Danio rerio

0 known processes

capns1a

calpain, small subunit 1 a

(Aliases: wu:fb81g08,zgc:110603,wu:fl09e04,capns1,cb616)

capns1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intestinal absorption GO:0050892 2 0.849
negative regulation of protein transport GO:0051224 3 0.790
plasma membrane repair GO:0001778 2 0.431
negative regulation of multicellular organismal process GO:0051241 69 0.308
regulation of protein transport GO:0051223 3 0.303
regulation of establishment of protein localization GO:0070201 4 0.246
protein import into nucleus GO:0006606 3 0.233
transport GO:0006810 220 0.233
death GO:0016265 121 0.207
lipid digestion GO:0044241 3 0.190
protein localization to nucleus GO:0034504 3 0.177
positive regulation of transport GO:0051050 2 0.176
cilium morphogenesis GO:0060271 85 0.170
single organism localization GO:1902578 225 0.170
single organism organelle organization GO:1902589 199 0.169
protein targeting to nucleus GO:0044744 3 0.161
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.157
regulation of multicellular organismal development GO:2000026 223 0.153
cellular response to chemical stimulus GO:0070887 157 0.145
membrane fusion GO:0061025 2 0.126
establishment of protein localization to organelle GO:0072594 4 0.126
regulation of protein localization to nucleus GO:1900180 2 0.115
response to organic substance GO:0010033 153 0.105
nuclear import GO:0051170 3 0.104
intestinal cholesterol absorption GO:0030299 2 0.103
protein import GO:0017038 3 0.103
nucleocytoplasmic transport GO:0006913 4 0.098
single organism transport GO:0044765 206 0.097
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.091
cell death GO:0008219 121 0.089
regulation of programmed cell death GO:0043067 101 0.089
regulation of cytoplasmic transport GO:1903649 4 0.087
nuclear transport GO:0051169 4 0.084
programmed cell death GO:0012501 119 0.084
cell projection organization GO:0030030 284 0.083
signal transduction GO:0007165 455 0.083
regulation of protein import into nucleus GO:0042306 2 0.082
organic hydroxy compound transport GO:0015850 14 0.081
multicellular organism growth GO:0035264 4 0.077
regulation of binding GO:0051098 3 0.074
negative regulation of protein localization to nucleus GO:1900181 2 0.073
proximal distal pattern formation GO:0009954 1 0.071
organic acid metabolic process GO:0006082 31 0.070
negative regulation of protein import into nucleus GO:0042308 2 0.069
negative regulation of biological process GO:0048519 304 0.069
negative regulation of intracellular transport GO:0032387 3 0.068
organonitrogen compound metabolic process GO:1901564 74 0.067
oxoacid metabolic process GO:0043436 31 0.063
immune system development GO:0002520 191 0.062
endomembrane system organization GO:0010256 13 0.062
positive regulation of cellular component biogenesis GO:0044089 3 0.061
phagocytosis GO:0006909 3 0.061
aging GO:0007568 2 0.060
response to chemical GO:0042221 320 0.060
protein localization GO:0008104 40 0.060
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.060
organelle organization GO:0006996 227 0.060
regulation of cell death GO:0010941 103 0.060
positive regulation of biological process GO:0048518 253 0.059
wound healing GO:0042060 90 0.059
regulation of apoptotic process GO:0042981 98 0.059
single organism membrane organization GO:0044802 20 0.059
regulation of cytokine production GO:0001817 3 0.058
regulation of nucleocytoplasmic transport GO:0046822 2 0.058
response to oxygen containing compound GO:1901700 55 0.057
positive regulation of cell cycle GO:0045787 3 0.057
long chain fatty acid transport GO:0015909 1 0.056
specification of symmetry GO:0009799 204 0.055
positive regulation of defense response to virus by host GO:0002230 0 0.055
response to stress GO:0006950 263 0.055
determination of bilateral symmetry GO:0009855 204 0.055
small molecule metabolic process GO:0044281 77 0.054
regulation of protein targeting GO:1903533 2 0.052
protein secretion GO:0009306 1 0.051
epithelial cell differentiation GO:0030855 116 0.051
regulation of intracellular protein transport GO:0033157 3 0.050
gene expression GO:0010467 252 0.050
negative regulation of cytokine production GO:0001818 1 0.050
humoral immune response GO:0006959 5 0.049
cytokinesis GO:0000910 3 0.049
cellular response to organic substance GO:0071310 105 0.048
single organism nuclear import GO:1902593 3 0.048
actin polymerization or depolymerization GO:0008154 2 0.048
