Danio rerio

0 known processes

myl1

myosin, light chain 1, alkali; skeletal, fast

(Aliases: zgc:65785,zgc:77231,fj53a11,wu:fj53a11)

myl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actomyosin structure organization GO:0031032 53 0.973
Zebrafish
striated muscle cell development GO:0055002 108 0.969
Zebrafish
actin filament based process GO:0030029 64 0.909
Zebrafish Fly
cardiac muscle cell differentiation GO:0055007 30 0.786
Zebrafish
ventricular cardiac myofibril assembly GO:0055005 4 0.773
Zebrafish
heart morphogenesis GO:0003007 156 0.771
Zebrafish
heart contraction GO:0060047 71 0.759
Zebrafish Rat
muscle cell development GO:0055001 115 0.718
Zebrafish
muscle cell differentiation GO:0042692 139 0.690
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.687
Zebrafish
heart development GO:0007507 313 0.671
Zebrafish
sarcomere organization GO:0045214 26 0.628
Zebrafish
myofibril assembly GO:0030239 48 0.607
Zebrafish
single organism organelle organization GO:1902589 199 0.579
Zebrafish
muscle system process GO:0003012 20 0.554
Rat
cytokinesis GO:0000910 3 0.502
Worm
cardiac muscle cell development GO:0055013 20 0.490
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.485
Zebrafish
ventricular cardiac muscle cell differentiation GO:0055012 6 0.475
Zebrafish
skeletal muscle thin filament assembly GO:0030240 4 0.468
regulation of muscle contraction GO:0006937 3 0.468
cellular component biogenesis GO:0044085 178 0.467
Zebrafish
cellular component assembly GO:0022607 170 0.456
Zebrafish
circulatory system process GO:0003013 87 0.398
Zebrafish Rat
cellular component morphogenesis GO:0032989 336 0.394
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.371
Zebrafish
larval development GO:0002164 2 0.352
cardiac myofibril assembly GO:0055003 9 0.341
Zebrafish
striated muscle contraction GO:0006941 12 0.333
Rat
muscle contraction GO:0006936 18 0.309
Rat
organelle organization GO:0006996 227 0.302
Zebrafish
organelle assembly GO:0070925 110 0.290
Zebrafish
actin cytoskeleton organization GO:0030036 63 0.281
Zebrafish
heart process GO:0003015 71 0.281
Zebrafish Rat
nitrogen compound metabolic process GO:0006807 319 0.271
lymphoid lineage cell migration GO:0097534 4 0.271
blood circulation GO:0008015 87 0.270
Zebrafish Rat
cardiac cell development GO:0055006 21 0.270
Zebrafish
regulation of nitric oxide mediated signal transduction GO:0010749 1 0.243
lymphoid lineage cell migration into thymus GO:0097535 4 0.236
muscle structure development GO:0061061 196 0.231
Zebrafish
purine nucleoside monophosphate catabolic process GO:0009128 4 0.212
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.197
rna biosynthetic process GO:0032774 181 0.189
skeletal myofibril assembly GO:0014866 7 0.188
endocardial cushion formation GO:0003272 2 0.186
aromatic compound biosynthetic process GO:0019438 217 0.182
oocyte anterior posterior axis specification GO:0007314 4 0.164
maintenance of location GO:0051235 4 0.162
regulation of heart contraction GO:0008016 32 0.161
protein polymerization GO:0051258 4 0.157
striated muscle tissue development GO:0014706 110 0.152
Zebrafish
chordate embryonic development GO:0043009 271 0.152
cytoskeleton organization GO:0007010 96 0.145
Zebrafish
reactive nitrogen species metabolic process GO:2001057 0 0.145
cardiocyte differentiation GO:0035051 44 0.143
Zebrafish
cell projection organization GO:0030030 284 0.130
positive regulation of blood circulation GO:1903524 2 0.130
neuron development GO:0048666 262 0.127
regulation of nucleoside metabolic process GO:0009118 2 0.116
organic substance biosynthetic process GO:1901576 289 0.115
regulation of protein complex assembly GO:0043254 3 0.115
somitogenesis GO:0001756 87 0.112
neuron projection development GO:0031175 180 0.112
regulation of nitrogen compound metabolic process GO:0051171 251 0.110
cellular biosynthetic process GO:0044249 286 0.106
positive regulation of biological process GO:0048518 253 0.105
ribonucleoside monophosphate catabolic process GO:0009158 4 0.104
atrial cardiac myofibril assembly GO:0055004 2 0.101
regulation of biological quality GO:0065008 263 0.097
small molecule metabolic process GO:0044281 77 0.094
atp catabolic process GO:0006200 4 0.087
nucleoside monophosphate catabolic process GO:0009125 4 0.085
