Danio rerio

55 known processes

zgc:77409

zgc:77409

(Aliases: bace1,MGC77409)

zgc:77409 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 244 0.454
cellular component movement GO:0006928 335 0.358
localization of cell GO:0051674 244 0.239
cell migration GO:0016477 237 0.177
ameboidal type cell migration GO:0001667 143 0.107
fertilization GO:0009566 3 0.096
locomotion GO:0040011 313 0.093
regulation of signaling GO:0023051 235 0.090
cell surface receptor signaling pathway GO:0007166 325 0.090
neurotransmitter transport GO:0006836 2 0.085
monoamine transport GO:0015844 1 0.084
system process GO:0003008 185 0.078
protein metabolic process GO:0019538 183 0.077
regulation of synaptic plasticity GO:0048167 1 0.076
synaptic growth at neuromuscular junction GO:0051124 2 0.072
response to abiotic stimulus GO:0009628 122 0.068
embryonic organ development GO:0048568 381 0.065
larval development GO:0002164 2 0.064
regulation of biological quality GO:0065008 263 0.063
sensory organ development GO:0007423 393 0.063
regulation of cell communication GO:0010646 232 0.061
regulation of signal transduction GO:0009966 225 0.059
negative regulation of cellular process GO:0048523 283 0.059
transmission of nerve impulse GO:0019226 19 0.058
nitrogen compound metabolic process GO:0006807 319 0.055
regulation of intracellular protein transport GO:0033157 3 0.055
regulation of cell shape GO:0008360 1 0.055
exocytosis GO:0006887 1 0.054
regulation of response to stimulus GO:0048583 269 0.053
establishment of localization GO:0051234 244 0.052
blood vessel development GO:0001568 246 0.052
aging GO:0007568 2 0.051
death GO:0016265 121 0.051
gtp catabolic process GO:0006184 2 0.050
guanosine containing compound catabolic process GO:1901069 2 0.050
transport GO:0006810 220 0.048
multicellular organismal signaling GO:0035637 22 0.048
gtp metabolic process GO:0046039 4 0.047
response to chemical GO:0042221 320 0.047
neuron development GO:0048666 262 0.046
signal transduction GO:0007165 455 0.046
guanosine containing compound metabolic process GO:1901068 4 0.045
positive regulation of cellular component biogenesis GO:0044089 3 0.043
positive regulation of transport GO:0051050 2 0.042
maintenance of location GO:0051235 4 0.041
single organism localization GO:1902578 225 0.041
action potential GO:0001508 19 0.041
cation transport GO:0006812 81 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.040
adult behavior GO:0030534 2 0.040
amine metabolic process GO:0009308 2 0.039
regulation of reactive oxygen species metabolic process GO:2000377 2 0.039
phosphate containing compound metabolic process GO:0006796 108 0.037
regulation of protein transport GO:0051223 3 0.037
negative regulation of mapk cascade GO:0043409 4 0.037
regulation of purine nucleotide catabolic process GO:0033121 2 0.036
neuronal action potential GO:0019228 18 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
behavior GO:0007610 74 0.035
response to topologically incorrect protein GO:0035966 2 0.035
neurotransmitter secretion GO:0007269 2 0.034
lamellipodium organization GO:0097581 1 0.034
single organism metabolic process GO:0044710 217 0.034
pigment granule localization GO:0051875 25 0.034
chemosensory behavior GO:0007635 1 0.034
cell morphogenesis GO:0000902 289 0.034
regulation of erk1 and erk2 cascade GO:0070372 4 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
negative regulation of intracellular protein transport GO:0090317 3 0.033
organelle localization GO:0051640 49 0.033
positive regulation of secretion GO:0051047 1 0.033
regulation of cell motility GO:2000145 46 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
axon ensheathment GO:0008366 18 0.032
eye development GO:0001654 277 0.032
programmed cell death GO:0012501 119 0.031
posterior lateral line system development GO:0048915 46 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
g protein coupled receptor signaling pathway GO:0007186 74 0.031
vasculature development GO:0001944 278 0.031
neuron differentiation GO:0030182 353 0.030
retina development in camera type eye GO:0060041 146 0.030
negative regulation of biological process GO:0048519 304 0.030
regulation of muscle hypertrophy GO:0014743 2 0.030
cellular response to external stimulus GO:0071496 2 0.030
positive regulation of biological process GO:0048518 253 0.030
single fertilization GO:0007338 3 0.030
positive regulation of wound healing GO:0090303 1 0.030
regulation of system process GO:0044057 40 0.029
cell part morphogenesis GO:0032990 246 0.029
regulation of protein targeting GO:1903533 2 0.029
response to drug GO:0042493 3 0.029
regulation of locomotion GO:0040012 55 0.029
blood vessel morphogenesis GO:0048514 216 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.028
cytoplasm organization GO:0007028 4 0.028
cell morphogenesis involved in differentiation GO:0000904 195 0.028
regulation of cell projection assembly GO:0060491 4 0.028
meiotic nuclear division GO:0007126 4 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
cell projection organization GO:0030030 284 0.027
generation of neurons GO:0048699 385 0.027
cellular component disassembly GO:0022411 1 0.027
ensheathment of neurons GO:0007272 18 0.027
response to glucose GO:0009749 3 0.027
positive regulation of catabolic process GO:0009896 4 0.027
regulation of metabolic process GO:0019222 359 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
