Danio rerio

7 known processes

LOC100002342

carboxypeptidase A6-like

LOC100002342 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle biosynthetic process GO:0018130 215 0.461
heart development GO:0007507 313 0.454
regulation of nitrogen compound metabolic process GO:0051171 251 0.451
embryonic organ morphogenesis GO:0048562 274 0.389
chordate embryonic development GO:0043009 271 0.369
regulation of cellular metabolic process GO:0031323 320 0.340
embryonic limb morphogenesis GO:0030326 2 0.283
sensory organ morphogenesis GO:0090596 200 0.280
regulation of primary metabolic process GO:0080090 311 0.279
sensory organ development GO:0007423 393 0.255
monoamine transport GO:0015844 1 0.237
generation of neurons GO:0048699 385 0.229
cellular biosynthetic process GO:0044249 286 0.224
eye morphogenesis GO:0048592 144 0.216
skeletal system development GO:0001501 181 0.201
embryonic organ development GO:0048568 381 0.198
embryonic cranial skeleton morphogenesis GO:0048701 90 0.196
regulation of cell communication GO:0010646 232 0.186
regulation of biological quality GO:0065008 263 0.183
macromolecule biosynthetic process GO:0009059 227 0.170
regulation of metabolic process GO:0019222 359 0.162
regulation of macromolecule metabolic process GO:0060255 317 0.161
camera type eye morphogenesis GO:0048593 108 0.148
cellular macromolecule biosynthetic process GO:0034645 224 0.148
eye development GO:0001654 277 0.143
regulation of rna metabolic process GO:0051252 224 0.140
cell part morphogenesis GO:0032990 246 0.137
positive regulation of biological process GO:0048518 253 0.125
cellular macromolecule metabolic process GO:0044260 391 0.124
ear development GO:0043583 127 0.120
neuron differentiation GO:0030182 353 0.120
axonogenesis GO:0007409 152 0.117
retina development in camera type eye GO:0060041 146 0.115
cellular aromatic compound metabolic process GO:0006725 295 0.114
skeletal muscle tissue development GO:0007519 67 0.106
heterocycle metabolic process GO:0046483 290 0.105
camera type eye development GO:0043010 222 0.101
regulation of signaling GO:0023051 235 0.100
regulation of gene expression GO:0010468 265 0.100
signal transduction GO:0007165 455 0.099
neuron projection guidance GO:0097485 86 0.099
cellular component movement GO:0006928 335 0.098
embryo development ending in birth or egg hatching GO:0009792 271 0.094
gland development GO:0048732 143 0.094
cellular component morphogenesis GO:0032989 336 0.092
mesenchyme development GO:0060485 127 0.092
head development GO:0060322 303 0.091
regulation of cellular biosynthetic process GO:0031326 245 0.091
striated muscle tissue development GO:0014706 110 0.086
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.085
nitrogen compound metabolic process GO:0006807 319 0.084
cellular nitrogen compound metabolic process GO:0034641 290 0.084
immune system process GO:0002376 241 0.083
regulation of biosynthetic process GO:0009889 250 0.081
regulation of binding GO:0051098 3 0.081
organic substance biosynthetic process GO:1901576 289 0.080
blood vessel development GO:0001568 246 0.078
skeletal system morphogenesis GO:0048705 102 0.078
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.075
regulation of multicellular organismal development GO:2000026 223 0.075
regulation of response to stimulus GO:0048583 269 0.074
cellular nitrogen compound biosynthetic process GO:0044271 218 0.073
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.073
localization of cell GO:0051674 244 0.072
regulation of system process GO:0044057 40 0.072
negative regulation of cellular process GO:0048523 283 0.072
nucleobase containing compound metabolic process GO:0006139 274 0.071
positive regulation of cellular process GO:0048522 201 0.069
blood vessel morphogenesis GO:0048514 216 0.068
embryonic skeletal system development GO:0048706 97 0.068
nucleic acid templated transcription GO:0097659 181 0.067
regulation of signal transduction GO:0009966 225 0.067
biosynthetic process GO:0009058 294 0.067
positive regulation of gene expression GO:0010628 71 0.067
embryonic skeletal system morphogenesis GO:0048704 93 0.066
regulation of rna biosynthetic process GO:2001141 213 0.064
rna metabolic process GO:0016070 219 0.059
organic cyclic compound biosynthetic process GO:1901362 223 0.059
muscle cell differentiation GO:0042692 139 0.059
programmed cell death GO:0012501 119 0.057
positive regulation of cellular component biogenesis GO:0044089 3 0.056
transcription dna templated GO:0006351 181 0.056
gene expression GO:0010467 252 0.055
cell morphogenesis involved in differentiation GO:0000904 195 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.054
axon development GO:0061564 166 0.054
appendage development GO:0048736 80 0.053
forebrain development GO:0030900 96 0.051
synaptic transmission glycinergic GO:0060012 1 0.051
determination of bilateral symmetry GO:0009855 204 0.050
cell projection organization GO:0030030 284 0.050
determination of left right symmetry GO:0007368 179 0.049
