Danio rerio

0 known processes

gnsb

glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b

(Aliases: gns,wu:fi20h10,zgc:55370)

gnsb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 271 0.227
Zebrafish
larval development GO:0002164 2 0.131
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.119
cellular nitrogen compound metabolic process GO:0034641 290 0.102
nucleobase containing compound metabolic process GO:0006139 274 0.101
nitrogen compound metabolic process GO:0006807 319 0.095
single organism metabolic process GO:0044710 217 0.095
chordate embryonic development GO:0043009 271 0.094
Zebrafish
lipid storage GO:0019915 1 0.094
microtubule organizing center organization GO:0031023 1 0.089
ameboidal type cell migration GO:0001667 143 0.083
transport GO:0006810 220 0.079
maintenance of location GO:0051235 4 0.077
hemopoiesis GO:0030097 183 0.075
phagocytosis GO:0006909 3 0.061
system process GO:0003008 185 0.059
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.058
regulation of biological quality GO:0065008 263 0.058
cellular aromatic compound metabolic process GO:0006725 295 0.056
meiotic nuclear division GO:0007126 4 0.055
organic cyclic compound biosynthetic process GO:1901362 223 0.055
regulation of response to stimulus GO:0048583 269 0.054
regulation of cellular amine metabolic process GO:0033238 0 0.054
positive regulation of transport GO:0051050 2 0.054
regulation of rna metabolic process GO:0051252 224 0.053
homeostatic process GO:0042592 142 0.052
cellular amine metabolic process GO:0044106 2 0.052
heterocycle biosynthetic process GO:0018130 215 0.052
stem cell maintenance GO:0019827 4 0.051
hematopoietic or lymphoid organ development GO:0048534 191 0.051
cognition GO:0050890 1 0.051
organic cyclic compound metabolic process GO:1901360 301 0.051
brain development GO:0007420 293 0.050
guanosine containing compound metabolic process GO:1901068 4 0.050
organelle organization GO:0006996 227 0.049
regulation of cellular metabolic process GO:0031323 320 0.049
response to stress GO:0006950 263 0.048
morphogenesis of an epithelium GO:0002009 333 0.047
cellular ketone metabolic process GO:0042180 11 0.047
regulation of metabolic process GO:0019222 359 0.047
regulation of cell communication GO:0010646 232 0.046
aging GO:0007568 2 0.046
regulation of cellular ketone metabolic process GO:0010565 7 0.045
regulation of signaling GO:0023051 235 0.045
regulation of synapse organization GO:0050807 3 0.045
small molecule metabolic process GO:0044281 77 0.045
epithelial cell differentiation GO:0030855 116 0.045
stem cell development GO:0048864 82 0.043
positive regulation of secretion by cell GO:1903532 1 0.043
response to external stimulus GO:0009605 264 0.042
cell motility GO:0048870 244 0.042
Zebrafish
amine metabolic process GO:0009308 2 0.041
carboxylic acid metabolic process GO:0019752 22 0.041
establishment of localization GO:0051234 244 0.041
negative regulation of cellular process GO:0048523 283 0.040
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.040
positive regulation of muscle cell differentiation GO:0051149 1 0.039
immune system process GO:0002376 241 0.039
regulation of biosynthetic process GO:0009889 250 0.038
lipid homeostasis GO:0055088 3 0.037
aromatic compound biosynthetic process GO:0019438 217 0.037
stem cell proliferation GO:0072089 4 0.037
neuron neuron synaptic transmission GO:0007270 1 0.037
cellular response to extracellular stimulus GO:0031668 2 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
glucose homeostasis GO:0042593 1 0.037
single organism transport GO:0044765 206 0.037
modification dependent protein catabolic process GO:0019941 3 0.037
cellular protein catabolic process GO:0044257 4 0.037
central nervous system development GO:0007417 387 0.036
Zebrafish
phagocytosis engulfment GO:0006911 1 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
centrosome organization GO:0051297 1 0.036
carbohydrate homeostasis GO:0033500 1 0.035
tube closure GO:0060606 1 0.035
regulation of stem cell differentiation GO:2000736 4 0.034
cellular response to external stimulus GO:0071496 2 0.034
response to chemical GO:0042221 320 0.033
signal transduction GO:0007165 455 0.033
Zebrafish
cellular lipid metabolic process GO:0044255 36 0.033
stem cell differentiation GO:0048863 117 0.033
response to lipid GO:0033993 60 0.033
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.032
regulation of metal ion transport GO:0010959 4 0.032
immune system development GO:0002520 191 0.032
organic acid metabolic process GO:0006082 31 0.031
positive regulation of biological process GO:0048518 253 0.031
heart development GO:0007507 313 0.031
tissue remodeling GO:0048771 4 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
oxoacid metabolic process GO:0043436 31 0.031
single organism localization GO:1902578 225 0.031
