Danio rerio

0 known processes

wdr35

WD repeat domain 35

(Aliases: si:ch211-206k20.4,im:7159945)

wdr35 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.083
aging GO:0007568 2 0.080
cell projection organization GO:0030030 284 0.040
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.039
cell projection morphogenesis GO:0048858 244 0.037
Human Mouse
multicellular organism growth GO:0035264 4 0.037
positive regulation of catabolic process GO:0009896 4 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.036
gtp metabolic process GO:0046039 4 0.036
heterocycle metabolic process GO:0046483 290 0.035
regulation of metabolic process GO:0019222 359 0.035
cellular component morphogenesis GO:0032989 336 0.034
Human Mouse
mitochondrion organization GO:0007005 4 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
guanosine containing compound metabolic process GO:1901068 4 0.034
cellular macromolecule metabolic process GO:0044260 391 0.034
cognition GO:0050890 1 0.034
cell morphogenesis GO:0000902 289 0.033
Human Mouse
guanosine containing compound catabolic process GO:1901069 2 0.033
gtp catabolic process GO:0006184 2 0.033
phagocytosis GO:0006909 3 0.032
adult behavior GO:0030534 2 0.032
positive regulation of transport GO:0051050 2 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
organelle fusion GO:0048284 3 0.030
ribonucleoside monophosphate catabolic process GO:0009158 4 0.030
maintenance of location GO:0051235 4 0.029
amine metabolic process GO:0009308 2 0.029
cellular amine metabolic process GO:0044106 2 0.028
protein localization to nucleus GO:0034504 3 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
purine nucleoside monophosphate catabolic process GO:0009128 4 0.028
nucleoside monophosphate catabolic process GO:0009125 4 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
membrane fusion GO:0061025 2 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.027
atp catabolic process GO:0006200 4 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of biological quality GO:0065008 263 0.027
single organism organelle organization GO:1902589 199 0.026
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.026
regulation of synapse organization GO:0050807 3 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
signal transduction GO:0007165 455 0.026
rna metabolic process GO:0016070 219 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.025
single organism membrane fusion GO:0044801 2 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
generation of neurons GO:0048699 385 0.025
cellular component movement GO:0006928 335 0.025
Human
regulation of nucleoside metabolic process GO:0009118 2 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
protein targeting to nucleus GO:0044744 3 0.024
regulation of protein transport GO:0051223 3 0.024
nuclear import GO:0051170 3 0.024
cell part morphogenesis GO:0032990 246 0.024
Human Mouse
single organism metabolic process GO:0044710 217 0.024
exocytosis GO:0006887 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
single organism nuclear import GO:1902593 3 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
nuclear transport GO:0051169 4 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
protein import into nucleus GO:0006606 3 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
positive regulation of cell cycle GO:0045787 3 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
cellular protein catabolic process GO:0044257 4 0.022
regulation of cell communication GO:0010646 232 0.022
neuron differentiation GO:0030182 353 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
embryonic organ development GO:0048568 381 0.022
regulation of response to stimulus GO:0048583 269 0.022
transport GO:0006810 220 0.022
Human
biosynthetic process GO:0009058 294 0.022
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
autophagy GO:0006914 4 0.022
gene expression GO:0010467 252 0.022
regulation of gene expression GO:0010468 265 0.022
regulation of signaling GO:0023051 235 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of establishment of protein localization GO:0070201 4 0.021
protein import GO:0017038 3 0.021
regulation of primary metabolic process GO:0080090 311 0.021
regulation of cell shape GO:0008360 1 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
locomotion GO:0040011 313 0.021
peptidyl serine modification GO:0018209 2 0.021
organic substance biosynthetic process GO:1901576 289 0.021
cellular component biogenesis GO:0044085 178 0.021
Human Mouse
neurotransmitter transport GO:0006836 2 0.021
stem cell proliferation GO:0072089 4 0.020
response to chemical GO:0042221 320 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of signal transduction GO:0009966 225 0.020
neurotransmitter secretion GO:0007269 2 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
small molecule metabolic process GO:0044281 77 0.020
organelle organization GO:0006996 227 0.020
Human Mouse
rna localization GO:0006403 4 0.020
meiotic nuclear division GO:0007126 4 0.020
cilium assembly GO:0042384 58 0.019
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.019
