Danio rerio

23 known processes

col27a1a

collagen, type XXVII, alpha 1a

(Aliases: sb:cb221)

col27a1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notochord development GO:0030903 54 0.925
embryonic organ development GO:0048568 381 0.912
digestive system development GO:0055123 289 0.830
embryonic organ morphogenesis GO:0048562 274 0.726
positive regulation of rna metabolic process GO:0051254 59 0.630
notochord morphogenesis GO:0048570 17 0.528
chordate embryonic development GO:0043009 271 0.515
regulation of establishment of protein localization GO:0070201 4 0.481
multicellular organismal metabolic process GO:0044236 2 0.452
rna biosynthetic process GO:0032774 181 0.442
cilium assembly GO:0042384 58 0.426
cell migration GO:0016477 237 0.413
digestive tract development GO:0048565 265 0.409
ameboidal type cell migration GO:0001667 143 0.406
biosynthetic process GO:0009058 294 0.406
regulation of intracellular protein transport GO:0033157 3 0.398
regulation of cellular metabolic process GO:0031323 320 0.373
protein localization to nucleus GO:0034504 3 0.368
regulation of metabolic process GO:0019222 359 0.365
transcription dna templated GO:0006351 181 0.362
cell surface receptor signaling pathway GO:0007166 325 0.358
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.356
regulation of protein targeting GO:1903533 2 0.348
establishment of protein localization to organelle GO:0072594 4 0.346
organic cyclic compound biosynthetic process GO:1901362 223 0.329
protein targeting to nucleus GO:0044744 3 0.325
cellular nitrogen compound biosynthetic process GO:0044271 218 0.323
digestive tract morphogenesis GO:0048546 231 0.309
sensory organ development GO:0007423 393 0.303
protein import into nucleus GO:0006606 3 0.294
skeletal system development GO:0001501 181 0.294
multicellular organism growth GO:0035264 4 0.286
regulation of macromolecule biosynthetic process GO:0010556 225 0.281
embryonic skeletal system morphogenesis GO:0048704 93 0.241
regulation of protein transport GO:0051223 3 0.238
regionalization GO:0003002 274 0.237
gene expression GO:0010467 252 0.233
bone morphogenesis GO:0060349 11 0.231
Mouse
specification of symmetry GO:0009799 204 0.229
bmp signaling pathway GO:0030509 52 0.224
single organism nuclear import GO:1902593 3 0.224
negative regulation of cell communication GO:0010648 96 0.221
response to external stimulus GO:0009605 264 0.215
signal transduction GO:0007165 455 0.209
nucleocytoplasmic transport GO:0006913 4 0.209
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.199
regulation of transcription dna templated GO:0006355 213 0.196
gastrulation GO:0007369 208 0.195
response to wounding GO:0009611 116 0.192
larval development GO:0002164 2 0.191
determination of bilateral symmetry GO:0009855 204 0.189
regulation of protein localization to nucleus GO:1900180 2 0.180
single organism localization GO:1902578 225 0.180
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.179
regulation of nucleic acid templated transcription GO:1903506 213 0.178
aging GO:0007568 2 0.174
regulation of rna biosynthetic process GO:2001141 213 0.168
sensory organ morphogenesis GO:0090596 200 0.162
response to abiotic stimulus GO:0009628 122 0.156
nuclear transport GO:0051169 4 0.155
cellular macromolecule metabolic process GO:0044260 391 0.154
embryonic skeletal system development GO:0048706 97 0.153
extracellular matrix organization GO:0030198 27 0.152
Mouse
chondrocyte development GO:0002063 4 0.151
Mouse
nucleic acid templated transcription GO:0097659 181 0.147
positive regulation of transport GO:0051050 2 0.146
macromolecule biosynthetic process GO:0009059 227 0.142
collagen metabolic process GO:0032963 2 0.138
cell projection assembly GO:0030031 64 0.136
regulation of protein import into nucleus GO:0042306 2 0.136
regulation of nucleocytoplasmic transport GO:0046822 2 0.135
transcription from rna polymerase ii promoter GO:0006366 80 0.135
tube morphogenesis GO:0035239 349 0.132
cellular macromolecule biosynthetic process GO:0034645 224 0.131
response to stress GO:0006950 263 0.131
nucleobase containing compound biosynthetic process GO:0034654 205 0.130
regulation of response to stimulus GO:0048583 269 0.129
