Danio rerio

0 known processes

glulb

glutamate-ammonia ligase (glutamine synthase) b

(Aliases: hm:zehn1949,gso2,wu:fb11d08,im:7153900,fb11d08)

glulb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid biosynthetic process GO:0008652 2 0.361
transport GO:0006810 220 0.304
Fly
regulation of metabolic process GO:0019222 359 0.282
gene expression GO:0010467 252 0.251
regulation of cellular metabolic process GO:0031323 320 0.240
single organism transport GO:0044765 206 0.222
Fly
macromolecule biosynthetic process GO:0009059 227 0.216
mechanosensory lateral line system development GO:0048881 49 0.214
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.195
establishment of localization GO:0051234 244 0.146
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.132
response to antibiotic GO:0046677 1 0.126
nucleobase containing compound metabolic process GO:0006139 274 0.122
single organism metabolic process GO:0044710 217 0.122
Fly
negative regulation of biological process GO:0048519 304 0.120
homeostatic process GO:0042592 142 0.115
hematopoietic or lymphoid organ development GO:0048534 191 0.113
cellular aromatic compound metabolic process GO:0006725 295 0.109
response to biotic stimulus GO:0009607 97 0.108
regulation of macromolecule metabolic process GO:0060255 317 0.107
nitrogen compound transport GO:0071705 23 0.107
regulation of metal ion transport GO:0010959 4 0.104
dicarboxylic acid metabolic process GO:0043648 1 0.099
regulation of cellular biosynthetic process GO:0031326 245 0.096
organic cyclic compound biosynthetic process GO:1901362 223 0.095
positive regulation of cellular process GO:0048522 201 0.092
nucleocytoplasmic transport GO:0006913 4 0.092
organic cyclic compound metabolic process GO:1901360 301 0.088
signal transduction GO:0007165 455 0.086
cellular biosynthetic process GO:0044249 286 0.085
regulation of carbohydrate metabolic process GO:0006109 4 0.085
ubiquitin dependent protein catabolic process GO:0006511 3 0.085
cellular nitrogen compound metabolic process GO:0034641 290 0.082
peptide transport GO:0015833 1 0.081
erythrocyte differentiation GO:0030218 54 0.080
modification dependent protein catabolic process GO:0019941 3 0.079
positive regulation of transport GO:0051050 2 0.078
regulation of mrna splicing via spliceosome GO:0048024 3 0.077
regulation of nitrogen compound metabolic process GO:0051171 251 0.074
chemical homeostasis GO:0048878 49 0.073
hemopoiesis GO:0030097 183 0.072
immune system development GO:0002520 191 0.072
cellular modified amino acid metabolic process GO:0006575 3 0.070
sensory system development GO:0048880 76 0.069
hormone secretion GO:0046879 2 0.069
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.069
cellular macromolecule metabolic process GO:0044260 391 0.069
transcription dna templated GO:0006351 181 0.068
protein metabolic process GO:0019538 183 0.067
regulation of sodium ion transport GO:0002028 2 0.067
regulation of nucleocytoplasmic transport GO:0046822 2 0.066
nuclear transport GO:0051169 4 0.064
heterocycle biosynthetic process GO:0018130 215 0.063
nitrogen compound metabolic process GO:0006807 319 0.063
Fly
positive regulation of biological process GO:0048518 253 0.062
ameboidal type cell migration GO:0001667 143 0.062
transcription from rna polymerase ii promoter GO:0006366 80 0.062
regulation of primary metabolic process GO:0080090 311 0.061
regulation of gene expression GO:0010468 265 0.061
cellular carbohydrate metabolic process GO:0044262 4 0.061
positive regulation of cellular catabolic process GO:0031331 3 0.060
lateral line system development GO:0048925 76 0.059
establishment of protein localization to organelle GO:0072594 4 0.059
response to external biotic stimulus GO:0043207 97 0.058
response to other organism GO:0051707 97 0.058
cellular macromolecule biosynthetic process GO:0034645 224 0.057
amide transport GO:0042886 12 0.057
response to external stimulus GO:0009605 264 0.056
Mouse
organic substance biosynthetic process GO:1901576 289 0.056
single organism localization GO:1902578 225 0.055
Fly
cellular amide metabolic process GO:0043603 4 0.054
eye development GO:0001654 277 0.053
organonitrogen compound metabolic process GO:1901564 74 0.053
Fly
sensory organ development GO:0007423 393 0.052
locomotion GO:0040011 313 0.052
embryonic hemopoiesis GO:0035162 53 0.052
establishment of rna localization GO:0051236 3 0.052
regulation of localization GO:0032879 104 0.052
hormone transport GO:0009914 2 0.051
cell surface receptor signaling pathway GO:0007166 325 0.050
lateral line development GO:0048882 66 0.049
cellular sodium ion homeostasis GO:0006883 1 0.049
