Danio rerio

0 known processes

igf2r

insulin-like growth factor 2 receptor

(Aliases: si:ch211-214g8.2)

igf2r biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.256
cell migration GO:0016477 237 0.155
locomotion GO:0040011 313 0.145
embryonic organ morphogenesis GO:0048562 274 0.145
larval development GO:0002164 2 0.138
positive regulation of biological process GO:0048518 253 0.130
aging GO:0007568 2 0.125
localization of cell GO:0051674 244 0.121
morphogenesis of an epithelium GO:0002009 333 0.120
startle response GO:0001964 4 0.115
cell motility GO:0048870 244 0.112
vacuolar transport GO:0007034 2 0.103
maintenance of location GO:0051235 4 0.100
regulation of multicellular organism growth GO:0040014 4 0.099
negative regulation of biological process GO:0048519 304 0.096
hematopoietic or lymphoid organ development GO:0048534 191 0.096
gastrulation GO:0007369 208 0.095
lipid storage GO:0019915 1 0.088
head development GO:0060322 303 0.081
neuron differentiation GO:0030182 353 0.076
immune system development GO:0002520 191 0.074
brain development GO:0007420 293 0.074
sensory organ development GO:0007423 393 0.074
regulation of reproductive process GO:2000241 4 0.073
cellular component movement GO:0006928 335 0.072
regulation of localization GO:0032879 104 0.071
regulation of biological quality GO:0065008 263 0.067
establishment of protein localization to organelle GO:0072594 4 0.065
generation of neurons GO:0048699 385 0.063
tube morphogenesis GO:0035239 349 0.062
cognition GO:0050890 1 0.061
establishment of localization GO:0051234 244 0.059
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.058
cell projection morphogenesis GO:0048858 244 0.057
central nervous system development GO:0007417 387 0.056
cardiac muscle tissue development GO:0048738 48 0.056
aromatic compound biosynthetic process GO:0019438 217 0.055
glial cell migration GO:0008347 3 0.055
regulation of multicellular organismal process GO:0051239 277 0.054
phosphate containing compound metabolic process GO:0006796 108 0.053
digestive tract development GO:0048565 265 0.053
establishment of localization in cell GO:0051649 77 0.050
ameboidal type cell migration GO:0001667 143 0.050
cell cycle g1 s phase transition GO:0044843 1 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.049
heterocycle metabolic process GO:0046483 290 0.049
regulation of meiotic cell cycle GO:0051445 1 0.048
cellular macromolecule metabolic process GO:0044260 391 0.048
proteasomal protein catabolic process GO:0010498 2 0.047
transport GO:0006810 220 0.047
digestive system development GO:0055123 289 0.047
regulation of cell development GO:0060284 100 0.046
g1 s transition of mitotic cell cycle GO:0000082 1 0.046
immune system process GO:0002376 241 0.045
regulation of circadian rhythm GO:0042752 4 0.045
lysosomal transport GO:0007041 2 0.044
positive regulation of cell cycle GO:0045787 3 0.044
oxoacid metabolic process GO:0043436 31 0.044
chordate embryonic development GO:0043009 271 0.043
cellular component morphogenesis GO:0032989 336 0.042
cellular protein modification process GO:0006464 100 0.042
positive regulation of transport GO:0051050 2 0.042
macromolecule modification GO:0043412 111 0.042
system process GO:0003008 185 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.041
protein metabolic process GO:0019538 183 0.040
cell morphogenesis involved in differentiation GO:0000904 195 0.039
multicellular organism growth GO:0035264 4 0.038
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
protein modification process GO:0036211 100 0.037
cellular protein catabolic process GO:0044257 4 0.037
protein localization to nucleus GO:0034504 3 0.037
hemopoiesis GO:0030097 183 0.037
organic acid metabolic process GO:0006082 31 0.037
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
neuron projection morphogenesis GO:0048812 161 0.036
regulation of epithelial cell proliferation GO:0050678 3 0.035
epithelial tube morphogenesis GO:0060562 148 0.034
cell projection organization GO:0030030 284 0.034
cell cycle arrest GO:0007050 1 0.034
neurological system process GO:0050877 62 0.034
small molecule metabolic process GO:0044281 77 0.034
meiotic cell cycle process GO:1903046 3 0.034
heart development GO:0007507 313 0.033
signal transduction GO:0007165 455 0.033
cellular component disassembly GO:0022411 1 0.033
single organism cellular localization GO:1902580 46 0.032
programmed cell death GO:0012501 119 0.031
peptide transport GO:0015833 1 0.031
mitotic cell cycle process GO:1903047 48 0.031
regulation of filopodium assembly GO:0051489 2 0.031
regulation of response to stimulus GO:0048583 269 0.030
mesenchymal cell differentiation GO:0048762 87 0.030
organic substance biosynthetic process GO:1901576 289 0.030
negative regulation of cellular process GO:0048523 283 0.029
meiotic nuclear division GO:0007126 4 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.028
axon development GO:0061564 166 0.028
positive regulation of wound healing GO:0090303 1 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.028
single organism transport GO:0044765 206 0.028
regulation of protein transport GO:0051223 3 0.027
organic substance transport GO:0071702 58 0.027
positive regulation of metabolic process GO:0009893 108 0.027
b cell activation GO:0042113 2 0.027
cell morphogenesis GO:0000902 289 0.027
adult behavior GO:0030534 2 0.026
embryonic heart tube morphogenesis GO:0003143 108 0.025
regulation of binding GO:0051098 3 0.025
nuclear transport GO:0051169 4 0.025
establishment of nucleus localization GO:0040023 7 0.025
response to chemical GO:0042221 320 0.024
