Danio rerio

31 known processes

LOC563363

cholesterol side-chain cleavage enzyme, mitochondrial-like

LOC563363 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 1 0.148
positive regulation of camp biosynthetic process GO:0030819 2 0.106
regulation of sequestering of calcium ion GO:0051282 4 0.098
regulation of synapse assembly GO:0051963 3 0.096
regulation of synapse organization GO:0050807 3 0.081
purine nucleotide biosynthetic process GO:0006164 20 0.079
cytosolic calcium ion transport GO:0060401 3 0.072
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.071
maintenance of location GO:0051235 4 0.069
positive regulation of camp metabolic process GO:0030816 2 0.069
larval development GO:0002164 2 0.065
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.064
sequestering of calcium ion GO:0051208 3 0.063
actin polymerization or depolymerization GO:0008154 2 0.060
negative regulation of synapse assembly GO:0051964 2 0.059
cyclic nucleotide biosynthetic process GO:0009190 18 0.056
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.056
synaptic growth at neuromuscular junction GO:0051124 2 0.055
amine metabolic process GO:0009308 2 0.052
signal transduction GO:0007165 455 0.051
negative regulation of sequestering of calcium ion GO:0051283 4 0.051
carboxylic acid metabolic process GO:0019752 22 0.050
cellular response to external stimulus GO:0071496 2 0.049
chemosensory behavior GO:0007635 1 0.048
sequestering of metal ion GO:0051238 3 0.048
regulation of cellular amine metabolic process GO:0033238 0 0.047
head development GO:0060322 303 0.044
cellular amine metabolic process GO:0044106 2 0.041
tyrosine phosphorylation of stat protein GO:0007260 1 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
digestive tract development GO:0048565 265 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.040
system process GO:0003008 185 0.039
aging GO:0007568 2 0.038
purine ribonucleotide biosynthetic process GO:0009152 20 0.038
cellular ketone metabolic process GO:0042180 11 0.038
regulation of inflammatory response GO:0050727 2 0.036
morphogenesis of an epithelium GO:0002009 333 0.035
cytokinesis GO:0000910 3 0.035
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.035
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.034
release of sequestered calcium ion into cytosol GO:0051209 3 0.034
organonitrogen compound metabolic process GO:1901564 74 0.033
locomotion GO:0040011 313 0.033
nuclear transport GO:0051169 4 0.032
cell surface receptor signaling pathway GO:0007166 325 0.031
phosphorus metabolic process GO:0006793 109 0.031
regulation of jak stat cascade GO:0046425 3 0.030
positive regulation of catabolic process GO:0009896 4 0.030
positive regulation of cell activation GO:0050867 1 0.030
small molecule metabolic process GO:0044281 77 0.030
negative regulation of biological process GO:0048519 304 0.030
guanosine containing compound metabolic process GO:1901068 4 0.030
brain development GO:0007420 293 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
g protein coupled receptor signaling pathway GO:0007186 74 0.028
leukocyte proliferation GO:0070661 1 0.028
gene expression GO:0010467 252 0.028
calcium ion transport into cytosol GO:0060402 3 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
antimicrobial humoral response GO:0019730 2 0.027
response to carbohydrate GO:0009743 3 0.027
adherens junction organization GO:0034332 4 0.027
oxoacid metabolic process GO:0043436 31 0.027
lipid storage GO:0019915 1 0.027
protein localization to nucleus GO:0034504 3 0.027
digestive tract morphogenesis GO:0048546 231 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
regulation of signaling GO:0023051 235 0.026
neuroblast proliferation GO:0007405 2 0.026
cellular component movement GO:0006928 335 0.026
regulation of binding GO:0051098 3 0.025
cell projection morphogenesis GO:0048858 244 0.025
regulation of signal transduction GO:0009966 225 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of reproductive process GO:2000241 4 0.024
regulation of camp biosynthetic process GO:0030817 9 0.024
multicellular organism growth GO:0035264 4 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
ribose phosphate biosynthetic process GO:0046390 20 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
central nervous system development GO:0007417 387 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
phagocytosis GO:0006909 3 0.023
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.023
response to drug GO:0042493 3 0.023
cyclic purine nucleotide metabolic process GO:0052652 18 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
guanosine containing compound catabolic process GO:1901069 2 0.022
zymogen activation GO:0031638 3 0.022
purine containing compound metabolic process GO:0072521 29 0.022
positive regulation of reproductive process GO:2000243 2 0.022
mitochondrion organization GO:0007005 4 0.022
neuron differentiation GO:0030182 353 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
energy reserve metabolic process GO:0006112 2 0.021
regulation of nucleotide biosynthetic process GO:0030808 15 0.021
cell migration GO:0016477 237 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
immune response activating signal transduction GO:0002757 5 0.021
regulation of metal ion transport GO:0010959 4 0.021
regulation of cell communication GO:0010646 232 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
cortical actin cytoskeleton organization GO:0030866 1 0.021
gtp metabolic process GO:0046039 4 0.021
cell part morphogenesis GO:0032990 246 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
melanin metabolic process GO:0006582 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.020
cation transport GO:0006812 81 0.020
single organism membrane fusion GO:0044801 2 0.020
