Danio rerio

0 known processes

stat5.2

signal transducer and activator of transcription 5.2

(Aliases: MGC113865)

stat5.2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.208
Zebrafish Mouse Rat Fly
negative regulation of biological process GO:0048519 304 0.159
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.141
Zebrafish Mouse Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.141
Zebrafish Mouse Rat Fly
gene expression GO:0010467 252 0.119
Zebrafish Mouse Rat Fly
signal transduction GO:0007165 455 0.116
Human Zebrafish Mouse Rat Fly
rna metabolic process GO:0016070 219 0.113
Zebrafish Mouse Rat Fly
aging GO:0007568 2 0.112
regulation of signal transduction GO:0009966 225 0.100
Fly
negative regulation of cellular process GO:0048523 283 0.099
Mouse Fly
locomotion GO:0040011 313 0.099
Fly
larval development GO:0002164 2 0.087
Worm Fly
heterocycle metabolic process GO:0046483 290 0.082
Zebrafish Mouse Rat Fly
regulation of signaling GO:0023051 235 0.078
Fly
multicellular organism growth GO:0035264 4 0.078
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.077
Human Mouse Fly
protein localization to nucleus GO:0034504 3 0.076
nitrogen compound metabolic process GO:0006807 319 0.071
Zebrafish Mouse Rat Fly
cellular amine metabolic process GO:0044106 2 0.069
cellular nitrogen compound biosynthetic process GO:0044271 218 0.068
Zebrafish Mouse Rat Fly
regulation of multicellular organism growth GO:0040014 4 0.067
Mouse
eye development GO:0001654 277 0.065
response to external stimulus GO:0009605 264 0.065
Mouse Rat Fly
maintenance of location GO:0051235 4 0.065
Mouse
single organism localization GO:1902578 225 0.063
Mouse Rat
ameboidal type cell migration GO:0001667 143 0.063
Fly
aromatic compound biosynthetic process GO:0019438 217 0.063
Zebrafish Mouse Rat Fly
establishment of localization GO:0051234 244 0.060
Mouse Rat
establishment of protein localization to organelle GO:0072594 4 0.060
positive regulation of biological process GO:0048518 253 0.060
Zebrafish Mouse Rat Fly
organic substance biosynthetic process GO:1901576 289 0.060
Zebrafish Mouse Rat Fly
phagocytosis GO:0006909 3 0.060
regulation of cellular metabolic process GO:0031323 320 0.060
Zebrafish Mouse Rat Fly
positive regulation of map kinase activity GO:0043406 3 0.059
stem cell maintenance GO:0019827 4 0.059
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.058
Zebrafish Mouse Rat Fly
regulation of primary metabolic process GO:0080090 311 0.058
Zebrafish Mouse Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.058
Zebrafish Mouse Rat Fly
cellular component morphogenesis GO:0032989 336 0.057
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.057
cellular macromolecule metabolic process GO:0044260 391 0.057
Zebrafish Mouse Rat Fly
cytokinesis GO:0000910 3 0.055
nucleobase containing compound biosynthetic process GO:0034654 205 0.055
Zebrafish Mouse Rat Fly
amine metabolic process GO:0009308 2 0.054
small molecule metabolic process GO:0044281 77 0.053
Mouse
regulation of biological quality GO:0065008 263 0.053
Zebrafish Mouse Rat
sensory organ development GO:0007423 393 0.052
extrinsic apoptotic signaling pathway GO:0097191 3 0.052
regulation of cell shape GO:0008360 1 0.052
growth GO:0040007 174 0.051
Mouse
central nervous system development GO:0007417 387 0.051
digestive system development GO:0055123 289 0.051
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.051
regulation of gene expression GO:0010468 265 0.051
Zebrafish Mouse Rat Fly
regionalization GO:0003002 274 0.050
Fly
tube morphogenesis GO:0035239 349 0.050
Fly
regulation of cell communication GO:0010646 232 0.050
Fly
regulation of developmental process GO:0050793 247 0.050
Zebrafish Mouse Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.048
Zebrafish Mouse Rat Fly
immune system development GO:0002520 191 0.047
Zebrafish Mouse Fly
developmental growth GO:0048589 166 0.047
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.047
macromolecule biosynthetic process GO:0009059 227 0.047
Zebrafish Mouse Rat Fly
positive regulation of transport GO:0051050 2 0.047
positive regulation of jnk cascade GO:0046330 3 0.046
double strand break repair GO:0006302 3 0.046
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.046
positive regulation of cellular process GO:0048522 201 0.046
