Danio rerio

0 known processes

pdzd4

PDZ domain containing 4

(Aliases: im:6912105)

pdzd4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nitrogen compound metabolic process GO:0051171 251 0.087
larval development GO:0002164 2 0.086
cell motility GO:0048870 244 0.077
aging GO:0007568 2 0.077
regulation of multicellular organismal process GO:0051239 277 0.069
nucleic acid metabolic process GO:0090304 244 0.066
rna metabolic process GO:0016070 219 0.064
negative regulation of biological process GO:0048519 304 0.062
rna biosynthetic process GO:0032774 181 0.060
regulation of macromolecule metabolic process GO:0060255 317 0.059
multicellular organism growth GO:0035264 4 0.059
organic cyclic compound metabolic process GO:1901360 301 0.059
nitrogen compound metabolic process GO:0006807 319 0.058
regulation of gene expression GO:0010468 265 0.057
aromatic compound biosynthetic process GO:0019438 217 0.057
regulation of cellular metabolic process GO:0031323 320 0.057
regulation of primary metabolic process GO:0080090 311 0.054
regulation of transcription dna templated GO:0006355 213 0.053
gene expression GO:0010467 252 0.053
transcription dna templated GO:0006351 181 0.052
heterocycle metabolic process GO:0046483 290 0.050
heart development GO:0007507 313 0.049
cellular macromolecule metabolic process GO:0044260 391 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.049
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
regulation of rna biosynthetic process GO:2001141 213 0.048
meiotic nuclear division GO:0007126 4 0.048
macromolecule biosynthetic process GO:0009059 227 0.047
regulation of developmental process GO:0050793 247 0.046
biosynthetic process GO:0009058 294 0.046
nucleobase containing compound biosynthetic process GO:0034654 205 0.046
regulation of metabolic process GO:0019222 359 0.046
morphogenesis of an epithelium GO:0002009 333 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.045
organic substance biosynthetic process GO:1901576 289 0.045
positive regulation of transport GO:0051050 2 0.045
nucleic acid templated transcription GO:0097659 181 0.045
regulation of nucleic acid templated transcription GO:1903506 213 0.044
embryonic organ morphogenesis GO:0048562 274 0.044
localization of cell GO:0051674 244 0.043
heterocycle biosynthetic process GO:0018130 215 0.043
generation of neurons GO:0048699 385 0.043
maintenance of location GO:0051235 4 0.042
neuron differentiation GO:0030182 353 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.042
tube morphogenesis GO:0035239 349 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
regulation of rna metabolic process GO:0051252 224 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.040
embryonic organ development GO:0048568 381 0.040
phagocytosis GO:0006909 3 0.040
regulation of biosynthetic process GO:0009889 250 0.040
regulation of multicellular organism growth GO:0040014 4 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.039
cellular component movement GO:0006928 335 0.039
organic cyclic compound biosynthetic process GO:1901362 223 0.038
regulation of cellular biosynthetic process GO:0031326 245 0.038
regulation of protein transport GO:0051223 3 0.038
head development GO:0060322 303 0.037
regulation of multicellular organismal development GO:2000026 223 0.036
signal transduction GO:0007165 455 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
cell migration GO:0016477 237 0.035
response to external stimulus GO:0009605 264 0.035
vasculature development GO:0001944 278 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
negative regulation of cellular process GO:0048523 283 0.035
lipid storage GO:0019915 1 0.034
central nervous system development GO:0007417 387 0.034
positive regulation of cell cycle GO:0045787 3 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.032
regulation of meiotic cell cycle GO:0051445 1 0.032
brain development GO:0007420 293 0.032
regionalization GO:0003002 274 0.032
establishment of localization GO:0051234 244 0.031
positive regulation of catabolic process GO:0009896 4 0.031
sensory organ development GO:0007423 393 0.031
response to chemical GO:0042221 320 0.031
cell morphogenesis GO:0000902 289 0.030
digestive system development GO:0055123 289 0.030
nuclear transport GO:0051169 4 0.030
determination of bilateral symmetry GO:0009855 204 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
adult behavior GO:0030534 2 0.029
autophagy GO:0006914 4 0.029
cellular component morphogenesis GO:0032989 336 0.029
positive regulation of biological process GO:0048518 253 0.029
cellular amine metabolic process GO:0044106 2 0.029
transcription from rna polymerase ii promoter GO:0006366 80 0.029
cellular response to external stimulus GO:0071496 2 0.029
