
microtubule organizing center organization GO:0031023 1 0.014
epidermal cell fate specification GO:0009957 4 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
protein complex disassembly GO:0043241 1 0.014
single organism biosynthetic process GO:0044711 71 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
transport GO:0006810 220 0.014
vacuolar transport GO:0007034 2 0.014
secondary metabolic process GO:0019748 3 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
negative regulation of mitosis GO:0045839 3 0.013
sensory organ development GO:0007423 393 0.013
organic acid metabolic process GO:0006082 31 0.013
neuronal action potential GO:0019228 18 0.013
negative regulation of defense response GO:0031348 2 0.013
positive regulation of cellular process GO:0048522 201 0.013
regulation of protein targeting GO:1903533 2 0.013
macromolecular complex disassembly GO:0032984 1 0.013
negative regulation of nuclear division GO:0051784 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
regulation of primary metabolic process GO:0080090 311 0.013
positive regulation of immune effector process GO:0002699 3 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
regulation of signaling GO:0023051 235 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
multi organism reproductive process GO:0044703 36 0.013
renal tubule morphogenesis GO:0061333 1 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
cell cycle arrest GO:0007050 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of gtpase activity GO:0043087 2 0.013
collagen fibril organization GO:0030199 1 0.013
morphogenesis of an epithelial sheet GO:0002011 49 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of biomineral tissue development GO:0070167 2 0.013
extracellular structure organization GO:0043062 27 0.013
regulation of cell development GO:0060284 100 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
positive regulation of muscle cell differentiation GO:0051149 1 0.013
neuron projection development GO:0031175 180 0.013
small molecule metabolic process GO:0044281 77 0.013
nucleic acid transport GO:0050657 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
positive regulation of transport GO:0051050 2 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
establishment of rna localization GO:0051236 3 0.013
gene expression GO:0010467 252 0.012
brain development GO:0007420 293 0.012
regulation of protein transport GO:0051223 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
peptidyl threonine modification GO:0018210 1 0.012
regulation of oocyte development GO:0060281 3 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
mitochondrial transport GO:0006839 2 0.012
response to monosaccharide GO:0034284 3 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
regulation of protein complex assembly GO:0043254 3 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
apoptotic process involved in morphogenesis GO:0060561 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
autophagy GO:0006914 4 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
protein import into nucleus GO:0006606 3 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
antimicrobial humoral response GO:0019730 2 0.012
membrane hyperpolarization GO:0060081 1 0.012
single organism transport GO:0044765 206 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
regulation of circadian rhythm GO:0042752 4 0.012
rna transport GO:0050658 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
response to vitamin GO:0033273 3 0.012
leukocyte proliferation GO:0070661 1 0.012
nucleobase containing compound transport GO:0015931 2 0.012
hormone biosynthetic process GO:0042446 3 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
determination of left right symmetry GO:0007368 179 0.012
regulation of protein polymerization GO:0032271 2 0.012
cellular response to retinoic acid GO:0071300 1 0.012
rna biosynthetic process GO:0032774 181 0.012
response to uv GO:0009411 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
regeneration GO:0031099 91 0.012
negative regulation of blood circulation GO:1903523 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.011
cellular lipid catabolic process GO:0044242 3 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
small molecule catabolic process GO:0044282 3 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
nuclear import GO:0051170 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
cellular response to oxygen levels GO:0071453 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
response to organic substance GO:0010033 153 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
axon development GO:0061564 166 0.011
epiboly GO:0090504 41 0.011
gland development GO:0048732 143 0.011
negative regulation of catabolic process GO:0009895 3 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
chemotaxis GO:0006935 104 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
negative regulation of signaling GO:0023057 96 0.011
regulation of dna replication GO:0006275 3 0.011
stem cell differentiation GO:0048863 117 0.011
stem cell development GO:0048864 82 0.011
membrane repolarization GO:0086009 2 0.011
response to glucose GO:0009749 3 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
sleep GO:0030431 1 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of reproductive process GO:2000243 2 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
intramembranous ossification GO:0001957 3 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
establishment of localization GO:0051234 244 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
response to unfolded protein GO:0006986 2 0.011
actin filament polymerization GO:0030041 2 0.011
positive regulation of biological process GO:0048518 253 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
axonogenesis GO:0007409 152 0.011
atp catabolic process GO:0006200 4 0.011
stem cell division GO:0017145 1 0.011
sensory system development GO:0048880 76 0.010
camera type eye development GO:0043010 222 0.010
regulation of gene expression GO:0010468 265 0.010
muscle organ development GO:0007517 101 0.010
tissue remodeling GO:0048771 4 0.010
oxoacid metabolic process GO:0043436 31 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of glial cell differentiation GO:0045685 4 0.010
somatic muscle development GO:0007525 4 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
oxalate transport GO:0019532 1 0.010
negative regulation of gene expression GO:0010629 65 0.010
negative regulation of signal transduction GO:0009968 94 0.010
sulfur compound transport GO:0072348 3 0.010
negative regulation of kinase activity GO:0033673 4 0.010
regulation of cell activation GO:0050865 1 0.010
establishment of endothelial barrier GO:0061028 3 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
cellular response to hypoxia GO:0071456 1 0.010
mesoderm development GO:0007498 88 0.010
blood vessel morphogenesis GO:0048514 216 0.010
glutamate receptor signaling pathway GO:0007215 1 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
ion transmembrane transport GO:0034220 91 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
cell substrate adhesion GO:0031589 4 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
transmission of nerve impulse GO:0019226 19 0.010
single organism organelle organization GO:1902589 199 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
calcium ion import GO:0070509 4 0.010
xenobiotic metabolic process GO:0006805 4 0.010
endocrine process GO:0050886 2 0.010
positive regulation of histone modification GO:0031058 1 0.010
cell substrate junction assembly GO:0007044 2 0.010
cell aging GO:0007569 2 0.010

si:dkey-25o1.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.020
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
disease of cellular proliferation DOID:14566 0 0.012
bone development disease DOID:0080006 0 0.012