cellular biosynthetic process GO:0044249 286 0.128
extracellular structure organization GO:0043062 27 0.125
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.125
regulation of cellular biosynthetic process GO:0031326 245 0.118
regulation of cytoplasmic transport GO:1903649 4 0.116
cell aggregation GO:0098743 3 0.113
nuclear import GO:0051170 3 0.109
protein import GO:0017038 3 0.107
negative regulation of biological process GO:0048519 304 0.106
regulation of bmp signaling pathway GO:0030510 39 0.104
cell migration involved in gastrulation GO:0042074 79 0.100
negative regulation of bmp signaling pathway GO:0030514 13 0.097
inner ear development GO:0048839 126 0.097
regulation of biosynthetic process GO:0009889 250 0.096
determination of heart left right asymmetry GO:0061371 117 0.096
glycoprotein metabolic process GO:0009100 23 0.094
skin development GO:0043588 54 0.091
positive regulation of map kinase activity GO:0043406 3 0.091
cellular component movement GO:0006928 335 0.089
collagen biosynthetic process GO:0032964 2 0.087
regulation of localization GO:0032879 104 0.085
nitrogen compound metabolic process GO:0006807 319 0.085
negative regulation of cytoplasmic transport GO:1903650 2 0.081
skeletal system morphogenesis GO:0048705 102 0.080
Mouse
determination of left right symmetry GO:0007368 179 0.078
regulation of multicellular organism growth GO:0040014 4 0.076
regulation of signaling GO:0023051 235 0.076
cell proliferation in forebrain GO:0021846 3 0.075
cellular localization GO:0051641 97 0.075
muscle structure development GO:0061061 196 0.075
multicellular organismal macromolecule metabolic process GO:0044259 2 0.073
proteoglycan metabolic process GO:0006029 14 0.071
cartilage development GO:0051216 96 0.071
Mouse
organic substance biosynthetic process GO:1901576 289 0.071
positive regulation of cell adhesion GO:0045785 1 0.071
nucleobase containing compound metabolic process GO:0006139 274 0.071
response to biotic stimulus GO:0009607 97 0.070
localization of cell GO:0051674 244 0.069
endodermal cell differentiation GO:0035987 19 0.069
ossification GO:0001503 23 0.068
regulation of cell communication GO:0010646 232 0.065
developmental growth GO:0048589 166 0.064
Mouse
wnt signaling pathway GO:0016055 80 0.064
response to bacterium GO:0009617 58 0.063
motor neuron axon guidance GO:0008045 23 0.063
cellular aromatic compound metabolic process GO:0006725 295 0.063
positive regulation of catabolic process GO:0009896 4 0.062
regulation of gene expression GO:0010468 265 0.062
dorsal ventral pattern formation GO:0009953 125 0.061
embryonic cranial skeleton morphogenesis GO:0048701 90 0.061
cartilage condensation GO:0001502 3 0.059
gland development GO:0048732 143 0.058
neuron development GO:0048666 262 0.057
locomotion GO:0040011 313 0.057
fin morphogenesis GO:0033334 53 0.056
neural crest cell migration GO:0001755 42 0.056
angiogenesis GO:0001525 158 0.056
nitric oxide metabolic process GO:0046209 2 0.054
regulation of cell migration GO:0030334 40 0.054
negative regulation of protein localization to nucleus GO:1900181 2 0.054
regulation of cellular component movement GO:0051270 55 0.054
morphogenesis of an epithelium GO:0002009 333 0.054
cellular response to organic substance GO:0071310 105 0.054
response to monosaccharide GO:0034284 3 0.053
otic vesicle development GO:0071599 42 0.053
small molecule metabolic process GO:0044281 77 0.052
cellular component assembly GO:0022607 170 0.051
establishment of localization in cell GO:0051649 77 0.051
organic cyclic compound metabolic process GO:1901360 301 0.051
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.050
regeneration GO:0031099 91 0.050
epiboly GO:0090504 41 0.050
positive regulation of protein kinase b signaling GO:0051897 1 0.049
cellular response to chemical stimulus GO:0070887 157 0.049
response to chemical GO:0042221 320 0.048
embryonic viscerocranium morphogenesis GO:0048703 52 0.048
single organism transport GO:0044765 206 0.047
positive regulation of signaling GO:0023056 56 0.047
tissue homeostasis GO:0001894 25 0.046
response to organic substance GO:0010033 153 0.046
heterocycle metabolic process GO:0046483 290 0.045
wound healing GO:0042060 90 0.045
medial fin morphogenesis GO:0035141 14 0.043
