Danio rerio

0 known processes

si:ch211-221n23.1

si:ch211-221n23.1

(Aliases: znf238)

si:ch211-221n23.1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell surface receptor signaling pathway GO:0007166 325 0.075
larval development GO:0002164 2 0.069
nucleic acid metabolic process GO:0090304 244 0.061
signal transduction GO:0007165 455 0.056
regulation of developmental process GO:0050793 247 0.056
multicellular organism growth GO:0035264 4 0.054
regulation of multicellular organism growth GO:0040014 4 0.053
aging GO:0007568 2 0.053
cellular aromatic compound metabolic process GO:0006725 295 0.053
maintenance of location GO:0051235 4 0.052
cellular nitrogen compound metabolic process GO:0034641 290 0.052
cellular macromolecule metabolic process GO:0044260 391 0.051
gene expression GO:0010467 252 0.050
stem cell maintenance GO:0019827 4 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.047
heterocycle metabolic process GO:0046483 290 0.043
morphogenesis of an epithelium GO:0002009 333 0.042
specification of symmetry GO:0009799 204 0.040
regulation of gene expression GO:0010468 265 0.040
regulation of multicellular organismal process GO:0051239 277 0.040
heart development GO:0007507 313 0.040
nitrogen compound metabolic process GO:0006807 319 0.039
macromolecule biosynthetic process GO:0009059 227 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.039
positive regulation of biological process GO:0048518 253 0.039
biosynthetic process GO:0009058 294 0.038
positive regulation of catabolic process GO:0009896 4 0.038
negative regulation of biological process GO:0048519 304 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
negative regulation of cellular process GO:0048523 283 0.037
chordate embryonic development GO:0043009 271 0.036
regulation of primary metabolic process GO:0080090 311 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.034
meiotic nuclear division GO:0007126 4 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
embryonic organ development GO:0048568 381 0.034
organic substance biosynthetic process GO:1901576 289 0.034
sensory organ development GO:0007423 393 0.034
cell part morphogenesis GO:0032990 246 0.033
amine metabolic process GO:0009308 2 0.033
regulation of circadian rhythm GO:0042752 4 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
central nervous system development GO:0007417 387 0.032
cellular protein catabolic process GO:0044257 4 0.032
heterocycle biosynthetic process GO:0018130 215 0.032
neuron differentiation GO:0030182 353 0.032
immune system development GO:0002520 191 0.032
nucleic acid templated transcription GO:0097659 181 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
rna metabolic process GO:0016070 219 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.031
regulation of cytokine production GO:0001817 3 0.031
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.030
organic cyclic compound metabolic process GO:1901360 301 0.030
cellular amine metabolic process GO:0044106 2 0.030
proteasomal protein catabolic process GO:0010498 2 0.029
eye development GO:0001654 277 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
head development GO:0060322 303 0.029
regulation of metabolic process GO:0019222 359 0.028
regulation of response to stimulus GO:0048583 269 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
regulation of rna metabolic process GO:0051252 224 0.028
cellular biosynthetic process GO:0044249 286 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.028
transcription dna templated GO:0006351 181 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
cellular component movement GO:0006928 335 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
mitochondrion organization GO:0007005 4 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
nucleocytoplasmic transport GO:0006913 4 0.026
lipid storage GO:0019915 1 0.026
somatic muscle development GO:0007525 4 0.026
generation of neurons GO:0048699 385 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
nuclear transport GO:0051169 4 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of signal transduction GO:0009966 225 0.025
positive regulation of transport GO:0051050 2 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
locomotion GO:0040011 313 0.025
regulation of stem cell differentiation GO:2000736 4 0.025
meiotic cell cycle process GO:1903046 3 0.025
cognition GO:0050890 1 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
single organism localization GO:1902578 225 0.024
mesenchyme development GO:0060485 127 0.024
muscle structure development GO:0061061 196 0.024
regulation of biological quality GO:0065008 263 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
determination of bilateral symmetry GO:0009855 204 0.024
regulation of cell differentiation GO:0045595 142 0.024
response to chemical GO:0042221 320 0.024
regulation of binding GO:0051098 3 0.024
cellular ketone metabolic process GO:0042180 11 0.023
sensory organ morphogenesis GO:0090596 200 0.023
protein localization to nucleus GO:0034504 3 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
positive regulation of biosynthetic process GO:0009891 68 0.023
retina development in camera type eye GO:0060041 146 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
gtp metabolic process GO:0046039 4 0.022
cellular component morphogenesis GO:0032989 336 0.022
intracellular signal transduction GO:0035556 85 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
camera type eye development GO:0043010 222 0.022
adult behavior GO:0030534 2 0.022
regulation of biosynthetic process GO:0009889 250 0.022
exocytosis GO:0006887 1 0.021
cell substrate adhesion GO:0031589 4 0.021
phagocytosis GO:0006909 3 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
regulation of protein transport GO:0051223 3 0.021
positive regulation of cell cycle GO:0045787 3 0.021
cell migration GO:0016477 237 0.021
response to hexose GO:0009746 3 0.021
neuron development GO:0048666 262 0.021
regulation of cell shape GO:0008360 1 0.021