stem cell maintenance GO:0019827 4 0.019
endosomal transport GO:0016197 2 0.019
sensory organ development GO:0007423 393 0.019
synaptic vesicle transport GO:0048489 1 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
regulation of synapse assembly GO:0051963 3 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
cellular response to nutrient levels GO:0031669 2 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of cytokine production GO:0001817 3 0.019
nucleic acid metabolic process GO:0090304 244 0.019
neuron development GO:0048666 262 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cell migration GO:0016477 237 0.019
neuron projection morphogenesis GO:0048812 161 0.019
transcription dna templated GO:0006351 181 0.018
single organism localization GO:1902578 225 0.018
Human
centrosome cycle GO:0007098 1 0.018
axon development GO:0061564 166 0.018
negative regulation of biological process GO:0048519 304 0.018
cellular amide metabolic process GO:0043603 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
compound eye development GO:0048749 2 0.018
cellular ketone metabolic process GO:0042180 11 0.018
positive regulation of secretion GO:0051047 1 0.018
cell substrate adhesion GO:0031589 4 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
digestive system development GO:0055123 289 0.018
cytokinesis GO:0000910 3 0.018
cell matrix adhesion GO:0007160 4 0.018
cellular biosynthetic process GO:0044249 286 0.018
oxoacid metabolic process GO:0043436 31 0.018
organic acid metabolic process GO:0006082 31 0.018
proteasomal protein catabolic process GO:0010498 2 0.017
growth GO:0040007 174 0.017
cellular component assembly GO:0022607 170 0.017
Human Mouse
regulation of neurotransmitter transport GO:0051588 1 0.017
tube morphogenesis GO:0035239 349 0.017
regulation of protein complex assembly GO:0043254 3 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of reproductive process GO:2000241 4 0.017
system process GO:0003008 185 0.017
establishment of localization GO:0051234 244 0.017
Human
regulation of protein catabolic process GO:0042176 1 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
post embryonic organ development GO:0048569 4 0.017
protein metabolic process GO:0019538 183 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
secondary metabolic process GO:0019748 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cellular response to starvation GO:0009267 1 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
response to drug GO:0042493 3 0.017
localization of cell GO:0051674 244 0.017
regulation of binding GO:0051098 3 0.016
organelle assembly GO:0070925 110 0.016
Human Mouse
lipid storage GO:0019915 1 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
neuroblast proliferation GO:0007405 2 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
response to external stimulus GO:0009605 264 0.016
muscle structure development GO:0061061 196 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of gtpase activity GO:0043087 2 0.016
glucose homeostasis GO:0042593 1 0.016
axonogenesis GO:0007409 152 0.016
gastrulation GO:0007369 208 0.016
negative regulation of kinase activity GO:0033673 4 0.016
response to topologically incorrect protein GO:0035966 2 0.016
positive regulation of cellular process GO:0048522 201 0.016
golgi vesicle transport GO:0048193 3 0.016
eye development GO:0001654 277 0.015
tissue remodeling GO:0048771 4 0.015
response to stress GO:0006950 263 0.015
membrane invagination GO:0010324 1 0.015
meiotic cell cycle process GO:1903046 3 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
Human Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
muscle cell differentiation GO:0042692 139 0.015
regulation of jak stat cascade GO:0046425 3 0.015
regulation of developmental process GO:0050793 247 0.015
digestive tract development GO:0048565 265 0.015
locomotor rhythm GO:0045475 3 0.015
chemosensory behavior GO:0007635 1 0.015
response to monosaccharide GO:0034284 3 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
protein acetylation GO:0006473 2 0.015
macromolecule modification GO:0043412 111 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
negative regulation of cellular process GO:0048523 283 0.014
response to carbohydrate GO:0009743 3 0.014
lateral inhibition GO:0046331 1 0.014
single organism transport GO:0044765 206 0.014
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
cilium organization GO:0044782 71 0.014
Human Mouse
centrosome organization GO:0051297 1 0.014
cilium morphogenesis GO:0060271 85 0.014
Human Mouse
phagocytosis engulfment GO:0006911 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
determination of bilateral symmetry GO:0009855 204 0.014
chordate embryonic development GO:0043009 271 0.014
primary neural tube formation GO:0014020 1 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of biosynthetic process GO:0009889 250 0.014
hemopoiesis GO:0030097 183 0.014
camera type eye development GO:0043010 222 0.014
phosphorus metabolic process GO:0006793 109 0.014
nucleic acid templated transcription GO:0097659 181 0.014
