Danio rerio

28 known processes

scn1ba

sodium channel, voltage-gated, type I, beta a

(Aliases: scn1b,si:ch211-265p12.1)

scn1ba biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 91 0.936
sodium ion transport GO:0006814 24 0.877
cation transport GO:0006812 81 0.832
detection of abiotic stimulus GO:0009582 24 0.764
sodium ion transmembrane transport GO:0035725 21 0.748
ion transport GO:0006811 114 0.736
transmembrane transport GO:0055085 120 0.699
neuron development GO:0048666 262 0.643
Mouse
transmission of nerve impulse GO:0019226 19 0.596
Mouse
generation of neurons GO:0048699 385 0.589
Mouse
astrocyte differentiation GO:0048708 1 0.586
sensory organ development GO:0007423 393 0.495
neuron differentiation GO:0030182 353 0.409
Mouse
inorganic cation transmembrane transport GO:0098662 50 0.385
response to abiotic stimulus GO:0009628 122 0.361
detection of stimulus GO:0051606 29 0.356
heart development GO:0007507 313 0.345
cell projection organization GO:0030030 284 0.336
Mouse
cation transmembrane transport GO:0098655 65 0.323
system process GO:0003008 185 0.316
Mouse
axonogenesis GO:0007409 152 0.302
Mouse
detection of visible light GO:0009584 12 0.296
inorganic ion transmembrane transport GO:0098660 57 0.295
response to external stimulus GO:0009605 264 0.290
Mouse
axon development GO:0061564 166 0.289
Mouse
heart morphogenesis GO:0003007 156 0.277
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.265
detection of external stimulus GO:0009581 24 0.259
swimming behavior GO:0036269 8 0.239
cell projection morphogenesis GO:0048858 244 0.224
Mouse
action potential GO:0001508 19 0.213
Mouse
lateral line system development GO:0048925 76 0.209
negative regulation of response to cytokine stimulus GO:0060761 2 0.203
multicellular organismal signaling GO:0035637 22 0.182
Mouse
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.177
locomotion GO:0040011 313 0.156
Mouse
regulation of ion transport GO:0043269 22 0.154
myofibril assembly GO:0030239 48 0.147
cell surface receptor signaling pathway GO:0007166 325 0.139
photoreceptor cell differentiation GO:0046530 55 0.136
cellular component biogenesis GO:0044085 178 0.134
mechanosensory behavior GO:0007638 2 0.131
cellular component movement GO:0006928 335 0.126
Mouse
neuronal action potential GO:0019228 18 0.118
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.117
Mouse
regulation of membrane repolarization GO:0060306 1 0.117
Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.115
camera type eye development GO:0043010 222 0.114
neuromast development GO:0048884 46 0.114
nerve development GO:0021675 45 0.112
regulation of signaling GO:0023051 235 0.112
retina development in camera type eye GO:0060041 146 0.110
metal ion transport GO:0030001 58 0.109
eye development GO:0001654 277 0.107
larval behavior GO:0030537 5 0.107
cellular component assembly involved in morphogenesis GO:0010927 107 0.107
cardiac conduction GO:0061337 3 0.106
Mouse
detection of light stimulus GO:0009583 12 0.101
sensory organ morphogenesis GO:0090596 200 0.098
regulation of cell differentiation GO:0045595 142 0.095
Mouse
regulation of biological quality GO:0065008 263 0.094
Mouse
cellular component assembly GO:0022607 170 0.094
cell morphogenesis involved in differentiation GO:0000904 195 0.092
Mouse
sensory perception GO:0007600 39 0.092
establishment of localization GO:0051234 244 0.090
signal transduction GO:0007165 455 0.090
larval development GO:0002164 2 0.088
regulation of ion transmembrane transport GO:0034765 18 0.088
regulation of membrane potential GO:0042391 23 0.086
Mouse
optic nerve development GO:0021554 15 0.083
phototransduction visible light GO:0007603 2 0.082
cell morphogenesis GO:0000902 289 0.080
Mouse
morphogenesis of an epithelium GO:0002009 333 0.080
central nervous system development GO:0007417 387 0.076
Mouse
forebrain cell migration GO:0021885 1 0.075
neural tube development GO:0021915 62 0.075
regulation of transmembrane transport GO:0034762 18 0.071
motor neuron axon guidance GO:0008045 23 0.070
regulation of response to cytokine stimulus GO:0060759 3 0.066
cellular response to radiation GO:0071478 4 0.066
epithelial tube morphogenesis GO:0060562 148 0.063
regulation of jak stat cascade GO:0046425 3 0.063
regulation of glial cell differentiation GO:0045685 4 0.063
regulation of macromolecule metabolic process GO:0060255 317 0.062
head development GO:0060322 303 0.061
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.061
response to chemical GO:0042221 320 0.060
Mouse
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.058
regulation of neuron migration GO:2001222 2 0.057
peripheral nervous system neuron differentiation GO:0048934 28 0.055