regionalization GO:0003002 274 0.021
stem cell differentiation GO:0048863 117 0.021
regulation of synapse assembly GO:0051963 3 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.020
hemopoiesis GO:0030097 183 0.020
rna biosynthetic process GO:0032774 181 0.020
regulation of protein catabolic process GO:0042176 1 0.019
cell projection organization GO:0030030 284 0.019
germ line stem cell maintenance GO:0030718 2 0.019
regulation of inflammatory response GO:0050727 2 0.019
cell projection morphogenesis GO:0048858 244 0.019
developmental growth GO:0048589 166 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
single organism organelle organization GO:1902589 199 0.019
transport GO:0006810 220 0.019
ribosomal small subunit biogenesis GO:0042274 2 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of cell death GO:0010941 103 0.019
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
brain development GO:0007420 293 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
protein metabolic process GO:0019538 183 0.018
positive regulation of cellular process GO:0048522 201 0.018
regulation of transcription dna templated GO:0006355 213 0.018
growth GO:0040007 174 0.018
regulation of endocrine process GO:0044060 2 0.018
single organism transport GO:0044765 206 0.018
oocyte maturation GO:0001556 4 0.018
establishment of localization GO:0051234 244 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
stem cell development GO:0048864 82 0.018
meiotic chromosome segregation GO:0045132 3 0.018
response to external stimulus GO:0009605 264 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of synapse organization GO:0050807 3 0.017
blood vessel development GO:0001568 246 0.017
nuclear import GO:0051170 3 0.017
response to stress GO:0006950 263 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
single organism metabolic process GO:0044710 217 0.017
cellular protein metabolic process GO:0044267 129 0.017
ventricular cardiac muscle tissue development GO:0003229 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
cell motility GO:0048870 244 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
gtp catabolic process GO:0006184 2 0.017
oxoacid metabolic process GO:0043436 31 0.017
secondary metabolic process GO:0019748 3 0.017
negative regulation of dna metabolic process GO:0051053 4 0.017
cell morphogenesis GO:0000902 289 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
ovulation cycle process GO:0022602 2 0.017
response to carbohydrate GO:0009743 3 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
positive regulation of translation GO:0045727 1 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
microtubule organizing center organization GO:0031023 1 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
positive regulation of immune effector process GO:0002699 3 0.016
nephron morphogenesis GO:0072028 2 0.016
regulation of signaling GO:0023051 235 0.016
tube morphogenesis GO:0035239 349 0.016
female sex differentiation GO:0046660 4 0.016
digestive tract morphogenesis GO:0048546 231 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
wnt signaling pathway GO:0016055 80 0.016
compound eye development GO:0048749 2 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
synaptic target recognition GO:0008039 1 0.016
centrosome organization GO:0051297 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
skeletal system morphogenesis GO:0048705 102 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
stem cell proliferation GO:0072089 4 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
protein import GO:0017038 3 0.015
regulation of dendrite development GO:0050773 3 0.015
positive regulation of cytokine production GO:0001819 2 0.015
cellular localization GO:0051641 97 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
cellular amide metabolic process GO:0043603 4 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
golgi vesicle transport GO:0048193 3 0.015
regulation of mrna processing GO:0050684 3 0.015
digestive system development GO:0055123 289 0.015
microtubule based movement GO:0007018 33 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
convergent extension GO:0060026 118 0.015
cell death GO:0008219 121 0.015
positive regulation of cell division GO:0051781 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of cell communication GO:0010646 232 0.015
septum transversum development GO:0003343 4 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
multi organism cellular process GO:0044764 2 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
single organism nuclear import GO:1902593 3 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
hormone transport GO:0009914 2 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
membrane invagination GO:0010324 1 0.014
lamellipodium organization GO:0097581 1 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
female gonad development GO:0008585 4 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
small molecule metabolic process GO:0044281 77 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
spermatid development GO:0007286 2 0.014
death GO:0016265 121 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
positive regulation of gene expression GO:0010628 71 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
regulation of protein binding GO:0043393 3 0.014
interspecies interaction between organisms GO:0044419 4 0.014
localization of cell GO:0051674 244 0.014
regulation of cell activation GO:0050865 1 0.014
positive regulation of metabolic process GO:0009893 108 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
hormone secretion GO:0046879 2 0.014
positive regulation of inflammatory response GO:0050729 1 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
atp catabolic process GO:0006200 4 0.014
autophagy GO:0006914 4 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
phagocytosis engulfment GO:0006911 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
negative regulation of kinase activity GO:0033673 4 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
