Danio rerio

17 known processes

pald

paladin

(Aliases: sb:cb559,cb942)

pald biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.305
regulation of metabolic process GO:0019222 359 0.186
modification dependent protein catabolic process GO:0019941 3 0.185
negative regulation of cellular process GO:0048523 283 0.112
signal transduction GO:0007165 455 0.105
neuroblast proliferation GO:0007405 2 0.105
nuclear migration GO:0007097 3 0.100
cell surface receptor signaling pathway GO:0007166 325 0.096
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.093
organic substance biosynthetic process GO:1901576 289 0.081
single organism metabolic process GO:0044710 217 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.077
gastrulation GO:0007369 208 0.073
cellular protein catabolic process GO:0044257 4 0.072
positive regulation of map kinase activity GO:0043406 3 0.069
ubiquitin dependent protein catabolic process GO:0006511 3 0.067
neuron differentiation GO:0030182 353 0.067
regulation of meiotic cell cycle GO:0051445 1 0.067
negative regulation of biological process GO:0048519 304 0.063
erk1 and erk2 cascade GO:0070371 4 0.062
modification dependent macromolecule catabolic process GO:0043632 3 0.062
meiotic nuclear division GO:0007126 4 0.061
cellular protein modification process GO:0006464 100 0.059
cellular amino acid metabolic process GO:0006520 7 0.059
stem cell proliferation GO:0072089 4 0.059
regulation of establishment of protein localization GO:0070201 4 0.052
cellular amine metabolic process GO:0044106 2 0.050
cell migration involved in gastrulation GO:0042074 79 0.050
regulation of protein transport GO:0051223 3 0.047
carboxylic acid metabolic process GO:0019752 22 0.047
regulation of developmental process GO:0050793 247 0.046
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.043
regulation of biological quality GO:0065008 263 0.042
establishment of localization GO:0051234 244 0.040
regulation of protein complex assembly GO:0043254 3 0.040
regulation of protein import into nucleus GO:0042306 2 0.039
cilium assembly GO:0042384 58 0.039
amine metabolic process GO:0009308 2 0.039
organic cyclic compound metabolic process GO:1901360 301 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
protein modification process GO:0036211 100 0.037
digestive system development GO:0055123 289 0.036
male meiosis GO:0007140 2 0.035
meiosis i GO:0007127 1 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.033
negative regulation of signaling GO:0023057 96 0.033
cellular macromolecule metabolic process GO:0044260 391 0.033
proteasomal protein catabolic process GO:0010498 2 0.032
wnt signaling pathway GO:0016055 80 0.032
cellular ketone metabolic process GO:0042180 11 0.031
long chain fatty acid metabolic process GO:0001676 1 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
macromolecule modification GO:0043412 111 0.029
biosynthetic process GO:0009058 294 0.028
heterocycle metabolic process GO:0046483 290 0.028
digestive tract morphogenesis GO:0048546 231 0.028
phagocytosis GO:0006909 3 0.027
digestive tract development GO:0048565 265 0.027
negative regulation of signal transduction GO:0009968 94 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.027
phosphorus metabolic process GO:0006793 109 0.027
regulation of protein ubiquitination GO:0031396 3 0.026
defense response to other organism GO:0098542 33 0.026
endosomal transport GO:0016197 2 0.026
meiotic cell cycle process GO:1903046 3 0.026
protein polymerization GO:0051258 4 0.026
regulation of signal transduction GO:0009966 225 0.026
cellular protein metabolic process GO:0044267 129 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
organic acid metabolic process GO:0006082 31 0.025
regulation of stem cell proliferation GO:0072091 2 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.024
rna 3 end processing GO:0031123 2 0.024
protein dephosphorylation GO:0006470 3 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
estrogen metabolic process GO:0008210 2 0.023
positive regulation of stress activated mapk cascade GO:0032874 3 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
oxoacid metabolic process GO:0043436 31 0.023
compound eye development GO:0048749 2 0.023
phosphate containing compound metabolic process GO:0006796 108 0.022
response to chemical GO:0042221 320 0.022
organelle assembly GO:0070925 110 0.022
regulation of cytokine production GO:0001817 3 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
multi organism process GO:0051704 134 0.022
cell projection assembly GO:0030031 64 0.022
vasculature development GO:0001944 278 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
cortical cytoskeleton organization GO:0030865 1 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
response to vitamin GO:0033273 3 0.022
positive regulation of stem cell proliferation GO:2000648 1 0.021
immune system development GO:0002520 191 0.021
radial glial cell differentiation GO:0060019 2 0.021
positive regulation of chromatin modification GO:1903310 1 0.021
nuclear transport GO:0051169 4 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.020
hemopoiesis GO:0030097 183 0.020
spindle assembly involved in meiosis GO:0090306 1 0.020
b cell activation GO:0042113 2 0.020
phosphorylation GO:0016310 69 0.020
cellular modified amino acid metabolic process GO:0006575 3 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
regulation of protein catabolic process GO:0042176 1 0.019
cytokinesis GO:0000910 3 0.019
regulation of protein polymerization GO:0032271 2 0.019
response to drug GO:0042493 3 0.019
generation of neurons GO:0048699 385 0.019
regulation of chromosome segregation GO:0051983 1 0.019
convergent extension involved in gastrulation GO:0060027 71 0.019
regulation of signaling GO:0023051 235 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.018
phagocytosis engulfment GO:0006911 1 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
regulation of intracellular signal transduction GO:1902531 57 0.018