response to other organism GO:0051707 97 0.042
fin development GO:0033333 77 0.041
negative regulation of response to stimulus GO:0048585 104 0.041
positive regulation of cellular process GO:0048522 201 0.041
regulation of signal transduction GO:0009966 225 0.040
epithelial tube morphogenesis GO:0060562 148 0.040
collagen fibril organization GO:0030199 1 0.040
positive regulation of cell communication GO:0010647 56 0.040
inner ear morphogenesis GO:0042472 63 0.040
cell motility GO:0048870 244 0.039
positive regulation of response to stimulus GO:0048584 80 0.039
cell proliferation involved in heart morphogenesis GO:0061323 2 0.039
response to vitamin GO:0033273 3 0.039
response to decreased oxygen levels GO:0036293 25 0.039
positive regulation of transcription dna templated GO:0045893 57 0.039
cilium morphogenesis GO:0060271 85 0.039
negative regulation of cellular process GO:0048523 283 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
positive regulation of rna biosynthetic process GO:1902680 57 0.038
eye morphogenesis GO:0048592 144 0.038
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.038
rna metabolic process GO:0016070 219 0.037
eye development GO:0001654 277 0.037
bone development GO:0060348 14 0.037
Mouse
response to radiation GO:0009314 51 0.036
glial cell migration GO:0008347 3 0.036
cell substrate adhesion GO:0031589 4 0.036
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.035
embryonic heart tube morphogenesis GO:0003143 108 0.035
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.035
negative regulation of endodermal cell differentiation GO:1903225 8 0.034
central nervous system neuron development GO:0021954 29 0.034
regulation of cell motility GO:2000145 46 0.034
negative regulation of epithelial cell proliferation GO:0050680 1 0.033
positive regulation of biological process GO:0048518 253 0.033
negative regulation of intracellular transport GO:0032387 3 0.033
connective tissue development GO:0061448 99 0.033
Mouse
mesenchymal cell development GO:0014031 78 0.032
regulation of immune system process GO:0002682 34 0.032
macromolecule localization GO:0033036 54 0.032
lateral inhibition GO:0046331 1 0.031
cell proliferation GO:0008283 80 0.031
negative regulation of protein transport GO:0051224 3 0.031
embryonic heart tube development GO:0035050 133 0.031
cell part morphogenesis GO:0032990 246 0.031
oxoacid metabolic process GO:0043436 31 0.031
negative regulation of signal transduction GO:0009968 94 0.031
positive regulation of metabolic process GO:0009893 108 0.031
heterocycle biosynthetic process GO:0018130 215 0.030
single organism intracellular transport GO:1902582 25 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
positive regulation of carbohydrate metabolic process GO:0045913 1 0.030
regulation of rna metabolic process GO:0051252 224 0.030
cell morphogenesis GO:0000902 289 0.029
regulation of locomotion GO:0040012 55 0.029
cellular protein catabolic process GO:0044257 4 0.029
cell projection organization GO:0030030 284 0.029
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.029
regulation of cell proliferation GO:0042127 37 0.029
transport GO:0006810 220 0.029
bmp signaling pathway involved in heart jogging GO:0003303 14 0.028
immune system process GO:0002376 241 0.028
heart valve morphogenesis GO:0003179 8 0.028
single organism cellular localization GO:1902580 46 0.028
notochord cell differentiation GO:0060034 18 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
nucleic acid metabolic process GO:0090304 244 0.027
positive regulation of cellular component organization GO:0051130 13 0.027
convergent extension GO:0060026 118 0.027
establishment of localization GO:0051234 244 0.027
mesenchymal cell differentiation GO:0048762 87 0.027
regulation of epithelial cell proliferation GO:0050678 3 0.027
axon development GO:0061564 166 0.026
phosphorus metabolic process GO:0006793 109 0.026
heart morphogenesis GO:0003007 156 0.026
regulation of protein binding GO:0043393 3 0.026
stem cell development GO:0048864 82 0.026
muscle attachment GO:0016203 9 0.026
photoreceptor cell fate commitment GO:0046552 1 0.025
endoderm development GO:0007492 49 0.025
determination of dorsal ventral asymmetry GO:0048262 34 0.025
