Danio rerio

0 known processes

ctssb.2

cathepsin S, b.2

(Aliases: wu:fj84d06,zgc:112489,zgc:111950)

ctssb.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 241 0.171
Human
superoxide metabolic process GO:0006801 2 0.144
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.086
Human Mouse
cellular protein catabolic process GO:0044257 4 0.083
Human Mouse
response to chemical GO:0042221 320 0.083
Human
regulation of cell activation GO:0050865 1 0.077
regulation of primary metabolic process GO:0080090 311 0.073
cellular response to chemical stimulus GO:0070887 157 0.066
Human
regulation of response to stimulus GO:0048583 269 0.061
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.060
collagen metabolic process GO:0032963 2 0.059
Human
protein metabolic process GO:0019538 183 0.056
Human Mouse
amine metabolic process GO:0009308 2 0.055
response to external stimulus GO:0009605 264 0.054
Zebrafish Mouse
larval development GO:0002164 2 0.053
adaptive immune response GO:0002250 5 0.052
Human
medulla oblongata development GO:0021550 4 0.052
regulation of immune system process GO:0002682 34 0.052
multicellular organismal metabolic process GO:0044236 2 0.050
Human
response to organic substance GO:0010033 153 0.045
Human
signal transduction in absence of ligand GO:0038034 1 0.045
reactive oxygen species metabolic process GO:0072593 6 0.042
positive regulation of catabolic process GO:0009896 4 0.042
negative regulation of cellular process GO:0048523 283 0.041
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.040
regulation of response to oxidative stress GO:1902882 2 0.039
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
granulocyte migration GO:0097530 11 0.037
hydrogen peroxide metabolic process GO:0042743 2 0.037
positive regulation of response to stimulus GO:0048584 80 0.036
Mouse
regulation of signal transduction GO:0009966 225 0.036
positive regulation of cellular extravasation GO:0002693 1 0.034
regulation of blood vessel size GO:0050880 2 0.034
regulation of protein catabolic process GO:0042176 1 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
small molecule metabolic process GO:0044281 77 0.033
camera type eye development GO:0043010 222 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.032
nuclear transport GO:0051169 4 0.032
single organism metabolic process GO:0044710 217 0.031
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
multicellular organismal macromolecule metabolic process GO:0044259 2 0.029
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.029
death GO:0016265 121 0.029
biological adhesion GO:0022610 40 0.029
multicellular organism growth GO:0035264 4 0.029
homeostasis of number of cells within a tissue GO:0048873 4 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
establishment of protein localization to organelle GO:0072594 4 0.027
inflammatory response GO:0006954 8 0.027
Mouse
regeneration GO:0031099 91 0.027
regulation of metabolic process GO:0019222 359 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
phagosome maturation GO:0090382 1 0.027
signal transduction GO:0007165 455 0.026
muscle tissue development GO:0060537 110 0.025
regulation of multicellular organism growth GO:0040014 4 0.025
rna metabolic process GO:0016070 219 0.025
interspecies interaction between organisms GO:0044419 4 0.025
regulation of cell motility GO:2000145 46 0.025
negative regulation of biological process GO:0048519 304 0.025
tissue regeneration GO:0042246 74 0.025
positive regulation of transport GO:0051050 2 0.024
protein polymerization GO:0051258 4 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
sensory organ development GO:0007423 393 0.023
innate immune response GO:0045087 13 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
cellular macromolecule metabolic process GO:0044260 391 0.022
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.021
generation of neurons GO:0048699 385 0.021
regulation of cytokine production GO:0001817 3 0.021
regulation of signaling GO:0023051 235 0.021
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
nucleic acid transport GO:0050657 2 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
cellular protein metabolic process GO:0044267 129 0.021
Human Mouse
tissue remodeling GO:0048771 4 0.020
myeloid leukocyte migration GO:0097529 12 0.020
oxoacid metabolic process GO:0043436 31 0.020
cellular component movement GO:0006928 335 0.020
regulation of inflammatory response GO:0050727 2 0.020
Mouse
regulation of programmed cell death GO:0043067 101 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
cellular ketone metabolic process GO:0042180 11 0.020
regulation of production of molecular mediator of immune response GO:0002700 1 0.020
negative regulation of protein kinase activity GO:0006469 4 0.019
cellular component assembly GO:0022607 170 0.019
carbohydrate derivative biosynthetic process GO:1901137 43 0.019
regulation of tube size GO:0035150 2 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.018
regulation of neutrophil migration GO:1902622 6 0.018
response to external biotic stimulus GO:0043207 97 0.018
localization of cell GO:0051674 244 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
regulation of cellular component organization GO:0051128 86 0.018
positive regulation of cellular process GO:0048522 201 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
positive regulation of neutrophil extravasation GO:2000391 1 0.017
angiogenesis GO:0001525 158 0.017
response to stress GO:0006950 263 0.017
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
protein secretion GO:0009306 1 0.017
leukocyte mediated cytotoxicity GO:0001909 1 0.017
lateral line development GO:0048882 66 0.016
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