actin filament polymerization GO:0030041 2 0.018
angiogenesis GO:0001525 158 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
nucleic acid metabolic process GO:0090304 244 0.018
cellular biosynthetic process GO:0044249 286 0.018
cellular component biogenesis GO:0044085 178 0.017
chemosensory behavior GO:0007635 1 0.017
positive regulation of cell substrate adhesion GO:0010811 1 0.017
nucleus localization GO:0051647 8 0.017
positive regulation of biological process GO:0048518 253 0.017
regulation of cell communication GO:0010646 232 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
regulation of protein targeting GO:1903533 2 0.017
single fertilization GO:0007338 3 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
nuclear import GO:0051170 3 0.017
blood vessel development GO:0001568 246 0.017
response to nutrient GO:0007584 3 0.016
regulation of jun kinase activity GO:0043506 3 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
head development GO:0060322 303 0.016
striated muscle cell development GO:0055002 108 0.016
somite development GO:0061053 96 0.016
maintenance of location GO:0051235 4 0.016
regulation of synapse organization GO:0050807 3 0.016
positive regulation of histone modification GO:0031058 1 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
adherens junction organization GO:0034332 4 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
cell cell recognition GO:0009988 1 0.015
central nervous system development GO:0007417 387 0.015
cell cycle process GO:0022402 53 0.015
peptidyl serine modification GO:0018209 2 0.015
dna templated transcription elongation GO:0006354 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
intracellular signal transduction GO:0035556 85 0.015
negative regulation of cell communication GO:0010648 96 0.015
locomotion GO:0040011 313 0.015
production of molecular mediator of immune response GO:0002440 2 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
multicellular organism growth GO:0035264 4 0.014
dna metabolic process GO:0006259 27 0.014
localization of cell GO:0051674 244 0.014
developmental growth GO:0048589 166 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
small molecule metabolic process GO:0044281 77 0.014
response to external stimulus GO:0009605 264 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of gene expression GO:0010468 265 0.014
negative regulation of collateral sprouting GO:0048671 2 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
androgen metabolic process GO:0008209 2 0.013
nuclear envelope organization GO:0006998 2 0.013
regulation of biosynthetic process GO:0009889 250 0.013
positive regulation of catabolic process GO:0009896 4 0.013
cell fate commitment GO:0045165 99 0.013
stem cell maintenance GO:0019827 4 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
sex determination GO:0007530 1 0.013
synaptic target recognition GO:0008039 1 0.013
protein metabolic process GO:0019538 183 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
embryonic hemopoiesis GO:0035162 53 0.013
regulation of receptor mediated endocytosis GO:0048259 4 0.013
muscle structure development GO:0061061 196 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
regulation of phosphorylation GO:0042325 26 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
branching morphogenesis of a nerve GO:0048755 4 0.012
lateral inhibition GO:0046331 1 0.012
atp catabolic process GO:0006200 4 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
positive regulation of transport GO:0051050 2 0.012
regionalization GO:0003002 274 0.012
somatic muscle development GO:0007525 4 0.012
membrane invagination GO:0010324 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
cilium organization GO:0044782 71 0.012
lipid storage GO:0019915 1 0.012
peptidyl tyrosine dephosphorylation GO:0035335 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
negative regulation of ras protein signal transduction GO:0046580 1 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of synapse assembly GO:0051963 3 0.012
cellular component disassembly GO:0022411 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
spermatid development GO:0007286 2 0.012
positive regulation of phospholipase c activity GO:0010863 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
behavior GO:0007610 74 0.012
stem cell division GO:0017145 1 0.012
gene expression GO:0010467 252 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
protein import GO:0017038 3 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
protein heterooligomerization GO:0051291 1 0.011
fertilization GO:0009566 3 0.011
cell cycle GO:0007049 93 0.011
protein localization to nucleus GO:0034504 3 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
determination of left right symmetry GO:0007368 179 0.011
dicarboxylic acid transport GO:0006835 1 0.011
cytokinetic process GO:0032506 2 0.011
regulation of mitotic cell cycle embryonic GO:0009794 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
neural precursor cell proliferation GO:0061351 20 0.011
convergent extension GO:0060026 118 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
spindle assembly GO:0051225 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
negative regulation of kinase activity GO:0033673 4 0.011
response to uv GO:0009411 3 0.011
regeneration GO:0031099 91 0.011
negative chemotaxis GO:0050919 1 0.011
tube morphogenesis GO:0035239 349 0.010
single organism localization GO:1902578 225 0.010
growth GO:0040007 174 0.010
cytoskeleton organization GO:0007010 96 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
protein phosphorylation GO:0006468 47 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
mitotic cell cycle GO:0000278 64 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
cell morphogenesis GO:0000902 289 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010

pald disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.012
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010