system process GO:0003008 185 0.049
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.048
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.047
negative regulation of cytoplasmic transport GO:1903650 2 0.047
response to glucocorticoid GO:0051384 1 0.047
biosynthetic process GO:0009058 294 0.046
digestive tract development GO:0048565 265 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
response to drug GO:0042493 3 0.044
regulation of biological quality GO:0065008 263 0.044
regulation of biosynthetic process GO:0009889 250 0.043
regulation of signal transduction GO:0009966 225 0.043
pole plasm assembly GO:0007315 4 0.043
modification dependent macromolecule catabolic process GO:0043632 3 0.043
cellular response to biotic stimulus GO:0071216 3 0.043
aging GO:0007568 2 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
oxoacid metabolic process GO:0043436 31 0.042
Fly
cellular amino acid metabolic process GO:0006520 7 0.042
Fly
regulation of rna metabolic process GO:0051252 224 0.042
response to corticosteroid GO:0031960 1 0.041
positive regulation of secretion by cell GO:1903532 1 0.041
cellular response to oxygen levels GO:0071453 1 0.040
regulation of response to stimulus GO:0048583 269 0.039
cellular component movement GO:0006928 335 0.038
response to carbohydrate GO:0009743 3 0.038
Mouse
anion transport GO:0006820 38 0.038
positive regulation of carbohydrate metabolic process GO:0045913 1 0.038
carbohydrate homeostasis GO:0033500 1 0.037
embryonic organ development GO:0048568 381 0.037
stem cell maintenance GO:0019827 4 0.037
response to chemical GO:0042221 320 0.037
Mouse
positive regulation of cell cycle GO:0045787 3 0.037
cellular response to decreased oxygen levels GO:0036294 1 0.036
alternative mrna splicing via spliceosome GO:0000380 1 0.036
cytoplasm organization GO:0007028 4 0.036
dorsal ventral pattern formation GO:0009953 125 0.035
positive regulation of nucleoside metabolic process GO:0045979 1 0.035
protein localization to nucleus GO:0034504 3 0.035
negative regulation of cellular process GO:0048523 283 0.034
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.034
heterocycle metabolic process GO:0046483 290 0.034
head development GO:0060322 303 0.034
cellular response to hypoxia GO:0071456 1 0.033
positive regulation of secretion GO:0051047 1 0.033
cellular protein catabolic process GO:0044257 4 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
negative regulation of protein localization to nucleus GO:1900181 2 0.033
negative regulation of intracellular transport GO:0032387 3 0.033
interaction with host GO:0051701 4 0.033
fin morphogenesis GO:0033334 53 0.032
apoptotic process GO:0006915 116 0.032
regulation of mrna processing GO:0050684 3 0.032
mitochondrion organization GO:0007005 4 0.032
Fly
kidney development GO:0001822 92 0.032
brain development GO:0007420 293 0.032
cell cycle g1 s phase transition GO:0044843 1 0.031
cellular iron ion homeostasis GO:0006879 3 0.031
regulation of cell communication GO:0010646 232 0.030
phosphate containing compound metabolic process GO:0006796 108 0.030
posterior lateral line development GO:0048916 38 0.029
response to monosaccharide GO:0034284 3 0.029
Mouse
alpha amino acid metabolic process GO:1901605 3 0.029
Fly
cell death GO:0008219 121 0.028
lipid storage GO:0019915 1 0.028
cellular localization GO:0051641 97 0.028
hydrogen peroxide metabolic process GO:0042743 2 0.027
neuromast development GO:0048884 46 0.027
positive regulation of catabolic process GO:0009896 4 0.027
erythrocyte maturation GO:0043249 8 0.027
gtp catabolic process GO:0006184 2 0.027
gtp metabolic process GO:0046039 4 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.026
negative regulation of response to dna damage stimulus GO:2001021 3 0.026
tube morphogenesis GO:0035239 349 0.026
cellular response to lipid GO:0071396 39 0.026
dicarboxylic acid transport GO:0006835 1 0.026
cellular response to lipopolysaccharide GO:0071222 3 0.026
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
peptide metabolic process GO:0006518 1 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
nucleobase containing compound transport GO:0015931 2 0.025
rna localization GO:0006403 4 0.025
camera type eye development GO:0043010 222 0.025
cellular response to external stimulus GO:0071496 2 0.025
Mouse
translational initiation GO:0006413 3 0.024
cellular response to nutrient levels GO:0031669 2 0.024
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.024
single organism biosynthetic process GO:0044711 71 0.024
protein import GO:0017038 3 0.024
rna export from nucleus GO:0006405 1 0.024