negative regulation of cellular process GO:0048523 283 0.048
skin development GO:0043588 54 0.047
positive regulation of endothelial cell migration GO:0010595 2 0.047
cellular response to hormone stimulus GO:0032870 39 0.046
aromatic compound biosynthetic process GO:0019438 217 0.046
reflex GO:0060004 2 0.046
positive regulation of cellular process GO:0048522 201 0.046
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.044
regulation of multicellular organismal process GO:0051239 277 0.044
cell morphogenesis GO:0000902 289 0.043
negative regulation of cytoplasmic transport GO:1903650 2 0.043
single organism membrane fusion GO:0044801 2 0.043
regulation of endothelial cell proliferation GO:0001936 1 0.043
organelle fusion GO:0048284 3 0.042
negative regulation of intracellular protein transport GO:0090317 3 0.042
cellular component biogenesis GO:0044085 178 0.041
maintenance of location GO:0051235 4 0.041
organic substance transport GO:0071702 58 0.040
regulation of biological quality GO:0065008 263 0.040
single organism metabolic process GO:0044710 217 0.040
adult behavior GO:0030534 2 0.040
keratinocyte differentiation GO:0030216 0 0.039
myeloid cell homeostasis GO:0002262 56 0.039
establishment of localization GO:0051234 244 0.039
cell projection morphogenesis GO:0048858 244 0.038
cognition GO:0050890 1 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
cellular macromolecule metabolic process GO:0044260 391 0.036
immune system process GO:0002376 241 0.035
negative regulation of epithelial cell proliferation GO:0050680 1 0.035
hemopoiesis GO:0030097 183 0.035
regulation of cellular component movement GO:0051270 55 0.035
cellular component assembly involved in morphogenesis GO:0010927 107 0.035
carboxylic acid metabolic process GO:0019752 22 0.034
regulation of epithelial cell proliferation GO:0050678 3 0.034
extrinsic apoptotic signaling pathway GO:0097191 3 0.034
cell cycle process GO:0022402 53 0.034
single organism cellular localization GO:1902580 46 0.034
positive regulation of apoptotic signaling pathway GO:2001235 1 0.034
developmental growth GO:0048589 166 0.033
negative regulation of secretion by cell GO:1903531 2 0.033
regulation of cellular component organization GO:0051128 86 0.032
regulation of wound healing GO:0061041 2 0.032
axonogenesis GO:0007409 152 0.032
peptide transport GO:0015833 1 0.032
regulation of blood coagulation GO:0030193 1 0.032
behavior GO:0007610 74 0.032
larval development GO:0002164 2 0.031
tissue regeneration GO:0042246 74 0.031
negative regulation of kinase activity GO:0033673 4 0.031
cellular response to lipopolysaccharide GO:0071222 3 0.030
brain development GO:0007420 293 0.030
wnt signaling pathway GO:0016055 80 0.030
growth GO:0040007 174 0.030
erk1 and erk2 cascade GO:0070371 4 0.030
membrane invagination GO:0010324 1 0.030
ion transport GO:0006811 114 0.030
glucose homeostasis GO:0042593 1 0.029
mitotic cell cycle embryonic GO:0045448 2 0.029
negative regulation of nuclear division GO:0051784 3 0.028
regulation of response to stimulus GO:0048583 269 0.028
regulation of erk1 and erk2 cascade GO:0070372 4 0.028
response to inorganic substance GO:0010035 38 0.027
positive regulation of signal transduction GO:0009967 56 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
response to external biotic stimulus GO:0043207 97 0.027
sensory organ development GO:0007423 393 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
localization of cell GO:0051674 244 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.026
determination of left right symmetry GO:0007368 179 0.026
fin regeneration GO:0031101 51 0.026
cellular component movement GO:0006928 335 0.026
cellular response to biotic stimulus GO:0071216 3 0.026
meiotic nuclear division GO:0007126 4 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
actin filament polymerization GO:0030041 2 0.026
transcription dna templated GO:0006351 181 0.026
macromolecule localization GO:0033036 54 0.026
vesicle mediated transport GO:0016192 22 0.025
regulation of cell differentiation GO:0045595 142 0.025
cell proliferation GO:0008283 80 0.025
extracellular structure organization GO:0043062 27 0.025
regulation of cell motility GO:2000145 46 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
cell part morphogenesis GO:0032990 246 0.024
positive regulation of cell adhesion GO:0045785 1 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of cell proliferation GO:0042127 37 0.024
