Danio rerio

180 known processes

wnt4a

wingless-type MMTV integration site family, member 4a

(Aliases: zgc:136737,MGC136737,wnt4,wnt-4)

wnt4a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 1.000
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 1.000
Zebrafish
hepatic duct development GO:0061011 2 1.000
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 1.000
Zebrafish
mediolateral intercalation GO:0060031 3 0.999
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.999
Zebrafish
spinal cord anterior posterior patterning GO:0021512 1 0.999
Zebrafish
anterior head development GO:0097065 2 0.996
Zebrafish
thrombocyte differentiation GO:0002574 4 0.993
Zebrafish
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.993
Zebrafish
optic placode formation involved in camera type eye formation GO:0046619 3 0.993
Zebrafish
unidimensional cell growth GO:0009826 5 0.993
Zebrafish
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.989
Zebrafish
gall bladder development GO:0061010 1 0.987
Zebrafish
hepatocyte proliferation GO:0072574 2 0.983
Zebrafish
mesodermal cell migration GO:0008078 12 0.979
Zebrafish
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.977
Zebrafish
negative regulation of mitosis GO:0045839 3 0.977
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.976
Zebrafish
optic placode formation GO:0001743 4 0.971
Zebrafish
wnt signaling pathway GO:0016055 80 0.958
Zebrafish Mouse
segmentation GO:0035282 97 0.954
Zebrafish
generation of neurons GO:0048699 385 0.940
dorsal convergence GO:0060030 14 0.936
Zebrafish
somite development GO:0061053 96 0.928
Zebrafish
regulation of anterior head development GO:2000742 2 0.927
Zebrafish
cell part morphogenesis GO:0032990 246 0.925
negative regulation of nuclear division GO:0051784 3 0.912
Zebrafish
brain development GO:0007420 293 0.902
somitogenesis GO:0001756 87 0.891
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.886
Zebrafish Mouse
liver morphogenesis GO:0072576 8 0.878
Zebrafish
otic placode formation GO:0043049 23 0.870
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.861
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.859
ectoderm development GO:0007398 9 0.855
Zebrafish
tube morphogenesis GO:0035239 349 0.851
habenula development GO:0021986 9 0.847
digestive tract morphogenesis GO:0048546 231 0.832
hindbrain development GO:0030902 91 0.822
Zebrafish
regulation of axon guidance GO:1902667 8 0.815
camera type eye development GO:0043010 222 0.814
Zebrafish
neuromast development GO:0048884 46 0.814
Zebrafish
central nervous system development GO:0007417 387 0.814
establishment of spindle localization GO:0051293 12 0.809
Zebrafish
establishment of mitotic spindle localization GO:0040001 12 0.809
Zebrafish
cell projection organization GO:0030030 284 0.803
lateral line development GO:0048882 66 0.802
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.797
Zebrafish
regulation of embryonic development GO:0045995 47 0.793
cell motility GO:0048870 244 0.792
neuron differentiation GO:0030182 353 0.789
neural plate pattern specification GO:0060896 12 0.787
Zebrafish
pancreas development GO:0031016 84 0.786
Zebrafish
establishment of spindle orientation GO:0051294 10 0.782
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.771
head development GO:0060322 303 0.769
microtubule based process GO:0007017 60 0.760
Zebrafish
release of sequestered calcium ion into cytosol GO:0051209 3 0.759
Zebrafish
embryonic pectoral fin morphogenesis GO:0035118 24 0.758
Zebrafish
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.756
Zebrafish
negative regulation of sequestering of calcium ion GO:0051283 4 0.756
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.747
regulation of canonical wnt signaling pathway GO:0060828 34 0.737
Zebrafish
otic vesicle morphogenesis GO:0071600 34 0.737
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.729
Zebrafish Mouse
sensory organ development GO:0007423 393 0.721
Zebrafish
canonical wnt signaling pathway GO:0060070 48 0.721
Zebrafish Mouse