ras protein signal transduction GO:0007265 7 0.026
positive regulation of secretion by cell GO:1903532 1 0.026
neurological system process GO:0050877 62 0.026
regulation of gtp catabolic process GO:0033124 2 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
central nervous system neuron development GO:0021954 29 0.026
negative regulation of signaling GO:0023057 96 0.026
cognition GO:0050890 1 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
positive regulation of gtp catabolic process GO:0033126 1 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of glial cell differentiation GO:0045685 4 0.025
cell projection morphogenesis GO:0048858 244 0.024
protein secretion GO:0009306 1 0.024
multicellular organism growth GO:0035264 4 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
release of sequestered calcium ion into cytosol GO:0051209 3 0.024
camera type eye development GO:0043010 222 0.023
spermatid development GO:0007286 2 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
phosphorus metabolic process GO:0006793 109 0.023
somatic muscle development GO:0007525 4 0.023
cell projection assembly GO:0030031 64 0.022
hepaticobiliary system development GO:0061008 98 0.022
apoptotic process GO:0006915 116 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.022
regulation of localization GO:0032879 104 0.022
nuclear transport GO:0051169 4 0.022
regulation of cellular metabolic process GO:0031323 320 0.021
mechanosensory behavior GO:0007638 2 0.021
regulation of synapse organization GO:0050807 3 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of protein catabolic process GO:0042176 1 0.021
axon guidance GO:0007411 86 0.021
cell substrate adhesion GO:0031589 4 0.021
hormone secretion GO:0046879 2 0.021
cellular amine metabolic process GO:0044106 2 0.021
regulation of hormone secretion GO:0046883 2 0.020
transmembrane transport GO:0055085 120 0.020
cellular component morphogenesis GO:0032989 336 0.020
heterocycle metabolic process GO:0046483 290 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
nucleocytoplasmic transport GO:0006913 4 0.019
establishment of organelle localization GO:0051656 45 0.019
eye morphogenesis GO:0048592 144 0.019
carbohydrate homeostasis GO:0033500 1 0.019
lamellipodium assembly GO:0030032 1 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
regulation of transport GO:0051049 45 0.019
regulation of primary metabolic process GO:0080090 311 0.019
regulation of gtpase activity GO:0043087 2 0.018
septum transversum development GO:0003343 4 0.018
gene expression GO:0010467 252 0.018
neuron projection development GO:0031175 180 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
regulation of wound healing GO:0061041 2 0.018
angiogenesis GO:0001525 158 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
homeostatic process GO:0042592 142 0.018
single organism transport GO:0044765 206 0.018
positive regulation of neuron death GO:1901216 1 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
olfactory lobe development GO:0021988 4 0.018
atp catabolic process GO:0006200 4 0.018
meiotic cell cycle process GO:1903046 3 0.018
cellular component biogenesis GO:0044085 178 0.018
regulation of developmental process GO:0050793 247 0.017
taxis GO:0042330 109 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
intracellular mrna localization GO:0008298 1 0.017
axonogenesis GO:0007409 152 0.017
response to stress GO:0006950 263 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
negative regulation of kinase activity GO:0033673 4 0.017
regulation of apoptotic process GO:0042981 98 0.017
circulatory system process GO:0003013 87 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
cranial nerve development GO:0021545 42 0.017
cellular ketone metabolic process GO:0042180 11 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
hormone transport GO:0009914 2 0.016
regulation of membrane potential GO:0042391 23 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
regionalization GO:0003002 274 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
immune system development GO:0002520 191 0.016
protein acylation GO:0043543 3 0.016
peptide transport GO:0015833 1 0.016
protein complex disassembly GO:0043241 1 0.016
nucleic acid templated transcription GO:0097659 181 0.016
posterior lateral line development GO:0048916 38 0.015
synaptic vesicle localization GO:0097479 1 0.015
synaptic transmission glycinergic GO:0060012 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
epithelium migration GO:0090132 25 0.015
head development GO:0060322 303 0.015
muscle structure development GO:0061061 196 0.015
regulation of cellular component movement GO:0051270 55 0.015
negative regulation of protein transport GO:0051224 3 0.015
response to light stimulus GO:0009416 46 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
rna localization GO:0006403 4 0.015
macromolecular complex disassembly GO:0032984 1 0.015
neuron projection morphogenesis GO:0048812 161 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
phagocytosis GO:0006909 3 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
cellular component assembly GO:0022607 170 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
lens fiber cell development GO:0070307 3 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
glucose homeostasis GO:0042593 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
