Danio rerio

0 known processes

prrx1a

paired related homeobox 1a

(Aliases: wu:fb52c01,zgc:64055,cb329,prrx1,pmx1,wu:fa09h05)

prrx1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.788
regulation of nucleic acid templated transcription GO:1903506 213 0.773
Rat
regulation of transcription dna templated GO:0006355 213 0.728
Rat
cellular aromatic compound metabolic process GO:0006725 295 0.641
Rat
heterocycle biosynthetic process GO:0018130 215 0.610
Rat
muscle structure development GO:0061061 196 0.593
positive regulation of cellular process GO:0048522 201 0.576
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.568
Rat
negative regulation of myeloid cell differentiation GO:0045638 1 0.568
nucleic acid metabolic process GO:0090304 244 0.553
Rat
regulation of multicellular organismal development GO:2000026 223 0.552
regulation of chondrocyte differentiation GO:0032330 1 0.544
multicellular organismal metabolic process GO:0044236 2 0.529
response to chemical GO:0042221 320 0.525
organic substance biosynthetic process GO:1901576 289 0.502
Rat
nucleic acid templated transcription GO:0097659 181 0.500
Rat
outflow tract morphogenesis GO:0003151 1 0.493
skeletal system development GO:0001501 181 0.484
Mouse
regulation of cell development GO:0060284 100 0.475
biosynthetic process GO:0009058 294 0.472
Rat
appendage morphogenesis GO:0035107 56 0.472
Mouse
muscle organ development GO:0007517 101 0.464
signal transduction GO:0007165 455 0.458
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.427
Zebrafish Rat
rna metabolic process GO:0016070 219 0.420
Rat
nitrogen compound metabolic process GO:0006807 319 0.418
Rat
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.411
Mouse
positive regulation of biological process GO:0048518 253 0.401
Zebrafish Mouse
central nervous system development GO:0007417 387 0.401
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.399
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.394
Rat
skeletal system morphogenesis GO:0048705 102 0.383
Mouse
cartilage development GO:0051216 96 0.370
Mouse
response to nutrient GO:0007584 3 0.361
response to organic substance GO:0010033 153 0.360
mesenchymal cell proliferation GO:0010463 1 0.353
Mouse
blood vessel development GO:0001568 246 0.348
Mouse
specification of symmetry GO:0009799 204 0.342
nucleobase containing compound biosynthetic process GO:0034654 205 0.342
Rat
multicellular organismal macromolecule metabolic process GO:0044259 2 0.335
regionalization GO:0003002 274 0.328
stem cell proliferation GO:0072089 4 0.315
Mouse
gene expression GO:0010467 252 0.314
Zebrafish Rat
cell fate commitment GO:0045165 99 0.312
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.312
Rat
gastrulation GO:0007369 208 0.311
regulation of cell differentiation GO:0045595 142 0.303
response to vitamin GO:0033273 3 0.295
cell proliferation GO:0008283 80 0.292
Mouse
heart morphogenesis GO:0003007 156 0.290
embryonic skeletal system morphogenesis GO:0048704 93 0.289
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.279
Rat
cellular component morphogenesis GO:0032989 336 0.274
rna biosynthetic process GO:0032774 181 0.270
Rat
collagen metabolic process GO:0032963 2 0.257
neuron development GO:0048666 262 0.247
heterocycle metabolic process GO:0046483 290 0.241
Rat
generation of neurons GO:0048699 385 0.236
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.225
Rat
cellular biosynthetic process GO:0044249 286 0.222
Rat
regulation of rna biosynthetic process GO:2001141 213 0.218
Rat
negative regulation of cellular process GO:0048523 283 0.218
Rat
specification of organ identity GO:0010092 2 0.217
cell migration involved in gastrulation GO:0042074 79 0.213
regulation of primary metabolic process GO:0080090 311 0.212
Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.204
Rat
digestive tract morphogenesis GO:0048546 231 0.200
positive regulation of response to stimulus GO:0048584 80 0.197
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.196
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.188
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.187
Rat
cell surface receptor signaling pathway GO:0007166 325 0.187
Mouse
mesoderm formation GO:0001707 43 0.172
regulation of response to stimulus GO:0048583 269 0.170
Mouse
regulation of neurogenesis GO:0050767 87 0.169
muscle cell differentiation GO:0042692 139 0.166