dorsal ventral axis specification GO:0009950 14 0.717
Zebrafish
regionalization GO:0003002 274 0.714
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.711
Zebrafish Mouse
cellular component morphogenesis GO:0032989 336 0.707
cell migration involved in gastrulation GO:0042074 79 0.705
diencephalon development GO:0021536 58 0.701
mesodermal cell fate commitment GO:0001710 14 0.699
Zebrafish
cell migration GO:0016477 237 0.696
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.695
non canonical wnt signaling pathway GO:0035567 13 0.688
Zebrafish Mouse
otic vesicle formation GO:0030916 27 0.681
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.677
Zebrafish
modification dependent protein catabolic process GO:0019941 3 0.676
thalamus development GO:0021794 6 0.675
Zebrafish
embryonic neurocranium morphogenesis GO:0048702 15 0.673
Zebrafish
transcription dna templated GO:0006351 181 0.672
axis specification GO:0009798 43 0.663
Zebrafish
embryonic heart tube development GO:0035050 133 0.658
Zebrafish
eye development GO:0001654 277 0.651
Zebrafish
hindbrain morphogenesis GO:0021575 22 0.650
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.648
single organism cellular localization GO:1902580 46 0.640
Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.635
regulation of sequestering of calcium ion GO:0051282 4 0.632
Zebrafish
single organismal cell cell adhesion GO:0016337 29 0.620
Zebrafish Mouse
neural plate regionalization GO:0060897 10 0.620
Zebrafish
neural tube development GO:0021915 62 0.618
Zebrafish
negative regulation of cellular process GO:0048523 283 0.602
Zebrafish Mouse
appendage morphogenesis GO:0035107 56 0.600
Zebrafish
cell cell signaling involved in cell fate commitment GO:0045168 12 0.599
Zebrafish Mouse
central nervous system neuron differentiation GO:0021953 74 0.597
Zebrafish
ear development GO:0043583 127 0.595
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.590
eye morphogenesis GO:0048592 144 0.587
Zebrafish
branching morphogenesis of an epithelial tube GO:0048754 15 0.581
Mouse
determination of bilateral symmetry GO:0009855 204 0.576
Zebrafish
establishment of mitotic spindle orientation GO:0000132 10 0.571
Zebrafish
gastrulation with mouth forming second GO:0001702 44 0.571
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.570
regulation of cell fate commitment GO:0010453 22 0.568
Zebrafish
ameboidal type cell migration GO:0001667 143 0.566
single organism organelle organization GO:1902589 199 0.552
Zebrafish Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.547
Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.545
epithalamus development GO:0021538 10 0.539
negative regulation of wnt signaling pathway GO:0030178 30 0.537
Zebrafish
liver development GO:0001889 96 0.536
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.533
Zebrafish
cellular protein modification process GO:0006464 100 0.533
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.532
embryonic cranial skeleton morphogenesis GO:0048701 90 0.527
Zebrafish
neural plate development GO:0001840 10 0.526
Zebrafish
positive regulation of cellular process GO:0048522 201 0.520
neuron projection development GO:0031175 180 0.518
neural plate morphogenesis GO:0001839 7 0.517
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.515
cell morphogenesis GO:0000902 289 0.514
negative regulation of signaling GO:0023057 96 0.507
Zebrafish Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.506
aromatic compound biosynthetic process GO:0019438 217 0.505
spindle localization GO:0051653 12 0.502
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.499
neural plate anterior posterior regionalization GO:0021999 8 0.497
Zebrafish
modification dependent macromolecule catabolic process GO:0043632 3 0.489
regulation of axon extension involved in axon guidance GO:0048841 6 0.489
determination of heart left right asymmetry GO:0061371 117 0.488
Zebrafish
axonogenesis GO:0007409 152 0.488
blood vessel development GO:0001568 246 0.485
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 30 0.484