mesodermal cell fate specification GO:0007501 12 0.025
organic acid metabolic process GO:0006082 31 0.025
neuron projection development GO:0031175 180 0.025
cell cell signaling involved in cell fate commitment GO:0045168 12 0.025
phosphorylation GO:0016310 69 0.025
negative regulation of leukocyte differentiation GO:1902106 1 0.024
regulation of protein catabolic process GO:0042176 1 0.024
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.024
morphogenesis of an epithelial sheet GO:0002011 49 0.024
stem cell differentiation GO:0048863 117 0.024
response to hexose GO:0009746 3 0.023
regulation of wnt signaling pathway GO:0030111 53 0.023
activation of mapk activity GO:0000187 3 0.023
optic placode formation GO:0001743 4 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
appendage morphogenesis GO:0035107 56 0.023
basement membrane assembly GO:0070831 3 0.023
cellular component biogenesis GO:0044085 178 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
negative regulation of intracellular protein transport GO:0090317 3 0.022
cellular component disassembly GO:0022411 1 0.022
negative regulation of oocyte development GO:0060283 2 0.022
heart looping GO:0001947 94 0.022
regulation of cell activation GO:0050865 1 0.022
intracellular transport GO:0046907 32 0.021
atrial ventricular junction remodeling GO:0003294 2 0.021
oocyte maturation GO:0001556 4 0.021
convergent extension involved in gastrulation GO:0060027 71 0.021
embryonic digestive tract development GO:0048566 4 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
immune system development GO:0002520 191 0.021
positive regulation of oocyte development GO:0060282 1 0.021
ion homeostasis GO:0050801 41 0.021
cell matrix adhesion GO:0007160 4 0.021
coagulation GO:0050817 13 0.020
regulation of erk1 and erk2 cascade GO:0070372 4 0.020
ear morphogenesis GO:0042471 64 0.020
endodermal digestive tract morphogenesis GO:0061031 2 0.020
regulation of developmental process GO:0050793 247 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
brain development GO:0007420 293 0.020
carbohydrate derivative metabolic process GO:1901135 61 0.020
central nervous system development GO:0007417 387 0.020
tissue regeneration GO:0042246 74 0.019
response to oxygen levels GO:0070482 25 0.019
endothelial cell morphogenesis GO:0001886 1 0.019
heart valve formation GO:0003188 4 0.019
chemotaxis GO:0006935 104 0.019
response to light stimulus GO:0009416 46 0.019
mesodermal cell migration GO:0008078 12 0.018
heart valve development GO:0003170 14 0.018
canonical wnt signaling pathway GO:0060070 48 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
neuron projection guidance GO:0097485 86 0.017
kidney development GO:0001822 92 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of stem cell differentiation GO:2000736 4 0.016
positive regulation of cell activation GO:0050867 1 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of organ morphogenesis GO:2000027 35 0.016
intramembranous ossification GO:0001957 3 0.016
generation of neurons GO:0048699 385 0.016
endoderm formation GO:0001706 29 0.016
protein metabolic process GO:0019538 183 0.016
cell projection morphogenesis GO:0048858 244 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
cranial suture morphogenesis GO:0060363 1 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
iron ion homeostasis GO:0055072 4 0.015
regulation of epithelial to mesenchymal transition GO:0010717 3 0.015
mesoderm development GO:0007498 88 0.015
cognition GO:0050890 1 0.015
cardiac endothelial cell differentiation GO:0003348 5 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
glandular epithelial cell differentiation GO:0002067 9 0.015
protein localization to plasma membrane GO:0072659 1 0.015
appendage development GO:0048736 80 0.015
fin regeneration GO:0031101 51 0.015
caudal fin morphogenesis GO:0035143 7 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
endochondral bone morphogenesis GO:0060350 8 0.014
Mouse
embryonic camera type eye morphogenesis GO:0048596 19 0.014
otic vesicle morphogenesis GO:0071600 34 0.014
detection of stimulus involved in sensory perception GO:0050906 21 0.014
convergent extension involved in axis elongation GO:0060028 26 0.014
