Danio rerio

0 known processes

lrrk2

leucine-rich repeat kinase 2

lrrk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.112
maintenance of location GO:0051235 4 0.092
aging GO:0007568 2 0.079
generation of neurons GO:0048699 385 0.073
Mouse Worm
response to stress GO:0006950 263 0.066
Worm
positive regulation of transport GO:0051050 2 0.057
heterocycle metabolic process GO:0046483 290 0.057
cognition GO:0050890 1 0.055
response to drug GO:0042493 3 0.055
rna metabolic process GO:0016070 219 0.054
multicellular organism growth GO:0035264 4 0.054
leukocyte proliferation GO:0070661 1 0.052
amine metabolic process GO:0009308 2 0.051
i kappab kinase nf kappab signaling GO:0007249 4 0.048
central nervous system development GO:0007417 387 0.048
cellular amine metabolic process GO:0044106 2 0.048
neuron development GO:0048666 262 0.047
Mouse Worm
negative regulation of biological process GO:0048519 304 0.046
Mouse
phagocytosis GO:0006909 3 0.046
embryonic organ development GO:0048568 381 0.045
regulation of macromolecule biosynthetic process GO:0010556 225 0.045
lipid storage GO:0019915 1 0.043
cellular nitrogen compound metabolic process GO:0034641 290 0.043
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.043
cellular response to external stimulus GO:0071496 2 0.043
positive regulation of secretion by cell GO:1903532 1 0.043
organelle organization GO:0006996 227 0.043
regulation of metabolic process GO:0019222 359 0.042
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.042
organic cyclic compound metabolic process GO:1901360 301 0.042
head development GO:0060322 303 0.042
mononuclear cell proliferation GO:0032943 1 0.041
cellular macromolecule metabolic process GO:0044260 391 0.040
Mouse
establishment of localization GO:0051234 244 0.040
Mouse Worm
nuclear migration GO:0007097 3 0.039
nucleic acid metabolic process GO:0090304 244 0.039
cellular response to nutrient levels GO:0031669 2 0.039
positive regulation of cell cycle GO:0045787 3 0.039
heterocycle biosynthetic process GO:0018130 215 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
chordate embryonic development GO:0043009 271 0.037
single organism transport GO:0044765 206 0.037
Mouse Worm
signal transduction GO:0007165 455 0.037
Mouse
positive regulation of secretion GO:0051047 1 0.037
regulation of cytokine production GO:0001817 3 0.036
regulation of cell communication GO:0010646 232 0.036
Mouse
transcription dna templated GO:0006351 181 0.036
gene expression GO:0010467 252 0.036
response to chemical GO:0042221 320 0.036
Worm
regulation of establishment of protein localization GO:0070201 4 0.036
stem cell proliferation GO:0072089 4 0.035
regulation of primary metabolic process GO:0080090 311 0.035
Mouse
cellular component movement GO:0006928 335 0.035
Worm
regulation of rna metabolic process GO:0051252 224 0.034
regulation of protein complex assembly GO:0043254 3 0.034
regulation of response to stimulus GO:0048583 269 0.034
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.034
Mouse
regulation of intracellular protein transport GO:0033157 3 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
negative regulation of catabolic process GO:0009895 3 0.034
lipid catabolic process GO:0016042 4 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
regulation of biological quality GO:0065008 263 0.033
Mouse
hemopoiesis GO:0030097 183 0.033
neuron neuron synaptic transmission GO:0007270 1 0.032
Mouse
organic substance biosynthetic process GO:1901576 289 0.032
sensory organ development GO:0007423 393 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
Mouse
cellular protein catabolic process GO:0044257 4 0.032
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
organelle fusion GO:0048284 3 0.032
positive regulation of catabolic process GO:0009896 4 0.031
Mouse
transport GO:0006810 220 0.031
Mouse Worm
positive regulation of cell activation GO:0050867 1 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
immune system development GO:0002520 191 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.030
Mouse
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.030
response to organic substance GO:0010033 153 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
locomotion GO:0040011 313 0.029
Worm
cell morphogenesis GO:0000902 289 0.029
Mouse Worm
cellular amino acid metabolic process GO:0006520 7 0.029
vasculature development GO:0001944 278 0.029
alcohol biosynthetic process GO:0046165 2 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
neurotransmitter transport GO:0006836 2 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
protein import GO:0017038 3 0.028
biosynthetic process GO:0009058 294 0.028
regulation of reactive oxygen species metabolic process GO:2000377 2 0.028
protein metabolic process GO:0019538 183 0.028
Mouse
single organism metabolic process GO:0044710 217 0.028
regulation of cell activation GO:0050865 1 0.028
brain development GO:0007420 293 0.028
eye development GO:0001654 277 0.028
regulation of protein transport GO:0051223 3 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
protein secretion GO:0009306 1 0.027
developmental growth GO:0048589 166 0.027
Worm
single organism membrane fusion GO:0044801 2 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.027
ion transport GO:0006811 114 0.027
neurotransmitter secretion GO:0007269 2 0.027
blood vessel development GO:0001568 246 0.027
autophagy GO:0006914 4 0.027
Mouse