Zebrafish Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.481
death GO:0016265 121 0.481
Mouse
regulation of axonogenesis GO:0050770 32 0.480
chemotaxis GO:0006935 104 0.480
organelle fission GO:0048285 23 0.477
Zebrafish Mouse
lateral line system development GO:0048925 76 0.477
Zebrafish
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.471
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.469
regulation of nervous system development GO:0051960 90 0.467
digestive tract development GO:0048565 265 0.464
immune system development GO:0002520 191 0.460
Zebrafish Mouse
organelle localization GO:0051640 49 0.460
Zebrafish
fourth ventricle development GO:0021592 8 0.460
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.456
Mouse
chordate embryonic development GO:0043009 271 0.452
Zebrafish
cell death GO:0008219 121 0.452
Mouse
organelle organization GO:0006996 227 0.451
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.449
wound healing GO:0042060 90 0.448
negative regulation of cell division GO:0051782 4 0.447
Zebrafish
convergent extension GO:0060026 118 0.447
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.440
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.440
metencephalon development GO:0022037 27 0.440
Zebrafish
ventricular system development GO:0021591 12 0.439
Zebrafish
forebrain regionalization GO:0021871 4 0.438
regulation of wnt signaling pathway GO:0030111 53 0.437
Zebrafish
cell projection morphogenesis GO:0048858 244 0.428
positive regulation of cell communication GO:0010647 56 0.423
Zebrafish
cellular protein catabolic process GO:0044257 4 0.416
stem cell proliferation GO:0072089 4 0.413
cell growth GO:0016049 57 0.408
establishment of localization GO:0051234 244 0.407
Zebrafish Mouse
ectodermal placode development GO:0071696 37 0.404
Zebrafish
endocrine pancreas development GO:0031018 27 0.404
Zebrafish
larval development GO:0002164 2 0.400
regulation of multicellular organismal development GO:2000026 223 0.398
establishment of organelle localization GO:0051656 45 0.397
Zebrafish
protein metabolic process GO:0019538 183 0.394
Zebrafish
pectoral fin development GO:0033339 50 0.390
Zebrafish
swim bladder development GO:0048794 19 0.389
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.388
regulation of chemotaxis GO:0050920 18 0.387
regulation of macromolecule metabolic process GO:0060255 317 0.382
regulation of cell differentiation GO:0045595 142 0.379
regulation of cell division GO:0051302 12 0.377
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.375
Mouse
taxis GO:0042330 109 0.372
phosphorylation GO:0016310 69 0.372
Zebrafish
axon development GO:0061564 166 0.371
cell cycle GO:0007049 93 0.370
Zebrafish Mouse
cell fate specification GO:0001708 68 0.369
mesoderm formation GO:0001707 43 0.363
Zebrafish
signal transduction GO:0007165 455 0.359
Zebrafish Mouse
negative regulation of cell fate commitment GO:0010454 13 0.359
Zebrafish
kupffer s vesicle development GO:0070121 50 0.359
Zebrafish
negative regulation of cell communication GO:0010648 96 0.354
Zebrafish Mouse
regulation of cell cycle GO:0051726 52 0.352
Zebrafish Mouse
epithelium regeneration GO:1990399 14 0.349
digestive system development GO:0055123 289 0.348
positive regulation of cellular biosynthetic process GO:0031328 68 0.348
otolith development GO:0048840 32 0.347
Zebrafish
single organism cell adhesion GO:0098602 29 0.345
Zebrafish Mouse
neuron development GO:0048666 262 0.345
mitotic cell cycle process GO:1903047 48 0.344
Zebrafish
regulation of neurogenesis GO:0050767 87 0.344
locomotion GO:0040011 313 0.343
common bile duct development GO:0061009 13 0.341
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.334
negative regulation of biological process GO:0048519 304 0.331
Zebrafish Mouse
negative regulation of developmental process GO:0051093 65 0.328
Zebrafish Mouse
fin regeneration GO:0031101 51 0.327
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.327
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.326
Zebrafish