protein targeting to vacuole GO:0006623 1 0.024
regulation of cell shape GO:0008360 1 0.024
neural crest cell migration GO:0001755 42 0.024
stem cell differentiation GO:0048863 117 0.024
apoptotic process GO:0006915 116 0.024
mitotic dna integrity checkpoint GO:0044774 4 0.024
neuron development GO:0048666 262 0.024
regulation of cellular component organization GO:0051128 86 0.023
digestive tract morphogenesis GO:0048546 231 0.023
protein import GO:0017038 3 0.023
response to external stimulus GO:0009605 264 0.023
negative regulation of reproductive process GO:2000242 3 0.023
nuclear import GO:0051170 3 0.023
nuclear migration GO:0007097 3 0.023
mitotic g2 m transition checkpoint GO:0044818 3 0.023
regulation of metabolic process GO:0019222 359 0.022
axonogenesis GO:0007409 152 0.022
skeletal system morphogenesis GO:0048705 102 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
single organism organelle organization GO:1902589 199 0.022
regulation of cellular component movement GO:0051270 55 0.022
cellular protein metabolic process GO:0044267 129 0.022
embryonic skeletal system development GO:0048706 97 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.021
positive regulation of stress activated mapk cascade GO:0032874 3 0.021
forebrain cell migration GO:0021885 1 0.021
embryonic heart tube development GO:0035050 133 0.021
ventricular cardiac muscle tissue development GO:0003229 3 0.021
transcription dna templated GO:0006351 181 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
cellular biosynthetic process GO:0044249 286 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
striated muscle cell development GO:0055002 108 0.021
rna biosynthetic process GO:0032774 181 0.021
negative regulation of protein kinase activity GO:0006469 4 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
embryonic digestive tract development GO:0048566 4 0.020
embryonic cranial skeleton morphogenesis GO:0048701 90 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
response to glucocorticoid GO:0051384 1 0.020
regulation of synapse assembly GO:0051963 3 0.020
behavior GO:0007610 74 0.020
digestive tract mesoderm development GO:0007502 1 0.020
homeostasis of number of cells GO:0048872 62 0.020
amine metabolic process GO:0009308 2 0.020
response to stress GO:0006950 263 0.020
gliogenesis GO:0042063 45 0.019
regulation of dendrite development GO:0050773 3 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of cell communication GO:0010646 232 0.019
actin cytoskeleton organization GO:0030036 63 0.019
regulation of cell projection assembly GO:0060491 4 0.019
wnt signaling pathway GO:0016055 80 0.019
locomotor rhythm GO:0045475 3 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
meiosis i GO:0007127 1 0.019
regulation of metal ion transport GO:0010959 4 0.019
response to wounding GO:0009611 116 0.018
cell cycle GO:0007049 93 0.018
regulation of primary metabolic process GO:0080090 311 0.018
stem cell proliferation GO:0072089 4 0.018
leukocyte homeostasis GO:0001776 2 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cell proliferation GO:0008283 80 0.018
regulation of synapse organization GO:0050807 3 0.018
organelle fusion GO:0048284 3 0.018
heart looping GO:0001947 94 0.018
regulation of neuron differentiation GO:0045664 56 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
protein polymerization GO:0051258 4 0.017
mesenchyme development GO:0060485 127 0.017
response to uv GO:0009411 3 0.017
protein targeting to nucleus GO:0044744 3 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
homeostatic process GO:0042592 142 0.017
oocyte maturation GO:0001556 4 0.017
estrogen metabolic process GO:0008210 2 0.017
regulation of protein binding GO:0043393 3 0.016
axon ensheathment in central nervous system GO:0032291 2 0.016
negative regulation of protein transport GO:0051224 3 0.016
macromolecule localization GO:0033036 54 0.016
skin development GO:0043588 54 0.016
cell cycle process GO:0022402 53 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
muscle structure development GO:0061061 196 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
negative regulation of gliogenesis GO:0014014 1 0.016
single organism localization GO:1902578 225 0.016
single organism reproductive process GO:0044702 40 0.016
nucleic acid templated transcription GO:0097659 181 0.016
regulation of cell differentiation GO:0045595 142 0.016
single organism membrane fusion GO:0044801 2 0.016
single organism metabolic process GO:0044710 217 0.016
organism emergence from protective structure GO:0071684 4 0.016
cell part morphogenesis GO:0032990 246 0.016
regulation of developmental growth GO:0048638 38 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
nitrogen compound metabolic process GO:0006807 319 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
rna metabolic process GO:0016070 219 0.015
sensory organ morphogenesis GO:0090596 200 0.015
lipid homeostasis GO:0055088 3 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
cellular ketone metabolic process GO:0042180 11 0.015
striated muscle tissue development GO:0014706 110 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
organelle organization GO:0006996 227 0.015
mesenchymal cell development GO:0014031 78 0.015
regulation of nervous system development GO:0051960 90 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
exocytosis GO:0006887 1 0.015
regulation of wound healing GO:0061041 2 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
cellular localization GO:0051641 97 0.015
regulation of membrane potential GO:0042391 23 0.015
muscle cell development GO:0055001 115 0.015
