Danio rerio

0 known processes

mul1b

mitochondrial E3 ubiquitin ligase 1b

(Aliases: im:7146383,zgc:165594,MGC165594)

mul1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.081
aging GO:0007568 2 0.053
maintenance of location GO:0051235 4 0.038
multicellular organism growth GO:0035264 4 0.035
meiotic nuclear division GO:0007126 4 0.035
cellular protein catabolic process GO:0044257 4 0.034
positive regulation of transport GO:0051050 2 0.034
lipid storage GO:0019915 1 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
nuclear transport GO:0051169 4 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
positive regulation of catabolic process GO:0009896 4 0.029
regulation of cytokine production GO:0001817 3 0.029
phagocytosis GO:0006909 3 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
proteasomal protein catabolic process GO:0010498 2 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
regulation of mrna processing GO:0050684 3 0.028
protein acetylation GO:0006473 2 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
heterocycle metabolic process GO:0046483 290 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
stem cell maintenance GO:0019827 4 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
amine metabolic process GO:0009308 2 0.027
signal transduction GO:0007165 455 0.027
regulation of protein transport GO:0051223 3 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
protein localization to nucleus GO:0034504 3 0.025
cellular amine metabolic process GO:0044106 2 0.025
regulation of protein catabolic process GO:0042176 1 0.025
cellular respiration GO:0045333 3 0.025
mitochondrion organization GO:0007005 4 0.025
autophagy GO:0006914 4 0.025
biosynthetic process GO:0009058 294 0.025
modification dependent protein catabolic process GO:0019941 3 0.024
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
regulation of protein complex assembly GO:0043254 3 0.024
protein import GO:0017038 3 0.024
peptidyl lysine acetylation GO:0018394 2 0.024
internal protein amino acid acetylation GO:0006475 2 0.024
regulation of mrna splicing via spliceosome GO:0048024 3 0.024
cellular response to external stimulus GO:0071496 2 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
response to drug GO:0042493 3 0.023
rna localization GO:0006403 4 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
gtp metabolic process GO:0046039 4 0.023
meiotic cell cycle process GO:1903046 3 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
protein acylation GO:0043543 3 0.022
cellular biosynthetic process GO:0044249 286 0.022
single organism nuclear import GO:1902593 3 0.022
internal peptidyl lysine acetylation GO:0018393 2 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
rna metabolic process GO:0016070 219 0.022
regulation of protein ubiquitination GO:0031396 3 0.022
single organism metabolic process GO:0044710 217 0.022
nucleic acid metabolic process GO:0090304 244 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
organic substance biosynthetic process GO:1901576 289 0.021
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
regulation of cell shape GO:0008360 1 0.021
cellular ketone metabolic process GO:0042180 11 0.020
endosomal transport GO:0016197 2 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
gene expression GO:0010467 252 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
positive regulation of cell cycle GO:0045787 3 0.020
gtp catabolic process GO:0006184 2 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
transcription dna templated GO:0006351 181 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
cognition GO:0050890 1 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
establishment of localization GO:0051234 244 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
regulation of metabolic process GO:0019222 359 0.019
locomotor rhythm GO:0045475 3 0.019
regulation of binding GO:0051098 3 0.019
golgi vesicle transport GO:0048193 3 0.019
single organism membrane fusion GO:0044801 2 0.019
nuclear import GO:0051170 3 0.019
membrane fusion GO:0061025 2 0.019
immune system process GO:0002376 241 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of gene expression GO:0010468 265 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
cellular response to nutrient levels GO:0031669 2 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
regulation of primary metabolic process GO:0080090 311 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
regulation of cell activation GO:0050865 1 0.018
response to uv GO:0009411 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
positive regulation of cytokine production GO:0001819 2 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
cellular response to starvation GO:0009267 1 0.018
leukocyte proliferation GO:0070661 1 0.018
cytokinesis GO:0000910 3 0.018
rna biosynthetic process GO:0032774 181 0.018
meiotic chromosome segregation GO:0045132 3 0.018
protein polymerization GO:0051258 4 0.018
organelle fusion GO:0048284 3 0.018
cellular component movement GO:0006928 335 0.018
negative regulation of biological process GO:0048519 304 0.018
stem cell proliferation GO:0072089 4 0.018
atp catabolic process GO:0006200 4 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of biological quality GO:0065008 263 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cellular response to radiation GO:0071478 4 0.017