negative regulation of axon guidance GO:1902668 1 0.324
regulation of cell communication GO:0010646 232 0.322
Zebrafish Mouse
regulation of cardiac muscle tissue development GO:0055024 1 0.317
mesodermal cell differentiation GO:0048333 21 0.316
Zebrafish
regulation of localization GO:0032879 104 0.316
gland development GO:0048732 143 0.315
Zebrafish Mouse
negative regulation of cell cycle process GO:0010948 9 0.310
Zebrafish
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.309
localization of cell GO:0051674 244 0.308
cell cycle process GO:0022402 53 0.304
Zebrafish Mouse
neural tube patterning GO:0021532 33 0.304
Zebrafish
regulation of neuron projection development GO:0010975 40 0.304
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.301
establishment or maintenance of cell polarity GO:0007163 29 0.300
Zebrafish
embryonic epithelial tube formation GO:0001838 17 0.299
Mouse
cardiac cell fate commitment GO:0060911 1 0.298
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.297
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.296
Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.295
negative regulation of organelle organization GO:0010639 4 0.295
Zebrafish
heart morphogenesis GO:0003007 156 0.294
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.293
Zebrafish
retina development in camera type eye GO:0060041 146 0.286
developmental growth GO:0048589 166 0.286
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.285
Zebrafish
sensory epithelium regeneration GO:0070654 14 0.280
spinal cord patterning GO:0021511 6 0.278
Zebrafish
forebrain anterior posterior pattern specification GO:0021797 3 0.278
embryonic camera type eye formation GO:0060900 10 0.278
Zebrafish
negative regulation of cell differentiation GO:0045596 46 0.277
Zebrafish Mouse
midbrain hindbrain boundary development GO:0030917 23 0.276
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.275
Zebrafish
regulation of signaling GO:0023051 235 0.273
Zebrafish Mouse
notochord development GO:0030903 54 0.273
Zebrafish
cell fate commitment involved in pattern specification GO:0060581 6 0.272
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.270
mitotic cell cycle GO:0000278 64 0.267
Zebrafish
tissue regeneration GO:0042246 74 0.267
cell fate commitment GO:0045165 99 0.263
Zebrafish Mouse
positive regulation of cytokine production GO:0001819 2 0.263
regulation of cell proliferation GO:0042127 37 0.262
regulation of programmed cell death GO:0043067 101 0.262
Mouse
calcium ion homeostasis GO:0055074 19 0.261
Zebrafish
nephron tubule morphogenesis GO:0072078 1 0.258
Mouse
apoptotic process GO:0006915 116 0.257
Mouse
ectodermal placode formation GO:0060788 26 0.255
Zebrafish
mesoderm development GO:0007498 88 0.252
Zebrafish
embryonic pattern specification GO:0009880 44 0.249
Zebrafish
regulation of cell death GO:0010941 103 0.246
Mouse
positive regulation of signaling GO:0023056 56 0.246
Zebrafish
appendage development GO:0048736 80 0.245
Zebrafish
heterocycle metabolic process GO:0046483 290 0.245
regulation of locomotion GO:0040012 55 0.243
positive regulation of muscle organ development GO:0048636 1 0.240
determination of left right symmetry GO:0007368 179 0.238
Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.238
Zebrafish
nephron morphogenesis GO:0072028 2 0.238
Mouse
meiotic nuclear division GO:0007126 4 0.237
Mouse
ion transport GO:0006811 114 0.235
Zebrafish
regulation of endocytosis GO:0030100 7 0.230
Zebrafish
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.230
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 5 0.229
Zebrafish
response to stress GO:0006950 263 0.228
positive regulation of multicellular organismal process GO:0051240 52 0.226
Mouse
cell division GO:0051301 20 0.226
Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.223
Zebrafish
biological adhesion GO:0022610 40 0.222
Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 68 0.221
single organism transport GO:0044765 206 0.221
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.220
formation of primary germ layer GO:0001704 62 0.218