establishment of endothelial barrier GO:0061028 3 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
meiotic cell cycle process GO:1903046 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
spermatid differentiation GO:0048515 2 0.020
positive regulation of transport GO:0051050 2 0.020
cellular component morphogenesis GO:0032989 336 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
establishment of organelle localization GO:0051656 45 0.019
nucleotide biosynthetic process GO:0009165 21 0.019
tube morphogenesis GO:0035239 349 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
ion transport GO:0006811 114 0.019
regionalization GO:0003002 274 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
positive regulation of cell cycle GO:0045787 3 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.018
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
gastrulation GO:0007369 208 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
single organism nuclear import GO:1902593 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of biological quality GO:0065008 263 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
response to monosaccharide GO:0034284 3 0.018
jak stat cascade GO:0007259 5 0.018
nuclear import GO:0051170 3 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
organic substance biosynthetic process GO:1901576 289 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
organic acid metabolic process GO:0006082 31 0.018
heterocycle biosynthetic process GO:0018130 215 0.017
stem cell proliferation GO:0072089 4 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
neurotransmitter transport GO:0006836 2 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
regulation of cell activation GO:0050865 1 0.017
cellular biosynthetic process GO:0044249 286 0.017
regulation of metabolic process GO:0019222 359 0.017
protein targeting to nucleus GO:0044744 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
exocytosis GO:0006887 1 0.017
biosynthetic process GO:0009058 294 0.017
nucleoside phosphate biosynthetic process GO:1901293 21 0.017
cell morphogenesis GO:0000902 289 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
regulation of blood vessel size GO:0050880 2 0.017
organelle fusion GO:0048284 3 0.017
protein localization to cell surface GO:0034394 3 0.017
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
stem cell maintenance GO:0019827 4 0.016
cellular protein catabolic process GO:0044257 4 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
response to other organism GO:0051707 97 0.016
peptide transport GO:0015833 1 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
regulation of protein complex assembly GO:0043254 3 0.016
translational initiation GO:0006413 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
regulation of tube size GO:0035150 2 0.016
membrane fusion GO:0061025 2 0.016
regulation of purine nucleotide metabolic process GO:1900542 17 0.016
striated muscle tissue development GO:0014706 110 0.016
rna localization GO:0006403 4 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
single organism metabolic process GO:0044710 217 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
digestive system development GO:0055123 289 0.016
female gonad development GO:0008585 4 0.015
macromolecule modification GO:0043412 111 0.015
growth GO:0040007 174 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
carbohydrate derivative biosynthetic process GO:1901137 43 0.015
cellular response to starvation GO:0009267 1 0.015
autophagy GO:0006914 4 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
spermatid development GO:0007286 2 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
protein import GO:0017038 3 0.015
neurotransmitter secretion GO:0007269 2 0.015
mononuclear cell proliferation GO:0032943 1 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
interspecies interaction between organisms GO:0044419 4 0.015
regulation of developmental process GO:0050793 247 0.015
gtp catabolic process GO:0006184 2 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
cytoplasm organization GO:0007028 4 0.015
programmed cell death GO:0012501 119 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
secondary metabolic process GO:0019748 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
protein acetylation GO:0006473 2 0.015
response to hexose GO:0009746 3 0.015
neuron development GO:0048666 262 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
calcium ion transport GO:0006816 18 0.014
golgi vesicle transport GO:0048193 3 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
atp catabolic process GO:0006200 4 0.014
xenobiotic metabolic process GO:0006805 4 0.014
camp biosynthetic process GO:0006171 11 0.014
protein import into nucleus GO:0006606 3 0.014
cell projection organization GO:0030030 284 0.014
regulation of response to stimulus GO:0048583 269 0.014
regulation of calcium ion transport GO:0051924 2 0.014
response to uv GO:0009411 3 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
regulation of nucleotide metabolic process GO:0006140 17 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
lipid homeostasis GO:0055088 3 0.014
macroautophagy GO:0016236 1 0.014
regulation of protein targeting GO:1903533 2 0.014
alcohol biosynthetic process GO:0046165 2 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
lymphocyte proliferation GO:0046651 1 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of protein catabolic process GO:0042176 1 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
intracellular signal transduction GO:0035556 85 0.014
regulation of cytokine production GO:0001817 3 0.014
sleep GO:0030431 1 0.014
developmental growth GO:0048589 166 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
cell motility GO:0048870 244 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of camp metabolic process GO:0030814 9 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