protein complex disassembly GO:0043241 1 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of rna metabolic process GO:0051252 224 0.017
organic acid metabolic process GO:0006082 31 0.017
positive regulation of translation GO:0045727 1 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
tissue remodeling GO:0048771 4 0.017
positive regulation of cell activation GO:0050867 1 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
macromolecular complex disassembly GO:0032984 1 0.017
nuclear export GO:0051168 1 0.017
protein secretion GO:0009306 1 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
immune system development GO:0002520 191 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
protein localization to plasma membrane GO:0072659 1 0.016
organelle organization GO:0006996 227 0.016
central nervous system development GO:0007417 387 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
response to chemical GO:0042221 320 0.016
centrosome organization GO:0051297 1 0.016
cell matrix adhesion GO:0007160 4 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of catabolic process GO:0009895 3 0.016
protein polyubiquitination GO:0000209 4 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
double strand break repair GO:0006302 3 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
b cell activation GO:0042113 2 0.016
female gonad development GO:0008585 4 0.016
mononuclear cell proliferation GO:0032943 1 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
female sex differentiation GO:0046660 4 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
small molecule metabolic process GO:0044281 77 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of synapse organization GO:0050807 3 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
nucleic acid templated transcription GO:0097659 181 0.015
transport GO:0006810 220 0.015
cellular component biogenesis GO:0044085 178 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
developmental programmed cell death GO:0010623 4 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
nucleic acid transport GO:0050657 2 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
sensory organ development GO:0007423 393 0.015
protein dephosphorylation GO:0006470 3 0.015
response to stress GO:0006950 263 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
response to topologically incorrect protein GO:0035966 2 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
protein metabolic process GO:0019538 183 0.015
phagocytosis engulfment GO:0006911 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of gtpase activity GO:0043087 2 0.015
single organism transport GO:0044765 206 0.015
regulation of organelle assembly GO:1902115 4 0.015
regulation of signal transduction GO:0009966 225 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of response to stimulus GO:0048583 269 0.015
spermatid development GO:0007286 2 0.015
regulation of inflammatory response GO:0050727 2 0.015
compound eye development GO:0048749 2 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
stem cell division GO:0017145 1 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
response to external stimulus GO:0009605 264 0.015
erk1 and erk2 cascade GO:0070371 4 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
membrane invagination GO:0010324 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
single organism organelle organization GO:1902589 199 0.014
peptide transport GO:0015833 1 0.014
peptidyl serine modification GO:0018209 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
locomotion GO:0040011 313 0.014
cell migration GO:0016477 237 0.014
rna transport GO:0050658 2 0.014
dna templated transcription elongation GO:0006354 3 0.014
lymphocyte proliferation GO:0046651 1 0.014
actin filament polymerization GO:0030041 2 0.014
hemopoiesis GO:0030097 183 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
eye development GO:0001654 277 0.014
generation of neurons GO:0048699 385 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of cell communication GO:0010646 232 0.014
neuroblast proliferation GO:0007405 2 0.014
response to monosaccharide GO:0034284 3 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
somatic stem cell maintenance GO:0035019 1 0.014
positive regulation of immune effector process GO:0002699 3 0.014
system process GO:0003008 185 0.014
regulation of signaling GO:0023051 235 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of transcription dna templated GO:0006355 213 0.013
cellular component assembly GO:0022607 170 0.013
exocytosis GO:0006887 1 0.013
digestive system development GO:0055123 289 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
establishment of rna localization GO:0051236 3 0.013
tube morphogenesis GO:0035239 349 0.013
cellular component morphogenesis GO:0032989 336 0.013
single organism localization GO:1902578 225 0.013
regulation of circadian rhythm GO:0042752 4 0.013
chemosensory behavior GO:0007635 1 0.013
meiosis i GO:0007127 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
spindle assembly GO:0051225 2 0.013
carbohydrate homeostasis GO:0033500 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
negative regulation of cytokine production GO:0001818 1 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
spermatid differentiation GO:0048515 2 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
response to hexose GO:0009746 3 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
