Danio rerio

15 known processes

zic3

zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)

(Aliases: id:ibd2176,wu:fj52a10,cb807,wu:fq33c12)

zic3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell proliferation in forebrain GO:0021846 3 0.991
Zebrafish
larval development GO:0002164 2 0.896
Worm
astrocyte differentiation GO:0048708 1 0.865
forebrain development GO:0030900 96 0.864
Zebrafish
central nervous system development GO:0007417 387 0.827
Zebrafish
cell proliferation in midbrain GO:0033278 4 0.815
Zebrafish
smoothened signaling pathway GO:0007224 30 0.793
Zebrafish
axon development GO:0061564 166 0.762
canonical wnt signaling pathway GO:0060070 48 0.732
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.725
Human Zebrafish Mouse Worm Fly
forebrain morphogenesis GO:0048853 6 0.709
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.709
diencephalon development GO:0021536 58 0.701
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.698
Human Zebrafish Mouse Fly
regulation of signal transduction GO:0009966 225 0.692
Zebrafish
determination of left right symmetry GO:0007368 179 0.691
determination of bilateral symmetry GO:0009855 204 0.683
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.640
dna templated transcription initiation GO:0006352 1 0.633
Worm
ventricular system development GO:0021591 12 0.612
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.600
Human Zebrafish Mouse Fly
embryonic organ morphogenesis GO:0048562 274 0.588
Human Zebrafish Mouse
forebrain neuron fate commitment GO:0021877 1 0.578
specification of symmetry GO:0009799 204 0.573
regeneration GO:0031099 91 0.571
regulation of nucleic acid templated transcription GO:1903506 213 0.570
Human Zebrafish Mouse Fly
negative regulation of cellular process GO:0048523 283 0.565
Zebrafish
neural precursor cell proliferation GO:0061351 20 0.564
Zebrafish
digestive tract development GO:0048565 265 0.562
Human Fly
sensory organ development GO:0007423 393 0.561
Zebrafish
camera type eye development GO:0043010 222 0.560
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.559
Human Zebrafish Mouse Worm Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.557
Human Zebrafish Mouse Fly
cell proliferation in hindbrain GO:0021534 4 0.547
Zebrafish
eye development GO:0001654 277 0.537
Zebrafish
regulation of metabolic process GO:0019222 359 0.520
Human Zebrafish Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.508
Human Zebrafish Mouse Fly
forebrain regionalization GO:0021871 4 0.501
limbic system development GO:0021761 16 0.497
axis specification GO:0009798 43 0.497
cellular nitrogen compound metabolic process GO:0034641 290 0.479
Human Zebrafish Mouse Worm Fly
cellular component morphogenesis GO:0032989 336 0.475
regulation of oligodendrocyte differentiation GO:0048713 1 0.468
phosphorus metabolic process GO:0006793 109 0.457
enzyme linked receptor protein signaling pathway GO:0007167 106 0.456
Fly
transcription dna templated GO:0006351 181 0.447
Human Zebrafish Mouse Worm Fly
cell projection organization GO:0030030 284 0.441
embryonic organ development GO:0048568 381 0.440
Human Zebrafish Mouse
positive regulation of biological process GO:0048518 253 0.439
Human Mouse Fly
cell projection morphogenesis GO:0048858 244 0.438
positive regulation of metabolic process GO:0009893 108 0.434
Human Mouse Fly
mesenchymal cell differentiation GO:0048762 87 0.434
Zebrafish
skeletal system development GO:0001501 181 0.430
Zebrafish
single organism transport GO:0044765 206 0.430
generation of neurons GO:0048699 385 0.428
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.417
Human Zebrafish Mouse Worm Fly
neuron fate commitment GO:0048663 26 0.403
Worm
sensory organ morphogenesis GO:0090596 200 0.397
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.397
Human Zebrafish Mouse Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.396
Human Zebrafish Mouse Worm Fly
regulation of cell differentiation GO:0045595 142 0.390