morphogenesis of an epithelium GO:0002009 333 0.165
tissue migration GO:0090130 37 0.165
regulation of cellular biosynthetic process GO:0031326 245 0.163
Rat
regulation of rna metabolic process GO:0051252 224 0.161
Rat
immune system process GO:0002376 241 0.158
regulation of signaling GO:0023051 235 0.157
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.157
neuron projection development GO:0031175 180 0.156
mesoderm morphogenesis GO:0048332 51 0.154
formation of primary germ layer GO:0001704 62 0.152
macromolecule biosynthetic process GO:0009059 227 0.151
Rat
muscle fiber development GO:0048747 52 0.151
embryonic organ development GO:0048568 381 0.144
Mouse
regulation of biosynthetic process GO:0009889 250 0.144
Rat
glial cell migration GO:0008347 3 0.142
skeletal muscle organ development GO:0060538 78 0.142
positive regulation of stem cell proliferation GO:2000648 1 0.141
Mouse
axon choice point recognition GO:0016198 5 0.139
inner ear morphogenesis GO:0042472 63 0.138
Mouse
regulation of dna replication GO:0006275 3 0.136
pericardium morphogenesis GO:0003344 1 0.134
sequestering of calcium ion GO:0051208 3 0.134
negative regulation of biological process GO:0048519 304 0.132
Rat
determination of bilateral symmetry GO:0009855 204 0.132
regulation of developmental process GO:0050793 247 0.131
tube morphogenesis GO:0035239 349 0.131
brain development GO:0007420 293 0.130
Zebrafish
death GO:0016265 121 0.128
cell projection organization GO:0030030 284 0.128
transcription dna templated GO:0006351 181 0.127
Rat
regulation of anatomical structure morphogenesis GO:0022603 130 0.127
cellular response to extracellular stimulus GO:0031668 2 0.126
neuron differentiation GO:0030182 353 0.124
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.123
Rat
cellular macromolecule metabolic process GO:0044260 391 0.122
Rat
cell migration involved in heart development GO:0060973 22 0.121
axon guidance GO:0007411 86 0.121
embryonic skeletal system development GO:0048706 97 0.121
Mouse
muscle cell development GO:0055001 115 0.120
pericardium development GO:0060039 1 0.119
stem cell maintenance GO:0019827 4 0.118
cell death GO:0008219 121 0.118
aromatic compound biosynthetic process GO:0019438 217 0.115
Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.115
Rat
bone morphogenesis GO:0060349 11 0.113
regulation of macromolecule biosynthetic process GO:0010556 225 0.111
Rat
embryonic organ morphogenesis GO:0048562 274 0.109
Mouse
head development GO:0060322 303 0.109
Zebrafish
immune system development GO:0002520 191 0.108
mesoderm development GO:0007498 88 0.108
blood vessel morphogenesis GO:0048514 216 0.108
Mouse
positive regulation of smoothened signaling pathway GO:0045880 5 0.107
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.107
regulation of synapse organization GO:0050807 3 0.107
sensory organ development GO:0007423 393 0.107
Mouse
hard palate development GO:0060022 4 0.105
embryonic appendage morphogenesis GO:0035113 30 0.105
Mouse
limb development GO:0060173 8 0.105
Mouse
apoptotic process GO:0006915 116 0.104
embryonic heart tube development GO:0035050 133 0.103
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.103
single organism metabolic process GO:0044710 217 0.103
regulation of epithelial cell proliferation GO:0050678 3 0.103
regulation of cell proliferation GO:0042127 37 0.102
Mouse
epithelial tube morphogenesis GO:0060562 148 0.099
dorsal ventral pattern formation GO:0009953 125 0.098
digestive system development GO:0055123 289 0.098
digestive tract development GO:0048565 265 0.097
sympathetic nervous system development GO:0048485 3 0.097
Zebrafish
positive regulation of histone deacetylation GO:0031065 1 0.095
positive regulation of nucleic acid templated transcription GO:1903508 57 0.093
striated muscle cell differentiation GO:0051146 129 0.093
cell adhesion mediated by integrin GO:0033627 1 0.092
hindbrain development GO:0030902 91 0.091
Zebrafish
pharyngeal system development GO:0060037 18 0.090
negative regulation of gene expression GO:0010629 65 0.090
Rat
central nervous system neuron differentiation GO:0021953 74 0.089
cell morphogenesis involved in differentiation GO:0000904 195 0.089
cellular component movement GO:0006928 335 0.089
regulation of cellular component organization GO:0051128 86 0.088