reproduction GO:0000003 40 0.084
muscle tissue development GO:0060537 110 0.084
Zebrafish
locomotion GO:0040011 313 0.081
cellular amino acid biosynthetic process GO:0008652 2 0.079
regulation of cell death GO:0010941 103 0.078
embryonic organ development GO:0048568 381 0.078
mitochondrion organization GO:0007005 4 0.077
skeletal muscle organ development GO:0060538 78 0.076
system process GO:0003008 185 0.074
Zebrafish Rat
organic cyclic compound metabolic process GO:1901360 301 0.074
endocardial cushion morphogenesis GO:0003203 3 0.074
cellular aromatic compound metabolic process GO:0006725 295 0.072
regulation of protein polymerization GO:0032271 2 0.070
protein complex assembly GO:0006461 30 0.070
cellular calcium ion homeostasis GO:0006874 13 0.069
multi organism process GO:0051704 134 0.069
segmentation GO:0035282 97 0.068
regulation of reproductive process GO:2000241 4 0.068
cellular nitrogen compound biosynthetic process GO:0044271 218 0.067
regulation of purine nucleotide catabolic process GO:0033121 2 0.066
lipid storage GO:0019915 1 0.065
cellular nitrogen compound metabolic process GO:0034641 290 0.063
regulation of cell communication GO:0010646 232 0.062
cardiac muscle tissue morphogenesis GO:0055008 7 0.060
regulation of metabolic process GO:0019222 359 0.060
embryo development ending in birth or egg hatching GO:0009792 271 0.059
Worm
carbohydrate derivative metabolic process GO:1901135 61 0.058
regulation of cellular biosynthetic process GO:0031326 245 0.058
regulation of cellular metabolic process GO:0031323 320 0.057
organonitrogen compound metabolic process GO:1901564 74 0.056
oxoacid metabolic process GO:0043436 31 0.056
neuron differentiation GO:0030182 353 0.055
regulation of multicellular organismal process GO:0051239 277 0.055
ventricular cardiac muscle tissue development GO:0003229 3 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.053
sequestering of calcium ion GO:0051208 3 0.053
aging GO:0007568 2 0.052
biosynthetic process GO:0009058 294 0.051
cellular component maintenance GO:0043954 3 0.049
mitotic cytokinesis GO:0000281 3 0.048
Worm
embryonic heart tube development GO:0035050 133 0.047
organic acid metabolic process GO:0006082 31 0.047
macromolecular complex subunit organization GO:0043933 74 0.046
regulation of nucleotide catabolic process GO:0030811 2 0.046
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
regulation of system process GO:0044057 40 0.043
regulation of cell projection assembly GO:0060491 4 0.042
regulation of sequestering of calcium ion GO:0051282 4 0.041
negative regulation of protein kinase activity GO:0006469 4 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.040
positive regulation of heart contraction GO:0045823 2 0.040
single organism biosynthetic process GO:0044711 71 0.039
pigmentation GO:0043473 85 0.039
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.039
cardiac muscle contraction GO:0060048 6 0.039
Rat
multicellular organismal reproductive process GO:0048609 35 0.039
stem cell differentiation GO:0048863 117 0.038
cellular modified amino acid metabolic process GO:0006575 3 0.038
skeletal muscle myosin thick filament assembly GO:0030241 5 0.036
reproductive process GO:0022414 40 0.036
mesenchyme development GO:0060485 127 0.035
carboxylic acid metabolic process GO:0019752 22 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.035
heart looping GO:0001947 94 0.034
cytoskeleton dependent cytokinesis GO:0061640 3 0.034
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.033
regulation of behavior GO:0050795 24 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.033
regulation of cell shape GO:0008360 1 0.033
nitric oxide metabolic process GO:0046209 2 0.032
cellular lipid catabolic process GO:0044242 3 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
actin filament organization GO:0007015 15 0.032
cellular macromolecular complex assembly GO:0034622 24 0.032
transcription dna templated GO:0006351 181 0.032
regulation of cytoskeleton organization GO:0051493 11 0.031
twitch skeletal muscle contraction GO:0014721 4 0.031
rna localization GO:0006403 4 0.031
regulation of blood circulation GO:1903522 32 0.031
cell part morphogenesis GO:0032990 246 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