nucleic acid templated transcription GO:0097659 181 0.027
cellular biosynthetic process GO:0044249 286 0.026
monoamine transport GO:0015844 1 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.026
negative regulation of cellular process GO:0048523 283 0.026
Mouse
exocytosis GO:0006887 1 0.026
rna biosynthetic process GO:0032774 181 0.026
positive regulation of biological process GO:0048518 253 0.026
Mouse
protein targeting to nucleus GO:0044744 3 0.026
positive regulation of cytokine production GO:0001819 2 0.026
protein import into nucleus GO:0006606 3 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
neuron projection development GO:0031175 180 0.025
Mouse Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
neuron differentiation GO:0030182 353 0.025
Mouse Worm
regulation of protein targeting GO:1903533 2 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
Mouse
phosphorus metabolic process GO:0006793 109 0.025
Mouse
macromolecule biosynthetic process GO:0009059 227 0.025
cellular protein metabolic process GO:0044267 129 0.024
Mouse
regulation of wound healing GO:0061041 2 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
nuclear import GO:0051170 3 0.024
cell part morphogenesis GO:0032990 246 0.024
Mouse Worm
protein localization to nucleus GO:0034504 3 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
Mouse
tube morphogenesis GO:0035239 349 0.024
regulation of metal ion transport GO:0010959 4 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
nuclear transport GO:0051169 4 0.024
hormone transport GO:0009914 2 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
cell substrate adhesion GO:0031589 4 0.023
regulation of transcription dna templated GO:0006355 213 0.023
light absorption GO:0016037 2 0.023
cellular component morphogenesis GO:0032989 336 0.023
Mouse Worm
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.023
digestive system development GO:0055123 289 0.023
response to alkaloid GO:0043279 2 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
response to carbohydrate GO:0009743 3 0.023
muscle cell development GO:0055001 115 0.023
growth GO:0040007 174 0.023
Worm
guanosine containing compound metabolic process GO:1901068 4 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
regulation of signaling GO:0023051 235 0.023
Mouse
regulation of cell differentiation GO:0045595 142 0.022
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.022
small molecule metabolic process GO:0044281 77 0.022
muscle structure development GO:0061061 196 0.022
single organism localization GO:1902578 225 0.022
Mouse Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
Mouse
cytokinesis GO:0000910 3 0.022
amino acid transport GO:0006865 2 0.022
digestive tract development GO:0048565 265 0.022
regulation of mrna processing GO:0050684 3 0.022
response to nutrient GO:0007584 3 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.022
organic acid metabolic process GO:0006082 31 0.022
muscle cell differentiation GO:0042692 139 0.022
myeloid cell differentiation GO:0030099 86 0.022
sensory organ morphogenesis GO:0090596 200 0.022
regulation of protein catabolic process GO:0042176 1 0.022
Mouse
blood vessel morphogenesis GO:0048514 216 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
Mouse
adult behavior GO:0030534 2 0.021
regulation of developmental process GO:0050793 247 0.021
Mouse
cell motility GO:0048870 244 0.021
single organism organelle organization GO:1902589 199 0.021
response to corticosteroid GO:0031960 1 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
response to wounding GO:0009611 116 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
system process GO:0003008 185 0.021
membrane fusion GO:0061025 2 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
eye morphogenesis GO:0048592 144 0.021
skeletal system development GO:0001501 181 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
cellular component assembly GO:0022607 170 0.020
hormone secretion GO:0046879 2 0.020
cell projection morphogenesis GO:0048858 244 0.020
Mouse Worm
positive regulation of cytoskeleton organization GO:0051495 3 0.020
neuroblast proliferation GO:0007405 2 0.020
regulation of signal transduction GO:0009966 225 0.020
Mouse
regulation of synapse organization GO:0050807 3 0.020
sequestering of metal ion GO:0051238 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of muscle contraction GO:0006937 3 0.020
dicarboxylic acid transport GO:0006835 1 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
angiogenesis GO:0001525 158 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
cellular component biogenesis GO:0044085 178 0.020
embryonic organ morphogenesis GO:0048562 274 0.019
single organism nuclear import GO:1902593 3 0.019
macromolecule modification GO:0043412 111 0.019
Mouse
peptide transport GO:0015833 1 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
Mouse
compound eye development GO:0048749 2 0.019
phagocytosis engulfment GO:0006911 1 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
Mouse
regulation of binding GO:0051098 3 0.019
cellular component disassembly GO:0022411 1 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
endocrine process GO:0050886 2 0.019
positive regulation of inflammatory response GO:0050729 1 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
homeostatic process GO:0042592 142 0.019
cellular response to organic cyclic compound GO:0071407 38 0.019
wound healing GO:0042060 90 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
