Danio rerio

0 known processes

idh1

isocitrate dehydrogenase 1 (NADP+), soluble

(Aliases: cb876,wu:fm90e09,im:7143416,MGC174090,MGC171441,fm90e09,MGC55806)

idh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component morphogenesis GO:0032989 336 0.450
small molecule metabolic process GO:0044281 77 0.402
Human Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.377
Human Mouse Fly
lipid catabolic process GO:0016042 4 0.368
response to xenobiotic stimulus GO:0009410 45 0.361
cellular response to xenobiotic stimulus GO:0071466 35 0.359
response to stress GO:0006950 263 0.358
Mouse
neuron development GO:0048666 262 0.347
gland development GO:0048732 143 0.337
organic acid metabolic process GO:0006082 31 0.334
Human Mouse Fly
locomotion GO:0040011 313 0.324
hemopoiesis GO:0030097 183 0.247
generation of neurons GO:0048699 385 0.241
cellular lipid catabolic process GO:0044242 3 0.235
lipid oxidation GO:0034440 1 0.224
single organism metabolic process GO:0044710 217 0.222
Human Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.217
neuron differentiation GO:0030182 353 0.215
cell part morphogenesis GO:0032990 246 0.212
oxidation reduction process GO:0055114 41 0.207
Human Mouse Fly
cell projection morphogenesis GO:0048858 244 0.185
lipid storage GO:0019915 1 0.181
eye development GO:0001654 277 0.181
regulation of biological quality GO:0065008 263 0.179
neuron projection development GO:0031175 180 0.176
amine metabolic process GO:0009308 2 0.174
negative regulation of cellular process GO:0048523 283 0.172
maintenance of location GO:0051235 4 0.153
aging GO:0007568 2 0.149
Worm
oxoacid metabolic process GO:0043436 31 0.138
Human Mouse Fly
central nervous system development GO:0007417 387 0.138
erk1 and erk2 cascade GO:0070371 4 0.132
axon development GO:0061564 166 0.127
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.127
response to oxidative stress GO:0006979 11 0.125
Mouse
response to hormone GO:0009725 48 0.120
response to external stimulus GO:0009605 264 0.120
negative regulation of biological process GO:0048519 304 0.116
positive regulation of transport GO:0051050 2 0.115
programmed cell death GO:0012501 119 0.110
cell morphogenesis GO:0000902 289 0.109
hepaticobiliary system development GO:0061008 98 0.108
small molecule catabolic process GO:0044282 3 0.105
response to endogenous stimulus GO:0009719 83 0.105
axon guidance GO:0007411 86 0.100
response to chemical GO:0042221 320 0.095
cell projection organization GO:0030030 284 0.088
organic substance biosynthetic process GO:1901576 289 0.087
fatty acid oxidation GO:0019395 1 0.081
cell morphogenesis involved in differentiation GO:0000904 195 0.081
regulation of metal ion transport GO:0010959 4 0.079
liver development GO:0001889 96 0.079
oxidoreduction coenzyme metabolic process GO:0006733 1 0.073
cellular response to extracellular stimulus GO:0031668 2 0.072
chemotaxis GO:0006935 104 0.072
single organism localization GO:1902578 225 0.071
response to drug GO:0042493 3 0.070
heterocycle metabolic process GO:0046483 290 0.068
erythrocyte differentiation GO:0030218 54 0.065
nuclear import GO:0051170 3 0.065
axonogenesis GO:0007409 152 0.063
cellular amine metabolic process GO:0044106 2 0.063
alcohol biosynthetic process GO:0046165 2 0.062
biosynthetic process GO:0009058 294 0.062
immune system development GO:0002520 191 0.060
regulation of programmed cell death GO:0043067 101 0.059
xenobiotic metabolic process GO:0006805 4 0.059
negative regulation of cytokine production GO:0001818 1 0.059
cellular response to chemical stimulus GO:0070887 157 0.058
cellular component movement GO:0006928 335 0.058
protein targeting to nucleus GO:0044744 3 0.057
cellular amino acid biosynthetic process GO:0008652 2 0.055
hydrogen peroxide metabolic process GO:0042743 2 0.055
response to lipid GO:0033993 60 0.055
cellular lipid metabolic process GO:0044255 36 0.054
single organism transport GO:0044765 206 0.052
regulation of cytokine production GO:0001817 3 0.051
neuron projection morphogenesis GO:0048812 161 0.050
signal transduction GO:0007165 455 0.050
regulation of reproductive process GO:2000241 4 0.050
fatty acid catabolic process GO:0009062 1 0.049
negative regulation of metabolic process GO:0009892 86 0.048
neuron projection guidance GO:0097485 86 0.047
regulation of cellular amine metabolic process GO:0033238 0 0.047