rna biosynthetic process GO:0032774 181 0.031
localization of cell GO:0051674 244 0.030
Zebrafish
muscle structure development GO:0061061 196 0.030
muscle organ development GO:0007517 101 0.030
alpha amino acid metabolic process GO:1901605 3 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
peptide transport GO:0015833 1 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
negative regulation of chromosome organization GO:2001251 1 0.030
cell migration GO:0016477 237 0.030
Zebrafish
female meiotic division GO:0007143 2 0.029
positive regulation of cell killing GO:0031343 2 0.029
cell matrix adhesion GO:0007160 4 0.029
regulation of cell activation GO:0050865 1 0.029
regulation of cytokine production GO:0001817 3 0.029
biosynthetic process GO:0009058 294 0.029
guanosine containing compound catabolic process GO:1901069 2 0.028
tube morphogenesis GO:0035239 349 0.028
membrane invagination GO:0010324 1 0.028
regulation of localization GO:0032879 104 0.028
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.028
cellular response to oxygen levels GO:0071453 1 0.028
monoamine transport GO:0015844 1 0.027
b cell differentiation GO:0030183 1 0.027
cellular component movement GO:0006928 335 0.027
Zebrafish
positive regulation of jnk cascade GO:0046330 3 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
angiogenesis GO:0001525 158 0.027
response to drug GO:0042493 3 0.027
peptidyl lysine acetylation GO:0018394 2 0.027
positive regulation of protein complex assembly GO:0031334 2 0.026
response to corticosteroid GO:0031960 1 0.025
neurotransmitter transport GO:0006836 2 0.025
organic substance biosynthetic process GO:1901576 289 0.025
response to hexose GO:0009746 3 0.025
skeletal muscle organ development GO:0060538 78 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
cellular response to hypoxia GO:0071456 1 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
Zebrafish
double strand break repair GO:0006302 3 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.024
gtp catabolic process GO:0006184 2 0.023
negative regulation of chromatin modification GO:1903309 1 0.023
regulation of binding GO:0051098 3 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
gtp metabolic process GO:0046039 4 0.023
transmembrane transport GO:0055085 120 0.023
protein acetylation GO:0006473 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
positive regulation of map kinase activity GO:0043406 3 0.022
multi organism process GO:0051704 134 0.022
synaptic vesicle recycling GO:0036465 1 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
sensory system development GO:0048880 76 0.022
Zebrafish
negative regulation of dna metabolic process GO:0051053 4 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
regulation of calcium ion transport GO:0051924 2 0.022
regulation of transcription dna templated GO:0006355 213 0.022
nuclear transport GO:0051169 4 0.022
cellular response to starvation GO:0009267 1 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.021
somatic stem cell maintenance GO:0035019 1 0.021
positive regulation of secretion GO:0051047 1 0.021
positive regulation of cytokine production GO:0001819 2 0.021
positive regulation of cell cycle GO:0045787 3 0.021
cellular modified amino acid metabolic process GO:0006575 3 0.021
nucleic acid metabolic process GO:0090304 244 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
regulation of cell shape GO:0008360 1 0.021
establishment of synaptic vesicle localization GO:0097480 1 0.021
positive regulation of cell activation GO:0050867 1 0.020
somitogenesis GO:0001756 87 0.020
Zebrafish
cellular biosynthetic process GO:0044249 286 0.020
antimicrobial humoral response GO:0019730 2 0.020
lipid catabolic process GO:0016042 4 0.020
protein polyubiquitination GO:0000209 4 0.020
response to monosaccharide GO:0034284 3 0.020
hindbrain development GO:0030902 91 0.020
response to hormone GO:0009725 48 0.020
post embryonic organ development GO:0048569 4 0.020
cellular response to decreased oxygen levels GO:0036294 1 0.020
positive regulation of leukocyte differentiation GO:1902107 1 0.020
single organism organelle organization GO:1902589 199 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
cell cycle arrest GO:0007050 1 0.020
regulation of cell killing GO:0031341 2 0.020
positive regulation of immune effector process GO:0002699 3 0.020
fatty acid biosynthetic process GO:0006633 4 0.019
protein acylation GO:0043543 3 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
positive regulation of stress activated mapk cascade GO:0032874 3 0.019
regulation of cell substrate adhesion GO:0010810 1 0.019
hormone transport GO:0009914 2 0.019
digestive system development GO:0055123 289 0.019
adult behavior GO:0030534 2 0.019
establishment or maintenance of cell polarity GO:0007163 29 0.018
