Danio rerio

51 known processes

rac2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

(Aliases: zgc:86686)

rac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
t cell activation GO:0042110 6 0.241
immune system process GO:0002376 241 0.194
cell projection organization GO:0030030 284 0.161
Human Mouse Worm Fly
tube morphogenesis GO:0035239 349 0.146
Zebrafish Fly
larval development GO:0002164 2 0.145
Worm
regulation of synapse assembly GO:0051963 3 0.120
Fly
neuron development GO:0048666 262 0.120
Worm Fly
neuron differentiation GO:0030182 353 0.105
Worm Fly
cell projection morphogenesis GO:0048858 244 0.105
Worm Fly
regulation of synapse organization GO:0050807 3 0.096
Fly
cell motility GO:0048870 244 0.096
regulation of cell shape GO:0008360 1 0.095
Fly
regulation of protein complex assembly GO:0043254 3 0.084
positive regulation of cellular component biogenesis GO:0044089 3 0.079
Human Mouse Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.074
actin polymerization or depolymerization GO:0008154 2 0.073
regulation of protein polymerization GO:0032271 2 0.071
regulation of multicellular organismal development GO:2000026 223 0.071
Worm Fly
regulation of establishment of protein localization GO:0070201 4 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.067
regulation of cell activation GO:0050865 1 0.067
response to drug GO:0042493 3 0.067
localization of cell GO:0051674 244 0.066
amine metabolic process GO:0009308 2 0.065
organic acid metabolic process GO:0006082 31 0.064
oxoacid metabolic process GO:0043436 31 0.061
response to chemical GO:0042221 320 0.060
Human Mouse Worm Fly
protein polymerization GO:0051258 4 0.059
organic cyclic compound metabolic process GO:1901360 301 0.058
Mouse Worm Fly
phagocytosis GO:0006909 3 0.057
Worm Fly
cellular response to external stimulus GO:0071496 2 0.056
phosphate containing compound metabolic process GO:0006796 108 0.056
Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.056
Mouse Worm Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.055
eye development GO:0001654 277 0.054
Fly
carboxylic acid metabolic process GO:0019752 22 0.053
regulation of multicellular organism growth GO:0040014 4 0.053
cell morphogenesis involved in differentiation GO:0000904 195 0.052
Worm Fly
neuron projection morphogenesis GO:0048812 161 0.052
Worm Fly
regionalization GO:0003002 274 0.051
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.051
axon development GO:0061564 166 0.051
Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.050
Worm Fly
regulation of protein transport GO:0051223 3 0.050
response to external stimulus GO:0009605 264 0.048
Human Zebrafish Mouse Worm Fly
cellular amine metabolic process GO:0044106 2 0.048
nitrogen compound metabolic process GO:0006807 319 0.048
Mouse Worm Fly
cellular amino acid metabolic process GO:0006520 7 0.047
defense response GO:0006952 47 0.046
Fly
cognition GO:0050890 1 0.045
generation of neurons GO:0048699 385 0.045
Worm Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.045
positive regulation of cellular process GO:0048522 201 0.045
organonitrogen compound metabolic process GO:1901564 74 0.044
Mouse Worm Fly
regulation of cellular amine metabolic process GO:0033238 0 0.043
locomotion GO:0040011 313 0.043
positive regulation of protein complex assembly GO:0031334 2 0.043
nucleocytoplasmic transport GO:0006913 4 0.043
maintenance of location GO:0051235 4 0.043
Fly
cellular ketone metabolic process GO:0042180 11 0.042
positive regulation of protein polymerization GO:0032273 2 0.042
positive regulation of catabolic process GO:0009896 4 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
Mouse Worm Fly
embryonic organ development GO:0048568 381 0.040
Fly
keratinocyte differentiation GO:0030216 0 0.040
heterocycle metabolic process GO:0046483 290 0.040
Mouse Worm Fly
regulation of cell projection assembly GO:0060491 4 0.040
Human Mouse Fly
specification of symmetry GO:0009799 204 0.038
Fly