nerve development GO:0021675 45 0.015
biosynthetic process GO:0009058 294 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
protein polymerization GO:0051258 4 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
small molecule metabolic process GO:0044281 77 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of reproductive process GO:2000241 4 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
single organism organelle organization GO:1902589 199 0.014
spermatid differentiation GO:0048515 2 0.014
chordate embryonic development GO:0043009 271 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
protein import into nucleus GO:0006606 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
mechanosensory lateral line system development GO:0048881 49 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
nuclear import GO:0051170 3 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
positive regulation of blood circulation GO:1903524 2 0.014
regulation of filopodium assembly GO:0051489 2 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
macromolecule localization GO:0033036 54 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
meiotic chromosome segregation GO:0045132 3 0.014
regulation of synapse assembly GO:0051963 3 0.014
negative regulation of catabolic process GO:0009895 3 0.014
photoreceptor cell fate commitment GO:0046552 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
protein homooligomerization GO:0051260 3 0.013
growth GO:0040007 174 0.013
regulation of blood pressure GO:0008217 1 0.013
peptidyl serine modification GO:0018209 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
developmental growth GO:0048589 166 0.013
cellular response to nutrient levels GO:0031669 2 0.013
response to organic substance GO:0010033 153 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
response to carbohydrate GO:0009743 3 0.013
cellular response to organic substance GO:0071310 105 0.013
multicellular organismal response to stress GO:0033555 2 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
central nervous system myelination GO:0022010 2 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
establishment of localization in cell GO:0051649 77 0.012
response to hypoxia GO:0001666 25 0.012
microtubule based process GO:0007017 60 0.012
glial cell differentiation GO:0010001 42 0.012
regulation of membrane repolarization GO:0060306 1 0.012
glial cell proliferation GO:0014009 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
developmental programmed cell death GO:0010623 4 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
olfactory bulb development GO:0021772 4 0.012
regulation of protein binding GO:0043393 3 0.012
response to radiation GO:0009314 51 0.012
cellular protein modification process GO:0006464 100 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
protein complex assembly GO:0006461 30 0.012
protein targeting to membrane GO:0006612 1 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
cellular macromolecule localization GO:0070727 21 0.012
glial cell development GO:0021782 20 0.012
myeloid cell differentiation GO:0030099 86 0.012
sprouting angiogenesis GO:0002040 53 0.012
cell substrate junction assembly GO:0007044 2 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of catalytic activity GO:0050790 55 0.012
central nervous system development GO:0007417 387 0.012
cellular localization GO:0051641 97 0.012
toxin transport GO:1901998 2 0.012
regulation of programmed cell death GO:0043067 101 0.011
apoptotic process involved in morphogenesis GO:0060561 2 0.011
response to temperature stimulus GO:0009266 15 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
regulation of metal ion transport GO:0010959 4 0.011
mitotic cytokinesis GO:0000281 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of hemostasis GO:1900046 1 0.011
response to decreased oxygen levels GO:0036293 25 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of dendrite development GO:0050773 3 0.011
erythrocyte differentiation GO:0030218 54 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
specification of symmetry GO:0009799 204 0.011
brain development GO:0007420 293 0.011
multi organism reproductive process GO:0044703 36 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
cytokinesis GO:0000910 3 0.011
protein localization to nucleus GO:0034504 3 0.011
determination of left right symmetry GO:0007368 179 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.011
intracellular signal transduction GO:0035556 85 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
chemotaxis GO:0006935 104 0.010
heart process GO:0003015 71 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
glutamate receptor signaling pathway GO:0007215 1 0.010
protein targeting to nucleus GO:0044744 3 0.010
cation transmembrane transport GO:0098655 65 0.010
regulation of cell differentiation GO:0045595 142 0.010
retinal rod cell development GO:0046548 4 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
negative regulation of gliogenesis GO:0014014 1 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
nuclear export GO:0051168 1 0.010
sympathetic nervous system development GO:0048485 3 0.010
endocrine hormone secretion GO:0060986 2 0.010
lateral line development GO:0048882 66 0.010
multicellular organismal metabolic process GO:0044236 2 0.010

zgc:77409 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.014