regulation of cellular component organization GO:0051128 86 0.018
head development GO:0060322 303 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
blood vessel development GO:0001568 246 0.018
Zebrafish
regulation of gtpase activity GO:0043087 2 0.018
regulation of blood pressure GO:0008217 1 0.018
regulation of cell migration GO:0030334 40 0.018
Zebrafish
negative regulation of developmental process GO:0051093 65 0.018
single organism biosynthetic process GO:0044711 71 0.018
locomotion GO:0040011 313 0.018
Zebrafish
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
negative regulation of myeloid cell differentiation GO:0045638 1 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
homeostasis of number of cells GO:0048872 62 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
spindle assembly GO:0051225 2 0.018
protein import GO:0017038 3 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
response to organic cyclic compound GO:0014070 51 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
response to glucose GO:0009749 3 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
synaptic vesicle transport GO:0048489 1 0.017
neural crest cell differentiation GO:0014033 72 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
cellular lipid catabolic process GO:0044242 3 0.017
neuroblast proliferation GO:0007405 2 0.017
cell substrate junction assembly GO:0007044 2 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
heterocycle metabolic process GO:0046483 290 0.017
blood circulation GO:0008015 87 0.017
Zebrafish
regulation of synapse assembly GO:0051963 3 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.016
spermatid differentiation GO:0048515 2 0.016
posterior lateral line system development GO:0048915 46 0.016
regulation of synaptic vesicle transport GO:1902803 1 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
response to external biotic stimulus GO:0043207 97 0.016
positive regulation of jun kinase activity GO:0043507 2 0.016
long chain fatty acid transport GO:0015909 1 0.016
nucleic acid templated transcription GO:0097659 181 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of response to stress GO:0080134 36 0.016
b cell activation GO:0042113 2 0.016
primary neural tube formation GO:0014020 1 0.016
transcription dna templated GO:0006351 181 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of endocytosis GO:0030100 7 0.016
regulation of fatty acid metabolic process GO:0019217 1 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
positive regulation of multi organism process GO:0043902 3 0.016
regulation of cell matrix adhesion GO:0001952 1 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
segmentation GO:0035282 97 0.016
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.016
peptidyl serine modification GO:0018209 2 0.015
cellular response to stress GO:0033554 62 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
Zebrafish
epithelial cell morphogenesis GO:0003382 2 0.015
mesenchyme development GO:0060485 127 0.015
meiotic cell cycle process GO:1903046 3 0.015
regulation of hormone secretion GO:0046883 2 0.015
behavior GO:0007610 74 0.015
endosomal transport GO:0016197 2 0.015
regulation of protein transport GO:0051223 3 0.015
lateral line development GO:0048882 66 0.015
Zebrafish
hormone secretion GO:0046879 2 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
actin filament polymerization GO:0030041 2 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
mesenchymal cell development GO:0014031 78 0.015
lipid metabolic process GO:0006629 52 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
response to organic substance GO:0010033 153 0.014
regulation of organ growth GO:0046620 3 0.014
vacuolar transport GO:0007034 2 0.014
response to other organism GO:0051707 97 0.014
regulation of cell motility GO:2000145 46 0.014
Zebrafish
leukocyte homeostasis GO:0001776 2 0.014
fatty acid transport GO:0015908 1 0.014
female sex differentiation GO:0046660 4 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
regulation of developmental process GO:0050793 247 0.014
Zebrafish
regulation of molecular function GO:0065009 70 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
response to ketone GO:1901654 1 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
glycerolipid biosynthetic process GO:0045017 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of protein polymerization GO:0032271 2 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
synaptic vesicle localization GO:0097479 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
Zebrafish
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
blood vessel morphogenesis GO:0048514 216 0.013
Zebrafish
lipid localization GO:0010876 11 0.013
calcium ion import GO:0070509 4 0.013
regulation of locomotion GO:0040012 55 0.013