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.217
epithelial tube morphogenesis GO:0060562 148 0.217
Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.214
cellular response to growth factor stimulus GO:0071363 39 0.213
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.211
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.211
regulation of cellular metabolic process GO:0031323 320 0.210
positive regulation of striated muscle tissue development GO:0045844 1 0.208
gene expression GO:0010467 252 0.208
gastrulation GO:0007369 208 0.206
negative regulation of cell cycle GO:0045786 14 0.206
Zebrafish
calcium ion transport into cytosol GO:0060402 3 0.205
Zebrafish
divalent inorganic cation homeostasis GO:0072507 22 0.199
Zebrafish
amine metabolic process GO:0009308 2 0.197
developmental induction GO:0031128 10 0.196
Zebrafish Mouse
maintenance of location GO:0051235 4 0.194
Zebrafish
macromolecule localization GO:0033036 54 0.192
Zebrafish Mouse
endoderm development GO:0007492 49 0.191
Zebrafish
otic vesicle development GO:0071599 42 0.190
Zebrafish
mitotic nuclear division GO:0007067 18 0.189
Zebrafish
gland morphogenesis GO:0022612 13 0.188
Zebrafish Mouse
positive regulation of muscle tissue development GO:1901863 1 0.187
transport GO:0006810 220 0.187
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.186
regulation of signal transduction GO:0009966 225 0.185
Zebrafish Mouse
forebrain neuron differentiation GO:0021879 14 0.183
Zebrafish
regulation of cell cycle process GO:0010564 20 0.180
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.178
epithelial tube formation GO:0072175 19 0.178
Mouse
neuron projection guidance GO:0097485 86 0.178
embryonic heart tube morphogenesis GO:0003143 108 0.177
Zebrafish
central nervous system segmentation GO:0035283 6 0.177
Zebrafish
positive regulation of embryonic development GO:0040019 3 0.176
cellular response to endogenous stimulus GO:0071495 68 0.176
Zebrafish Mouse
chemical homeostasis GO:0048878 49 0.176
Zebrafish
cell adhesion GO:0007155 40 0.175
Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 157 0.172
Zebrafish Mouse
lipid storage GO:0019915 1 0.171
regulation of mesodermal cell fate specification GO:0042661 9 0.171
forebrain development GO:0030900 96 0.171
sequestering of metal ion GO:0051238 3 0.171
Zebrafish
regulation of gene expression GO:0010468 265 0.171
regulation of rna biosynthetic process GO:2001141 213 0.170
axon extension GO:0048675 45 0.168
regulation of establishment of protein localization GO:0070201 4 0.168
heart looping GO:0001947 94 0.168
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.168
Zebrafish
heart field specification GO:0003128 1 0.167
regulation of intracellular protein transport GO:0033157 3 0.166
response to external stimulus GO:0009605 264 0.165
spemann organizer formation GO:0060061 10 0.165
Zebrafish
regulation of phosphorylation GO:0042325 26 0.164
Zebrafish
macromolecule modification GO:0043412 111 0.163
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.163
cellular nitrogen compound biosynthetic process GO:0044271 218 0.158
cellular response to organic substance GO:0071310 105 0.158
Zebrafish Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.157
Zebrafish Mouse
primary neural tube formation GO:0014020 1 0.157
regulation of jun kinase activity GO:0043506 3 0.155
regulation of cell migration GO:0030334 40 0.155
Mouse
sequestering of calcium ion GO:0051208 3 0.153
Zebrafish
behavior GO:0007610 74 0.152
regulation of protein import into nucleus GO:0042306 2 0.151
aging GO:0007568 2 0.151
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.150
Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.150
Mouse
regulation of biological quality GO:0065008 263 0.149
pectoral fin morphogenesis GO:0035138 29 0.148
Zebrafish
regulation of response to stimulus GO:0048583 269 0.147
establishment of cell polarity GO:0030010 18 0.147
Zebrafish
ear morphogenesis GO:0042471 64 0.144
Zebrafish
regulation of response to external stimulus GO:0032101 31 0.143