response to stress GO:0006950 263 0.049
organic acid metabolic process GO:0006082 31 0.048
biomineral tissue development GO:0031214 13 0.047
digestive system development GO:0055123 289 0.047
aging GO:0007568 2 0.046
brain development GO:0007420 293 0.046
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.046
system process GO:0003008 185 0.045
regulation of multicellular organismal process GO:0051239 277 0.044
somatic muscle development GO:0007525 4 0.044
response to chemical GO:0042221 320 0.044
rna biosynthetic process GO:0032774 181 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
inner ear development GO:0048839 126 0.043
regulation of apoptotic process GO:0042981 98 0.042
nucleic acid metabolic process GO:0090304 244 0.042
regulation of wound healing GO:0061041 2 0.042
larval development GO:0002164 2 0.042
central nervous system development GO:0007417 387 0.042
regulation of transcription dna templated GO:0006355 213 0.042
vasculature development GO:0001944 278 0.041
positive regulation of metabolic process GO:0009893 108 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
organic cyclic compound metabolic process GO:1901360 301 0.040
muscle structure development GO:0061061 196 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.040
response to vitamin GO:0033273 3 0.040
liver development GO:0001889 96 0.039
angiogenesis GO:0001525 158 0.039
negative regulation of biological process GO:0048519 304 0.038
sprouting angiogenesis GO:0002040 53 0.038
intracellular receptor signaling pathway GO:0030522 30 0.038
neuron projection development GO:0031175 180 0.038
cell morphogenesis GO:0000902 289 0.037
specification of symmetry GO:0009799 204 0.037
digestive tract development GO:0048565 265 0.036
morphogenesis of an epithelium GO:0002009 333 0.036
embryonic neurocranium morphogenesis GO:0048702 15 0.035
meiotic chromosome segregation GO:0045132 3 0.035
bmp signaling pathway GO:0030509 52 0.034
cell proliferation GO:0008283 80 0.034
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.034
regulation of cell death GO:0010941 103 0.034
death GO:0016265 121 0.034
regulation of developmental process GO:0050793 247 0.034
locomotion GO:0040011 313 0.034
determination of heart left right asymmetry GO:0061371 117 0.034
muscle organ development GO:0007517 101 0.034
neuron development GO:0048666 262 0.033
skeletal muscle organ development GO:0060538 78 0.033
positive regulation of rna metabolic process GO:0051254 59 0.033
odontogenesis of dentin containing tooth GO:0042475 1 0.033
taxis GO:0042330 109 0.033
heart morphogenesis GO:0003007 156 0.032
mesoderm development GO:0007498 88 0.032
axon guidance GO:0007411 86 0.031
enzyme linked receptor protein signaling pathway GO:0007167 106 0.031
extrinsic apoptotic signaling pathway GO:0097191 3 0.031
neuron projection regeneration GO:0031102 16 0.031
phosphate containing compound metabolic process GO:0006796 108 0.030
adult behavior GO:0030534 2 0.030
neurotransmitter transport GO:0006836 2 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
hepaticobiliary system development GO:0061008 98 0.030
transcription from rna polymerase ii promoter GO:0006366 80 0.030
heart process GO:0003015 71 0.029
blood coagulation GO:0007596 12 0.029
retinoic acid receptor signaling pathway GO:0048384 16 0.029
regulation of programmed cell death GO:0043067 101 0.029
retina morphogenesis in camera type eye GO:0060042 79 0.028
meiotic cell cycle process GO:1903046 3 0.028
muscle tissue development GO:0060537 110 0.027
positive regulation of rna biosynthetic process GO:1902680 57 0.027
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 1 0.026
ear morphogenesis GO:0042471 64 0.025
behavior GO:0007610 74 0.025
negative regulation of response to stimulus GO:0048585 104 0.024
phagocytosis engulfment GO:0006911 1 0.024
immune system development GO:0002520 191 0.024
central nervous system neuron differentiation GO:0021953 74 0.024
apoptotic process GO:0006915 116 0.024
regulation of protein binding GO:0043393 3 0.023
tube morphogenesis GO:0035239 349 0.023
endothelial cell fate commitment GO:0060839 3 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
mitochondrion organization GO:0007005 4 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
regulation of response to external stimulus GO:0032101 31 0.023
nephron tubule morphogenesis GO:0072078 1 0.023
regulation of protein catabolic process GO:0042176 1 0.023
cell projection morphogenesis GO:0048858 244 0.023
inner ear morphogenesis GO:0042472 63 0.022
venous blood vessel morphogenesis GO:0048845 3 0.022
regulation of vasculature development GO:1901342 33 0.022
phagocytosis GO:0006909 3 0.022
negative regulation of chemotaxis GO:0050922 4 0.022
stem cell proliferation GO:0072089 4 0.022
regulation of reproductive process GO:2000241 4 0.022
cell motility GO:0048870 244 0.022
vasculogenesis GO:0001570 41 0.022
positive regulation of cell death GO:0010942 29 0.021