regulation of macromolecule biosynthetic process GO:0010556 225 0.385
Human Zebrafish Mouse Fly
thalamus development GO:0021794 6 0.380
head development GO:0060322 303 0.375
Zebrafish
eye morphogenesis GO:0048592 144 0.371
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.368
Human Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.366
Human Zebrafish Mouse Fly
developmental process involved in reproduction GO:0003006 27 0.365
Worm
ectodermal placode development GO:0071696 37 0.363
ectodermal placode morphogenesis GO:0071697 32 0.363
regulation of nitrogen compound metabolic process GO:0051171 251 0.360
Human Zebrafish Mouse Fly
embryonic camera type eye development GO:0031076 29 0.358
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.348
nucleic acid metabolic process GO:0090304 244 0.347
Human Zebrafish Mouse Worm Fly
camera type eye morphogenesis GO:0048593 108 0.345
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.341
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.334
Human Zebrafish Mouse Worm Fly
cell morphogenesis GO:0000902 289 0.334
regulation of transcription dna templated GO:0006355 213 0.333
Human Zebrafish Mouse Fly
regulation of smoothened signaling pathway GO:0008589 18 0.326
Zebrafish
digestive system development GO:0055123 289 0.324
Human Fly
neural crest formation GO:0014029 14 0.319
phosphate containing compound metabolic process GO:0006796 108 0.319
cellular biosynthetic process GO:0044249 286 0.311
Human Zebrafish Mouse Worm Fly
cellular macromolecule metabolic process GO:0044260 391 0.306
Human Zebrafish Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.299
Human Zebrafish Mouse Worm Fly
mesenchymal cell development GO:0014031 78 0.297
Zebrafish
regulation of cell communication GO:0010646 232 0.286
Zebrafish
regulation of canonical wnt signaling pathway GO:0060828 34 0.286
biosynthetic process GO:0009058 294 0.279
Human Zebrafish Mouse Worm Fly
cellular aromatic compound metabolic process GO:0006725 295 0.273
Human Zebrafish Mouse Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.272
Human Zebrafish Mouse Worm Fly
reproductive process GO:0022414 40 0.262
Worm Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.261
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.260
Human Zebrafish Mouse Worm Fly
regulation of cellular biosynthetic process GO:0031326 245 0.258
Human Zebrafish Mouse Fly
cell part morphogenesis GO:0032990 246 0.257
neuron projection development GO:0031175 180 0.257
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.256
Human Mouse Fly
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.250
fourth ventricle development GO:0021592 8 0.243
Zebrafish
immune system process GO:0002376 241 0.242
cellular component movement GO:0006928 335 0.238
Fly
regulation of neural precursor cell proliferation GO:2000177 3 0.228
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.223
cell fate specification GO:0001708 68 0.222
Worm
organic substance biosynthetic process GO:1901576 289 0.222
Human Zebrafish Mouse Worm Fly
neuron development GO:0048666 262 0.220
cell surface receptor signaling pathway GO:0007166 325 0.217
Zebrafish Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.215
Human Mouse Fly
single organism metabolic process GO:0044710 217 0.213
brain morphogenesis GO:0048854 18 0.207
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.206
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.203
connective tissue development GO:0061448 99 0.202
wnt signaling pathway GO:0016055 80 0.201
Zebrafish
regulation of response to stimulus GO:0048583 269 0.201
Zebrafish
protein targeting to nucleus GO:0044744 3 0.201
axonogenesis GO:0007409 152 0.199
transport GO:0006810 220 0.199
anterior head development GO:0097065 2 0.197
regulation of gene expression GO:0010468 265 0.196
Human Zebrafish Mouse Fly
forebrain anterior posterior pattern specification GO:0021797 3 0.195
positive regulation of cellular process GO:0048522 201 0.195
Human Mouse Fly
neuron differentiation GO:0030182 353 0.193
Worm