Zebrafish Mouse Rat Fly
immune system process GO:0002376 241 0.045
Zebrafish Mouse Fly
localization of cell GO:0051674 244 0.045
Fly
spermatid development GO:0007286 2 0.044
regulation of macromolecule metabolic process GO:0060255 317 0.044
Zebrafish Mouse Rat Fly
generation of neurons GO:0048699 385 0.044
regulation of cellular amine metabolic process GO:0033238 0 0.044
digestive tract morphogenesis GO:0048546 231 0.043
Fly
response to chemical GO:0042221 320 0.043
Human Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
Zebrafish Mouse Rat Fly
nuclear import GO:0051170 3 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
Zebrafish Mouse Rat Fly
cell projection morphogenesis GO:0048858 244 0.043
cognition GO:0050890 1 0.043
Fly
head development GO:0060322 303 0.042
cell migration GO:0016477 237 0.042
Fly
modification dependent protein catabolic process GO:0019941 3 0.042
nucleic acid metabolic process GO:0090304 244 0.042
Zebrafish Mouse Rat Fly
positive regulation of catabolic process GO:0009896 4 0.041
regulation of cytokine production GO:0001817 3 0.041
Mouse
cell part morphogenesis GO:0032990 246 0.041
peptidyl serine phosphorylation GO:0018105 1 0.041
single organism transport GO:0044765 206 0.041
Mouse Rat
regulation of rna biosynthetic process GO:2001141 213 0.041
Zebrafish Mouse Rat Fly
nuclear transport GO:0051169 4 0.041
gastrulation GO:0007369 208 0.040
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.040
hematopoietic or lymphoid organ development GO:0048534 191 0.040
Zebrafish Mouse Fly
oxoacid metabolic process GO:0043436 31 0.040
Mouse
chemosensory behavior GO:0007635 1 0.040
biosynthetic process GO:0009058 294 0.040
Zebrafish Mouse Rat Fly
pigment granule transport GO:0051904 19 0.040
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.040
negative regulation of protein kinase activity GO:0006469 4 0.040
regulation of establishment of protein localization GO:0070201 4 0.040
rna biosynthetic process GO:0032774 181 0.040
Zebrafish Mouse Rat Fly
regulation of response to nutrient levels GO:0032107 1 0.039
regulation of cellular biosynthetic process GO:0031326 245 0.039
Zebrafish Mouse Rat Fly
protein metabolic process GO:0019538 183 0.039
Mouse
cellular component movement GO:0006928 335 0.039
Rat Fly
positive regulation of cellular catabolic process GO:0031331 3 0.039
cellular biosynthetic process GO:0044249 286 0.039
Zebrafish Mouse Rat Fly
cellular protein catabolic process GO:0044257 4 0.038
specification of symmetry GO:0009799 204 0.038
response to carbohydrate GO:0009743 3 0.038
regulation of apoptotic process GO:0042981 98 0.037
Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.037
cellular protein modification process GO:0006464 100 0.037
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
Zebrafish Mouse Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
regulation of transcription dna templated GO:0006355 213 0.037
Zebrafish Mouse Rat Fly
response to stress GO:0006950 263 0.037
Mouse Rat Fly
peptidyl serine modification GO:0018209 2 0.037
positive regulation of stress activated mapk cascade GO:0032874 3 0.037
guanosine containing compound catabolic process GO:1901069 2 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
Zebrafish Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
brain development GO:0007420 293 0.036
regulation of biosynthetic process GO:0009889 250 0.036
Zebrafish Mouse Rat Fly
organonitrogen compound metabolic process GO:1901564 74 0.035
Mouse
response to drug GO:0042493 3 0.035
cell morphogenesis GO:0000902 289 0.035
Fly
nucleic acid templated transcription GO:0097659 181 0.035
Zebrafish Mouse Rat Fly
epithelial cell differentiation GO:0030855 116 0.035
Mouse Fly
gtp metabolic process GO:0046039 4 0.035
positive regulation of cell communication GO:0010647 56 0.035
regulation of response to stimulus GO:0048583 269 0.035
Mouse Fly
spermatid differentiation GO:0048515 2 0.035
pigmentation GO:0043473 85 0.034
cell projection organization GO:0030030 284 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
regulation of multicellular organismal development GO:2000026 223 0.034
Zebrafish Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.033
positive regulation of exocytosis GO:0045921 1 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
Zebrafish Mouse Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