regulation of response to oxidative stress GO:1902882 2 0.055
g protein coupled receptor signaling pathway GO:0007186 74 0.054
cell part morphogenesis GO:0032990 246 0.052
Mouse
muscle structure development GO:0061061 196 0.052
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.052
regulation of blood circulation GO:1903522 32 0.051
Mouse
circulatory system process GO:0003013 87 0.049
Mouse
posterior lateral line system development GO:0048915 46 0.048
actomyosin structure organization GO:0031032 53 0.045
hair cell differentiation GO:0035315 32 0.043
response to light stimulus GO:0009416 46 0.042
visual perception GO:0007601 17 0.042
cell death GO:0008219 121 0.041
adherens junction maintenance GO:0034334 2 0.041
cellular component maintenance GO:0043954 3 0.040
muscle system process GO:0003012 20 0.040
neurological system process GO:0050877 62 0.040
Mouse
positive regulation of gliogenesis GO:0014015 2 0.040
single organism transport GO:0044765 206 0.039
regulation of cytokine production GO:0001817 3 0.039
negative regulation of neuron projection development GO:0010977 9 0.039
branching morphogenesis of a nerve GO:0048755 4 0.039
ion homeostasis GO:0050801 41 0.038
localization of cell GO:0051674 244 0.038
cell growth GO:0016049 57 0.038
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.038
establishment of cell polarity GO:0030010 18 0.038
tube morphogenesis GO:0035239 349 0.037
regulation of system process GO:0044057 40 0.037
Mouse
monovalent inorganic cation transport GO:0015672 42 0.037
brain development GO:0007420 293 0.037
regulation of localization GO:0032879 104 0.037
regulation of neurogenesis GO:0050767 87 0.036
Mouse
neuron apoptotic process GO:0051402 20 0.036
membrane repolarization GO:0086009 2 0.035
Mouse
single organism localization GO:1902578 225 0.035
cellular response to light stimulus GO:0071482 4 0.035
positive regulation of apoptotic signaling pathway GO:2001235 1 0.035
cellular component morphogenesis GO:0032989 336 0.035
Mouse
response to radiation GO:0009314 51 0.035
regulation of cellular response to oxidative stress GO:1900407 2 0.035
determination of left right symmetry GO:0007368 179 0.034
larval locomotory behavior GO:0008345 5 0.034
regulation of binding GO:0051098 3 0.034
sequestering of calcium ion GO:0051208 3 0.034
tyrosine phosphorylation of stat protein GO:0007260 1 0.034
chemotaxis GO:0006935 104 0.033
Mouse
cell death in response to oxidative stress GO:0036473 2 0.033
regulation of metal ion transport GO:0010959 4 0.033
regulation of synapse assembly GO:0051963 3 0.032
chemical homeostasis GO:0048878 49 0.032
neuron projection development GO:0031175 180 0.032
Mouse
regulation of protein binding GO:0043393 3 0.032
positive regulation of cytokine production GO:0001819 2 0.032
locomotory behavior GO:0007626 34 0.031
response to stress GO:0006950 263 0.031
response to oxygen containing compound GO:1901700 55 0.030
regulation of transport GO:0051049 45 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
outflow tract morphogenesis GO:0003151 1 0.030
positive regulation of glucose transport GO:0010828 1 0.030
intrinsic apoptotic signaling pathway GO:0097193 20 0.029
cell junction maintenance GO:0034331 2 0.029
determination of heart left right asymmetry GO:0061371 117 0.028
lipid storage GO:0019915 1 0.028
heart process GO:0003015 71 0.028
Mouse
camera type eye morphogenesis GO:0048593 108 0.028
glial cell proliferation GO:0014009 4 0.028
cranial nerve development GO:0021545 42 0.028
single organism organelle organization GO:1902589 199 0.028
leukocyte proliferation GO:0070661 1 0.027
determination of bilateral symmetry GO:0009855 204 0.027
retina morphogenesis in camera type eye GO:0060042 79 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
organelle assembly GO:0070925 110 0.026
organic hydroxy compound transport GO:0015850 14 0.026
cardiac myofibril assembly GO:0055003 9 0.026
oxoacid metabolic process GO:0043436 31 0.026
cell migration GO:0016477 237 0.025
sequestering of metal ion GO:0051238 3 0.025
axon guidance GO:0007411 86 0.025
Mouse
muscle hypertrophy GO:0014896 2 0.025
eye morphogenesis GO:0048592 144 0.025
response to wounding GO:0009611 116 0.024
neuron projection morphogenesis GO:0048812 161 0.024
Mouse
regulation of cytokine mediated signaling pathway GO:0001959 3 0.024
regulation of circadian rhythm GO:0042752 4 0.024
phototransduction GO:0007602 2 0.024
homeostatic process GO:0042592 142 0.024
striated muscle cell differentiation GO:0051146 129 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
muscle contraction GO:0006936 18 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