cell substrate adhesion GO:0031589 4 0.030
cell division GO:0051301 20 0.030
Worm
protein complex subunit organization GO:0071822 46 0.030
gene expression GO:0010467 252 0.030
heterocycle metabolic process GO:0046483 290 0.029
negative regulation of kinase activity GO:0033673 4 0.029
positive regulation of rna biosynthetic process GO:1902680 57 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
positive regulation of transport GO:0051050 2 0.029
purine ribonucleoside biosynthetic process GO:0046129 2 0.029
cell projection morphogenesis GO:0048858 244 0.029
intestinal absorption GO:0050892 2 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
cytoplasm organization GO:0007028 4 0.028
mitotic cell cycle process GO:1903047 48 0.028
Worm
reactive oxygen species metabolic process GO:0072593 6 0.028
venous blood vessel morphogenesis GO:0048845 3 0.028
cardiac chamber development GO:0003205 19 0.028
regulation of tube size GO:0035150 2 0.028
blood vessel development GO:0001568 246 0.028
pole plasm assembly GO:0007315 4 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
lipid homeostasis GO:0055088 3 0.027
homeostatic process GO:0042592 142 0.027
angiogenesis GO:0001525 158 0.027
muscle organ morphogenesis GO:0048644 8 0.027
rna metabolic process GO:0016070 219 0.027
regulation of protein binding GO:0043393 3 0.027
maternal determination of anterior posterior axis embryo GO:0008358 4 0.027
neuromuscular synaptic transmission GO:0007274 2 0.026
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.026
nitric oxide biosynthetic process GO:0006809 2 0.026
somite development GO:0061053 96 0.026
purine containing compound metabolic process GO:0072521 29 0.026
regulation of response to stress GO:0080134 36 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
single organism metabolic process GO:0044710 217 0.026
multi organism reproductive process GO:0044703 36 0.026
regulation of ion transmembrane transporter activity GO:0032412 2 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
cellular protein modification process GO:0006464 100 0.025
macromolecular complex assembly GO:0065003 35 0.025
mesenchyme morphogenesis GO:0072132 5 0.025
organophosphate biosynthetic process GO:0090407 23 0.025
positive regulation of transcription dna templated GO:0045893 57 0.025
regulation of binding GO:0051098 3 0.024
protein metabolic process GO:0019538 183 0.024
cell cycle process GO:0022402 53 0.024
Worm
cardiac ventricle development GO:0003231 9 0.024
regulation of signal transduction GO:0009966 225 0.024
anatomical structure homeostasis GO:0060249 36 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
meiotic nuclear division GO:0007126 4 0.024
protein stabilization GO:0050821 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
lipid digestion GO:0044241 3 0.023
anterior posterior pattern specification GO:0009952 152 0.023
kidney development GO:0001822 92 0.023
positive regulation of nucleoside metabolic process GO:0045979 1 0.023
macromolecular complex disassembly GO:0032984 1 0.023
organic acid catabolic process GO:0016054 3 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
cellular protein complex assembly GO:0043623 19 0.022
er nucleus signaling pathway GO:0006984 2 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.022
lamellipodium organization GO:0097581 1 0.022
adult behavior GO:0030534 2 0.022
tube morphogenesis GO:0035239 349 0.022
cardiac chamber morphogenesis GO:0003206 12 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
post embryonic morphogenesis GO:0009886 4 0.021
death GO:0016265 121 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
regulation of protein complex disassembly GO:0043244 1 0.021
dopamine biosynthetic process GO:0042416 2 0.021
cellular component disassembly GO:0022411 1 0.021
nucleoside triphosphate biosynthetic process GO:0009142 2 0.021
regulation of response to stimulus GO:0048583 269 0.021
determination of bilateral symmetry GO:0009855 204 0.020
ventricular cardiac muscle cell development GO:0055015 5 0.020
Zebrafish
syncytium formation by plasma membrane fusion GO:0000768 12 0.020
regionalization GO:0003002 274 0.020
generation of neurons GO:0048699 385 0.020
nucleic acid metabolic process GO:0090304 244 0.019