Zebrafish Mouse Fly
cell motility GO:0048870 244 0.033
Fly
regulation of cell activation GO:0050865 1 0.033
Mouse
nucleocytoplasmic transport GO:0006913 4 0.033
single organism metabolic process GO:0044710 217 0.033
Mouse
cellular ketone metabolic process GO:0042180 11 0.033
Mouse
positive regulation of cell adhesion GO:0045785 1 0.033
enzyme linked receptor protein signaling pathway GO:0007167 106 0.032
Human Mouse
adult behavior GO:0030534 2 0.032
microtubule based process GO:0007017 60 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
transport GO:0006810 220 0.032
Mouse Rat
response to organic substance GO:0010033 153 0.032
Human Mouse Rat Fly
protein secretion GO:0009306 1 0.032
neuroblast proliferation GO:0007405 2 0.032
homeostatic process GO:0042592 142 0.032
Zebrafish Mouse
carboxylic acid metabolic process GO:0019752 22 0.032
Mouse
cellular component assembly GO:0022607 170 0.032
digestive tract development GO:0048565 265 0.031
Fly
cellular component biogenesis GO:0044085 178 0.031
response to biotic stimulus GO:0009607 97 0.031
Rat Fly
exocytosis GO:0006887 1 0.031
transcription dna templated GO:0006351 181 0.031
Zebrafish Mouse Rat Fly
regulation of protein transport GO:0051223 3 0.031
mononuclear cell proliferation GO:0032943 1 0.031
Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.031
cellular amino acid metabolic process GO:0006520 7 0.031
Mouse
intracellular signal transduction GO:0035556 85 0.031
Human Zebrafish Mouse Rat Fly
organic acid metabolic process GO:0006082 31 0.030
Mouse
regulation of response to extracellular stimulus GO:0032104 1 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
Zebrafish Mouse Rat Fly
convergent extension GO:0060026 118 0.030
leukocyte proliferation GO:0070661 1 0.030
Mouse
regulation of synapse organization GO:0050807 3 0.030
cellular protein metabolic process GO:0044267 129 0.030
Mouse
morphogenesis of an epithelium GO:0002009 333 0.030
Mouse
neuron differentiation GO:0030182 353 0.030
single organism nuclear import GO:1902593 3 0.030
protein targeting to nucleus GO:0044744 3 0.030
erk1 and erk2 cascade GO:0070371 4 0.030
convergent extension involved in gastrulation GO:0060027 71 0.030
microtubule organizing center organization GO:0031023 1 0.030
protein import GO:0017038 3 0.030
endosomal transport GO:0016197 2 0.029
camera type eye development GO:0043010 222 0.029
positive regulation of cell cycle GO:0045787 3 0.029
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
Zebrafish Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
Zebrafish Mouse Rat Fly
tissue remodeling GO:0048771 4 0.029
Rat
positive regulation of protein complex assembly GO:0031334 2 0.029
positive regulation of cytokine production GO:0001819 2 0.029
Mouse
locomotor rhythm GO:0045475 3 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
cilium morphogenesis GO:0060271 85 0.028
regulation of reactive oxygen species metabolic process GO:2000377 2 0.028
melanosome transport GO:0032402 19 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
neuron projection development GO:0031175 180 0.028
cilium organization GO:0044782 71 0.028
cytoskeleton dependent cytokinesis GO:0061640 3 0.028
positive regulation of apoptotic signaling pathway GO:2001235 1 0.027
compound eye development GO:0048749 2 0.027
cellular response to lipopolysaccharide GO:0071222 3 0.027
Fly
lymphocyte proliferation GO:0046651 1 0.027
Mouse
response to wounding GO:0009611 116 0.026
Mouse
regulation of binding GO:0051098 3 0.026
single organism organelle organization GO:1902589 199 0.026
macromolecule modification GO:0043412 111 0.026
Mouse
negative regulation of metabolic process GO:0009892 86 0.026
cellular response to organic substance GO:0071310 105 0.026
Human Mouse Rat Fly
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.026
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.026
regulation of protein catabolic process GO:0042176 1 0.026
regulation of cell development GO:0060284 100 0.025
negative regulation of nuclear division GO:0051784 3 0.025
developmental programmed cell death GO:0010623 4 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
positive regulation of gtp catabolic process GO:0033126 1 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
apoptotic process GO:0006915 116 0.025
