Danio rerio

24 known processes

yy1b

YY1 transcription factor b

(Aliases: zgc:64207,yy1l)

yy1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell proliferation GO:0072089 4 0.193
regulation of cellular metabolic process GO:0031323 320 0.172
Human Rat Fly
nitrogen compound metabolic process GO:0006807 319 0.138
Human Rat Fly
stem cell maintenance GO:0019827 4 0.126
cellular macromolecule metabolic process GO:0044260 391 0.118
Human Rat Fly
regulation of macromolecule metabolic process GO:0060255 317 0.113
Human Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.111
Human Rat Fly
gene expression GO:0010467 252 0.092
Human Rat Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.091
regulation of rna biosynthetic process GO:2001141 213 0.083
Human Rat Fly
negative regulation of cellular process GO:0048523 283 0.075
Human Rat Fly
cell migration GO:0016477 237 0.069
modification dependent macromolecule catabolic process GO:0043632 3 0.068
maintenance of location GO:0051235 4 0.067
multicellular organism growth GO:0035264 4 0.066
larval development GO:0002164 2 0.065
aging GO:0007568 2 0.064
ubiquitin dependent protein catabolic process GO:0006511 3 0.062
meiotic nuclear division GO:0007126 4 0.062
rna metabolic process GO:0016070 219 0.058
Human Rat Fly
protein polymerization GO:0051258 4 0.057
amine metabolic process GO:0009308 2 0.055
signal transduction GO:0007165 455 0.054
cellular protein catabolic process GO:0044257 4 0.053
regulation of multicellular organism growth GO:0040014 4 0.053
modification dependent protein catabolic process GO:0019941 3 0.053
protein polyubiquitination GO:0000209 4 0.053
response to drug GO:0042493 3 0.052
nucleocytoplasmic transport GO:0006913 4 0.052
cellular protein modification process GO:0006464 100 0.052
cellular biosynthetic process GO:0044249 286 0.051
Human Rat Fly
proteasomal protein catabolic process GO:0010498 2 0.051
regulation of metabolic process GO:0019222 359 0.048
regulation of meiotic cell cycle GO:0051445 1 0.047
regulation of primary metabolic process GO:0080090 311 0.046
positive regulation of biological process GO:0048518 253 0.045
Rat Fly
regulation of biosynthetic process GO:0009889 250 0.045
neuroblast proliferation GO:0007405 2 0.045
regulation of transcription dna templated GO:0006355 213 0.043
Human Rat Fly
cellular component assembly GO:0022607 170 0.042
positive regulation of transport GO:0051050 2 0.042
regulation of synapse assembly GO:0051963 3 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
positive regulation of cellular metabolic process GO:0031325 94 0.042
Rat Fly
protein localization to nucleus GO:0034504 3 0.041
single organism nuclear import GO:1902593 3 0.041
protein targeting to nucleus GO:0044744 3 0.041
cellular amine metabolic process GO:0044106 2 0.040
cellular component disassembly GO:0022411 1 0.038
protein k48 linked ubiquitination GO:0070936 1 0.038
nuclear transport GO:0051169 4 0.037
organelle organization GO:0006996 227 0.037
Fly
single organism organelle organization GO:1902589 199 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
cytokinesis GO:0000910 3 0.035
negative regulation of ras protein signal transduction GO:0046580 1 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.035
Human Rat Fly
negative regulation of biological process GO:0048519 304 0.035
Human Rat Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.035
chromatin modification GO:0016568 21 0.035
Fly
stem cell division GO:0017145 1 0.034
heterocycle metabolic process GO:0046483 290 0.034
Human Rat Fly
protein import GO:0017038 3 0.034
cell motility GO:0048870 244 0.034
microtubule polymerization or depolymerization GO:0031109 3 0.034
regulation of developmental process GO:0050793 247 0.034
cellular component biogenesis GO:0044085 178 0.033
rna 3 end processing GO:0031123 2 0.033
spindle assembly GO:0051225 2 0.033
protein metabolic process GO:0019538 183 0.033
regulation of synapse organization GO:0050807 3 0.032
macromolecule modification GO:0043412 111 0.032
regulation of cellular biosynthetic process GO:0031326 245 0.032
Human Rat Fly
chromosome organization GO:0051276 31 0.031
Fly
internal peptidyl lysine acetylation GO:0018393 2 0.031
cellular protein metabolic process GO:0044267 129 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
cellular component morphogenesis GO:0032989 336 0.031
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
Human Rat Fly
organic acid metabolic process GO:0006082 31 0.030
small molecule metabolic process GO:0044281 77 0.030
regulation of gene expression GO:0010468 265 0.030
Human Rat Fly
protein import into nucleus GO:0006606 3 0.030
meiotic chromosome segregation GO:0045132 3 0.029
lipid storage GO:0019915 1 0.029
meiotic cell cycle process GO:1903046 3 0.029
protein modification process GO:0036211 100 0.029
macromolecular complex subunit organization GO:0043933 74 0.029
Fly
centrosome organization GO:0051297 1 0.029
intracellular signal transduction GO:0035556 85 0.029
protein acetylation GO:0006473 2 0.029
positive regulation of catabolic process GO:0009896 4 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
Human Rat Fly
regulation of establishment of protein localization GO:0070201 4 0.029
organonitrogen compound metabolic process GO:1901564 74 0.028
enzyme linked receptor protein signaling pathway GO:0007167 106 0.028
positive regulation of metabolic process GO:0009893 108 0.027
Rat Fly
regulation of protein transport GO:0051223 3 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
Human Rat Fly