regulation of cytokine production GO:0001817 3 0.088
muscle tissue development GO:0060537 110 0.088
negative regulation of transcription dna templated GO:0045892 45 0.087
Rat
cellular response to organic substance GO:0071310 105 0.086
eye morphogenesis GO:0048592 144 0.085
sensory organ morphogenesis GO:0090596 200 0.084
Mouse
regulation of synapse assembly GO:0051963 3 0.084
positive regulation of cell adhesion GO:0045785 1 0.084
camera type eye development GO:0043010 222 0.083
regulation of signal transduction GO:0009966 225 0.083
Mouse
connective tissue development GO:0061448 99 0.082
Mouse
positive regulation of metabolic process GO:0009893 108 0.081
Zebrafish
heart jogging GO:0003146 40 0.081
larval development GO:0002164 2 0.081
determination of left right symmetry GO:0007368 179 0.080
chordate embryonic development GO:0043009 271 0.079
Mouse
regulation of gene expression GO:0010468 265 0.079
Zebrafish Rat
regulation of stem cell proliferation GO:0072091 2 0.079
Mouse
morphogenesis of a branching structure GO:0001763 21 0.075
negative regulation of multicellular organismal process GO:0051241 69 0.075
limb bud formation GO:0060174 2 0.074
determination of heart left right asymmetry GO:0061371 117 0.073
programmed cell death GO:0012501 119 0.072
fin morphogenesis GO:0033334 53 0.072
response to external stimulus GO:0009605 264 0.071
ameboidal type cell migration GO:0001667 143 0.071
positive regulation of gene expression GO:0010628 71 0.071
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 55 0.071
Rat
positive regulation of multicellular organismal process GO:0051240 52 0.070
organ formation GO:0048645 17 0.070
collagen fibril organization GO:0030199 1 0.070
positive regulation of nervous system development GO:0051962 25 0.068
positive regulation of cytokine production GO:0001819 2 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.066
Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.066
regulation of apoptotic process GO:0042981 98 0.065
pons development GO:0021548 11 0.065
Zebrafish
negative regulation of endodermal cell differentiation GO:1903225 8 0.065
signal transduction in absence of ligand GO:0038034 1 0.065
transcription from rna polymerase ii promoter GO:0006366 80 0.063
Rat
protein acylation GO:0043543 3 0.062
epithelial cell migration GO:0010631 25 0.061
developmental growth GO:0048589 166 0.061
regulation of establishment of protein localization GO:0070201 4 0.061
positive regulation of developmental process GO:0051094 50 0.060
heart looping GO:0001947 94 0.060
negative regulation of neuron differentiation GO:0045665 10 0.059
limb morphogenesis GO:0035108 7 0.059
Mouse
response to stress GO:0006950 263 0.059
growth GO:0040007 174 0.059
positive regulation of cell proliferation GO:0008284 15 0.058
Mouse
catenin import into nucleus GO:0035411 2 0.058
artery morphogenesis GO:0048844 14 0.058
Mouse
organelle organization GO:0006996 227 0.058
cell part morphogenesis GO:0032990 246 0.057
cell projection morphogenesis GO:0048858 244 0.057
response to drug GO:0042493 3 0.056
regulation of cell communication GO:0010646 232 0.056
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.056
Rat
single organism organelle organization GO:1902589 199 0.056
nuclear transport GO:0051169 4 0.055
cell proliferation involved in heart morphogenesis GO:0061323 2 0.055
extracellular structure organization GO:0043062 27 0.055
regulation of stem cell differentiation GO:2000736 4 0.055
cell fate specification GO:0001708 68 0.055
gland development GO:0048732 143 0.054
central nervous system projection neuron axonogenesis GO:0021952 15 0.054
protein import GO:0017038 3 0.054
axon development GO:0061564 166 0.053
fin development GO:0033333 77 0.053
embryonic viscerocranium morphogenesis GO:0048703 52 0.053
endothelium development GO:0003158 25 0.053
macromolecular complex subunit organization GO:0043933 74 0.053
regulation of cartilage development GO:0061035 7 0.053
striated muscle tissue development GO:0014706 110 0.052
positive regulation of signal transduction GO:0009967 56 0.052
Mouse
myotube differentiation GO:0014902 45 0.052
negative regulation of developmental process GO:0051093 65 0.052
chondrocyte development GO:0002063 4 0.051
hematopoietic or lymphoid organ development GO:0048534 191 0.051
inner ear development GO:0048839 126 0.050
Mouse
craniofacial suture morphogenesis GO:0097094 2 0.050