embryonic eye morphogenesis GO:0048048 30 0.186
spinal cord development GO:0021510 46 0.186
Zebrafish
neuroblast proliferation GO:0007405 2 0.183
neuron projection guidance GO:0097485 86 0.180
negative regulation of gene expression GO:0010629 65 0.179
Zebrafish
macromolecule localization GO:0033036 54 0.178
Worm
multicellular organismal reproductive process GO:0048609 35 0.176
Worm Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.175
Fly
heart development GO:0007507 313 0.173
Human Mouse
embryonic heart tube development GO:0035050 133 0.171
Human Mouse
lipid storage GO:0019915 1 0.162
Worm
multicellular organism growth GO:0035264 4 0.162
embryonic camera type eye morphogenesis GO:0048596 19 0.161
regulation of rna biosynthetic process GO:2001141 213 0.158
Human Zebrafish Mouse Fly
vasculogenesis GO:0001570 41 0.153
brain development GO:0007420 293 0.152
Zebrafish
hindbrain development GO:0030902 91 0.151
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.149
mesenchyme development GO:0060485 127 0.149
Zebrafish
hair cell differentiation GO:0035315 32 0.148
determination of heart left right asymmetry GO:0061371 117 0.146
Human Mouse
dorsal ventral pattern formation GO:0009953 125 0.146
Zebrafish
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.144
dorsal ventral axis specification GO:0009950 14 0.143
positive regulation of transport GO:0051050 2 0.143
regulation of signaling GO:0023051 235 0.143
Zebrafish
locomotory behavior GO:0007626 34 0.142
retina development in camera type eye GO:0060041 146 0.142
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.142
transcription from rna polymerase ii promoter GO:0006366 80 0.142
Human Mouse Fly
optic placode formation involved in camera type eye formation GO:0046619 3 0.140
positive regulation of macromolecule metabolic process GO:0010604 93 0.140
Human Mouse Fly
regulation of phosphate metabolic process GO:0019220 43 0.140
maintenance of location GO:0051235 4 0.140
Worm
tube morphogenesis GO:0035239 349 0.140
Human Zebrafish Mouse
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.139
single organism localization GO:1902578 225 0.135
negative regulation of wnt signaling pathway GO:0030178 30 0.135
appendage development GO:0048736 80 0.135
heart looping GO:0001947 94 0.135
Human Mouse
response to fibroblast growth factor GO:0071774 22 0.135
germ cell migration GO:0008354 8 0.132
Fly
response to wounding GO:0009611 116 0.132
convergent extension GO:0060026 118 0.132
multi organism process GO:0051704 134 0.130
Worm Fly
thrombocyte differentiation GO:0002574 4 0.127
cardioblast migration GO:0003260 7 0.127
cell proliferation GO:0008283 80 0.123
Zebrafish
peripheral nervous system neuron differentiation GO:0048934 28 0.123
metencephalon development GO:0022037 27 0.123
mechanoreceptor differentiation GO:0042490 37 0.122
growth GO:0040007 174 0.122
regulation of rna metabolic process GO:0051252 224 0.120
Human Zebrafish Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.117
Human Zebrafish Mouse Worm Fly
regulation of stem cell differentiation GO:2000736 4 0.116
multi organism reproductive process GO:0044703 36 0.115
Worm Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.115
Human Mouse Fly
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.114
ectodermal placode formation GO:0060788 26 0.114
positive regulation of molecular function GO:0044093 33 0.113
neural tube patterning GO:0021532 33 0.112
stem cell differentiation GO:0048863 117 0.112
Zebrafish
neuron recognition GO:0008038 18 0.111
positive regulation of cell communication GO:0010647 56 0.111
regulation of biological quality GO:0065008 263 0.109
Worm
abducens nucleus development GO:0021742 2 0.106
regulation of glial cell differentiation GO:0045685 4 0.106
telencephalon development GO:0021537 14 0.106
stem cell development GO:0048864 82 0.105
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.104
embryonic epithelial tube formation GO:0001838 17 0.104
Zebrafish
nuclear transport GO:0051169 4 0.104