cellular biosynthetic process GO:0044249 286 0.047
determination of left right symmetry GO:0007368 179 0.047
organelle organization GO:0006996 227 0.046
cell motility GO:0048870 244 0.046
cellular macromolecule metabolic process GO:0044260 391 0.046
death GO:0016265 121 0.045
larval development GO:0002164 2 0.045
establishment of localization in cell GO:0051649 77 0.043
cellular ketone metabolic process GO:0042180 11 0.042
camera type eye development GO:0043010 222 0.042
cellular amino acid metabolic process GO:0006520 7 0.042
Mouse
macromolecule biosynthetic process GO:0009059 227 0.041
cellular response to external stimulus GO:0071496 2 0.041
cytoplasm organization GO:0007028 4 0.041
regulation of cell communication GO:0010646 232 0.041
ion homeostasis GO:0050801 41 0.041
adult behavior GO:0030534 2 0.039
response to organic substance GO:0010033 153 0.039
response to hydrogen peroxide GO:0042542 3 0.039
cation homeostasis GO:0055080 33 0.038
organonitrogen compound metabolic process GO:1901564 74 0.037
Mouse
heart morphogenesis GO:0003007 156 0.037
regulation of cytoplasmic transport GO:1903649 4 0.036
regulation of signal transduction GO:0009966 225 0.036
cell migration GO:0016477 237 0.036
taxis GO:0042330 109 0.036
tyrosine phosphorylation of stat protein GO:0007260 1 0.036
fatty acid beta oxidation GO:0006635 1 0.035
nucleocytoplasmic transport GO:0006913 4 0.035
regulation of ion transmembrane transporter activity GO:0032412 2 0.035
regulation of erk1 and erk2 cascade GO:0070372 4 0.035
homeostatic process GO:0042592 142 0.034
cellular component biogenesis GO:0044085 178 0.034
glucose homeostasis GO:0042593 1 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
protein localization to nucleus GO:0034504 3 0.033
establishment of localization GO:0051234 244 0.033
pancreas development GO:0031016 84 0.033
response to biotic stimulus GO:0009607 97 0.033
protein localization to plasma membrane GO:0072659 1 0.032
specification of symmetry GO:0009799 204 0.032
cellular response to nutrient levels GO:0031669 2 0.032
determination of bilateral symmetry GO:0009855 204 0.032
erythrocyte homeostasis GO:0034101 55 0.032
homeostasis of number of cells GO:0048872 62 0.032
regulation of apoptotic process GO:0042981 98 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
metal ion homeostasis GO:0055065 26 0.031
embryonic organ development GO:0048568 381 0.030
carboxylic acid catabolic process GO:0046395 3 0.030
monocarboxylic acid catabolic process GO:0072329 3 0.030
phosphorus metabolic process GO:0006793 109 0.030
brain development GO:0007420 293 0.030
cellular response to topologically incorrect protein GO:0035967 2 0.029
lipid metabolic process GO:0006629 52 0.029
cellular macromolecular complex assembly GO:0034622 24 0.029
apoptotic process GO:0006915 116 0.029
regulation of cell migration GO:0030334 40 0.029
negative regulation of mapk cascade GO:0043409 4 0.029
organic hydroxy compound biosynthetic process GO:1901617 6 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Mouse
regulation of locomotion GO:0040012 55 0.027
protein polymerization GO:0051258 4 0.027
multi organism process GO:0051704 134 0.027
cell death GO:0008219 121 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
regulation of protein import into nucleus GO:0042306 2 0.026
response to uv GO:0009411 3 0.026
regulation of localization GO:0032879 104 0.026
cellular pigmentation GO:0033059 30 0.025
regulation of metabolic process GO:0019222 359 0.025
chemical homeostasis GO:0048878 49 0.025
actin polymerization or depolymerization GO:0008154 2 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
negative regulation of apoptotic process GO:0043066 55 0.025
multicellular organismal response to stress GO:0033555 2 0.025
nucleoside biosynthetic process GO:0009163 2 0.025
negative regulation of reproductive process GO:2000242 3 0.024
heart development GO:0007507 313 0.024
response to nutrient GO:0007584 3 0.024
regulation of cell death GO:0010941 103 0.024
actin filament polymerization GO:0030041 2 0.024
protein import into nucleus GO:0006606 3 0.024
negative regulation of cell death GO:0060548 60 0.023
rna localization GO:0006403 4 0.023
multicellular organism growth GO:0035264 4 0.023
negative regulation of signal transduction GO:0009968 94 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