striated muscle cell development GO:0055002 108 0.050
regulation of nervous system development GO:0051960 90 0.049
regulation of biological quality GO:0065008 263 0.049
positive regulation of neurogenesis GO:0050769 24 0.049
positive regulation of response to external stimulus GO:0032103 9 0.049
urogenital system development GO:0001655 97 0.049
response to corticosteroid GO:0031960 1 0.049
ear development GO:0043583 127 0.048
Mouse
vasculature development GO:0001944 278 0.048
Mouse
negative regulation of cell death GO:0060548 60 0.048
regulation of nucleocytoplasmic transport GO:0046822 2 0.048
positive regulation of cell communication GO:0010647 56 0.047
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.047
regulation of cytoplasmic transport GO:1903649 4 0.046
positive regulation of endothelial cell proliferation GO:0001938 1 0.046
nucleocytoplasmic transport GO:0006913 4 0.046
neuron projection morphogenesis GO:0048812 161 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.045
protein metabolic process GO:0019538 183 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
positive regulation of signaling GO:0023056 56 0.045
Mouse
response to carbohydrate GO:0009743 3 0.045
determination of dorsal ventral asymmetry GO:0048262 34 0.044
cell migration GO:0016477 237 0.044
regulation of inflammatory response GO:0050727 2 0.044
regulation of metabolic process GO:0019222 359 0.043
Zebrafish Rat
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.043
photoreceptor cell fate commitment GO:0046552 1 0.043
negative regulation of cell differentiation GO:0045596 46 0.043
bone development GO:0060348 14 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.042
negative regulation of leukocyte differentiation GO:1902106 1 0.042
pectoral fin development GO:0033339 50 0.042
cell motility GO:0048870 244 0.041
renal system development GO:0072001 94 0.041
stem cell division GO:0017145 1 0.041
carboxylic acid metabolic process GO:0019752 22 0.040
cellular response to nutrient levels GO:0031669 2 0.040
sensory perception of chemical stimulus GO:0007606 3 0.040
palate development GO:0060021 8 0.039
Mouse
homeostatic process GO:0042592 142 0.039
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.039
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
developmental growth involved in morphogenesis GO:0060560 86 0.039
single organism localization GO:1902578 225 0.038
cellular ketone metabolic process GO:0042180 11 0.038
nuclear import GO:0051170 3 0.038
eye development GO:0001654 277 0.038
cardiac atrium morphogenesis GO:0003209 2 0.037
mesodermal cell differentiation GO:0048333 21 0.037
myeloid cell differentiation GO:0030099 86 0.037
developmental cell growth GO:0048588 52 0.037
ganglion development GO:0061548 5 0.037
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.036
erythrocyte differentiation GO:0030218 54 0.036
positive regulation of neuron projection development GO:0010976 9 0.036
cellular response to estradiol stimulus GO:0071392 1 0.036
regulation of neuron projection development GO:0010975 40 0.036
regulation of protein targeting GO:1903533 2 0.036
cell morphogenesis GO:0000902 289 0.036
nephron epithelium morphogenesis GO:0072088 1 0.036
epithelium migration GO:0090132 25 0.036
camera type eye morphogenesis GO:0048593 108 0.036
regulation of epithelial cell migration GO:0010632 5 0.035
anatomical structure homeostasis GO:0060249 36 0.035
wound healing GO:0042060 90 0.035
positive regulation of cell development GO:0010720 25 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.035
Rat
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.035
positive regulation of programmed cell death GO:0043068 29 0.035
single organism nuclear import GO:1902593 3 0.034
oxoacid metabolic process GO:0043436 31 0.034
negative regulation of cell development GO:0010721 26 0.034
regeneration GO:0031099 91 0.034
myeloid leukocyte differentiation GO:0002573 15 0.033
localization of cell GO:0051674 244 0.033
response to glucocorticoid GO:0051384 1 0.033
cellular response to lipopolysaccharide GO:0071222 3 0.033
negative regulation of bmp signaling pathway GO:0030514 13 0.033
angiogenesis GO:0001525 158 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
tissue regeneration GO:0042246 74 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.033
Rat
aging GO:0007568 2 0.032
