Danio rerio

0 known processes

brn1.2

brain POU domain gene 1.2

(Aliases: id:ibd5088,brn-1.2)

brn1.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of macromolecule metabolic process GO:0060255 317 0.063
regulation of macromolecule biosynthetic process GO:0010556 225 0.059
positive regulation of transport GO:0051050 2 0.058
rna biosynthetic process GO:0032774 181 0.057
embryonic organ morphogenesis GO:0048562 274 0.056
regulation of biosynthetic process GO:0009889 250 0.055
regulation of nitrogen compound metabolic process GO:0051171 251 0.055
head development GO:0060322 303 0.053
regulation of biological quality GO:0065008 263 0.052
larval development GO:0002164 2 0.051
nucleic acid metabolic process GO:0090304 244 0.051
signal transduction GO:0007165 455 0.050
embryonic organ development GO:0048568 381 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.048
brain development GO:0007420 293 0.048
central nervous system development GO:0007417 387 0.048
aging GO:0007568 2 0.047
regulation of gene expression GO:0010468 265 0.046
stem cell maintenance GO:0019827 4 0.045
morphogenesis of an epithelium GO:0002009 333 0.045
regulation of nucleic acid templated transcription GO:1903506 213 0.045
cellular macromolecule metabolic process GO:0044260 391 0.044
gene expression GO:0010467 252 0.041
nucleic acid templated transcription GO:0097659 181 0.041
maintenance of location GO:0051235 4 0.041
organic cyclic compound metabolic process GO:1901360 301 0.041
aromatic compound biosynthetic process GO:0019438 217 0.041
regulation of metabolic process GO:0019222 359 0.041
neuron differentiation GO:0030182 353 0.040
cell surface receptor signaling pathway GO:0007166 325 0.039
cellular amine metabolic process GO:0044106 2 0.039
nitrogen compound metabolic process GO:0006807 319 0.039
sensory organ development GO:0007423 393 0.038
regulation of cytokine production GO:0001817 3 0.038
regulation of synapse assembly GO:0051963 3 0.037
tube morphogenesis GO:0035239 349 0.037
regulation of transcription dna templated GO:0006355 213 0.037
specification of symmetry GO:0009799 204 0.037
amine metabolic process GO:0009308 2 0.036
regulation of cellular metabolic process GO:0031323 320 0.036
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
regulation of response to stimulus GO:0048583 269 0.035
transcription dna templated GO:0006351 181 0.035
biosynthetic process GO:0009058 294 0.035
anterior posterior pattern specification GO:0009952 152 0.034
muscle structure development GO:0061061 196 0.033
sensory organ morphogenesis GO:0090596 200 0.033
cell projection organization GO:0030030 284 0.033
regulation of rna metabolic process GO:0051252 224 0.032
modification dependent protein catabolic process GO:0019941 3 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.032
chemotaxis GO:0006935 104 0.032
heterocycle metabolic process GO:0046483 290 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
cellular component assembly GO:0022607 170 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
cellular biosynthetic process GO:0044249 286 0.031
chordate embryonic development GO:0043009 271 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
locomotion GO:0040011 313 0.030
immune system process GO:0002376 241 0.030
generation of neurons GO:0048699 385 0.030
regionalization GO:0003002 274 0.029
regulation of primary metabolic process GO:0080090 311 0.029
cellular component movement GO:0006928 335 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
neuron development GO:0048666 262 0.028
determination of bilateral symmetry GO:0009855 204 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
proteasomal protein catabolic process GO:0010498 2 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
positive regulation of cellular process GO:0048522 201 0.027
cognition GO:0050890 1 0.027
multicellular organism growth GO:0035264 4 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
eye development GO:0001654 277 0.027
taxis GO:0042330 109 0.027
axon guidance GO:0007411 86 0.027
cellular protein catabolic process GO:0044257 4 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
positive regulation of biological process GO:0048518 253 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
cell projection morphogenesis GO:0048858 244 0.025
response to chemical GO:0042221 320 0.025
negative regulation of cellular process GO:0048523 283 0.024
cortical actin cytoskeleton organization GO:0030866 1 0.024
single organism nuclear import GO:1902593 3 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
cell motility GO:0048870 244 0.024
synaptic target recognition GO:0008039 1 0.024
cell morphogenesis GO:0000902 289 0.024
adult behavior GO:0030534 2 0.024
positive regulation of cytokine production GO:0001819 2 0.023
organic substance biosynthetic process GO:1901576 289 0.023
organelle organization GO:0006996 227 0.023
regulation of cell activation GO:0050865 1 0.023
digestive system development GO:0055123 289 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
lipid storage GO:0019915 1 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
nuclear transport GO:0051169 4 0.023
protein localization to nucleus GO:0034504 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
vasculature development GO:0001944 278 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
regulation of reproductive process GO:2000241 4 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
determination of left right symmetry GO:0007368 179 0.022
regulation of signaling GO:0023051 235 0.022
eye morphogenesis GO:0048592 144 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
cell part morphogenesis GO:0032990 246 0.022
developmental growth GO:0048589 166 0.021
hemopoiesis GO:0030097 183 0.021
muscle cell differentiation GO:0042692 139 0.021
regulation of developmental process GO:0050793 247 0.021