macromolecular complex disassembly GO:0032984 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
meiotic nuclear division GO:0007126 4 0.013
axon development GO:0061564 166 0.013
neuron projection morphogenesis GO:0048812 161 0.013
b cell mediated immunity GO:0019724 3 0.013
energy homeostasis GO:0097009 3 0.013
negative regulation of reproductive process GO:2000242 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
metal ion transport GO:0030001 58 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
positive regulation of cell division GO:0051781 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
positive regulation of immune effector process GO:0002699 3 0.012
response to alkaloid GO:0043279 2 0.012
adherens junction maintenance GO:0034334 2 0.012
epidermal cell fate specification GO:0009957 4 0.012
axon guidance GO:0007411 86 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
female sex differentiation GO:0046660 4 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
negative regulation of defense response GO:0031348 2 0.012
activation of immune response GO:0002253 9 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of multi organism process GO:0043902 3 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
negative regulation of cellular process GO:0048523 283 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
apoptotic process involved in development GO:1902742 2 0.012
cell aging GO:0007569 2 0.012
organic acid catabolic process GO:0016054 3 0.012
anterior posterior pattern specification GO:0009952 152 0.012
fertilization GO:0009566 3 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
developmental programmed cell death GO:0010623 4 0.012
organelle localization GO:0051640 49 0.012
regulation of blood pressure GO:0008217 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
purine containing compound biosynthetic process GO:0072522 20 0.011
protein modification process GO:0036211 100 0.011
cellular localization GO:0051641 97 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
response to stress GO:0006950 263 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
wnt signaling pathway GO:0016055 80 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
immune system process GO:0002376 241 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
adult behavior GO:0030534 2 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
heterocycle metabolic process GO:0046483 290 0.011
response to glucose GO:0009749 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
positive regulation of metabolic process GO:0009893 108 0.011
single organism transport GO:0044765 206 0.011
reactive oxygen species metabolic process GO:0072593 6 0.011
axonogenesis GO:0007409 152 0.011
single fertilization GO:0007338 3 0.011
ovulation cycle GO:0042698 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
neuron projection development GO:0031175 180 0.011
muscle structure development GO:0061061 196 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of nervous system development GO:0051960 90 0.011
response to nutrient GO:0007584 3 0.011
regulation of cell shape GO:0008360 1 0.011
cellular component disassembly GO:0022411 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
heart development GO:0007507 313 0.011
small molecule catabolic process GO:0044282 3 0.011
long chain fatty acid transport GO:0015909 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
calcium mediated signaling GO:0019722 2 0.011
specification of symmetry GO:0009799 204 0.011
hormone secretion GO:0046879 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
protein acylation GO:0043543 3 0.011
periodic partitioning GO:0007365 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
gland development GO:0048732 143 0.011
tube closure GO:0060606 1 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
dicarboxylic acid transport GO:0006835 1 0.011
protein complex disassembly GO:0043241 1 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
carboxylic acid catabolic process GO:0046395 3 0.010
synaptic vesicle transport GO:0048489 1 0.010
organophosphate biosynthetic process GO:0090407 23 0.010
organelle organization GO:0006996 227 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
fat soluble vitamin metabolic process GO:0006775 4 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
regulation of biosynthetic process GO:0009889 250 0.010
transport GO:0006810 220 0.010
convergent extension GO:0060026 118 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cellular response to hypoxia GO:0071456 1 0.010
response to wounding GO:0009611 116 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
response to vitamin GO:0033273 3 0.010
positive regulation of neural precursor cell proliferation GO:2000179 1 0.010
b cell activation GO:0042113 2 0.010
apoptotic process involved in morphogenesis GO:0060561 2 0.010
synaptic vesicle localization GO:0097479 1 0.010
nucleotide metabolic process GO:0009117 28 0.010
camera type eye development GO:0043010 222 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
phototransduction GO:0007602 2 0.010
response to external stimulus GO:0009605 264 0.010
response to amine GO:0014075 1 0.010
glucose homeostasis GO:0042593 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
single organism localization GO:1902578 225 0.010

LOC563363 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.061
sensory system disease DOID:0050155 0 0.061
disease of anatomical entity DOID:7 0 0.061
eye and adnexa disease DOID:1492 0 0.061
nervous system disease DOID:863 0 0.061
eye disease DOID:5614 0 0.061
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.013
musculoskeletal system disease DOID:17 0 0.012
retinal degeneration DOID:8466 0 0.011