response to amino acid GO:0043200 2 0.032
neural nucleus development GO:0048857 15 0.032
Zebrafish
cellular response to external stimulus GO:0071496 2 0.031
response to abiotic stimulus GO:0009628 122 0.031
establishment of localization GO:0051234 244 0.031
ear morphogenesis GO:0042471 64 0.031
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.031
cell cycle g1 s phase transition GO:0044843 1 0.031
negative regulation of neurogenesis GO:0050768 20 0.030
tissue remodeling GO:0048771 4 0.030
cell growth GO:0016049 57 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
single fertilization GO:0007338 3 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.030
endothelial cell differentiation GO:0045446 20 0.030
embryonic hemopoiesis GO:0035162 53 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
negative regulation of signaling GO:0023057 96 0.029
post embryonic organ development GO:0048569 4 0.029
regulation of protein import into nucleus GO:0042306 2 0.029
negative regulation of apoptotic process GO:0043066 55 0.029
regulation of neuron differentiation GO:0045664 56 0.029
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.028
regulation of multicellular organismal process GO:0051239 277 0.028
macromolecule modification GO:0043412 111 0.028
metencephalon development GO:0022037 27 0.028
Zebrafish
positive regulation of cell death GO:0010942 29 0.028
protein stabilization GO:0050821 2 0.028
positive regulation of histone modification GO:0031058 1 0.028
positive regulation of chemotaxis GO:0050921 5 0.028
regulation of cell projection organization GO:0031344 44 0.028
muscle organ morphogenesis GO:0048644 8 0.028
response to lipid GO:0033993 60 0.028
positive regulation of apoptotic process GO:0043065 29 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.027
Rat
regulation of chemotaxis GO:0050920 18 0.027
protein localization to nucleus GO:0034504 3 0.027
embryonic eye morphogenesis GO:0048048 30 0.027
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.027
septum transversum development GO:0003343 4 0.027
endothelial cell migration GO:0043542 19 0.027
retina morphogenesis in camera type eye GO:0060042 79 0.027
regulation of epithelial to mesenchymal transition GO:0010717 3 0.027
dendrite development GO:0016358 9 0.027
positive regulation of biosynthetic process GO:0009891 68 0.027
organic acid metabolic process GO:0006082 31 0.026
negative regulation of cell communication GO:0010648 96 0.025
stem cell development GO:0048864 82 0.025
osteoclast differentiation GO:0030316 1 0.025
cellular response to lipid GO:0071396 39 0.025
regulation of multicellular organismal metabolic process GO:0044246 2 0.025
negative regulation of muscle tissue development GO:1901862 2 0.025
cardiac atrium development GO:0003230 4 0.025
regulation of programmed cell death GO:0043067 101 0.025
regulation of intracellular signal transduction GO:1902531 57 0.025
cartilage morphogenesis GO:0060536 13 0.025
protein acetylation GO:0006473 2 0.024
anterior posterior pattern specification GO:0009952 152 0.024
heart valve formation GO:0003188 4 0.024
germ line stem cell maintenance GO:0030718 2 0.024
atrioventricular valve formation GO:0003190 3 0.024
regulation of catenin import into nucleus GO:0035412 2 0.024
response to growth factor GO:0070848 39 0.024
heart valve morphogenesis GO:0003179 8 0.024
cellular response to endogenous stimulus GO:0071495 68 0.024
regulation of bmp signaling pathway GO:0030510 39 0.023
alcohol biosynthetic process GO:0046165 2 0.023
sprouting angiogenesis GO:0002040 53 0.023
heart formation GO:0060914 13 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
positive regulation of cell differentiation GO:0045597 30 0.023
axon extension GO:0048675 45 0.023
establishment of protein localization to plasma membrane GO:0090002 1 0.023
atrioventricular valve morphogenesis GO:0003181 6 0.023
regulation of response to external stimulus GO:0032101 31 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.023
enteric nervous system development GO:0048484 12 0.023
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.023
olfactory placode development GO:0071698 12 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
regulation of collagen metabolic process GO:0010712 2 0.022
negative regulation of stem cell differentiation GO:2000737 2 0.022