system process GO:0003008 185 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
blood vessel morphogenesis GO:0048514 216 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
rna metabolic process GO:0016070 219 0.021
cellular ketone metabolic process GO:0042180 11 0.021
gtp catabolic process GO:0006184 2 0.020
exocytosis GO:0006887 1 0.020
compound eye development GO:0048749 2 0.020
organic acid metabolic process GO:0006082 31 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of cell communication GO:0010646 232 0.020
blood vessel development GO:0001568 246 0.020
homeostatic process GO:0042592 142 0.020
oxoacid metabolic process GO:0043436 31 0.020
stem cell development GO:0048864 82 0.020
positive regulation of immune effector process GO:0002699 3 0.020
regulation of dendrite morphogenesis GO:0048814 3 0.020
peptidyl serine modification GO:0018209 2 0.020
positive regulation of secretion GO:0051047 1 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
meiotic nuclear division GO:0007126 4 0.019
heart development GO:0007507 313 0.019
cell substrate adhesion GO:0031589 4 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
response to carbohydrate GO:0009743 3 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
production of molecular mediator of immune response GO:0002440 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
regulation of protein catabolic process GO:0042176 1 0.018
pancreas development GO:0031016 84 0.018
golgi vesicle transport GO:0048193 3 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
spinal cord development GO:0021510 46 0.018
phagocytosis GO:0006909 3 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of binding GO:0051098 3 0.018
positive regulation of cell activation GO:0050867 1 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
neurotransmitter transport GO:0006836 2 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
spermatid differentiation GO:0048515 2 0.017
stem cell proliferation GO:0072089 4 0.017
female gonad development GO:0008585 4 0.017
protein import GO:0017038 3 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
single organism organelle organization GO:1902589 199 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
digestive tract development GO:0048565 265 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
response to external stimulus GO:0009605 264 0.017
neuron projection guidance GO:0097485 86 0.017
cellular component biogenesis GO:0044085 178 0.017
localization of cell GO:0051674 244 0.017
mononuclear cell proliferation GO:0032943 1 0.017
stem cell differentiation GO:0048863 117 0.017
regulation of dendrite development GO:0050773 3 0.017
mesenchyme development GO:0060485 127 0.017
developmental growth involved in morphogenesis GO:0060560 86 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
central nervous system neuron differentiation GO:0021953 74 0.016
protein acetylation GO:0006473 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
response to monosaccharide GO:0034284 3 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
protein metabolic process GO:0019538 183 0.016
embryonic heart tube development GO:0035050 133 0.016
protein localization to plasma membrane GO:0072659 1 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
response to stress GO:0006950 263 0.016
segmentation GO:0035282 97 0.016
germ line stem cell maintenance GO:0030718 2 0.016
chemosensory behavior GO:0007635 1 0.016
striated muscle cell differentiation GO:0051146 129 0.016
axon development GO:0061564 166 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of protein transport GO:0051223 3 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
response to drug GO:0042493 3 0.016
striated muscle tissue development GO:0014706 110 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
regulation of endocrine process GO:0044060 2 0.016
female sex differentiation GO:0046660 4 0.016
regulation of cell differentiation GO:0045595 142 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
single organism transport GO:0044765 206 0.016
detection of chemical stimulus GO:0009593 4 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
spermatid development GO:0007286 2 0.015
response to hexose GO:0009746 3 0.015
camera type eye development GO:0043010 222 0.015
growth GO:0040007 174 0.015
nuclear import GO:0051170 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
negative regulation of biological process GO:0048519 304 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
heart morphogenesis GO:0003007 156 0.015
protein import into nucleus GO:0006606 3 0.015
leukocyte proliferation GO:0070661 1 0.015
neurological system process GO:0050877 62 0.015
mesenchymal cell development GO:0014031 78 0.015
establishment of localization GO:0051234 244 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
cellular amide metabolic process GO:0043603 4 0.015
positive regulation of cell cycle GO:0045787 3 0.015
gastrulation GO:0007369 208 0.015
retina development in camera type eye GO:0060041 146 0.015
neuron projection morphogenesis GO:0048812 161 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
membrane fusion GO:0061025 2 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
transport GO:0006810 220 0.014
cytokinesis GO:0000910 3 0.014
embryonic heart tube morphogenesis GO:0003143 108 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
gtp metabolic process GO:0046039 4 0.014
lymphocyte proliferation GO:0046651 1 0.014
dicarboxylic acid transport GO:0006835 1 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
endocrine process GO:0050886 2 0.014
interspecies interaction between organisms GO:0044419 4 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
protein acylation GO:0043543 3 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