regulation of mrna processing GO:0050684 3 0.028
locomotion GO:0040011 313 0.028
specification of symmetry GO:0009799 204 0.028
female sex differentiation GO:0046660 4 0.028
amine metabolic process GO:0009308 2 0.028
chordate embryonic development GO:0043009 271 0.027
regulation of protein complex assembly GO:0043254 3 0.026
regulation of cell differentiation GO:0045595 142 0.026
positive regulation of secretion by cell GO:1903532 1 0.026
regulation of cytokine production GO:0001817 3 0.026
immune system process GO:0002376 241 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.025
response to hexose GO:0009746 3 0.025
positive regulation of secretion GO:0051047 1 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
digestive tract development GO:0048565 265 0.024
cellular biosynthetic process GO:0044249 286 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
blood vessel morphogenesis GO:0048514 216 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
regulation of response to stimulus GO:0048583 269 0.024
cellular ketone metabolic process GO:0042180 11 0.024
sensory organ morphogenesis GO:0090596 200 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
developmental growth GO:0048589 166 0.023
camera type eye development GO:0043010 222 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of mrna splicing via spliceosome GO:0048024 3 0.023
alternative mrna splicing via spliceosome GO:0000380 1 0.023
stem cell maintenance GO:0019827 4 0.023
tissue remodeling GO:0048771 4 0.023
regulation of cell activation GO:0050865 1 0.022
response to stress GO:0006950 263 0.022
positive regulation of cell activation GO:0050867 1 0.022
blood vessel development GO:0001568 246 0.022
positive regulation of cellular process GO:0048522 201 0.022
regulation of metal ion transport GO:0010959 4 0.022
protein import GO:0017038 3 0.022
oxoacid metabolic process GO:0043436 31 0.022
neuron projection development GO:0031175 180 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
negative regulation of multicellular organismal process GO:0051241 69 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
regulation of biological quality GO:0065008 263 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
eye development GO:0001654 277 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
protein metabolic process GO:0019538 183 0.021
stem cell proliferation GO:0072089 4 0.021
epithelial tube morphogenesis GO:0060562 148 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
negative regulation of gene expression GO:0010629 65 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
exocytosis GO:0006887 1 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
regulation of reproductive process GO:2000241 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
cellular response to starvation GO:0009267 1 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of cell development GO:0060284 100 0.019
cognition GO:0050890 1 0.019
cellular response to nutrient levels GO:0031669 2 0.019
digestive tract morphogenesis GO:0048546 231 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
carbohydrate homeostasis GO:0033500 1 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
mononuclear cell proliferation GO:0032943 1 0.019
spermatid differentiation GO:0048515 2 0.019
protein secretion GO:0009306 1 0.019
regulation of protein targeting GO:1903533 2 0.019
lipid catabolic process GO:0016042 4 0.019
mitochondrion organization GO:0007005 4 0.018
system process GO:0003008 185 0.018
organelle organization GO:0006996 227 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
single organism localization GO:1902578 225 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
homeostatic process GO:0042592 142 0.018
organic acid metabolic process GO:0006082 31 0.018
gtp metabolic process GO:0046039 4 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
lymphocyte proliferation GO:0046651 1 0.018
protein polymerization GO:0051258 4 0.018
leukocyte proliferation GO:0070661 1 0.018
regulation of signaling GO:0023051 235 0.018
cell projection organization GO:0030030 284 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
cell surface receptor signaling pathway GO:0007166 325 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
nuclear import GO:0051170 3 0.017
regulation of blood pressure GO:0008217 1 0.017
response to uv GO:0009411 3 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
camera type eye morphogenesis GO:0048593 108 0.017
regulation of dendrite development GO:0050773 3 0.017
single organism organelle organization GO:1902589 199 0.017
negative regulation of protein transport GO:0051224 3 0.017
negative regulation of metabolic process GO:0009892 86 0.017
muscle cell development GO:0055001 115 0.017