regulation of non canonical wnt signaling pathway GO:2000050 7 0.143
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.142
Mouse
positive regulation of jnk cascade GO:0046330 3 0.141
angiogenesis GO:0001525 158 0.139
Zebrafish
regulation of axon extension GO:0030516 24 0.139
regulation of behavior GO:0050795 24 0.137
negative regulation of response to stimulus GO:0048585 104 0.137
Zebrafish Mouse
endocrine system development GO:0035270 65 0.137
Zebrafish Mouse
response to organic substance GO:0010033 153 0.136
Zebrafish Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.136
regulation of cellular component organization GO:0051128 86 0.136
regeneration GO:0031099 91 0.135
pharyngeal system development GO:0060037 18 0.135
Zebrafish
cerebellum development GO:0021549 17 0.133
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.132
positive regulation of epithelial cell differentiation GO:0030858 2 0.130
positive regulation of macromolecule metabolic process GO:0010604 93 0.128
microtubule cytoskeleton organization GO:0000226 33 0.128
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.127
Zebrafish Mouse
specification of organ identity GO:0010092 2 0.126
tube closure GO:0060606 1 0.126
myeloid cell differentiation GO:0030099 86 0.125
Zebrafish
patterning of blood vessels GO:0001569 15 0.124
negative regulation of stem cell differentiation GO:2000737 2 0.124
programmed cell death GO:0012501 119 0.124
Mouse
spinal cord development GO:0021510 46 0.122
Zebrafish
positive regulation of biological process GO:0048518 253 0.122
brain segmentation GO:0035284 6 0.121
Zebrafish
hepaticobiliary system development GO:0061008 98 0.121
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.120
regulation of cellular response to growth factor stimulus GO:0090287 35 0.119
Zebrafish Mouse
determination of dorsal identity GO:0048263 13 0.119
Zebrafish
fin morphogenesis GO:0033334 53 0.118
Zebrafish
negative regulation of cellular component organization GO:0051129 16 0.116
Zebrafish
single organism intracellular transport GO:1902582 25 0.116
Zebrafish
hemopoiesis GO:0030097 183 0.116
Zebrafish Mouse
establishment of protein localization to organelle GO:0072594 4 0.114
negative regulation of multicellular organismal process GO:0051241 69 0.113
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.113
Zebrafish
axon guidance GO:0007411 86 0.112
segment polarity determination GO:0007367 1 0.112
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.110
cellular macromolecule biosynthetic process GO:0034645 224 0.109
organic cyclic compound metabolic process GO:1901360 301 0.108
regulation of protein catabolic process GO:0042176 1 0.107
regulation of cellular component movement GO:0051270 55 0.106
biosynthetic process GO:0009058 294 0.105
protein import into nucleus GO:0006606 3 0.104
regulation of organ morphogenesis GO:2000027 35 0.104
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.104
lamellipodium assembly GO:0030032 1 0.103
regulation of gastrulation GO:0010470 24 0.102
protein targeting to nucleus GO:0044744 3 0.102
regulation of cellular protein catabolic process GO:1903362 1 0.101
endocytosis GO:0006897 16 0.100
Zebrafish
positive regulation of wnt signaling pathway GO:0030177 13 0.100
Zebrafish
post anal tail morphogenesis GO:0036342 19 0.100
Zebrafish
positive regulation of cell cycle GO:0045787 3 0.100
Mouse
sensory system development GO:0048880 76 0.100
Zebrafish
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.100
regulation of stem cell proliferation GO:0072091 2 0.098
positive regulation of muscle cell differentiation GO:0051149 1 0.098
cellular amine metabolic process GO:0044106 2 0.098
regulation of cellular amino acid metabolic process GO:0006521 0 0.098
metal ion transport GO:0030001 58 0.098
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.098
Zebrafish Mouse
regulation of epithelial to mesenchymal transition GO:0010717 3 0.097
rostrocaudal neural tube patterning GO:0021903 29 0.096
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.094