Mouse
cellular response to chemical stimulus GO:0070887 157 0.025
Human Mouse Rat Fly
system process GO:0003008 185 0.025
Fly
regulation of cell projection assembly GO:0060491 4 0.025
hemopoiesis GO:0030097 183 0.025
Zebrafish Mouse Fly
gland development GO:0048732 143 0.024
Mouse Rat Fly
pigment granule localization GO:0051875 25 0.024
regulation of synapse assembly GO:0051963 3 0.024
gtp catabolic process GO:0006184 2 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
cellular response to hormone stimulus GO:0032870 39 0.024
Human Mouse
organelle organization GO:0006996 227 0.024
positive regulation of cell activation GO:0050867 1 0.024
Mouse
axonogenesis GO:0007409 152 0.024
neuron development GO:0048666 262 0.024
regulation of carbohydrate metabolic process GO:0006109 4 0.024
regulation of programmed cell death GO:0043067 101 0.024
Mouse
microtubule based movement GO:0007018 33 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
Fly
vasculature development GO:0001944 278 0.024
cellular response to external stimulus GO:0071496 2 0.024
stem cell proliferation GO:0072089 4 0.024
embryonic organ morphogenesis GO:0048562 274 0.023
cilium assembly GO:0042384 58 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
segmentation GO:0035282 97 0.023
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
Zebrafish Mouse Rat Fly
angiogenesis GO:0001525 158 0.023
axon development GO:0061564 166 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
positive regulation of secretion GO:0051047 1 0.023
phosphorus metabolic process GO:0006793 109 0.022
Mouse
negative regulation of kinase activity GO:0033673 4 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
Zebrafish Mouse Rat Fly
blood vessel morphogenesis GO:0048514 216 0.022
positive regulation of protein kinase b signaling GO:0051897 1 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
chordate embryonic development GO:0043009 271 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
osteoclast differentiation GO:0030316 1 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
lipid storage GO:0019915 1 0.022
Mouse
signal transduction in absence of ligand GO:0038034 1 0.022
membrane fusion GO:0061025 2 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
regulation of production of molecular mediator of immune response GO:0002700 1 0.022
response to abiotic stimulus GO:0009628 122 0.021
Rat Fly
protein modification process GO:0036211 100 0.021
Mouse
positive regulation of metabolic process GO:0009893 108 0.021
Zebrafish Mouse Fly
muscle structure development GO:0061061 196 0.021
Fly
phosphate containing compound metabolic process GO:0006796 108 0.021
Mouse
eye morphogenesis GO:0048592 144 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
Zebrafish Mouse Fly
regulation of organelle assembly GO:1902115 4 0.021
regulation of jak stat cascade GO:0046425 3 0.021
Fly
germ line stem cell maintenance GO:0030718 2 0.021
Fly
somitogenesis GO:0001756 87 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
response to other organism GO:0051707 97 0.021
Rat Fly
wnt signaling pathway GO:0016055 80 0.021
Fly
negative regulation of developmental process GO:0051093 65 0.021
Mouse Fly
stem cell differentiation GO:0048863 117 0.021
Fly
regulation of gtp catabolic process GO:0033124 2 0.021
b cell activation GO:0042113 2 0.021
Mouse
death GO:0016265 121 0.021
Mouse
positive regulation of signaling GO:0023056 56 0.021
neuron projection morphogenesis GO:0048812 161 0.021
rna localization GO:0006403 4 0.021
regulation of rna metabolic process GO:0051252 224 0.020
Zebrafish Mouse Rat Fly
centrosome organization GO:0051297 1 0.020
regulation of wound healing GO:0061041 2 0.020
activation of mapk activity GO:0000187 3 0.020
regulation of nervous system development GO:0051960 90 0.020
positive regulation of signal transduction GO:0009967 56 0.020
organelle fusion GO:0048284 3 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
Human Mouse Rat
regulation of cell death GO:0010941 103 0.020
Mouse
mitochondrion organization GO:0007005 4 0.020
regulation of calcium ion transport GO:0051924 2 0.020
establishment of melanosome localization GO:0032401 19 0.020
establishment of pigment granule localization GO:0051905 22 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
Fly