mesoderm development GO:0007498 88 0.019
regulation of metal ion transport GO:0010959 4 0.019
neuron projection morphogenesis GO:0048812 161 0.019
apoptotic process GO:0006915 116 0.019
regulation of response to cytokine stimulus GO:0060759 3 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
regulation of protein depolymerization GO:1901879 1 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
purine nucleotide metabolic process GO:0006163 27 0.019
muscle fiber development GO:0048747 52 0.019
somatic muscle development GO:0007525 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.018
negative regulation of biological process GO:0048519 304 0.018
nucleoside biosynthetic process GO:0009163 2 0.018
cellular localization GO:0051641 97 0.018
phosphorus metabolic process GO:0006793 109 0.018
oogenesis GO:0048477 14 0.018
eye development GO:0001654 277 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
ribose phosphate metabolic process GO:0019693 27 0.018
purine ribonucleotide metabolic process GO:0009150 27 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
actin filament polymerization GO:0030041 2 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
axon development GO:0061564 166 0.017
intracellular signal transduction GO:0035556 85 0.017
p38mapk cascade GO:0038066 1 0.017
transport GO:0006810 220 0.017
cellular homeostasis GO:0019725 26 0.017
endoplasmic reticulum unfolded protein response GO:0030968 2 0.017
sequestering of metal ion GO:0051238 3 0.017
myotube differentiation GO:0014902 45 0.017
positive regulation of gene expression GO:0010628 71 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of striated muscle contraction GO:0006942 2 0.017
directional locomotion GO:0033058 1 0.017
regulation of defense response to virus GO:0050688 2 0.017
dopamine metabolic process GO:0042417 2 0.017
regulation of rna metabolic process GO:0051252 224 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
specification of symmetry GO:0009799 204 0.016
cellular component movement GO:0006928 335 0.016
Fly
regulation of cellular component organization GO:0051128 86 0.016
small molecule catabolic process GO:0044282 3 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
regulation of sarcomere organization GO:0060297 2 0.016
muscle tissue morphogenesis GO:0060415 7 0.016
lamellipodium assembly GO:0030032 1 0.016
axonogenesis GO:0007409 152 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
regulation of organelle organization GO:0033043 29 0.016
cell motility GO:0048870 244 0.016
cell projection assembly GO:0030031 64 0.016
positive regulation of catabolic process GO:0009896 4 0.016
programmed cell death GO:0012501 119 0.016
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.015
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.015
localization of cell GO:0051674 244 0.015
multicellular organismal macromolecule metabolic process GO:0044259 2 0.015
cellular response to unfolded protein GO:0034620 2 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
hematopoietic stem cell differentiation GO:0060218 20 0.015
regulation of signaling GO:0023051 235 0.015
renal system development GO:0072001 94 0.015
ras protein signal transduction GO:0007265 7 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of systemic arterial blood pressure GO:0003073 1 0.015
regulation of cytokine mediated signaling pathway GO:0001959 3 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of membrane potential GO:0042391 23 0.014
single organism reproductive process GO:0044702 40 0.014
brain development GO:0007420 293 0.014
calcium ion homeostasis GO:0055074 19 0.014
positive regulation of secretion GO:0051047 1 0.014
muscle organ development GO:0007517 101 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of primary metabolic process GO:0080090 311 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
response to stress GO:0006950 263 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
head development GO:0060322 303 0.014
appendage development GO:0048736 80 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
pronephros development GO:0048793 69 0.013
cardiac ventricle morphogenesis GO:0003208 7 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