immune system process GO:0002376 241 0.018
regulation of dna replication GO:0006275 3 0.018
cellular response to oxygen levels GO:0071453 1 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
rna 3 end processing GO:0031123 2 0.018
regulation of glucose import GO:0046324 1 0.018
cellular response to starvation GO:0009267 1 0.018
synaptic vesicle transport GO:0048489 1 0.018
Mouse Worm
localization of cell GO:0051674 244 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
gtp catabolic process GO:0006184 2 0.018
neurological system process GO:0050877 62 0.018
defense response GO:0006952 47 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
positive regulation of immune effector process GO:0002699 3 0.018
lipid homeostasis GO:0055088 3 0.017
rna localization GO:0006403 4 0.017
response to vitamin GO:0033273 3 0.017
response to external stimulus GO:0009605 264 0.017
Worm
erk1 and erk2 cascade GO:0070371 4 0.017
transmembrane transport GO:0055085 120 0.017
macromolecular complex disassembly GO:0032984 1 0.017
carbohydrate homeostasis GO:0033500 1 0.017
oxoacid metabolic process GO:0043436 31 0.017
negative regulation of signaling GO:0023057 96 0.017
glucose homeostasis GO:0042593 1 0.017
regulation of postsynaptic membrane potential GO:0060078 1 0.017
Mouse
regulation of calcium ion transport GO:0051924 2 0.017
protein complex localization GO:0031503 1 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
cellular response to organic substance GO:0071310 105 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
Mouse Worm
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.017
mitochondrion organization GO:0007005 4 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
Mouse Worm
response to monosaccharide GO:0034284 3 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
phototransduction GO:0007602 2 0.016
cellular response to radiation GO:0071478 4 0.016
membrane invagination GO:0010324 1 0.016
endosomal transport GO:0016197 2 0.016
regulation of blood vessel size GO:0050880 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
sequestering of calcium ion GO:0051208 3 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of gene expression GO:0010468 265 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
protein polymerization GO:0051258 4 0.016
cell matrix adhesion GO:0007160 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
cell projection organization GO:0030030 284 0.016
Mouse Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
regulation of endocrine process GO:0044060 2 0.016
protein modification process GO:0036211 100 0.016
Mouse
interspecies interaction between organisms GO:0044419 4 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
Mouse
b cell activation GO:0042113 2 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of reproductive process GO:2000241 4 0.015
digestive tract morphogenesis GO:0048546 231 0.015
gastrulation GO:0007369 208 0.015
regulation of myotube differentiation GO:0010830 2 0.015
antimicrobial humoral response GO:0019730 2 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
Mouse
regulation of cell shape GO:0008360 1 0.015
tissue remodeling GO:0048771 4 0.015
regulation of hormone secretion GO:0046883 2 0.015
negative regulation of cytokine production GO:0001818 1 0.015
behavior GO:0007610 74 0.015
Mouse
chemosensory behavior GO:0007635 1 0.015
cell death GO:0008219 121 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
peptidyl serine modification GO:0018209 2 0.015
response to hexose GO:0009746 3 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
Mouse Worm
stem cell maintenance GO:0019827 4 0.015
gtp metabolic process GO:0046039 4 0.015
actin filament based movement GO:0030048 1 0.015
fat soluble vitamin metabolic process GO:0006775 4 0.015
regulation of sequestering of calcium ion GO:0051282 4 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
regulation of blood pressure GO:0008217 1 0.015
protein localization to plasma membrane GO:0072659 1 0.015
protein complex disassembly GO:0043241 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
actin filament polymerization GO:0030041 2 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
sensory perception of pain GO:0019233 1 0.014
regulation of glucose transport GO:0010827 1 0.014
regulation of protein polymerization GO:0032271 2 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
regulation of apoptotic process GO:0042981 98 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
cellular component maintenance GO:0043954 3 0.014
response to glucose GO:0009749 3 0.014
regulation of biosynthetic process GO:0009889 250 0.014
regulation of dendrite development GO:0050773 3 0.014
Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.014
fertilization GO:0009566 3 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
regulation of inflammatory response GO:0050727 2 0.014
cation transport GO:0006812 81 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
notochord development GO:0030903 54 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
negative regulation of secretion GO:0051048 2 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
heart development GO:0007507 313 0.014
rna processing GO:0006396 25 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
skeletal system morphogenesis GO:0048705 102 0.014
atp catabolic process GO:0006200 4 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