positive regulation of cell differentiation GO:0045597 30 0.094
single organism localization GO:1902578 225 0.093
Zebrafish Mouse
cellular component movement GO:0006928 335 0.093
protein phosphorylation GO:0006468 47 0.093
Zebrafish
fin development GO:0033333 77 0.092
Zebrafish
regulation of meiotic cell cycle GO:0051445 1 0.091
Mouse
organ formation GO:0048645 17 0.091
single organism nuclear import GO:1902593 3 0.090
protein localization GO:0008104 40 0.090
Zebrafish Mouse
regulation of mitosis GO:0007088 9 0.090
Zebrafish
smoothened signaling pathway GO:0007224 30 0.089
kidney development GO:0001822 92 0.088
Mouse
positive regulation of nervous system development GO:0051962 25 0.088
rhombomere development GO:0021546 19 0.088
cell proliferation in forebrain GO:0021846 3 0.086
positive regulation of transport GO:0051050 2 0.086
developmental cell growth GO:0048588 52 0.085
embryonic skeletal system development GO:0048706 97 0.084
Zebrafish
axis elongation GO:0003401 31 0.083
Zebrafish
forebrain generation of neurons GO:0021872 14 0.083
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.083
synaptic target recognition GO:0008039 1 0.083
positive regulation of response to external stimulus GO:0032103 9 0.082
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.082
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.082
vasculature development GO:0001944 278 0.081
Zebrafish
protein localization to nucleus GO:0034504 3 0.080
positive regulation of cellular metabolic process GO:0031325 94 0.080
negative regulation of macromolecule metabolic process GO:0010605 76 0.079
Mouse
response to chemical GO:0042221 320 0.077
development of primary female sexual characteristics GO:0046545 4 0.076
Mouse
chromosome organization GO:0051276 31 0.076
mesenchymal cell proliferation GO:0010463 1 0.076
regulation of mitotic cell cycle GO:0007346 25 0.075
Zebrafish
metal ion homeostasis GO:0055065 26 0.075
Zebrafish
embryonic hemopoiesis GO:0035162 53 0.074
regulation of organ growth GO:0046620 3 0.074
response to wounding GO:0009611 116 0.074
morphogenesis of a branching epithelium GO:0061138 16 0.073
Mouse
sensory organ morphogenesis GO:0090596 200 0.072
Zebrafish
anterior posterior axon guidance GO:0033564 5 0.071
proteasomal protein catabolic process GO:0010498 2 0.071
regulation of cell adhesion GO:0030155 15 0.071
Mouse
regulation of protein metabolic process GO:0051246 56 0.071
Zebrafish
positive regulation of developmental process GO:0051094 50 0.071
Mouse
neuroblast proliferation GO:0007405 2 0.071
embryonic eye morphogenesis GO:0048048 30 0.070
Zebrafish
heart formation GO:0060914 13 0.070
striated muscle tissue development GO:0014706 110 0.069
protein import GO:0017038 3 0.069
nucleobase containing compound metabolic process GO:0006139 274 0.069
regulation of protein transport GO:0051223 3 0.068
cellular ketone metabolic process GO:0042180 11 0.068
Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.067
rna metabolic process GO:0016070 219 0.067
cell projection assembly GO:0030031 64 0.066
protein modification process GO:0036211 100 0.066
Zebrafish
growth GO:0040007 174 0.065
forebrain morphogenesis GO:0048853 6 0.064
regulation of transport GO:0051049 45 0.064
Zebrafish
regulation of nuclear division GO:0051783 9 0.064
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.064
cellular amino acid metabolic process GO:0006520 7 0.063
primitive hemopoiesis GO:0060215 27 0.062
hypothalamus development GO:0021854 14 0.062
Zebrafish
cartilage development GO:0051216 96 0.061
Zebrafish
negative regulation of cell fate specification GO:0009996 11 0.061
embryonic organ morphogenesis GO:0048562 274 0.060
Zebrafish
periodic partitioning GO:0007365 1 0.059
regulation of cellular biosynthetic process GO:0031326 245 0.059
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.059

wnt4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.338
bone disease DOID:0080001 0 0.338
disease of anatomical entity DOID:7 0 0.338
musculoskeletal system disease DOID:17 0 0.338
connective tissue disease DOID:65 0 0.338