response to hexose GO:0009746 3 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
response to hormone GO:0009725 48 0.020
Human Mouse Rat
positive regulation of gene expression GO:0010628 71 0.019
Zebrafish Mouse Fly
regulation of reproductive process GO:2000241 4 0.019
cellular pigmentation GO:0033059 30 0.019
actin filament based movement GO:0030048 1 0.019
cilium movement GO:0003341 26 0.019
hepaticobiliary system development GO:0061008 98 0.019
Rat
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
negative regulation of cytokine production GO:0001818 1 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.019
regulation of glucose import GO:0046324 1 0.018
regulation of molecular function GO:0065009 70 0.018
cytokinetic process GO:0032506 2 0.018
atp catabolic process GO:0006200 4 0.018
cell death GO:0008219 121 0.018
Mouse
embryonic organ development GO:0048568 381 0.018
response to monosaccharide GO:0034284 3 0.018
tyrosine phosphorylation of stat protein GO:0007260 1 0.018
response to glucose GO:0009749 3 0.018
glucose homeostasis GO:0042593 1 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
regulation of wnt signaling pathway GO:0030111 53 0.018
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
Zebrafish Mouse Fly
stem cell division GO:0017145 1 0.018
Fly
autophagy GO:0006914 4 0.018
membrane invagination GO:0010324 1 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
positive regulation of jun kinase activity GO:0043507 2 0.018
regulation of metal ion transport GO:0010959 4 0.018
negative regulation of cell communication GO:0010648 96 0.018
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.018
Fly
phagocytosis engulfment GO:0006911 1 0.018
response to endogenous stimulus GO:0009719 83 0.018
Human Mouse Rat
single organism membrane fusion GO:0044801 2 0.017
cellular response to nutrient levels GO:0031669 2 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
Mouse
positive regulation of neuron apoptotic process GO:0043525 1 0.017
cell projection assembly GO:0030031 64 0.017
regulation of catalytic activity GO:0050790 55 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
regulation of locomotion GO:0040012 55 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
protein phosphorylation GO:0006468 47 0.017
Mouse
protein acetylation GO:0006473 2 0.016
meiotic nuclear division GO:0007126 4 0.016
cellular localization GO:0051641 97 0.016
determination of bilateral symmetry GO:0009855 204 0.016
developmental pigmentation GO:0048066 48 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
regulation of protein binding GO:0043393 3 0.016
regulation of jun kinase activity GO:0043506 3 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
negative regulation of catabolic process GO:0009895 3 0.016
negative regulation of protein transport GO:0051224 3 0.016
heart development GO:0007507 313 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
Zebrafish Mouse Fly
regulation of cell differentiation GO:0045595 142 0.016
Zebrafish Mouse Fly
embryonic heart tube morphogenesis GO:0003143 108 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.015
glial cell migration GO:0008347 3 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of protein metabolic process GO:0051246 56 0.015
Mouse
negative regulation of mapk cascade GO:0043409 4 0.015
positive regulation of leukocyte migration GO:0002687 2 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
Zebrafish Mouse Fly
ion homeostasis GO:0050801 41 0.015
mitotic cell cycle GO:0000278 64 0.015
Mouse
regulation of receptor activity GO:0010469 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
multi organism process GO:0051704 134 0.015
Mouse Rat Fly
negative regulation of apoptotic process GO:0043066 55 0.015
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
heart morphogenesis GO:0003007 156 0.015
regulation of neurogenesis GO:0050767 87 0.015
erythrocyte homeostasis GO:0034101 55 0.015
Zebrafish Mouse
negative regulation of mitosis GO:0045839 3 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
regulation of mrna processing GO:0050684 3 0.015
myotube differentiation GO:0014902 45 0.015
taxis GO:0042330 109 0.015
homeostasis of number of cells GO:0048872 62 0.015
Zebrafish Mouse
cell adhesion mediated by integrin GO:0033627 1 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