regulation of cellular protein metabolic process GO:0032268 52 0.102
phosphorylation GO:0016310 69 0.101
ear development GO:0043583 127 0.101
rna metabolic process GO:0016070 219 0.100
Human Zebrafish Mouse Worm Fly
gliogenesis GO:0042063 45 0.100
gastrulation GO:0007369 208 0.100
positive regulation of nucleic acid templated transcription GO:1903508 57 0.099
Human Mouse Fly
primary neural tube formation GO:0014020 1 0.098
single organism reproductive process GO:0044702 40 0.098
Worm Fly
ear morphogenesis GO:0042471 64 0.098
macromolecule biosynthetic process GO:0009059 227 0.097
Human Zebrafish Mouse Worm Fly
cellular response to chemical stimulus GO:0070887 157 0.097
embryonic viscerocranium morphogenesis GO:0048703 52 0.097
Zebrafish
cell migration to the midline involved in heart development GO:0003318 12 0.096
forebrain generation of neurons GO:0021872 14 0.096
optic placode formation GO:0001743 4 0.095
protein import into nucleus GO:0006606 3 0.093
single organism nuclear import GO:1902593 3 0.092
regulation of bmp signaling pathway GO:0030510 39 0.091
positive regulation of cell cycle GO:0045787 3 0.091
regulation of phosphorylation GO:0042325 26 0.090
positive regulation of signal transduction GO:0009967 56 0.090
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.090
Zebrafish
gtp metabolic process GO:0046039 4 0.089
axon guidance GO:0007411 86 0.089
regulation of multicellular organism growth GO:0040014 4 0.089
response to stress GO:0006950 263 0.089
neural tube development GO:0021915 62 0.088
Zebrafish
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.085
Human Mouse Fly
regulation of epithelial to mesenchymal transition GO:0010717 3 0.085
embryonic skeletal system development GO:0048706 97 0.085
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.085
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.084
regulation of cartilage development GO:0061035 7 0.084
regulation of transport GO:0051049 45 0.084
gene expression GO:0010467 252 0.084
Human Zebrafish Mouse Worm Fly
regulation of molecular function GO:0065009 70 0.083
regulation of phosphorus metabolic process GO:0051174 43 0.083
gall bladder development GO:0061010 1 0.083
pituitary gland development GO:0021983 16 0.082
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.082
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.082
nucleic acid templated transcription GO:0097659 181 0.081
Human Zebrafish Mouse Worm Fly
regulation of anterior head development GO:2000742 2 0.081
cellular protein modification process GO:0006464 100 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.080
Human Mouse Fly
embryonic camera type eye formation GO:0060900 10 0.080
regulation of binding GO:0051098 3 0.077
nucleobase containing small molecule metabolic process GO:0055086 32 0.077
embryo development ending in birth or egg hatching GO:0009792 271 0.076
Zebrafish
response to chemical GO:0042221 320 0.075
protein localization to nucleus GO:0034504 3 0.075
positive regulation of neural precursor cell proliferation GO:2000179 1 0.074
stem cell proliferation GO:0072089 4 0.074
nucleocytoplasmic transport GO:0006913 4 0.073
appendage morphogenesis GO:0035107 56 0.073
cellular component assembly involved in morphogenesis GO:0010927 107 0.073
rna biosynthetic process GO:0032774 181 0.072
Human Zebrafish Mouse Worm Fly
epithelial tube formation GO:0072175 19 0.072
Zebrafish
otic vesicle morphogenesis GO:0071600 34 0.071
endodermal cell fate determination GO:0007493 2 0.071
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.069
peripheral nervous system development GO:0007422 55 0.069
establishment of localization GO:0051234 244 0.069
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.069
regulation of cell migration GO:0030334 40 0.069
cartilage development GO:0051216 96 0.069
otic placode formation GO:0043049 23 0.068
neuron fate specification GO:0048665 20 0.068
Worm
positive regulation of jun kinase activity GO:0043507 2 0.068
pancreas development GO:0031016 84 0.068
Human