macroautophagy GO:0016236 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
protein complex disassembly GO:0043241 1 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
synaptic vesicle localization GO:0097479 1 0.013
immune system process GO:0002376 241 0.013
response to hexose GO:0009746 3 0.013
regionalization GO:0003002 274 0.013
protein dephosphorylation GO:0006470 3 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of cell activation GO:0050865 1 0.013
developmental growth GO:0048589 166 0.013
digestive tract morphogenesis GO:0048546 231 0.013
pigment granule localization GO:0051875 25 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
response to uv GO:0009411 3 0.013
protein homooligomerization GO:0051260 3 0.013
negative regulation of protein transport GO:0051224 3 0.013
developmental programmed cell death GO:0010623 4 0.013
homeostatic process GO:0042592 142 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
spermatid development GO:0007286 2 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
cellular component disassembly GO:0022411 1 0.012
sequestering of metal ion GO:0051238 3 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
specification of symmetry GO:0009799 204 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
cellular protein modification process GO:0006464 100 0.012
protein localization to plasma membrane GO:0072659 1 0.012
protein polyubiquitination GO:0000209 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cell motility GO:0048870 244 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
nucleic acid transport GO:0050657 2 0.012
neuron projection development GO:0031175 180 0.012
lipid catabolic process GO:0016042 4 0.012
cell projection assembly GO:0030031 64 0.012
Human Mouse
muscle cell development GO:0055001 115 0.012
regulation of transporter activity GO:0032409 2 0.012
somatic muscle development GO:0007525 4 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
response to glucose GO:0009749 3 0.012
adherens junction organization GO:0034332 4 0.012
regulation of exocytosis GO:0017157 1 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
striated muscle cell differentiation GO:0051146 129 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
striated muscle cell development GO:0055002 108 0.011
rna biosynthetic process GO:0032774 181 0.011
interspecies interaction between organisms GO:0044419 4 0.011
response to organic substance GO:0010033 153 0.011
sensory organ morphogenesis GO:0090596 200 0.011
positive regulation of metabolic process GO:0009893 108 0.011
ameboidal type cell migration GO:0001667 143 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
viral process GO:0016032 1 0.011
peptide transport GO:0015833 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of cell differentiation GO:0045595 142 0.011
negative regulation of signaling GO:0023057 96 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
establishment of localization in cell GO:0051649 77 0.011
Human
alcohol biosynthetic process GO:0046165 2 0.011
head development GO:0060322 303 0.011
stem cell division GO:0017145 1 0.011
regulation of mrna processing GO:0050684 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
mitochondrial transport GO:0006839 2 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
spermatid differentiation GO:0048515 2 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
vasculature development GO:0001944 278 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
cellular response to radiation GO:0071478 4 0.011
regulation of transcription dna templated GO:0006355 213 0.011
apoptotic process involved in development GO:1902742 2 0.011
regulation of calcium ion transport GO:0051924 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
macromolecular complex disassembly GO:0032984 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
tube closure GO:0060606 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
dicarboxylic acid transport GO:0006835 1 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
heart development GO:0007507 313 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
neurological system process GO:0050877 62 0.010
actin filament polymerization GO:0030041 2 0.010
peptide metabolic process GO:0006518 1 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
intracellular mrna localization GO:0008298 1 0.010
central nervous system development GO:0007417 387 0.010
ras protein signal transduction GO:0007265 7 0.010
negative regulation of defense response GO:0031348 2 0.010
organism emergence from protective structure GO:0071684 4 0.010
blood vessel development GO:0001568 246 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of reproductive process GO:2000242 3 0.010
multicellular organismal signaling GO:0035637 22 0.010
cellular localization GO:0051641 97 0.010
Human
cellular response to biotic stimulus GO:0071216 3 0.010
wnt signaling pathway GO:0016055 80 0.010
regulation of cellular component organization GO:0051128 86 0.010
protein stabilization GO:0050821 2 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010

wdr35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.011