organelle fusion GO:0048284 3 0.016
regulation of defense response GO:0031347 14 0.016
Mouse
brain development GO:0007420 293 0.016
regulation of apoptotic process GO:0042981 98 0.016
positive regulation of cell communication GO:0010647 56 0.016
negative regulation of defense response GO:0031348 2 0.016
response to hormone GO:0009725 48 0.016
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
anatomical structure homeostasis GO:0060249 36 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
response to abiotic stimulus GO:0009628 122 0.016
Zebrafish
lymphangiogenesis GO:0001946 25 0.016
cell morphogenesis GO:0000902 289 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
hematopoietic stem cell migration GO:0035701 4 0.015
regulation of locomotion GO:0040012 55 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
apoptotic process GO:0006915 116 0.015
defense response to fungus GO:0050832 2 0.015
regulation of metal ion transport GO:0010959 4 0.015
embryonic organ development GO:0048568 381 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
killing of cells of other organism GO:0031640 1 0.015
cell death in response to oxidative stress GO:0036473 2 0.015
response to alkaloid GO:0043279 2 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
head development GO:0060322 303 0.015
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 1 0.015
programmed cell death GO:0012501 119 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of protein transport GO:0051223 3 0.014
immune effector process GO:0002252 23 0.014
regulation of blood pressure GO:0008217 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
cell death GO:0008219 121 0.014
regulation of cell death GO:0010941 103 0.014
ph reduction GO:0045851 1 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
cell projection morphogenesis GO:0048858 244 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
organic acid metabolic process GO:0006082 31 0.014
tube morphogenesis GO:0035239 349 0.014
leukocyte chemotaxis GO:0030595 12 0.014
positive regulation of protein polymerization GO:0032273 2 0.013
vasculature development GO:0001944 278 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
positive regulation of cell activation GO:0050867 1 0.013
heterocycle metabolic process GO:0046483 290 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of protein complex assembly GO:0043254 3 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.013
neutrophil chemotaxis GO:0030593 10 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of anatomical structure size GO:0090066 33 0.012
locomotion GO:0040011 313 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
positive regulation of cell killing GO:0031343 2 0.012
defense response GO:0006952 47 0.012
Mouse
chordate embryonic development GO:0043009 271 0.012
organic substance biosynthetic process GO:1901576 289 0.012
establishment of rna localization GO:0051236 3 0.012
cell motility GO:0048870 244 0.012
single organism transport GO:0044765 206 0.012
regulation of developmental process GO:0050793 247 0.012
nuclear import GO:0051170 3 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
smooth muscle contraction GO:0006939 2 0.012
biosynthetic process GO:0009058 294 0.012
cell chemotaxis GO:0060326 17 0.012
leukocyte homeostasis GO:0001776 2 0.011
regulation of cell communication GO:0010646 232 0.011
ameboidal type cell migration GO:0001667 143 0.011
organic substance catabolic process GO:1901575 28 0.011
Human Mouse
positive regulation of immune effector process GO:0002699 3 0.011
cell killing GO:0001906 2 0.011
proteolysis GO:0006508 38 0.011
Human Mouse
regulation of biological quality GO:0065008 263 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
rna transport GO:0050658 2 0.011
activation of immune response GO:0002253 9 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
amyloid precursor protein metabolic process GO:0042982 1 0.011
cytoskeleton organization GO:0007010 96 0.011
gene expression GO:0010467 252 0.011
regulation of proteolysis GO:0030162 24 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
response to amino acid GO:0043200 2 0.011
striated muscle tissue development GO:0014706 110 0.011
transcription dna templated GO:0006351 181 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of cellular component movement GO:0051270 55 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
phosphorus metabolic process GO:0006793 109 0.011
neural nucleus development GO:0048857 15 0.011
positive regulation of glial cell differentiation GO:0045687 1 0.011
regulation of response to external stimulus GO:0032101 31 0.011
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
regulation of myotube differentiation GO:0010830 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
cellular component morphogenesis GO:0032989 336 0.010
mechanosensory lateral line system development GO:0048881 49 0.010
central nervous system development GO:0007417 387 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
gtp metabolic process GO:0046039 4 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
single organism nuclear import GO:1902593 3 0.010
single organism membrane fusion GO:0044801 2 0.010
cellular amine metabolic process GO:0044106 2 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
dna methylation or demethylation GO:0044728 8 0.010
oxidation reduction process GO:0055114 41 0.010
regulation of gene expression GO:0010468 265 0.010

ctssb.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.092
disease of metabolism DOID:0014667 0 0.074
inherited metabolic disorder DOID:655 0 0.074
immune system disease DOID:2914 0 0.059
lysosomal storage disease DOID:3211 0 0.049
nervous system disease DOID:863 0 0.013
lipid storage disease DOID:9455 0 0.012