centrosome organization GO:0051297 1 0.015
regulation of cell migration GO:0030334 40 0.015
stem cell maintenance GO:0019827 4 0.015
keratinocyte differentiation GO:0030216 0 0.015
protein dephosphorylation GO:0006470 3 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
carbohydrate derivative biosynthetic process GO:1901137 43 0.014
astrocyte differentiation GO:0048708 1 0.014
phagocytosis GO:0006909 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
regulation of neurogenesis GO:0050767 87 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
cell aging GO:0007569 2 0.014
ear development GO:0043583 127 0.014
epidermal cell fate specification GO:0009957 4 0.014
cytoskeleton organization GO:0007010 96 0.014
epidermal cell differentiation GO:0009913 36 0.014
negative regulation of catabolic process GO:0009895 3 0.014
neuron projection development GO:0031175 180 0.014
myeloid cell homeostasis GO:0002262 56 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
lipid metabolic process GO:0006629 52 0.013
regulation of oocyte development GO:0060281 3 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
ear morphogenesis GO:0042471 64 0.013
ras protein signal transduction GO:0007265 7 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
gene expression GO:0010467 252 0.013
convergent extension GO:0060026 118 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
response to corticosteroid GO:0031960 1 0.013
meiotic spindle organization GO:0000212 1 0.013
sulfur compound biosynthetic process GO:0044272 9 0.013
heart morphogenesis GO:0003007 156 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
growth GO:0040007 174 0.013
glycoprotein biosynthetic process GO:0009101 21 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
meiotic chromosome segregation GO:0045132 3 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of cardiac muscle tissue development GO:0055024 1 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of growth GO:0040008 42 0.013
regulation of glial cell differentiation GO:0045685 4 0.013
regulation of gene expression GO:0010468 265 0.013
monocarboxylic acid biosynthetic process GO:0072330 12 0.013
regulation of apoptotic process GO:0042981 98 0.013
muscle cell differentiation GO:0042692 139 0.013
response to drug GO:0042493 3 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
regulation of programmed cell death GO:0043067 101 0.013
wound healing GO:0042060 90 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
axon extension GO:0048675 45 0.013
mitotic nuclear division GO:0007067 18 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
protein localization to vacuole GO:0072665 1 0.012
water homeostasis GO:0030104 4 0.012
homologous chromosome segregation GO:0045143 1 0.012
regulation of protein complex assembly GO:0043254 3 0.012
protein phosphorylation GO:0006468 47 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
regulation of cell cycle GO:0051726 52 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
tube closure GO:0060606 1 0.012
gland development GO:0048732 143 0.012
neuroblast proliferation GO:0007405 2 0.012
mitotic cell cycle GO:0000278 64 0.012
positive regulation of neuron death GO:1901216 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
skeletal system development GO:0001501 181 0.012
cellular amine metabolic process GO:0044106 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
neuron projection guidance GO:0097485 86 0.012
nucleic acid metabolic process GO:0090304 244 0.012
response to nutrient GO:0007584 3 0.012
compound eye development GO:0048749 2 0.012
multi organism process GO:0051704 134 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
positive regulation of map kinase activity GO:0043406 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of cell activation GO:0050865 1 0.011
positive regulation of secretion GO:0051047 1 0.011
positive regulation of exocytosis GO:0045921 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of transcription dna templated GO:0006355 213 0.011
positive regulation of cellular process GO:0048522 201 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
regulation of cell motility GO:2000145 46 0.011
taxis GO:0042330 109 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of cell proliferation GO:0042127 37 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
olfactory lobe development GO:0021988 4 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
inner ear development GO:0048839 126 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
response to monosaccharide GO:0034284 3 0.011
erythrocyte homeostasis GO:0034101 55 0.011
central nervous system neuron axonogenesis GO:0021955 18 0.010
cellular lipid metabolic process GO:0044255 36 0.010
hormone secretion GO:0046879 2 0.010
cell substrate junction assembly GO:0007044 2 0.010
membrane fusion GO:0061025 2 0.010
regulation of muscle contraction GO:0006937 3 0.010
regulation of nitrogen compound metabolic process GO:0051171 251 0.010
cell fate commitment GO:0045165 99 0.010
erythrocyte differentiation GO:0030218 54 0.010
muscle tissue development GO:0060537 110 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
endocardial cushion formation GO:0003272 2 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
protein localization GO:0008104 40 0.010
regulation of cytokine production GO:0001817 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010

igf2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.014
cardiovascular system disease DOID:1287 0 0.012
disease of metabolism DOID:0014667 0 0.011
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011