Zebrafish
positive regulation of lipid metabolic process GO:0045834 1 0.013
lateral inhibition GO:0046331 1 0.013
photoreceptor cell differentiation GO:0046530 55 0.013
protein targeting to nucleus GO:0044744 3 0.013
gene expression GO:0010467 252 0.013
positive regulation of catabolic process GO:0009896 4 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
nuclear import GO:0051170 3 0.013
protein metabolic process GO:0019538 183 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
regulation of primary metabolic process GO:0080090 311 0.013
regulation of immune system process GO:0002682 34 0.013
lipid oxidation GO:0034440 1 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
spermatid development GO:0007286 2 0.013
intracellular signal transduction GO:0035556 85 0.013
post embryonic morphogenesis GO:0009886 4 0.013
positive regulation of gliogenesis GO:0014015 2 0.013
protein homooligomerization GO:0051260 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
single organism nuclear import GO:1902593 3 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
ion transport GO:0006811 114 0.012
regulation of cell differentiation GO:0045595 142 0.012
exocytosis GO:0006887 1 0.012
organophosphate metabolic process GO:0019637 37 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
positive regulation of gene expression GO:0010628 71 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.012
neural crest cell development GO:0014032 62 0.012
negative chemotaxis GO:0050919 1 0.012
specification of organ identity GO:0010092 2 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
response to bacterium GO:0009617 58 0.012
single fertilization GO:0007338 3 0.012
sleep GO:0030431 1 0.012
positive regulation of cellular process GO:0048522 201 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of gene expression GO:0010468 265 0.012
camera type eye development GO:0043010 222 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
ras protein signal transduction GO:0007265 7 0.012
rna metabolic process GO:0016070 219 0.012
regulation of cellular component movement GO:0051270 55 0.012
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.012
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of jun kinase activity GO:0043506 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
leukocyte proliferation GO:0070661 1 0.011
female gonad development GO:0008585 4 0.011
response to wounding GO:0009611 116 0.011
endocytosis GO:0006897 16 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of inflammatory response GO:0050727 2 0.011
eye morphogenesis GO:0048592 144 0.011
lymphocyte proliferation GO:0046651 1 0.011
fertilization GO:0009566 3 0.011
cardiac cell fate commitment GO:0060911 1 0.011
response to alkaloid GO:0043279 2 0.011
regulation of autophagy GO:0010506 3 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
negative regulation of histone modification GO:0031057 1 0.011
collagen metabolic process GO:0032963 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
cellular response to lipid GO:0071396 39 0.011
bone remodeling GO:0046849 2 0.011
regulation of signal transduction GO:0009966 225 0.011
negative regulation of cell death GO:0060548 60 0.011
glucocorticoid metabolic process GO:0008211 2 0.011
cartilage condensation GO:0001502 3 0.011
megakaryocyte differentiation GO:0030219 1 0.011
fin development GO:0033333 77 0.011
protein localization to nucleus GO:0034504 3 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
ion transmembrane transport GO:0034220 91 0.011
lymph vessel morphogenesis GO:0036303 25 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cell killing GO:0001906 2 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
somatic muscle development GO:0007525 4 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
digestive system process GO:0022600 9 0.010
cell adhesion GO:0007155 40 0.010
regulation of growth rate GO:0040009 1 0.010
epidermis development GO:0008544 48 0.010
locomotor rhythm GO:0045475 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
pigment cell differentiation GO:0050931 38 0.010
positive regulation of cell communication GO:0010647 56 0.010
neurotransmitter secretion GO:0007269 2 0.010
protein import into nucleus GO:0006606 3 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
lamellipodium assembly GO:0030032 1 0.010
response to biotic stimulus GO:0009607 97 0.010
regulation of mrna processing GO:0050684 3 0.010
mesodermal cell migration GO:0008078 12 0.010
peptide metabolic process GO:0006518 1 0.010
dna templated transcription elongation GO:0006354 3 0.010
response to oxygen containing compound GO:1901700 55 0.010
positive regulation of metabolic process GO:0009893 108 0.010
macromolecular complex disassembly GO:0032984 1 0.010

gnsb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010