membrane invagination GO:0010324 1 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
positive regulation of cell adhesion GO:0045785 1 0.021
negative regulation of metabolic process GO:0009892 86 0.021
neurotransmitter secretion GO:0007269 2 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
appendage morphogenesis GO:0035107 56 0.020
muscle cell development GO:0055001 115 0.020
lymph vessel development GO:0001945 27 0.020
regulation of bmp signaling pathway GO:0030510 39 0.020
morphogenesis of an epithelial fold GO:0060571 1 0.020
female sex differentiation GO:0046660 4 0.019
response to hydrogen peroxide GO:0042542 3 0.019
negative regulation of signaling GO:0023057 96 0.019
mesenchymal cell development GO:0014031 78 0.019
regulation of neurogenesis GO:0050767 87 0.019
transport GO:0006810 220 0.019
embryonic appendage morphogenesis GO:0035113 30 0.019
regulation of dendrite development GO:0050773 3 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
positive regulation of cell cycle GO:0045787 3 0.018
positive regulation of axon guidance GO:1902669 1 0.018
negative regulation of cell communication GO:0010648 96 0.018
cellular aldehyde metabolic process GO:0006081 4 0.018
negative regulation of axon guidance GO:1902668 1 0.018
negative regulation of cell development GO:0010721 26 0.018
phosphorylation GO:0016310 69 0.018
regulation of cell proliferation GO:0042127 37 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
central nervous system neuron development GO:0021954 29 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
carboxylic acid biosynthetic process GO:0046394 12 0.018
cellular protein modification process GO:0006464 100 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
protein import GO:0017038 3 0.018
lymphangiogenesis GO:0001946 25 0.018
myeloid cell differentiation GO:0030099 86 0.017
pronephros development GO:0048793 69 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
connective tissue development GO:0061448 99 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
wound healing GO:0042060 90 0.017
mechanosensory lateral line system development GO:0048881 49 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
circulatory system process GO:0003013 87 0.017
negative regulation of gene expression GO:0010629 65 0.017
developmental cell growth GO:0048588 52 0.017
response to inorganic substance GO:0010035 38 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
diterpenoid biosynthetic process GO:0016102 7 0.017
homeostatic process GO:0042592 142 0.017
meiotic nuclear division GO:0007126 4 0.017
regulation of oxidative stress induced cell death GO:1903201 2 0.016
limb morphogenesis GO:0035108 7 0.016
regulation of blood circulation GO:1903522 32 0.016
retina vasculature development in camera type eye GO:0061298 2 0.016
positive regulation of transport GO:0051050 2 0.016
regulation of membrane potential GO:0042391 23 0.016
single organism metabolic process GO:0044710 217 0.016
amine metabolic process GO:0009308 2 0.016
hypothalamus cell differentiation GO:0021979 4 0.016
cell cell signaling GO:0007267 52 0.016
diencephalon development GO:0021536 58 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
regulation of cell differentiation GO:0045595 142 0.016
multicellular organism growth GO:0035264 4 0.015
protein localization to nucleus GO:0034504 3 0.015
regulation of neurological system process GO:0031644 2 0.015
single organism biosynthetic process GO:0044711 71 0.015
tissue remodeling GO:0048771 4 0.015
regulation of bone mineralization GO:0030500 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
response to nutrient GO:0007584 3 0.015
regulation of myotube differentiation GO:0010830 2 0.015
protein metabolic process GO:0019538 183 0.015
striated muscle cell differentiation GO:0051146 129 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
urogenital system development GO:0001655 97 0.015
neuron projection morphogenesis GO:0048812 161 0.015
striated muscle cell development GO:0055002 108 0.014
mitotic recombination GO:0006312 2 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
positive regulation of muscle organ development GO:0048636 1 0.014
water homeostasis GO:0030104 4 0.014
regeneration GO:0031099 91 0.014
embryonic camera type eye morphogenesis GO:0048596 19 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
regulation of axon guidance GO:1902667 8 0.014
macromolecule modification GO:0043412 111 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
epithelial cell differentiation GO:0030855 116 0.014
organic hydroxy compound transport GO:0015850 14 0.014
regulation of biomineral tissue development GO:0070167 2 0.014
developmental programmed cell death GO:0010623 4 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
mitotic g2 m transition checkpoint GO:0044818 3 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
dna catabolic process GO:0006308 1 0.014
double strand break repair GO:0006302 3 0.014
branchiomotor neuron axon guidance GO:0021785 1 0.014