cellular amine metabolic process GO:0044106 2 0.023
striated muscle tissue development GO:0014706 110 0.023
cellular ketone metabolic process GO:0042180 11 0.023
response to hormone GO:0009725 48 0.023
posterior lateral line development GO:0048916 38 0.023
muscle cell development GO:0055001 115 0.023
negative regulation of metabolic process GO:0009892 86 0.023
antimicrobial humoral response GO:0019730 2 0.023
smooth muscle contraction GO:0006939 2 0.022
cilium organization GO:0044782 71 0.022
monoamine transport GO:0015844 1 0.022
axon ensheathment in central nervous system GO:0032291 2 0.022
regulation of developmental growth GO:0048638 38 0.022
peripheral nervous system development GO:0007422 55 0.021
protein dephosphorylation GO:0006470 3 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
response to uv GO:0009411 3 0.021
protein complex assembly GO:0006461 30 0.021
regulation of organelle assembly GO:1902115 4 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
negative regulation of cell projection organization GO:0031345 9 0.021
embryonic organ development GO:0048568 381 0.021
regeneration GO:0031099 91 0.021
negative regulation of neuron differentiation GO:0045665 10 0.021
regulation of neuron differentiation GO:0045664 56 0.021
Mouse
neuroblast proliferation GO:0007405 2 0.021
negative regulation of cytokine production GO:0001818 1 0.020
heart looping GO:0001947 94 0.020
photoreceptor cell development GO:0042461 40 0.020
embryonic heart tube development GO:0035050 133 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
glucose import GO:0046323 2 0.019
axon extension GO:0048675 45 0.019
regulation of primary metabolic process GO:0080090 311 0.019
regulation of dendrite development GO:0050773 3 0.019
posterior lateral line neuromast development GO:0048919 20 0.019
cell projection assembly GO:0030031 64 0.019
maintenance of location GO:0051235 4 0.018
cilium assembly GO:0042384 58 0.018
regulation of heart growth GO:0060420 2 0.018
response to lipid GO:0033993 60 0.018
lateral line development GO:0048882 66 0.018
specification of symmetry GO:0009799 204 0.018
muscle cell differentiation GO:0042692 139 0.018
autonomic nervous system development GO:0048483 19 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.017
single organism metabolic process GO:0044710 217 0.017
cellular chemical homeostasis GO:0055082 17 0.017
neurotransmitter transport GO:0006836 2 0.017
innervation GO:0060384 3 0.017
regulation of nervous system development GO:0051960 90 0.017
Mouse
sensory perception of pain GO:0019233 1 0.017
heart contraction GO:0060047 71 0.017
Mouse
regulation of response to stimulus GO:0048583 269 0.017
negative regulation of cellular process GO:0048523 283 0.017
light induced release of internally sequestered calcium ion GO:0008377 1 0.017
heterocycle metabolic process GO:0046483 290 0.017
organelle organization GO:0006996 227 0.017
light absorption GO:0016037 2 0.017
convergent extension GO:0060026 118 0.017
female gonad development GO:0008585 4 0.016
pigment cell development GO:0070285 3 0.016
circadian sleep wake cycle GO:0042745 2 0.016
growth GO:0040007 174 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
response to organic substance GO:0010033 153 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
embryonic skeletal joint development GO:0072498 3 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
cation homeostasis GO:0055080 33 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
cellular metal ion homeostasis GO:0006875 16 0.015
protein import GO:0017038 3 0.015
response to cold GO:0009409 4 0.015
positive regulation of glucose import GO:0046326 1 0.015
stem cell proliferation GO:0072089 4 0.015
amine metabolic process GO:0009308 2 0.015
regulation of anatomical structure size GO:0090066 33 0.015
response to arsenic containing substance GO:0046685 5 0.015
gene expression GO:0010467 252 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
establishment of blood brain barrier GO:0060856 2 0.015
adult behavior GO:0030534 2 0.015
sensory system development GO:0048880 76 0.015
neuron projection regeneration GO:0031102 16 0.015
eye photoreceptor cell differentiation GO:0001754 45 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
gliogenesis GO:0042063 45 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
inner ear receptor cell differentiation GO:0060113 29 0.015
long chain fatty acid metabolic process GO:0001676 1 0.014
rhodopsin mediated signaling pathway GO:0016056 1 0.014
neuron projection guidance GO:0097485 86 0.014
Mouse
positive regulation of developmental process GO:0051094 50 0.014
Mouse
divalent inorganic cation homeostasis GO:0072507 22 0.014