histone h3 k4 methylation GO:0051568 2 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
cellular protein metabolic process GO:0044267 129 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of mrna processing GO:0050684 3 0.013
notochord development GO:0030903 54 0.013
regulation of transporter activity GO:0032409 2 0.013
post embryonic organ development GO:0048569 4 0.013
macromolecule modification GO:0043412 111 0.013
microtubule organizing center organization GO:0031023 1 0.013
hormone transport GO:0009914 2 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
small molecule biosynthetic process GO:0044283 16 0.013
gamete generation GO:0007276 33 0.013
response to vitamin GO:0033273 3 0.012
immune system process GO:0002376 241 0.012
peptide transport GO:0015833 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
ribonucleotide metabolic process GO:0009259 27 0.012
adherens junction organization GO:0034332 4 0.012
behavior GO:0007610 74 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
nucleic acid templated transcription GO:0097659 181 0.012
protein complex disassembly GO:0043241 1 0.012
regulation of locomotion GO:0040012 55 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
hormone secretion GO:0046879 2 0.012
taxis GO:0042330 109 0.012
glucose homeostasis GO:0042593 1 0.012
actin filament based movement GO:0030048 1 0.012
Fly
defense response to other organism GO:0098542 33 0.012
extracellular matrix organization GO:0030198 27 0.012
developmental process involved in reproduction GO:0003006 27 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
regulation of p38mapk cascade GO:1900744 1 0.011
regulation of cell differentiation GO:0045595 142 0.011
protein localization to plasma membrane GO:0072659 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
fatty acid beta oxidation GO:0006635 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cellular metal ion homeostasis GO:0006875 16 0.011
apoptotic process involved in development GO:1902742 2 0.011
female gamete generation GO:0007292 14 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
atrial cardiac muscle cell development GO:0055014 4 0.011
digestive system development GO:0055123 289 0.011
regulation of programmed cell death GO:0043067 101 0.011
translational initiation GO:0006413 3 0.011
protein complex biogenesis GO:0070271 30 0.011
growth GO:0040007 174 0.011
water homeostasis GO:0030104 4 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
catabolic process GO:0009056 32 0.011
metal ion homeostasis GO:0055065 26 0.011
chemical homeostasis GO:0048878 49 0.011
macromolecule biosynthetic process GO:0009059 227 0.010
notochord cell differentiation GO:0060034 18 0.010
basement membrane assembly GO:0070831 3 0.010
carbohydrate derivative biosynthetic process GO:1901137 43 0.010
protein import GO:0017038 3 0.010
positive regulation of striated muscle cell differentiation GO:0051155 1 0.010
regulation of autophagy GO:0010506 3 0.010
organic acid biosynthetic process GO:0016053 12 0.010
regulation of cell development GO:0060284 100 0.010
cell matrix adhesion GO:0007160 4 0.010
regulation of transcription dna templated GO:0006355 213 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
calcium ion import GO:0070509 4 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
regulation of gene expression GO:0010468 265 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
negative regulation of cytokine production GO:0001818 1 0.010
double strand break repair GO:0006302 3 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
organophosphate metabolic process GO:0019637 37 0.010
regulation of phosphate metabolic process GO:0019220 43 0.010
oocyte differentiation GO:0009994 14 0.010
nucleoside monophosphate metabolic process GO:0009123 6 0.010
regulation of apoptotic process GO:0042981 98 0.010

myl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.137
musculoskeletal system disease DOID:17 0 0.137
distal arthrogryposis DOID:0050646 0 0.132
muscular disease DOID:0080000 0 0.132
muscle tissue disease DOID:66 0 0.132
cardiovascular system disease DOID:1287 0 0.038
myopathy DOID:423 0 0.017
heart disease DOID:114 0 0.017
cardiomyopathy DOID:0050700 0 0.017
intrinsic cardiomyopathy DOID:0060036 0 0.015