protein polyubiquitination GO:0000209 4 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
eye morphogenesis GO:0048592 144 0.023
response to endogenous stimulus GO:0009719 83 0.023
regulation of translational initiation GO:0006446 1 0.023
cellular component biogenesis GO:0044085 178 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
Fly
response to hexose GO:0009746 3 0.022
Mouse
erythrocyte homeostasis GO:0034101 55 0.022
nuclear export GO:0051168 1 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
negative regulation of map kinase activity GO:0043407 2 0.022
regulation of binding GO:0051098 3 0.022
3 utr mediated mrna stabilization GO:0070935 3 0.022
sodium ion transport GO:0006814 24 0.022
iron ion homeostasis GO:0055072 4 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
regulation of intracellular protein transport GO:0033157 3 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
regulation of production of molecular mediator of immune response GO:0002700 1 0.021
spindle assembly involved in meiosis GO:0090306 1 0.021
response to stress GO:0006950 263 0.021
Mouse
cellular transition metal ion homeostasis GO:0046916 3 0.021
protein polymerization GO:0051258 4 0.021
regulation of apoptotic process GO:0042981 98 0.021
regulation of protein metabolic process GO:0051246 56 0.020
blood vessel development GO:0001568 246 0.020
ion transmembrane transport GO:0034220 91 0.020
pancreas development GO:0031016 84 0.020
peptidyl serine modification GO:0018209 2 0.020
protein modification process GO:0036211 100 0.020
signal transduction in absence of ligand GO:0038034 1 0.020
rna transport GO:0050658 2 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of transport GO:0051049 45 0.020
cofactor metabolic process GO:0051186 15 0.020
cellular protein metabolic process GO:0044267 129 0.020
positive regulation of metabolic process GO:0009893 108 0.020
protein dephosphorylation GO:0006470 3 0.019
digestive system development GO:0055123 289 0.019
cellular response to antibiotic GO:0071236 1 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
regulation of hormone secretion GO:0046883 2 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
organelle organization GO:0006996 227 0.018
Fly
posterior lateral line system development GO:0048915 46 0.018
amine metabolic process GO:0009308 2 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.018
spindle organization GO:0007051 5 0.018
regulation of hormone levels GO:0010817 21 0.018
rna metabolic process GO:0016070 219 0.018
forebrain development GO:0030900 96 0.018
protein localization to plasma membrane GO:0072659 1 0.018
heart looping GO:0001947 94 0.018
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
death GO:0016265 121 0.017
nucleic acid transport GO:0050657 2 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
central nervous system development GO:0007417 387 0.017
regulation of cytokine production GO:0001817 3 0.017
negative regulation of ras protein signal transduction GO:0046580 1 0.017
regulation of programmed cell death GO:0043067 101 0.017
meiotic cell cycle process GO:1903046 3 0.017
b cell activation GO:0042113 2 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
immune system process GO:0002376 241 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of transcription dna templated GO:0006355 213 0.017
negative regulation of cell death GO:0060548 60 0.016
multi organism cellular process GO:0044764 2 0.016
maintenance of location GO:0051235 4 0.016
digestive tract morphogenesis GO:0048546 231 0.016
female gonad development GO:0008585 4 0.016
nuclear import GO:0051170 3 0.016
tissue homeostasis GO:0001894 25 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
regulation of signaling GO:0023051 235 0.016
monovalent inorganic cation transport GO:0015672 42 0.016
response to amino acid GO:0043200 2 0.016
cation homeostasis GO:0055080 33 0.016
ion homeostasis GO:0050801 41 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
response to organic substance GO:0010033 153 0.016
Mouse
negative regulation of myeloid cell differentiation GO:0045638 1 0.016
gastrulation with mouth forming second GO:0001702 44 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
cellular response to organic substance GO:0071310 105 0.015
digestive system process GO:0022600 9 0.015
response to abiotic stimulus GO:0009628 122 0.015
cellular catabolic process GO:0044248 27 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
modulation by virus of host morphology or physiology GO:0019048 1 0.015
macrophage chemotaxis GO:0048246 3 0.015
vasculature development GO:0001944 278 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
proteolysis GO:0006508 38 0.014