eye morphogenesis GO:0048592 144 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
negative regulation of cytokine production GO:0001818 1 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
negative regulation of catabolic process GO:0009895 3 0.013
organelle organization GO:0006996 227 0.013
rna localization GO:0006403 4 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
lipid catabolic process GO:0016042 4 0.013
immune system process GO:0002376 241 0.013
glucose homeostasis GO:0042593 1 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
camera type eye morphogenesis GO:0048593 108 0.013
regulation of hormone secretion GO:0046883 2 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
cellular component biogenesis GO:0044085 178 0.013
macromolecule modification GO:0043412 111 0.013
response to drug GO:0042493 3 0.013
cell matrix adhesion GO:0007160 4 0.013
cilium movement GO:0003341 26 0.013
protein import into nucleus GO:0006606 3 0.013
tissue remodeling GO:0048771 4 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
regulation of gtpase activity GO:0043087 2 0.013
ameboidal type cell migration GO:0001667 143 0.013
adherens junction organization GO:0034332 4 0.013
peptide transport GO:0015833 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
skeletal system development GO:0001501 181 0.013
positive regulation of secretion GO:0051047 1 0.013
gastrulation GO:0007369 208 0.013
rna export from nucleus GO:0006405 1 0.013
vasculature development GO:0001944 278 0.013
cellular response to external stimulus GO:0071496 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
peptide metabolic process GO:0006518 1 0.012
neural retina development GO:0003407 49 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
response to monosaccharide GO:0034284 3 0.012
negative regulation of developmental process GO:0051093 65 0.012
regulation of blood pressure GO:0008217 1 0.012
tube closure GO:0060606 1 0.012
response to uv GO:0009411 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
apoptotic process GO:0006915 116 0.012
determination of left right symmetry GO:0007368 179 0.012
muscle cell differentiation GO:0042692 139 0.012
nuclear export GO:0051168 1 0.012
centrosome cycle GO:0007098 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cilium organization GO:0044782 71 0.012
cell fate commitment GO:0045165 99 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
somitogenesis GO:0001756 87 0.012
embryonic skeletal system development GO:0048706 97 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
renal tubule morphogenesis GO:0061333 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
viral process GO:0016032 1 0.011
primary neural tube formation GO:0014020 1 0.011
system process GO:0003008 185 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
mitochondrial transport GO:0006839 2 0.011
cellular response to starvation GO:0009267 1 0.011
digestive tract development GO:0048565 265 0.011
organic acid metabolic process GO:0006082 31 0.011
negative regulation of protein transport GO:0051224 3 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
response to alkaloid GO:0043279 2 0.011
regulation of neurogenesis GO:0050767 87 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
leukocyte proliferation GO:0070661 1 0.011
protein stabilization GO:0050821 2 0.011
angiogenesis GO:0001525 158 0.011
response to organic substance GO:0010033 153 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
cellular component assembly GO:0022607 170 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
regulation of neuron differentiation GO:0045664 56 0.011
regulation of protein targeting GO:1903533 2 0.011
rna modification GO:0009451 2 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
startle response GO:0001964 4 0.011
spermatid differentiation GO:0048515 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of oocyte development GO:0060281 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
developmental programmed cell death GO:0010623 4 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
cellular protein modification process GO:0006464 100 0.011
response to glucose GO:0009749 3 0.011
programmed cell death GO:0012501 119 0.011
negative regulation of signaling GO:0023057 96 0.011
glial cell migration GO:0008347 3 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
b cell activation GO:0042113 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
endocrine process GO:0050886 2 0.011
cellular component disassembly GO:0022411 1 0.010
regulation of protein complex assembly GO:0043254 3 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
cellular response to nutrient levels GO:0031669 2 0.010
embryonic heart tube development GO:0035050 133 0.010
regulation of programmed cell death GO:0043067 101 0.010
neuron projection development GO:0031175 180 0.010
response to biotic stimulus GO:0009607 97 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of multi organism process GO:0043902 3 0.010
protein localization to plasma membrane GO:0072659 1 0.010
amino acid transport GO:0006865 2 0.010
protein targeting to membrane GO:0006612 1 0.010
protein dephosphorylation GO:0006470 3 0.010
embryonic skeletal joint development GO:0072498 3 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
post embryonic organ development GO:0048569 4 0.010
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
peptidyl serine modification GO:0018209 2 0.010
regulation of cell development GO:0060284 100 0.010
hepaticobiliary system development GO:0061008 98 0.010
cell killing GO:0001906 2 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cellular lipid catabolic process GO:0044242 3 0.010
cilium morphogenesis GO:0060271 85 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
endosomal transport GO:0016197 2 0.010

si:ch211-221n23.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
immune system disease DOID:2914 0 0.014
nervous system disease DOID:863 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011