taxis GO:0042330 109 0.014
Mouse
protein metabolic process GO:0019538 183 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
lipid metabolic process GO:0006629 52 0.014
photoreceptor cell morphogenesis GO:0008594 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
regulation of leukocyte mediated immunity GO:0002703 1 0.014
angiogenesis GO:0001525 158 0.014
anatomical structure arrangement GO:0048532 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
amyloid precursor protein catabolic process GO:0042987 1 0.014
long chain fatty acid biosynthetic process GO:0042759 1 0.014
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
axis elongation involved in somitogenesis GO:0090245 2 0.013
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.013
striated muscle cell proliferation GO:0014855 7 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
muscle cell migration GO:0014812 4 0.013
triglyceride homeostasis GO:0070328 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
central nervous system myelination GO:0022010 2 0.013
muscle tissue development GO:0060537 110 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
sarcomere organization GO:0045214 26 0.013
membrane hyperpolarization GO:0060081 1 0.013
central nervous system neuron differentiation GO:0021953 74 0.013
Mouse
gamma aminobutyric acid signaling pathway GO:0007214 1 0.013
peripheral nervous system neuron development GO:0048935 22 0.012
positive regulation of blood circulation GO:1903524 2 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
biosynthetic process GO:0009058 294 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
directional locomotion GO:0033058 1 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
positive regulation of heart contraction GO:0045823 2 0.012
immune system process GO:0002376 241 0.012
response to drug GO:0042493 3 0.012
sensory perception of light stimulus GO:0050953 19 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
response to glucocorticoid GO:0051384 1 0.012
response to osmotic stress GO:0006970 11 0.012
synaptic vesicle transport GO:0048489 1 0.012
peptidyl tyrosine dephosphorylation GO:0035335 1 0.012
regulation of cellular component movement GO:0051270 55 0.012
rhythmic process GO:0048511 21 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
Mouse
response to topologically incorrect protein GO:0035966 2 0.012
multi organism process GO:0051704 134 0.012
nitric oxide metabolic process GO:0046209 2 0.012
actin filament based process GO:0030029 64 0.012
inner ear receptor stereocilium organization GO:0060122 8 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
developmental growth GO:0048589 166 0.011
mitochondrion organization GO:0007005 4 0.011
transport GO:0006810 220 0.011
response to organic cyclic compound GO:0014070 51 0.011
synaptic vesicle localization GO:0097479 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of cell death GO:0010941 103 0.011
pronephros development GO:0048793 69 0.011
establishment or maintenance of cell polarity GO:0007163 29 0.011
protein complex biogenesis GO:0070271 30 0.011
digestive tract development GO:0048565 265 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
death GO:0016265 121 0.011
regulation of locomotion GO:0040012 55 0.011
regulation of transporter activity GO:0032409 2 0.011
positive regulation of transport GO:0051050 2 0.011
positive regulation of glial cell proliferation GO:0060252 1 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.011
regulation of cell activation GO:0050865 1 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of heart contraction GO:0008016 32 0.011
Mouse
developmental cell growth GO:0048588 52 0.011
activation of immune response GO:0002253 9 0.011
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.011
Mouse
negative regulation of cell migration GO:0030336 17 0.011
regulation of sarcomere organization GO:0060297 2 0.011
negative regulation of cell motility GO:2000146 17 0.011
cellular response to organic substance GO:0071310 105 0.011
glial cell migration GO:0008347 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
cardiac muscle cell differentiation GO:0055007 30 0.010
positive regulation of metabolic process GO:0009893 108 0.010
regulation of synapse organization GO:0050807 3 0.010
cytoskeleton organization GO:0007010 96 0.010
carbon dioxide transport GO:0015670 3 0.010
cardiac muscle tissue development GO:0048738 48 0.010
actin cytoskeleton organization GO:0030036 63 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010

scn1ba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
heart disease DOID:114 0 0.013
cardiovascular system disease DOID:1287 0 0.013