negative regulation of cell communication GO:0010648 96 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
myeloid cell differentiation GO:0030099 86 0.022
transport GO:0006810 220 0.022
neurotransmitter transport GO:0006836 2 0.022
actin cytoskeleton organization GO:0030036 63 0.022
cellular amide metabolic process GO:0043603 4 0.022
Mouse
response to copper ion GO:0046688 13 0.022
response to inorganic substance GO:0010035 38 0.022
phagocytosis GO:0006909 3 0.022
regulation of calcium ion transport GO:0051924 2 0.022
peptide metabolic process GO:0006518 1 0.022
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.021
regulation of signaling GO:0023051 235 0.021
transcription dna templated GO:0006351 181 0.021
macromolecular complex assembly GO:0065003 35 0.021
sensory organ development GO:0007423 393 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
response to starvation GO:0042594 5 0.020
regulation of neuronal synaptic plasticity GO:0048168 1 0.020
immune system process GO:0002376 241 0.020
interaction with host GO:0051701 4 0.020
alcohol metabolic process GO:0006066 11 0.020
exocytosis GO:0006887 1 0.020
regulation of jak stat cascade GO:0046425 3 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
macromolecular complex subunit organization GO:0043933 74 0.019
regulation of cell motility GO:2000145 46 0.019
negative regulation of intracellular signal transduction GO:1902532 22 0.019
monocarboxylic acid metabolic process GO:0032787 17 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
organic acid catabolic process GO:0016054 3 0.019
response to topologically incorrect protein GO:0035966 2 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
nuclear transport GO:0051169 4 0.019
response to external biotic stimulus GO:0043207 97 0.019
eye morphogenesis GO:0048592 144 0.019
dicarboxylic acid metabolic process GO:0043648 1 0.019
Human
localization of cell GO:0051674 244 0.019
cellular response to organic substance GO:0071310 105 0.019
cellular localization GO:0051641 97 0.019
positive regulation of cell cycle GO:0045787 3 0.018
single organism biosynthetic process GO:0044711 71 0.018
respiratory electron transport chain GO:0022904 2 0.018
regulation of protein complex assembly GO:0043254 3 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
hormone metabolic process GO:0042445 19 0.018
response to other organism GO:0051707 97 0.017
regulation of transporter activity GO:0032409 2 0.017
autophagy GO:0006914 4 0.017
myeloid cell homeostasis GO:0002262 56 0.017
cellular response to reactive oxygen species GO:0034614 2 0.017
regulation of cytokine mediated signaling pathway GO:0001959 3 0.017
response to fatty acid GO:0070542 5 0.017
ovulation cycle GO:0042698 2 0.017
response to alkaloid GO:0043279 2 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.016
lipid localization GO:0010876 11 0.016
pole plasm assembly GO:0007315 4 0.016
endosomal transport GO:0016197 2 0.016
inositol lipid mediated signaling GO:0048017 2 0.016
tube morphogenesis GO:0035239 349 0.016
regulation of cellular component movement GO:0051270 55 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
embryonic hemopoiesis GO:0035162 53 0.016
response to extracellular stimulus GO:0009991 10 0.016
regulation of protein polymerization GO:0032271 2 0.016
negative regulation of endopeptidase activity GO:0010951 10 0.016
cellular response to fatty acid GO:0071398 3 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
viral process GO:0016032 1 0.016
pyruvate metabolic process GO:0006090 1 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
protein metabolic process GO:0019538 183 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
transmembrane transport GO:0055085 120 0.015
single organism carbohydrate metabolic process GO:0044723 12 0.015
organophosphate metabolic process GO:0019637 37 0.015
organophosphate biosynthetic process GO:0090407 23 0.015
cellular component assembly GO:0022607 170 0.015
regulation of protein transport GO:0051223 3 0.015
protein import GO:0017038 3 0.015
regulation of synapse organization GO:0050807 3 0.015
nitrogen compound metabolic process GO:0006807 319 0.015
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
single organism nuclear import GO:1902593 3 0.015
collagen metabolic process GO:0032963 2 0.014
divalent inorganic cation homeostasis GO:0072507 22 0.014
response to oxygen containing compound GO:1901700 55 0.014