regulation of wnt signaling pathway GO:0030111 53 0.067
angiogenesis GO:0001525 158 0.067
extracellular fibril organization GO:0043206 1 0.065
dopaminergic neuron differentiation GO:0071542 14 0.065
peptide transport GO:0015833 1 0.065
oligodendrocyte differentiation GO:0048709 23 0.065
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.065
regulation of locomotion GO:0040012 55 0.065
hepaticobiliary system development GO:0061008 98 0.065
Human
midbrain hindbrain boundary development GO:0030917 23 0.064
positive regulation of cellular component biogenesis GO:0044089 3 0.064
bmp signaling pathway GO:0030509 52 0.063
neuron projection morphogenesis GO:0048812 161 0.063
epithelial tube morphogenesis GO:0060562 148 0.063
Human Zebrafish Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.062
regulation of cell proliferation GO:0042127 37 0.061
Zebrafish
immune system development GO:0002520 191 0.061
regulation of endodermal cell fate specification GO:0042663 15 0.061
organelle organization GO:0006996 227 0.060
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.060
adult behavior GO:0030534 2 0.059
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.059
otolith development GO:0048840 32 0.059
otic vesicle development GO:0071599 42 0.059
auditory receptor cell fate commitment GO:0009912 4 0.058
embryonic limb morphogenesis GO:0030326 2 0.057
renal system development GO:0072001 94 0.055
mammillary body development GO:0021767 4 0.055
positive regulation of developmental process GO:0051094 50 0.055
chemotaxis GO:0006935 104 0.055
hematopoietic or lymphoid organ development GO:0048534 191 0.054
hepatic duct development GO:0061011 2 0.054
negative regulation of signal transduction GO:0009968 94 0.053
positive regulation of transcription dna templated GO:0045893 57 0.053
Human Mouse Fly
inner ear morphogenesis GO:0042472 63 0.053
tube closure GO:0060606 1 0.053
response to organic substance GO:0010033 153 0.052
behavior GO:0007610 74 0.052
Worm
protein import GO:0017038 3 0.052
inner ear receptor cell differentiation GO:0060113 29 0.052
positive regulation of rna biosynthetic process GO:1902680 57 0.052
Human Mouse Fly
mitotic cell cycle process GO:1903047 48 0.052
heart morphogenesis GO:0003007 156 0.052
Human Mouse
signal transduction GO:0007165 455 0.052
Zebrafish Fly
positive regulation of signaling GO:0023056 56 0.052
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.051
regulation of cell motility GO:2000145 46 0.051
protein modification process GO:0036211 100 0.051
chordate embryonic development GO:0043009 271 0.051
Zebrafish
gtp catabolic process GO:0006184 2 0.051
negative regulation of cellular biosynthetic process GO:0031327 55 0.050
Zebrafish
neural tube formation GO:0001841 16 0.050
Zebrafish
localization of cell GO:0051674 244 0.050
Fly
cell growth GO:0016049 57 0.050
ameboidal type cell migration GO:0001667 143 0.050
fin morphogenesis GO:0033334 53 0.050
negative regulation of rna metabolic process GO:0051253 48 0.050
Zebrafish
fin development GO:0033333 77 0.050
positive regulation of gene expression GO:0010628 71 0.049
Human Mouse Fly
regulation of protein metabolic process GO:0051246 56 0.049
epithelium regeneration GO:1990399 14 0.049
neural plate regionalization GO:0060897 10 0.048
determination of pancreatic left right asymmetry GO:0035469 11 0.048
Human
neuroepithelial cell differentiation GO:0060563 26 0.047
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.047
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.047
Fly
cell cycle GO:0007049 93 0.047
negative regulation of metabolic process GO:0009892 86 0.047
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.046
fin regeneration GO:0031101 51 0.046
amine metabolic process GO:0009308 2 0.046
pectoral fin morphogenesis GO:0035138 29 0.046
kupffer s vesicle development GO:0070121 50 0.046
regionalization GO:0003002 274 0.045
epiboly GO:0090504 41 0.045
negative regulation of phosphorus metabolic process GO:0010563 13 0.044