cellular component assembly GO:0022607 170 0.017
regulation of signal transduction GO:0009966 225 0.017
embryonic heart tube development GO:0035050 133 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
positive regulation of cytokine production GO:0001819 2 0.017
gastrulation GO:0007369 208 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
growth GO:0040007 174 0.016
protein localization to nucleus GO:0034504 3 0.016
negative regulation of transcription dna templated GO:0045892 45 0.016
positive regulation of immune effector process GO:0002699 3 0.016
cell death GO:0008219 121 0.016
determination of left right symmetry GO:0007368 179 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
protein acetylation GO:0006473 2 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
single organism nuclear import GO:1902593 3 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
inner ear development GO:0048839 126 0.015
single organism metabolic process GO:0044710 217 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
retina development in camera type eye GO:0060041 146 0.015
response to carbohydrate GO:0009743 3 0.015
regulation of cell communication GO:0010646 232 0.015
response to drug GO:0042493 3 0.015
cellular amide metabolic process GO:0043603 4 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
ear development GO:0043583 127 0.015
glucose homeostasis GO:0042593 1 0.015
interspecies interaction between organisms GO:0044419 4 0.015
negative regulation of rna metabolic process GO:0051253 48 0.015
response to monosaccharide GO:0034284 3 0.015
ameboidal type cell migration GO:0001667 143 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
cellular component biogenesis GO:0044085 178 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
death GO:0016265 121 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
stem cell fate commitment GO:0048865 1 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
secondary metabolic process GO:0019748 3 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of protein catabolic process GO:0042176 1 0.015
positive regulation of metabolic process GO:0009893 108 0.015
hepaticobiliary system development GO:0061008 98 0.015
hemopoiesis GO:0030097 183 0.014
heart morphogenesis GO:0003007 156 0.014
neuron projection morphogenesis GO:0048812 161 0.014
apical junction assembly GO:0043297 1 0.014
nuclear export GO:0051168 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
muscle structure development GO:0061061 196 0.014
negative regulation of secretion GO:0051048 2 0.014
membrane fusion GO:0061025 2 0.014
regulation of protein polymerization GO:0032271 2 0.014
angiogenesis GO:0001525 158 0.014
regulation of inflammatory response GO:0050727 2 0.014
protein targeting to nucleus GO:0044744 3 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
spermatid development GO:0007286 2 0.014
regulation of neurogenesis GO:0050767 87 0.014
regulation of nervous system development GO:0051960 90 0.014
negative regulation of cytokine production GO:0001818 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
apoptotic process GO:0006915 116 0.014
anterior posterior pattern specification GO:0009952 152 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
transport GO:0006810 220 0.014
skeletal system development GO:0001501 181 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
response to corticosteroid GO:0031960 1 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
convergent extension GO:0060026 118 0.014
peptidyl serine modification GO:0018209 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
melanin metabolic process GO:0006582 2 0.014
regulation of autophagy GO:0010506 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
regulation of muscle contraction GO:0006937 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
membrane invagination GO:0010324 1 0.013
meiotic cell cycle process GO:1903046 3 0.013
response to ketone GO:1901654 1 0.013
gland development GO:0048732 143 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
immune system development GO:0002520 191 0.013
negative regulation of kinase activity GO:0033673 4 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
blood circulation GO:0008015 87 0.013
small molecule metabolic process GO:0044281 77 0.013
female gonad development GO:0008585 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
protein stabilization GO:0050821 2 0.013
multi organism process GO:0051704 134 0.013
phagocytosis engulfment GO:0006911 1 0.013
somite development GO:0061053 96 0.013
neuron development GO:0048666 262 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
heart looping GO:0001947 94 0.013
regulation of synapse organization GO:0050807 3 0.013
startle response GO:0001964 4 0.013