atp catabolic process GO:0006200 4 0.014
ameboidal type cell migration GO:0001667 143 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
hormone transport GO:0009914 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
immune system development GO:0002520 191 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
single organism metabolic process GO:0044710 217 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of reproductive process GO:2000243 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
water homeostasis GO:0030104 4 0.014
secondary metabolic process GO:0019748 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
meiotic cell cycle process GO:1903046 3 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
cell migration GO:0016477 237 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
small molecule metabolic process GO:0044281 77 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
organelle assembly GO:0070925 110 0.013
ear development GO:0043583 127 0.013
somatic muscle development GO:0007525 4 0.013
wnt signaling pathway GO:0016055 80 0.013
axonogenesis GO:0007409 152 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of synapse organization GO:0050807 3 0.013
muscle cell development GO:0055001 115 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of localization GO:0032879 104 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of neurogenesis GO:0050767 87 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
cellular protein metabolic process GO:0044267 129 0.012
glial cell migration GO:0008347 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
neural crest cell development GO:0014032 62 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of protein complex assembly GO:0043254 3 0.012
neural crest cell differentiation GO:0014033 72 0.012
neuron projection development GO:0031175 180 0.012
action potential GO:0001508 19 0.012
convergent extension GO:0060026 118 0.012
neuroblast proliferation GO:0007405 2 0.012
skeletal system development GO:0001501 181 0.012
lipid catabolic process GO:0016042 4 0.012
locomotor rhythm GO:0045475 3 0.012
cellular response to external stimulus GO:0071496 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
synaptic vesicle transport GO:0048489 1 0.012
b cell activation GO:0042113 2 0.012
adherens junction organization GO:0034332 4 0.012
single organism membrane fusion GO:0044801 2 0.012
carbohydrate homeostasis GO:0033500 1 0.012
hormone secretion GO:0046879 2 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
regulation of signal transduction GO:0009966 225 0.012
positive regulation of gene expression GO:0010628 71 0.012
regulation of nervous system development GO:0051960 90 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
peptide transport GO:0015833 1 0.012
lamellipodium organization GO:0097581 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
notochord development GO:0030903 54 0.012
epithelial cell differentiation GO:0030855 116 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
rna localization GO:0006403 4 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
amino acid transport GO:0006865 2 0.012
macromolecule modification GO:0043412 111 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
actin filament polymerization GO:0030041 2 0.011
cartilage development GO:0051216 96 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cell fate commitment GO:0045165 99 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
antimicrobial humoral response GO:0019730 2 0.011
post embryonic organ development GO:0048569 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
endocrine hormone secretion GO:0060986 2 0.011
digestive tract morphogenesis GO:0048546 231 0.011
regulation of mrna processing GO:0050684 3 0.011
cell death GO:0008219 121 0.011
gland development GO:0048732 143 0.011
regulation of lipid transport GO:0032368 4 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cell projection assembly GO:0030031 64 0.011
protein polymerization GO:0051258 4 0.011
negative regulation of signaling GO:0023057 96 0.011
camera type eye morphogenesis GO:0048593 108 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
regulation of dna replication GO:0006275 3 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
angiogenesis GO:0001525 158 0.011
somite development GO:0061053 96 0.011
cell matrix adhesion GO:0007160 4 0.011
neuronal action potential GO:0019228 18 0.011
sensory perception of pain GO:0019233 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cell fate specification GO:0001708 68 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
transmission of nerve impulse GO:0019226 19 0.011
intracellular signal transduction GO:0035556 85 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
glial cell proliferation GO:0014009 4 0.011
response to uv GO:0009411 3 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of stem cell proliferation GO:0072091 2 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
directional locomotion GO:0033058 1 0.010
positive regulation of multi organism process GO:0043902 3 0.010
response to wounding GO:0009611 116 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
otolith development GO:0048840 32 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
translational initiation GO:0006413 3 0.010
multi organism cellular process GO:0044764 2 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
cellular respiration GO:0045333 3 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
protein heterooligomerization GO:0051291 1 0.010
fertilization GO:0009566 3 0.010

brn1.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
disease of metabolism DOID:0014667 0 0.017
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
cardiovascular system disease DOID:1287 0 0.011
inherited metabolic disorder DOID:655 0 0.011