single organism organelle organization GO:1902589 199 0.044
oxoacid metabolic process GO:0043436 31 0.044
protein localization GO:0008104 40 0.044
regulation of immune system process GO:0002682 34 0.043
positive regulation of map kinase activity GO:0043406 3 0.043
cellular localization GO:0051641 97 0.042
negative regulation of rna biosynthetic process GO:1902679 45 0.041
Zebrafish
inner ear receptor cell development GO:0060119 20 0.041
negative regulation of phosphate metabolic process GO:0045936 13 0.041
negative regulation of biological process GO:0048519 304 0.041
Zebrafish
hepatocyte proliferation GO:0072574 2 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
regulation of protein import into nucleus GO:0042306 2 0.041
positive regulation of cell division GO:0051781 2 0.040
regulation of erk1 and erk2 cascade GO:0070372 4 0.040
non canonical wnt signaling pathway GO:0035567 13 0.040
spinal cord anterior posterior patterning GO:0021512 1 0.040
response to external stimulus GO:0009605 264 0.039
embryonic skeletal system morphogenesis GO:0048704 93 0.039
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.039
glial cell differentiation GO:0010001 42 0.039
skin development GO:0043588 54 0.039
skeletal system morphogenesis GO:0048705 102 0.038
Zebrafish
hemopoiesis GO:0030097 183 0.038
intracellular signal transduction GO:0035556 85 0.037
single organism biosynthetic process GO:0044711 71 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
cell migration GO:0016477 237 0.036
Fly
locomotion GO:0040011 313 0.036
Worm Fly
cellular response to prostaglandin stimulus GO:0071379 3 0.036
macromolecule modification GO:0043412 111 0.035
regulation of gtp catabolic process GO:0033124 2 0.035
cellular response to organic substance GO:0071310 105 0.035
organonitrogen compound metabolic process GO:1901564 74 0.035
wound healing GO:0042060 90 0.034
regulation of circadian rhythm GO:0042752 4 0.034
cellular response to stress GO:0033554 62 0.034
muscle structure development GO:0061061 196 0.034
regulation of stem cell proliferation GO:0072091 2 0.033
cerebellum development GO:0021549 17 0.033
developmental growth GO:0048589 166 0.033
proximal distal pattern formation GO:0009954 1 0.032
mesodermal cell differentiation GO:0048333 21 0.032
stem cell maintenance GO:0019827 4 0.032
positive regulation of catabolic process GO:0009896 4 0.032
mediolateral intercalation GO:0060031 3 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
Human Zebrafish Mouse Fly
regulation of cellular amine metabolic process GO:0033238 0 0.032
protein metabolic process GO:0019538 183 0.032
guanosine containing compound metabolic process GO:1901068 4 0.032
epidermis development GO:0008544 48 0.031
endoderm development GO:0007492 49 0.031
central nervous system projection neuron axonogenesis GO:0021952 15 0.031
regulation of protein localization to nucleus GO:1900180 2 0.031
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.031
Zebrafish
olfactory placode development GO:0071698 12 0.031
regulation of cellular component movement GO:0051270 55 0.031
nuclear import GO:0051170 3 0.031
urogenital system development GO:0001655 97 0.031
cell differentiation in spinal cord GO:0021515 40 0.031
epithelial to mesenchymal transition GO:0001837 21 0.030
positive regulation of rna metabolic process GO:0051254 59 0.030
Human Mouse Fly
somatic stem cell maintenance GO:0035019 1 0.030
cell migration involved in heart formation GO:0060974 10 0.030
embryonic appendage morphogenesis GO:0035113 30 0.029
protein phosphorylation GO:0006468 47 0.029
endodermal cell differentiation GO:0035987 19 0.029
anterior posterior axis specification GO:0009948 20 0.029
regulation of protein phosphorylation GO:0001932 18 0.029
positive regulation of biosynthetic process GO:0009891 68 0.028
Human Mouse Fly
cellular protein metabolic process GO:0044267 129 0.028
forebrain dorsal ventral pattern formation GO:0021798 1 0.028
spinal cord motor neuron differentiation GO:0021522 26 0.028
endocrine pancreas development GO:0031018 27 0.028