monocyte differentiation GO:0030224 2 0.013
cell migration GO:0016477 237 0.013
phototransduction visible light GO:0007603 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
response to glucocorticoid GO:0051384 1 0.013
cell proliferation GO:0008283 80 0.013
regulation of programmed cell death GO:0043067 101 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
microtubule organizing center organization GO:0031023 1 0.013
lymphocyte proliferation GO:0046651 1 0.013
small molecule catabolic process GO:0044282 3 0.013
secondary metabolic process GO:0019748 3 0.013
b cell mediated immunity GO:0019724 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
response to lipid GO:0033993 60 0.013
post embryonic morphogenesis GO:0009886 4 0.013
centrosome organization GO:0051297 1 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
rna catabolic process GO:0006401 7 0.013
camera type eye morphogenesis GO:0048593 108 0.013
death GO:0016265 121 0.013
membrane hyperpolarization GO:0060081 1 0.013
reactive oxygen species metabolic process GO:0072593 6 0.013
muscle tissue development GO:0060537 110 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
positive regulation of translation GO:0045727 1 0.013
protein dephosphorylation GO:0006470 3 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
positive regulation of wound healing GO:0090303 1 0.013
regulation of tube size GO:0035150 2 0.013
anion transport GO:0006820 38 0.013
striated muscle cell differentiation GO:0051146 129 0.013
response to abiotic stimulus GO:0009628 122 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of organ growth GO:0046620 3 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
somite development GO:0061053 96 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
camera type eye development GO:0043010 222 0.012
axonogenesis GO:0007409 152 0.012
Worm
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
establishment of localization in cell GO:0051649 77 0.012
Mouse Worm
spermatid development GO:0007286 2 0.012
glucose import GO:0046323 2 0.012
retina development in camera type eye GO:0060041 146 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
protein acylation GO:0043543 3 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
adherens junction organization GO:0034332 4 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
protein polyubiquitination GO:0000209 4 0.012
regeneration GO:0031099 91 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
transmission of nerve impulse GO:0019226 19 0.012
protein heterooligomerization GO:0051291 1 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
muscle organ development GO:0007517 101 0.012
centrosome duplication GO:0051298 1 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
meiotic nuclear division GO:0007126 4 0.012
axon development GO:0061564 166 0.012
Worm
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
striated muscle tissue development GO:0014706 110 0.012
blood circulation GO:0008015 87 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
ion transmembrane transport GO:0034220 91 0.012
positive regulation of cellular process GO:0048522 201 0.012
Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
embryonic skeletal system development GO:0048706 97 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
urogenital system development GO:0001655 97 0.011
Mouse
regulation of receptor activity GO:0010469 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of autophagy GO:0010506 3 0.011
Mouse
programmed cell death GO:0012501 119 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
Mouse
regulation of gene expression epigenetic GO:0040029 11 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
determination of left right symmetry GO:0007368 179 0.011
positive regulation of cell substrate adhesion GO:0010811 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
somitogenesis GO:0001756 87 0.011
regulation of synapse assembly GO:0051963 3 0.011
golgi vesicle transport GO:0048193 3 0.011
establishment of vesicle localization GO:0051650 24 0.011
Mouse Worm
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
intracellular signal transduction GO:0035556 85 0.011
Mouse
endocrine hormone secretion GO:0060986 2 0.011
striated muscle cell development GO:0055002 108 0.011
heart looping GO:0001947 94 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of protein binding GO:0043393 3 0.011
negative regulation of dna replication GO:0008156 2 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
response to hormone GO:0009725 48 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
sprouting angiogenesis GO:0002040 53 0.011
negative regulation of protein transport GO:0051224 3 0.011
cation transmembrane transport GO:0098655 65 0.011
stem cell division GO:0017145 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
nitric oxide metabolic process GO:0046209 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
Mouse
multicellular organismal metabolic process GO:0044236 2 0.011
adherens junction maintenance GO:0034334 2 0.011
response to inorganic substance GO:0010035 38 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of mrna catabolic process GO:0061013 3 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
Mouse

lrrk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.065
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
cardiovascular system disease DOID:1287 0 0.013
inherited metabolic disorder DOID:655 0 0.011