glucose homeostasis GO:0042593 1 0.014
response to glucose GO:0009749 3 0.014
Mouse
startle response GO:0001964 4 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
phagocytosis GO:0006909 3 0.014
Fly
amide biosynthetic process GO:0043604 1 0.014
gastrulation GO:0007369 208 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
neuromast hair cell differentiation GO:0048886 12 0.014
single organism nuclear import GO:1902593 3 0.014
neurological system process GO:0050877 62 0.014
response to molecule of bacterial origin GO:0002237 14 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
organic acid metabolic process GO:0006082 31 0.013
Fly
positive regulation of cell substrate adhesion GO:0010811 1 0.013
meiotic chromosome segregation GO:0045132 3 0.013
protein targeting to membrane GO:0006612 1 0.013
energy reserve metabolic process GO:0006112 2 0.013
positive regulation of signaling GO:0023056 56 0.013
negative regulation of leukocyte differentiation GO:1902106 1 0.013
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.013
positive regulation of multi organism process GO:0043902 3 0.013
sequestering of calcium ion GO:0051208 3 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
organic substance transport GO:0071702 58 0.013
endodermal digestive tract morphogenesis GO:0061031 2 0.013
intracellular transport GO:0046907 32 0.013
small molecule catabolic process GO:0044282 3 0.013
nucleic acid metabolic process GO:0090304 244 0.013
mrna stabilization GO:0048255 4 0.013
regulation of blood pressure GO:0008217 1 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
response to uv GO:0009411 3 0.013
embryonic heart tube development GO:0035050 133 0.013
cellular ketone metabolic process GO:0042180 11 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
response to oxygen levels GO:0070482 25 0.012
astrocyte differentiation GO:0048708 1 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of locomotion GO:0040012 55 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
protein targeting to nucleus GO:0044744 3 0.012
gene silencing GO:0016458 4 0.012
spermatid differentiation GO:0048515 2 0.012
metal ion transport GO:0030001 58 0.012
mitochondrial transport GO:0006839 2 0.012
cellular protein modification process GO:0006464 100 0.012
regulation of protein complex assembly GO:0043254 3 0.012
peptidyl threonine modification GO:0018210 1 0.012
regulation of cell activation GO:0050865 1 0.012
cell migration GO:0016477 237 0.012
catabolic process GO:0009056 32 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
exocytosis GO:0006887 1 0.011
transmembrane transport GO:0055085 120 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
atp catabolic process GO:0006200 4 0.011
negative regulation of oocyte development GO:0060283 2 0.011
regulation of ion transmembrane transport GO:0034765 18 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
connective tissue development GO:0061448 99 0.011
cellular component maintenance GO:0043954 3 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
myeloid cell differentiation GO:0030099 86 0.011
female meiotic division GO:0007143 2 0.011
fin development GO:0033333 77 0.011
regulation of molecular function GO:0065009 70 0.011
rna stabilization GO:0043489 4 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
calcium mediated signaling GO:0019722 2 0.011
toxin transport GO:1901998 2 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
cytokinesis GO:0000910 3 0.011
b cell mediated immunity GO:0019724 3 0.011
growth GO:0040007 174 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
ectodermal cell fate specification GO:0001715 2 0.011
determination of bilateral symmetry GO:0009855 204 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
programmed cell death GO:0012501 119 0.011
negative regulation of programmed cell death GO:0043069 58 0.010
response to bacterium GO:0009617 58 0.010
small molecule biosynthetic process GO:0044283 16 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
macromolecule modification GO:0043412 111 0.010
macromolecular complex disassembly GO:0032984 1 0.010
cation transport GO:0006812 81 0.010
cellular response to steroid hormone stimulus GO:0071383 31 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
osteoclast differentiation GO:0030316 1 0.010
membrane repolarization GO:0086009 2 0.010
intracellular mrna localization GO:0008298 1 0.010
lipid homeostasis GO:0055088 3 0.010

glulb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
inherited metabolic disorder DOID:655 0 0.022
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
hematopoietic system disease DOID:74 0 0.013