exocrine system development GO:0035272 28 0.014
intracellular signal transduction GO:0035556 85 0.013
lymph vessel morphogenesis GO:0036303 25 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
cellular response to stress GO:0033554 62 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
nuclear transport GO:0051169 4 0.013
small molecule catabolic process GO:0044282 3 0.013
coagulation GO:0050817 13 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
hindbrain development GO:0030902 91 0.013
diterpenoid metabolic process GO:0016101 15 0.013
glial cell migration GO:0008347 3 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
embryonic eye morphogenesis GO:0048048 30 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
response to endogenous stimulus GO:0009719 83 0.013
astrocyte differentiation GO:0048708 1 0.013
hemostasis GO:0007599 13 0.013
response to external stimulus GO:0009605 264 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
neural crest cell migration GO:0001755 42 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
cellular amine metabolic process GO:0044106 2 0.013
apoptotic signaling pathway GO:0097190 23 0.013
hindbrain morphogenesis GO:0021575 22 0.013
neural tube patterning GO:0021532 33 0.013
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of blood vessel size GO:0050880 2 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
fin development GO:0033333 77 0.012
embryonic pattern specification GO:0009880 44 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
regulation of transporter activity GO:0032409 2 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
growth GO:0040007 174 0.012
oxoacid metabolic process GO:0043436 31 0.012
determination of digestive tract left right asymmetry GO:0071907 10 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
limb development GO:0060173 8 0.012
regulation of response to stress GO:0080134 36 0.012
organelle organization GO:0006996 227 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
negative regulation of reproductive process GO:2000242 3 0.012
regulation of filopodium assembly GO:0051489 2 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
limbic system development GO:0021761 16 0.012
nuclear import GO:0051170 3 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
post embryonic organ development GO:0048569 4 0.012
regionalization GO:0003002 274 0.012
cellular response to reactive oxygen species GO:0034614 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
negative regulation of cell death GO:0060548 60 0.011
regulation of extent of cell growth GO:0061387 29 0.011
forebrain neuron differentiation GO:0021879 14 0.011
cartilage development GO:0051216 96 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
positive regulation of secretion GO:0051047 1 0.011
lens fiber cell development GO:0070307 3 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
response to drug GO:0042493 3 0.011
female gonad development GO:0008585 4 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
neuron projection extension GO:1990138 45 0.011
negative regulation of signal transduction GO:0009968 94 0.011
single organism transport GO:0044765 206 0.011
establishment of blood brain barrier GO:0060856 2 0.011
muscle fiber development GO:0048747 52 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
regulation of cellular response to growth factor stimulus GO:0090287 35 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
pharyngeal system development GO:0060037 18 0.011
stem cell differentiation GO:0048863 117 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
primitive erythrocyte differentiation GO:0060319 5 0.011
gastrulation GO:0007369 208 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
regulation of muscle hypertrophy GO:0014743 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
response to growth factor GO:0070848 39 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
cell migration GO:0016477 237 0.010
telomere maintenance GO:0000723 1 0.010
apoptotic process involved in development GO:1902742 2 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
lens fiber cell morphogenesis GO:0070309 3 0.010
response to uv GO:0009411 3 0.010
heart contraction GO:0060047 71 0.010
regulation of tube size GO:0035150 2 0.010
formation of primary germ layer GO:0001704 62 0.010
tube closure GO:0060606 1 0.010
bone remodeling GO:0046849 2 0.010
regulation of cell fate commitment GO:0010453 22 0.010
semicircular canal development GO:0060872 24 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
regulation of protein transport GO:0051223 3 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
retinal metabolic process GO:0042574 3 0.010
telomere organization GO:0032200 1 0.010

LOC100002342 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
musculoskeletal system disease DOID:17 0 0.024
immune system disease DOID:2914 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011