single organism metabolic process GO:0044710 217 0.027
locomotion GO:0040011 313 0.027
regulation of signal transduction GO:0009966 225 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of rna metabolic process GO:0051252 224 0.026
Human Rat Fly
regulation of response to stimulus GO:0048583 269 0.026
organelle assembly GO:0070925 110 0.026
cellular ketone metabolic process GO:0042180 11 0.025
regulation of cell shape GO:0008360 1 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
chromosome organization involved in meiosis GO:0070192 1 0.025
mononuclear cell proliferation GO:0032943 1 0.025
regulation of cell communication GO:0010646 232 0.025
biosynthetic process GO:0009058 294 0.025
centrosome cycle GO:0007098 1 0.025
regulation of cell activation GO:0050865 1 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
Human Rat Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
Human Rat Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.024
response to hexose GO:0009746 3 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
Human Rat
cellular aromatic compound metabolic process GO:0006725 295 0.024
Human Rat Fly
peptidyl lysine acetylation GO:0018394 2 0.024
carboxylic acid metabolic process GO:0019752 22 0.023
regulation of biological quality GO:0065008 263 0.023
cell part morphogenesis GO:0032990 246 0.023
Fly
protein complex disassembly GO:0043241 1 0.023
nuclear import GO:0051170 3 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
Human Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
Rat Fly
macromolecule biosynthetic process GO:0009059 227 0.023
Human Rat Fly
regulation of cytokine production GO:0001817 3 0.023
positive regulation of cell activation GO:0050867 1 0.023
regulation of signaling GO:0023051 235 0.023
peptidyl threonine phosphorylation GO:0018107 1 0.022
negative regulation of dna metabolic process GO:0051053 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
Human
apoptotic process GO:0006915 116 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
mitotic cell cycle GO:0000278 64 0.022
negative regulation of myeloid cell differentiation GO:0045638 1 0.022
oxoacid metabolic process GO:0043436 31 0.022
response to chemical GO:0042221 320 0.021
Rat
cellular component movement GO:0006928 335 0.021
microtubule organizing center organization GO:0031023 1 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
Human Rat
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
adult behavior GO:0030534 2 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
growth GO:0040007 174 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
histone modification GO:0016570 20 0.021
meiosis i GO:0007127 1 0.020
response to stress GO:0006950 263 0.020
Human
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
Rat Fly
localization of cell GO:0051674 244 0.020
regulation of molecular function GO:0065009 70 0.020
regulation of protein targeting GO:1903533 2 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.020
dna templated transcription elongation GO:0006354 3 0.020
digestive system development GO:0055123 289 0.020
cellular response to radiation GO:0071478 4 0.020
Human
microtubule polymerization GO:0046785 2 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
Human Rat Fly
protein complex subunit organization GO:0071822 46 0.020
mrna 3 end processing GO:0031124 2 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
Human Rat Fly
leukocyte proliferation GO:0070661 1 0.019
regionalization GO:0003002 274 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
cytoskeleton organization GO:0007010 96 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.019
microtubule based process GO:0007017 60 0.019
regulation of protein depolymerization GO:1901879 1 0.018
histone h3 k4 methylation GO:0051568 2 0.018
transcription dna templated GO:0006351 181 0.018
Human Rat Fly
regulation of intracellular protein transport GO:0033157 3 0.018
regulation of dna replication GO:0006275 3 0.018
lymphocyte proliferation GO:0046651 1 0.018
regulation of reproductive process GO:2000241 4 0.018
macromolecular complex disassembly GO:0032984 1 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
Human Rat Fly
protein acylation GO:0043543 3 0.018
regulation of binding GO:0051098 3 0.018
regulation of catalytic activity GO:0050790 55 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
female gonad development GO:0008585 4 0.017
Human
death GO:0016265 121 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
regulation of protein catabolic process GO:0042176 1 0.017
negative regulation of cell communication GO:0010648 96 0.017
nucleic acid templated transcription GO:0097659 181 0.017
Human Rat Fly
positive regulation of jnk cascade GO:0046330 3 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
nuclear export GO:0051168 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
phosphorus metabolic process GO:0006793 109 0.016
mrna polyadenylation GO:0006378 2 0.016
double strand break repair GO:0006302 3 0.016
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.016
meiosis ii GO:0007135 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
b cell activation GO:0042113 2 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
negative regulation of developmental process GO:0051093 65 0.015
immune system process GO:0002376 241 0.015
astral microtubule organization GO:0030953 1 0.015
primary neural tube formation GO:0014020 1 0.015
rna biosynthetic process GO:0032774 181 0.015
Human Rat Fly
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
Human Rat Fly