sympathetic ganglion development GO:0061549 2 0.022
Zebrafish
cellular component assembly GO:0022607 170 0.022
negative regulation of epithelial cell proliferation GO:0050680 1 0.022
axonogenesis GO:0007409 152 0.022
regulation of binding GO:0051098 3 0.022
positive regulation of locomotion GO:0040017 14 0.022
neural retina development GO:0003407 49 0.022
skeletal muscle tissue development GO:0007519 67 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
Rat
negative regulation of nervous system development GO:0051961 22 0.021
regulation of axon extension GO:0030516 24 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.021
Rat
negative regulation of cellular metabolic process GO:0031324 77 0.021
Rat
neuron projection extension GO:1990138 45 0.021
cell cycle GO:0007049 93 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
positive regulation of protein deacetylation GO:0090312 1 0.020
embryonic camera type eye development GO:0031076 29 0.020
defense response GO:0006952 47 0.020
positive regulation of immune response GO:0050778 11 0.020
negative regulation of biosynthetic process GO:0009890 55 0.020
Rat
cellular amine metabolic process GO:0044106 2 0.020
cranial suture morphogenesis GO:0060363 1 0.020
regulation of reproductive process GO:2000241 4 0.020
polarized epithelial cell differentiation GO:0030859 4 0.020
regulation of endothelial cell proliferation GO:0001936 1 0.020
regulation of cell growth GO:0001558 29 0.019
regulation of histone deacetylation GO:0031063 2 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.019
negative regulation of signal transduction GO:0009968 94 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of cell morphogenesis GO:0022604 42 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
negative regulation of immune system process GO:0002683 7 0.019
stem cell differentiation GO:0048863 117 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.018
tissue homeostasis GO:0001894 25 0.018
chondrocyte differentiation GO:0002062 7 0.018
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
Rat
pectoral fin morphogenesis GO:0035138 29 0.018
retinoic acid receptor signaling pathway GO:0048384 16 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
fat soluble vitamin metabolic process GO:0006775 4 0.018
regulation of axonogenesis GO:0050770 32 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
regulation of hormone secretion GO:0046883 2 0.018
dendrite morphogenesis GO:0048813 5 0.018
regulation of cellular component movement GO:0051270 55 0.018
morphogenesis of an epithelial fold GO:0060571 1 0.017
cardiac muscle cell differentiation GO:0055007 30 0.017
bmp signaling pathway involved in heart development GO:0061312 15 0.017
cellular protein metabolic process GO:0044267 129 0.017
single organism biosynthetic process GO:0044711 71 0.017
amine metabolic process GO:0009308 2 0.017
single organism transport GO:0044765 206 0.017
regulation of vasculature development GO:1901342 33 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
positive regulation of transport GO:0051050 2 0.017
carbohydrate homeostasis GO:0033500 1 0.017
cytosolic calcium ion transport GO:0060401 3 0.017
embryonic digestive tract development GO:0048566 4 0.017
somatic stem cell maintenance GO:0035019 1 0.017
organic substance transport GO:0071702 58 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
positive regulation of cell cycle GO:0045787 3 0.016
response to organic cyclic compound GO:0014070 51 0.016
response to endogenous stimulus GO:0009719 83 0.016
leukocyte migration GO:0050900 15 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.016
retina layer formation GO:0010842 24 0.016
cell cell signaling involved in cell fate commitment GO:0045168 12 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
sarcomere organization GO:0045214 26 0.016
mesenchymal cell development GO:0014031 78 0.016
regulation of cell death GO:0010941 103 0.016
response to hormone GO:0009725 48 0.016

prrx1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.176
disease of anatomical entity DOID:7 0 0.176
musculoskeletal system disease DOID:17 0 0.176
connective tissue disease DOID:65 0 0.176
charcot marie tooth disease type 4 DOID:0050541 0 0.018
neuromuscular disease DOID:440 0 0.018
charcot marie tooth disease DOID:10595 0 0.018
nervous system disease DOID:863 0 0.018
neuropathy DOID:870 0 0.018