response to amino acid GO:0043200 2 0.014
pancreas development GO:0031016 84 0.014
axon regeneration GO:0031103 14 0.014
amine metabolic process GO:0009308 2 0.014
limb bud formation GO:0060174 2 0.014
maintenance of location GO:0051235 4 0.014
direct ossification GO:0036072 3 0.014
hepaticobiliary system development GO:0061008 98 0.014
embryonic eye morphogenesis GO:0048048 30 0.014
regulation of cartilage development GO:0061035 7 0.013
multicellular organismal homeostasis GO:0048871 29 0.013
regulation of binding GO:0051098 3 0.013
central nervous system projection neuron axonogenesis GO:0021952 15 0.013
divalent inorganic anion homeostasis GO:0072505 5 0.013
meiotic cell cycle process GO:1903046 3 0.013
heart jogging GO:0003146 40 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
phagocytosis GO:0006909 3 0.013
regulation of primary metabolic process GO:0080090 311 0.013
protein processing GO:0016485 12 0.013
response to nutrient GO:0007584 3 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
ear development GO:0043583 127 0.013
neuroblast differentiation GO:0014016 1 0.013
craniofacial suture morphogenesis GO:0097094 2 0.012
neural crest cell development GO:0014032 62 0.012
formation of primary germ layer GO:0001704 62 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
detection of external stimulus GO:0009581 24 0.012
stem cell division GO:0017145 1 0.012
foregut morphogenesis GO:0007440 4 0.012
gland morphogenesis GO:0022612 13 0.012
endocardium morphogenesis GO:0003160 4 0.012
epithelial cell development GO:0002064 42 0.012
blood vessel development GO:0001568 246 0.012
cellular protein localization GO:0034613 20 0.012
neural crest cell differentiation GO:0014033 72 0.012
embryonic hemopoiesis GO:0035162 53 0.012
mesenchyme development GO:0060485 127 0.012
positive regulation of neurogenesis GO:0050769 24 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
response to molecule of bacterial origin GO:0002237 14 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
positive regulation of cell motility GO:2000147 11 0.011
regulation of biological quality GO:0065008 263 0.011
growth plate cartilage development GO:0003417 2 0.011
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.011
growth GO:0040007 174 0.011
Mouse
single organism organelle organization GO:1902589 199 0.011
anterior posterior pattern specification GO:0009952 152 0.011
response to lipid GO:0033993 60 0.011
negative regulation of signaling GO:0023057 96 0.011
single organism metabolic process GO:0044710 217 0.011
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
establishment of protein localization GO:0045184 14 0.011
spinal cord radial glial cell differentiation GO:0021531 2 0.011
hard palate development GO:0060022 4 0.011
negative regulation of endodermal cell fate specification GO:0042664 8 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
neurological system process GO:0050877 62 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
organic substance transport GO:0071702 58 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
rho protein signal transduction GO:0007266 5 0.011
protein secretion GO:0009306 1 0.011
heart development GO:0007507 313 0.011
epithelial cell proliferation GO:0050673 17 0.011
optic placode formation involved in camera type eye formation GO:0046619 3 0.011
positive regulation of cell cycle GO:0045787 3 0.011
positive regulation of wound healing GO:0090303 1 0.010
defense response GO:0006952 47 0.010
cellular ketone metabolic process GO:0042180 11 0.010
cellular macromolecule localization GO:0070727 21 0.010
regulation of transport GO:0051049 45 0.010
basement membrane organization GO:0071711 5 0.010
signal transduction by phosphorylation GO:0023014 18 0.010

col27a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.108
bone development disease DOID:0080006 0 0.073
bone disease DOID:0080001 0 0.073
musculoskeletal system disease DOID:17 0 0.073
connective tissue disease DOID:65 0 0.073
nervous system disease DOID:863 0 0.036
osteochondrodysplasia DOID:2256 0 0.034
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
retinal disease DOID:5679 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013