transport GO:0006810 220 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
microtubule depolymerization GO:0007019 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
positive regulation of jak stat cascade GO:0046427 2 0.014
negative regulation of nuclear division GO:0051784 3 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
cellular response to nutrient levels GO:0031669 2 0.014
heart development GO:0007507 313 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.014
regulation of circadian rhythm GO:0042752 4 0.014
regulation of microtubule depolymerization GO:0031114 1 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of cellular component organization GO:0051128 86 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
negative regulation of signal transduction GO:0009968 94 0.013
regulation of organelle assembly GO:1902115 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
Human Rat Fly
programmed cell death GO:0012501 119 0.013
negative regulation of kinase activity GO:0033673 4 0.013
response to uv GO:0009411 3 0.013
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
cell morphogenesis GO:0000902 289 0.013
Fly
cellular response to external stimulus GO:0071496 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
positive regulation of cellular process GO:0048522 201 0.013
Rat Fly
protein alkylation GO:0008213 13 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
organic substance biosynthetic process GO:1901576 289 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
macromolecule localization GO:0033036 54 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
positive regulation of embryonic development GO:0040019 3 0.013
cell proliferation GO:0008283 80 0.013
negative regulation of reproductive process GO:2000242 3 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
Human Rat Fly
glucose homeostasis GO:0042593 1 0.012
convergent extension GO:0060026 118 0.012
anterior posterior pattern specification GO:0009952 152 0.012
cellular response to starvation GO:0009267 1 0.012
tube closure GO:0060606 1 0.012
protein heterooligomerization GO:0051291 1 0.012
response to vitamin GO:0033273 3 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
Fly
protein depolymerization GO:0051261 1 0.012
cell projection morphogenesis GO:0048858 244 0.012
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
positive regulation of molecular function GO:0044093 33 0.012
developmental growth GO:0048589 166 0.012
positive regulation of signaling GO:0023056 56 0.012
positive regulation of developmental process GO:0051094 50 0.012
female meiotic division GO:0007143 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
single organism localization GO:1902578 225 0.012
cellular response to organic substance GO:0071310 105 0.012
Rat
protein k63 linked ubiquitination GO:0070534 2 0.011
cellular response to stress GO:0033554 62 0.011
Human
negative regulation of synapse assembly GO:0051964 2 0.011
chemotaxis GO:0006935 104 0.011
nucleic acid metabolic process GO:0090304 244 0.011
Human Rat Fly
embryonic organ morphogenesis GO:0048562 274 0.011
positive regulation of cytokine production GO:0001819 2 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
Human Rat Fly
cellular localization GO:0051641 97 0.011
negative regulation of defense response GO:0031348 2 0.011
protein dephosphorylation GO:0006470 3 0.011
wnt signaling pathway GO:0016055 80 0.011
female sex differentiation GO:0046660 4 0.011
Human
male meiosis GO:0007140 2 0.011
establishment or maintenance of cell polarity GO:0007163 29 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
mitochondrion organization GO:0007005 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
response to monosaccharide GO:0034284 3 0.011
establishment of organelle localization GO:0051656 45 0.011
cell cycle GO:0007049 93 0.011
axonogenesis GO:0007409 152 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
negative regulation of signaling GO:0023057 96 0.011
neuronal stem cell maintenance GO:0097150 2 0.011
membrane invagination GO:0010324 1 0.011
response to carbohydrate GO:0009743 3 0.011
telomere organization GO:0032200 1 0.011
organelle localization GO:0051640 49 0.011
stem cell development GO:0048864 82 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
tissue remodeling GO:0048771 4 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
cellular protein complex disassembly GO:0043624 1 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
protein complex assembly GO:0006461 30 0.011
peptidyl serine modification GO:0018209 2 0.011
actin polymerization or depolymerization GO:0008154 2 0.010
vacuolar transport GO:0007034 2 0.010
dna biosynthetic process GO:0071897 3 0.010
b cell differentiation GO:0030183 1 0.010
regulation of cell cycle GO:0051726 52 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
regulation of protein polymerization GO:0032271 2 0.010
embryonic organ development GO:0048568 381 0.010
protein targeting to membrane GO:0006612 1 0.010
regulation of inflammatory response GO:0050727 2 0.010
spermatid differentiation GO:0048515 2 0.010
mrna metabolic process GO:0016071 20 0.010
somatic muscle development GO:0007525 4 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
Rat Fly
protein complex biogenesis GO:0070271 30 0.010
peptidyl lysine trimethylation GO:0018023 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
cellular macromolecule localization GO:0070727 21 0.010

yy1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.011
nervous system disease DOID:863 0 0.011