startle response GO:0001964 4 0.015
negative regulation of cell death GO:0060548 60 0.015
Mouse
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
regulation of cell motility GO:2000145 46 0.015
response to external biotic stimulus GO:0043207 97 0.015
Rat Fly
regulation of dendrite development GO:0050773 3 0.015
cell migration involved in gastrulation GO:0042074 79 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
Zebrafish Mouse Fly
positive regulation of neuron death GO:1901216 1 0.015
negative regulation of gene expression GO:0010629 65 0.015
positive regulation of translation GO:0045727 1 0.015
cell proliferation GO:0008283 80 0.015
Mouse Rat Fly
regulation of blood pressure GO:0008217 1 0.014
response to bacterium GO:0009617 58 0.014
Rat Fly
regulation of meiotic cell cycle GO:0051445 1 0.014
tube closure GO:0060606 1 0.014
mitotic cytokinesis GO:0000281 3 0.014
stem cell development GO:0048864 82 0.014
Fly
negative regulation of synapse assembly GO:0051964 2 0.014
phosphorylation GO:0016310 69 0.014
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.014
Zebrafish Mouse Fly
neutrophil mediated immunity GO:0002446 1 0.014
ras protein signal transduction GO:0007265 7 0.014
skeletal system development GO:0001501 181 0.014
regulation of cell proliferation GO:0042127 37 0.014
Mouse Rat Fly
skeletal muscle organ development GO:0060538 78 0.014
sensory organ morphogenesis GO:0090596 200 0.014
cellular response to starvation GO:0009267 1 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
Mouse
carbohydrate homeostasis GO:0033500 1 0.014
cellular response to stress GO:0033554 62 0.014
antimicrobial humoral response GO:0019730 2 0.014
Fly
periodic partitioning GO:0007365 1 0.014
organelle localization GO:0051640 49 0.014
defense response GO:0006952 47 0.014
Mouse Rat Fly
regulation of gtpase activity GO:0043087 2 0.014
inner ear development GO:0048839 126 0.014
post embryonic organ development GO:0048569 4 0.013
Fly
blood vessel development GO:0001568 246 0.013
regulation of cellular component organization GO:0051128 86 0.013
regulation of dna replication GO:0006275 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
Zebrafish Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
anatomical structure homeostasis GO:0060249 36 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
fertilization GO:0009566 3 0.013
determination of left right symmetry GO:0007368 179 0.013
cell matrix adhesion GO:0007160 4 0.013
liver development GO:0001889 96 0.013
Rat
positive regulation of cytoskeleton organization GO:0051495 3 0.013
pancreas development GO:0031016 84 0.013
programmed cell death GO:0012501 119 0.013
Mouse
b cell differentiation GO:0030183 1 0.013
Mouse
cellular biogenic amine metabolic process GO:0006576 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
blood circulation GO:0008015 87 0.013
stem cell fate commitment GO:0048865 1 0.013
cellular respiration GO:0045333 3 0.013
anterior posterior pattern specification GO:0009952 152 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
Mouse
muscle cell differentiation GO:0042692 139 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
Mouse
striated muscle cell differentiation GO:0051146 129 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
Zebrafish Mouse Fly
lipid metabolic process GO:0006629 52 0.013
Mouse
bone remodeling GO:0046849 2 0.013
circulatory system process GO:0003013 87 0.013
lamellipodium organization GO:0097581 1 0.013
cell cycle GO:0007049 93 0.013
Mouse
osteoclast development GO:0036035 1 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
Mouse
female sex differentiation GO:0046660 4 0.013
Mouse Rat
internal peptidyl lysine acetylation GO:0018393 2 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
primary neural tube formation GO:0014020 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
wound healing GO:0042060 90 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cell substrate junction assembly GO:0007044 2 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012

stat5.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
disease of cellular proliferation DOID:14566 0 0.030
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.024
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.017
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016