regulation of immune system process GO:0002682 34 0.024
positive regulation of cell death GO:0010942 29 0.024
rna biosynthetic process GO:0032774 181 0.024
response to corticosteroid GO:0031960 1 0.024
vasculature development GO:0001944 278 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of developmental process GO:0050793 247 0.023
cellular ketone metabolic process GO:0042180 11 0.023
apoptotic process GO:0006915 116 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
dorsal ventral pattern formation GO:0009953 125 0.023
response to wounding GO:0009611 116 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
anion transport GO:0006820 38 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
lipid storage GO:0019915 1 0.023
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
regulation of cell communication GO:0010646 232 0.022
amine metabolic process GO:0009308 2 0.021
lateral line system development GO:0048925 76 0.021
peptide metabolic process GO:0006518 1 0.021
organic substance biosynthetic process GO:1901576 289 0.021
actin cytoskeleton organization GO:0030036 63 0.021
multi organism process GO:0051704 134 0.021
negative regulation of mapk cascade GO:0043409 4 0.021
cellular component disassembly GO:0022411 1 0.021
positive regulation of cell communication GO:0010647 56 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
negative regulation of catalytic activity GO:0043086 21 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
protein localization to plasma membrane GO:0072659 1 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of transport GO:0051049 45 0.020
lipid catabolic process GO:0016042 4 0.020
posttranscriptional regulation of gene expression GO:0010608 14 0.020
negative regulation of developmental process GO:0051093 65 0.019
specification of organ identity GO:0010092 2 0.019
peptidyl threonine phosphorylation GO:0018107 1 0.019
cellular protein modification process GO:0006464 100 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
regulation of inflammatory response GO:0050727 2 0.019
cell motility GO:0048870 244 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
nucleic acid templated transcription GO:0097659 181 0.018
response to uv GO:0009411 3 0.018
rna metabolic process GO:0016070 219 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
response to other organism GO:0051707 97 0.018
multi organism reproductive process GO:0044703 36 0.018
peptidyl serine modification GO:0018209 2 0.018
nucleic acid metabolic process GO:0090304 244 0.018
protein complex biogenesis GO:0070271 30 0.018
cytoskeleton organization GO:0007010 96 0.018
response to lipid GO:0033993 60 0.018
regulation of signal transduction GO:0009966 225 0.018
epidermal cell differentiation GO:0009913 36 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.017
gtp catabolic process GO:0006184 2 0.017
adherens junction organization GO:0034332 4 0.017
digestive tract development GO:0048565 265 0.017
digestive system development GO:0055123 289 0.017
negative regulation of molecular function GO:0044092 23 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
phagocytosis engulfment GO:0006911 1 0.017
regulation of chromosome segregation GO:0051983 1 0.017
osteoclast development GO:0036035 1 0.017
cellular biosynthetic process GO:0044249 286 0.017
fatty acid biosynthetic process GO:0006633 4 0.016
homeostasis of number of cells GO:0048872 62 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
fatty acid transport GO:0015908 1 0.016
energy reserve metabolic process GO:0006112 2 0.016
hair cell differentiation GO:0035315 32 0.016
epidermis development GO:0008544 48 0.016
heterocycle metabolic process GO:0046483 290 0.016
protein metabolic process GO:0019538 183 0.016
Mouse Rat
cellular protein catabolic process GO:0044257 4 0.016
positive regulation of signaling GO:0023056 56 0.016
cellular response to lipid GO:0071396 39 0.016
intracellular signal transduction GO:0035556 85 0.015
cell differentiation involved in kidney development GO:0061005 13 0.015
cellular response to stress GO:0033554 62 0.015
cellular localization GO:0051641 97 0.015
cellular protein metabolic process GO:0044267 129 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
cytokinetic process GO:0032506 2 0.015
regulation of signaling GO:0023051 235 0.015
cellular response to starvation GO:0009267 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