hormone secretion GO:0046879 2 0.013
macromolecule modification GO:0043412 111 0.013
negative regulation of defense response GO:0031348 2 0.013
muscle tissue development GO:0060537 110 0.013
liver development GO:0001889 96 0.013
fertilization GO:0009566 3 0.013
muscle cell differentiation GO:0042692 139 0.013
hormone transport GO:0009914 2 0.013
small molecule catabolic process GO:0044282 3 0.013
muscle organ development GO:0007517 101 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.012
single organism transport GO:0044765 206 0.012
chemosensory behavior GO:0007635 1 0.012
b cell activation GO:0042113 2 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
compound eye development GO:0048749 2 0.012
locomotor rhythm GO:0045475 3 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
mitotic cell cycle GO:0000278 64 0.012
regulation of neuron differentiation GO:0045664 56 0.012
peptide transport GO:0015833 1 0.012
cell cycle GO:0007049 93 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
regulation of sodium ion transport GO:0002028 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
skeletal muscle organ development GO:0060538 78 0.012
endosomal transport GO:0016197 2 0.012
cytokinesis GO:0000910 3 0.012
striated muscle tissue development GO:0014706 110 0.012
lipid homeostasis GO:0055088 3 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
neurological system process GO:0050877 62 0.012
neuroblast proliferation GO:0007405 2 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
cellular protein metabolic process GO:0044267 129 0.012
mesoderm development GO:0007498 88 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of hormone secretion GO:0046883 2 0.011
hindbrain development GO:0030902 91 0.011
response to wounding GO:0009611 116 0.011
antimicrobial humoral response GO:0019730 2 0.011
response to biotic stimulus GO:0009607 97 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
response to nutrient GO:0007584 3 0.011
cellular response to radiation GO:0071478 4 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of exocytosis GO:0017157 1 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
segmentation GO:0035282 97 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
amino acid transport GO:0006865 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
meiotic chromosome segregation GO:0045132 3 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of tube size GO:0035150 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
activation of mapk activity GO:0000187 3 0.011
germ line stem cell maintenance GO:0030718 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
transmembrane transport GO:0055085 120 0.011
mesenchyme development GO:0060485 127 0.011
programmed cell death GO:0012501 119 0.011
cell fate specification GO:0001708 68 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
protein modification process GO:0036211 100 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
positive regulation of gene expression GO:0010628 71 0.011
actin filament polymerization GO:0030041 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
single fertilization GO:0007338 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
cellular localization GO:0051641 97 0.011
cytoplasm organization GO:0007028 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
cellular response to light stimulus GO:0071482 4 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
gastrulation with mouth forming second GO:0001702 44 0.010
neurotransmitter transport GO:0006836 2 0.010
regulation of membrane potential GO:0042391 23 0.010
cell cycle arrest GO:0007050 1 0.010
axon development GO:0061564 166 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
single organism membrane fusion GO:0044801 2 0.010
regulation of gtpase activity GO:0043087 2 0.010
striated muscle cell differentiation GO:0051146 129 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
negative regulation of developmental process GO:0051093 65 0.010
post embryonic organ development GO:0048569 4 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
cellular protein modification process GO:0006464 100 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
developmental programmed cell death GO:0010623 4 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
positive regulation of reproductive process GO:2000243 2 0.010
cell differentiation in spinal cord GO:0021515 40 0.010
establishment of localization in cell GO:0051649 77 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
atp catabolic process GO:0006200 4 0.010
spinal cord development GO:0021510 46 0.010

pdzd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
musculoskeletal system disease DOID:17 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.011