anterior commissure morphogenesis GO:0021960 3 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.027
convergent extension involved in gastrulation GO:0060027 71 0.027
multicellular organism reproduction GO:0032504 35 0.027
Worm Fly
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.027
nephron morphogenesis GO:0072028 2 0.027
negative regulation of cellular metabolic process GO:0031324 77 0.027
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.027
death GO:0016265 121 0.027
pigmentation GO:0043473 85 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
neural plate anterior posterior regionalization GO:0021999 8 0.027
regulation of cell fate commitment GO:0010453 22 0.027
regulation of localization GO:0032879 104 0.027
oligodendrocyte cell fate specification GO:0021778 4 0.027
positive regulation of response to stimulus GO:0048584 80 0.027
swim bladder development GO:0048794 19 0.027
regulation of protein targeting GO:1903533 2 0.027
cell migration involved in heart development GO:0060973 22 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.026
regulation of catalytic activity GO:0050790 55 0.026
cell cell signaling GO:0007267 52 0.025
regulation of gliogenesis GO:0014013 6 0.025
embryonic pectoral fin morphogenesis GO:0035118 24 0.025
sex differentiation GO:0007548 5 0.025
Worm
myeloid cell development GO:0061515 32 0.025
somitogenesis GO:0001756 87 0.025
neural crest cell fate specification GO:0014036 5 0.025
regulation of apoptotic process GO:0042981 98 0.025
regulation of cell activation GO:0050865 1 0.025
cell motility GO:0048870 244 0.024
Fly
positive regulation of secretion by cell GO:1903532 1 0.024
optomotor response GO:0071632 1 0.024
sensory epithelium regeneration GO:0070654 14 0.024
diencephalon morphogenesis GO:0048852 5 0.024
regulation of transferase activity GO:0051338 16 0.024
organic acid metabolic process GO:0006082 31 0.024
regulation of cellular response to growth factor stimulus GO:0090287 35 0.023
negative regulation of gliogenesis GO:0014014 1 0.023
response to radiation GO:0009314 51 0.023
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.023
regulation of cell cycle GO:0051726 52 0.023
small molecule metabolic process GO:0044281 77 0.023
regulation of inner ear receptor cell differentiation GO:2000980 1 0.023
negative regulation of mitosis GO:0045839 3 0.023
regulation of catenin import into nucleus GO:0035412 2 0.023
positive regulation of secretion GO:0051047 1 0.023
negative regulation of stem cell differentiation GO:2000737 2 0.023
cellular amine metabolic process GO:0044106 2 0.023
positive regulation of stem cell proliferation GO:2000648 1 0.022
lateral inhibition GO:0046331 1 0.022
rostrocaudal neural tube patterning GO:0021903 29 0.022
neurological system process GO:0050877 62 0.022
unidimensional cell growth GO:0009826 5 0.022
eye photoreceptor cell development GO:0042462 30 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.022
Human Mouse Fly
hypothalamus development GO:0021854 14 0.022
blood vessel morphogenesis GO:0048514 216 0.022
endodermal cell fate commitment GO:0001711 18 0.022
cell fate commitment GO:0045165 99 0.022
Worm
cytoskeleton organization GO:0007010 96 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.021
neuron fate determination GO:0048664 2 0.021
chondrocyte differentiation GO:0002062 7 0.021
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
mitotic cell cycle GO:0000278 64 0.021
somite development GO:0061053 96 0.021
taxis GO:0042330 109 0.021
gland development GO:0048732 143 0.021
Human
actin cytoskeleton organization GO:0030036 63 0.021
auditory receptor cell fate determination GO:0042668 2 0.021
erk1 and erk2 cascade GO:0070371 4 0.021

zic3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.136
Human
congenital nervous system abnormality DOID:2490 0 0.105
sensory system disease DOID:0050155 0 0.025
disease of anatomical entity DOID:7 0 0.025
eye and adnexa disease DOID:1492 0 0.025
nervous system disease DOID:863 0 0.025