cellular response to light stimulus GO:0071482 4 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
cell substrate adhesion GO:0031589 4 0.013
glucose homeostasis GO:0042593 1 0.013
regulation of blood pressure GO:0008217 1 0.013
negative regulation of nuclear division GO:0051784 3 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
cell part morphogenesis GO:0032990 246 0.013
intracellular signal transduction GO:0035556 85 0.013
cell morphogenesis GO:0000902 289 0.013
cellular amide metabolic process GO:0043603 4 0.013
positive regulation of gtpase activity GO:0043547 1 0.012
response to alkaloid GO:0043279 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
lipid homeostasis GO:0055088 3 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
regulation of developmental process GO:0050793 247 0.012
regulation of autophagy GO:0010506 3 0.012
negative regulation of kinase activity GO:0033673 4 0.012
brain development GO:0007420 293 0.012
neuron differentiation GO:0030182 353 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
macromolecule modification GO:0043412 111 0.012
intracellular mrna localization GO:0008298 1 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
multi organism cellular process GO:0044764 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
rna export from nucleus GO:0006405 1 0.012
lateral inhibition GO:0046331 1 0.012
hormone secretion GO:0046879 2 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
regulation of protein polymerization GO:0032271 2 0.012
centrosome cycle GO:0007098 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
response to carbohydrate GO:0009743 3 0.012
fertilization GO:0009566 3 0.012
vasculature development GO:0001944 278 0.012
antimicrobial humoral response GO:0019730 2 0.012
somatic muscle development GO:0007525 4 0.012
post embryonic organ development GO:0048569 4 0.012
head development GO:0060322 303 0.012
regulation of transporter activity GO:0032409 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
localization of cell GO:0051674 244 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
growth GO:0040007 174 0.012
regulation of metal ion transport GO:0010959 4 0.012
lamellipodium assembly GO:0030032 1 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.011
positive regulation of cellular process GO:0048522 201 0.011
translational initiation GO:0006413 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
homeostatic process GO:0042592 142 0.011
nucleobase containing compound transport GO:0015931 2 0.011
cell motility GO:0048870 244 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
mitochondrial transport GO:0006839 2 0.011
cell substrate junction assembly GO:0007044 2 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
apoptotic process involved in development GO:1902742 2 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
regulation of organ growth GO:0046620 3 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
embryonic organ development GO:0048568 381 0.011
vacuolar transport GO:0007034 2 0.011
sequestering of metal ion GO:0051238 3 0.011
response to unfolded protein GO:0006986 2 0.011
response to hydrogen peroxide GO:0042542 3 0.011
specification of symmetry GO:0009799 204 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
viral process GO:0016032 1 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
regionalization GO:0003002 274 0.011
protein homooligomerization GO:0051260 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
digestive tract morphogenesis GO:0048546 231 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
lamellipodium organization GO:0097581 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
primary neural tube formation GO:0014020 1 0.011
activation of mapk activity GO:0000187 3 0.011
tube closure GO:0060606 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
ameboidal type cell migration GO:0001667 143 0.011
digestive tract development GO:0048565 265 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.010
heart development GO:0007507 313 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
microtubule organizing center organization GO:0031023 1 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
mitotic cytokinesis GO:0000281 3 0.010
protein modification process GO:0036211 100 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
negative regulation of defense response GO:0031348 2 0.010
cellular protein modification process GO:0006464 100 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
hormone transport GO:0009914 2 0.010
er nucleus signaling pathway GO:0006984 2 0.010
muscle structure development GO:0061061 196 0.010
rna modification GO:0009451 2 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
response to abiotic stimulus GO:0009628 122 0.010
mitotic cell cycle embryonic GO:0045448 2 0.010
rna 3 end processing GO:0031123 2 0.010
gastrulation GO:0007369 208 0.010
adult behavior GO:0030534 2 0.010
positive regulation of multi organism process GO:0043902 3 0.010
response to nutrient GO:0007584 3 0.010
b cell differentiation GO:0030183 1 0.010
cellular response to organic substance GO:0071310 105 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
mrna transport GO:0051028 2 0.010

mul1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of metabolism DOID:0014667 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010