regulation of lipid catabolic process GO:0050994 2 0.014
response to corticosteroid GO:0031960 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
cytokinesis GO:0000910 3 0.014
cellular hormone metabolic process GO:0034754 19 0.014
central nervous system neuron axonogenesis GO:0021955 18 0.014
electron transport chain GO:0022900 2 0.014
inorganic ion transmembrane transport GO:0098660 57 0.014
single organism cellular localization GO:1902580 46 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
protein complex biogenesis GO:0070271 30 0.014
sensory organ morphogenesis GO:0090596 200 0.013
response to steroid hormone GO:0048545 35 0.013
mitochondrial transport GO:0006839 2 0.013
negative regulation of signaling GO:0023057 96 0.013
rna metabolic process GO:0016070 219 0.013
regulation of membrane potential GO:0042391 23 0.013
developmental maturation GO:0021700 34 0.013
response to nitrogen compound GO:1901698 19 0.013
fatty acid metabolic process GO:0006631 5 0.013
cellular response to methanol GO:0071405 4 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
ph reduction GO:0045851 1 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
regulation of transcription dna templated GO:0006355 213 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
ion transport GO:0006811 114 0.013
organic hydroxy compound transport GO:0015850 14 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
response to bacterium GO:0009617 58 0.013
carbohydrate metabolic process GO:0005975 12 0.013
response to ketone GO:1901654 1 0.013
calcium ion dependent exocytosis GO:0017156 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
superoxide metabolic process GO:0006801 2 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of cell activation GO:0050865 1 0.012
cellular response to unfolded protein GO:0034620 2 0.012
response to light stimulus GO:0009416 46 0.012
negative regulation of protein transport GO:0051224 3 0.012
energy reserve metabolic process GO:0006112 2 0.012
multi organism cellular process GO:0044764 2 0.012
single organism intracellular transport GO:1902582 25 0.012
digestive tract morphogenesis GO:0048546 231 0.012
negative regulation of locomotion GO:0040013 18 0.012
secondary metabolic process GO:0019748 3 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
cellular respiration GO:0045333 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
gene expression GO:0010467 252 0.012
organic hydroxy compound metabolic process GO:1901615 16 0.012
macromolecule localization GO:0033036 54 0.012
small molecule biosynthetic process GO:0044283 16 0.011
protein phosphorylation GO:0006468 47 0.011
carbohydrate homeostasis GO:0033500 1 0.011
defense response GO:0006952 47 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
response to food GO:0032094 1 0.011
regulation of gene expression GO:0010468 265 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
regulation of jun kinase activity GO:0043506 3 0.011
peptidyl serine modification GO:0018209 2 0.011
cellular response to starvation GO:0009267 1 0.011
developmental growth GO:0048589 166 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
collagen biosynthetic process GO:0032964 2 0.011
retina development in camera type eye GO:0060041 146 0.011
negative regulation of jnk cascade GO:0046329 1 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
cellular protein catabolic process GO:0044257 4 0.011
positive regulation of biological process GO:0048518 253 0.011
protein complex assembly GO:0006461 30 0.011
intrinsic apoptotic signaling pathway GO:0097193 20 0.011
meiotic cell cycle process GO:1903046 3 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010
endoplasmic reticulum unfolded protein response GO:0030968 2 0.010
cellular response to stress GO:0033554 62 0.010
wound healing GO:0042060 90 0.010
hormone biosynthetic process GO:0042446 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
organic acid biosynthetic process GO:0016053 12 0.010
regulation of response to stimulus GO:0048583 269 0.010
interspecies interaction between organisms GO:0044419 4 0.010
ovulation cycle process GO:0022602 2 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010

idh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
disease of metabolism DOID:0014667 0 0.039
inherited metabolic disorder DOID:655 0 0.039
nervous system disease DOID:863 0 0.023