regulation of primary metabolic process GO:0080090 311 0.015
response to glucocorticoid GO:0051384 1 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.014
response to biotic stimulus GO:0009607 97 0.014
regulation of molecular function GO:0065009 70 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
cellular component assembly GO:0022607 170 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
heart jogging GO:0003146 40 0.014
macromolecule modification GO:0043412 111 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
establishment of localization in cell GO:0051649 77 0.014
gastrulation GO:0007369 208 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
phosphorus metabolic process GO:0006793 109 0.014
embryonic organ development GO:0048568 381 0.014
chemosensory behavior GO:0007635 1 0.014
liver development GO:0001889 96 0.014
collagen biosynthetic process GO:0032964 2 0.014
nuclear division GO:0000280 23 0.014
peptidyl serine phosphorylation GO:0018105 1 0.013
glycosyl compound metabolic process GO:1901657 11 0.013
homeostatic process GO:0042592 142 0.013
regulation of localization GO:0032879 104 0.013
meiotic chromosome segregation GO:0045132 3 0.013
cofactor metabolic process GO:0051186 15 0.013
regulation of proteolysis GO:0030162 24 0.013
b cell activation GO:0042113 2 0.013
lateral line development GO:0048882 66 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
cell substrate adhesion GO:0031589 4 0.013
centrosome cycle GO:0007098 1 0.013
protein complex disassembly GO:0043241 1 0.013
regulation of water loss via skin GO:0033561 1 0.013
heart field specification GO:0003128 1 0.013
leukocyte differentiation GO:0002521 25 0.013
regulation of glial cell differentiation GO:0045685 4 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of apoptotic process GO:0043065 29 0.012
cellular macromolecule localization GO:0070727 21 0.012
muscle structure development GO:0061061 196 0.012
negative regulation of secretion GO:0051048 2 0.012
nucleotide biosynthetic process GO:0009165 21 0.012
axon development GO:0061564 166 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of interferon beta production GO:0032648 1 0.012
meiotic cell cycle process GO:1903046 3 0.012
protein acylation GO:0043543 3 0.012
negative regulation of defense response GO:0031348 2 0.012
intracellular mrna localization GO:0008298 1 0.012
cellular response to external stimulus GO:0071496 2 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
biosynthetic process GO:0009058 294 0.011
lipid localization GO:0010876 11 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
negative regulation of metabolic process GO:0009892 86 0.011
regulation of metal ion transport GO:0010959 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of cell development GO:0010720 25 0.011
oocyte maturation GO:0001556 4 0.011
regulation of cell development GO:0060284 100 0.011
stem cell maintenance GO:0019827 4 0.011
autophagy GO:0006914 4 0.011
myeloid cell differentiation GO:0030099 86 0.011
response to abiotic stimulus GO:0009628 122 0.011
regulation of rac protein signal transduction GO:0035020 1 0.011
organism emergence from protective structure GO:0071684 4 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
negative regulation of mitosis GO:0045839 3 0.010
hemostasis GO:0007599 13 0.010
regulation of transcription dna templated GO:0006355 213 0.010
defense response to fungus GO:0050832 2 0.010
regulation of endopeptidase activity GO:0052548 23 0.010
cell growth GO:0016049 57 0.010
gland development GO:0048732 143 0.010
regeneration GO:0031099 91 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
regulation of reproductive process GO:2000241 4 0.010
regulation of gene expression GO:0010468 265 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
cellular protein localization GO:0034613 20 0.010
regulation of locomotion GO:0040012 55 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
regulation of defense response to virus by host GO:0050691 1 0.010
central nervous system development GO:0007417 387 0.010
positive regulation of cell substrate adhesion GO:0010811 1 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
generation of neurons GO:0048699 385 0.010
membrane organization GO:0061024 21 0.010

capns1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
nervous system disease DOID:863 0 0.020
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
integumentary system disease DOID:16 0 0.010