cell morphogenesis GO:0000902 289 0.038
Worm Fly
dicarboxylic acid transport GO:0006835 1 0.038
actin filament polymerization GO:0030041 2 0.037
cell migration GO:0016477 237 0.037
axon guidance GO:0007411 86 0.037
Worm Fly
digestive tract development GO:0048565 265 0.037
Zebrafish Fly
retina development in camera type eye GO:0060041 146 0.037
regulation of cytoplasmic transport GO:1903649 4 0.037
cell part morphogenesis GO:0032990 246 0.037
Worm Fly
adherens junction organization GO:0034332 4 0.036
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
multicellular organism growth GO:0035264 4 0.036
camera type eye development GO:0043010 222 0.035
protein metabolic process GO:0019538 183 0.035
Fly
brain development GO:0007420 293 0.034
autophagy GO:0006914 4 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
endosomal transport GO:0016197 2 0.034
protein secretion GO:0009306 1 0.034
digestive system development GO:0055123 289 0.034
Zebrafish Fly
cellular component assembly GO:0022607 170 0.033
Human Mouse Fly
head development GO:0060322 303 0.033
epithelial cell differentiation GO:0030855 116 0.033
Fly
aging GO:0007568 2 0.033
gene expression GO:0010467 252 0.033
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.033
regulation of cellular metabolic process GO:0031323 320 0.032
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.031
Fly
regulation of binding GO:0051098 3 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
Worm Fly
positive regulation of inflammatory response GO:0050729 1 0.031
lipid catabolic process GO:0016042 4 0.031
negative regulation of protein kinase activity GO:0006469 4 0.030
regulation of protein import into nucleus GO:0042306 2 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.029
regulation of intracellular protein transport GO:0033157 3 0.029
positive regulation of transport GO:0051050 2 0.029
gland development GO:0048732 143 0.029
Fly
morphogenesis of an epithelium GO:0002009 333 0.028
Fly
single organism membrane fusion GO:0044801 2 0.028
regulation of inflammatory response GO:0050727 2 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
Mouse Worm Fly
single organism nuclear import GO:1902593 3 0.028
single organism metabolic process GO:0044710 217 0.027
Human Mouse Worm Fly
cytokinesis GO:0000910 3 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
protein import GO:0017038 3 0.027
immune system development GO:0002520 191 0.027
Fly
nuclear transport GO:0051169 4 0.027
rna metabolic process GO:0016070 219 0.027
negative regulation of cellular process GO:0048523 283 0.027
Fly
chemotaxis GO:0006935 104 0.027
Human Mouse Worm Fly
heart development GO:0007507 313 0.027
positive regulation of apoptotic signaling pathway GO:2001235 1 0.027
lymph vessel development GO:0001945 27 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
Mouse Worm Fly
digestive tract morphogenesis GO:0048546 231 0.026
Zebrafish Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
regulation of response to stimulus GO:0048583 269 0.026
Human Mouse Fly
regulation of metal ion transport GO:0010959 4 0.026
multicellular organismal metabolic process GO:0044236 2 0.026
single organism transport GO:0044765 206 0.025
Worm Fly
central nervous system development GO:0007417 387 0.025
Fly
single organism organelle organization GO:1902589 199 0.025
Human Mouse Rat Fly
regulation of sodium ion transport GO:0002028 2 0.025
hemopoiesis GO:0030097 183 0.025
Fly
sequestering of calcium ion GO:0051208 3 0.025
cellular component movement GO:0006928 335 0.025
positive regulation of cytoskeleton organization GO:0051495 3 0.025
cell projection assembly GO:0030031 64 0.025
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.025
cellular component morphogenesis GO:0032989 336 0.024
Worm Fly
determination of left right symmetry GO:0007368 179 0.024
Fly
organelle fusion GO:0048284 3 0.024
negative regulation of defense response GO:0031348 2 0.024
response to transition metal nanoparticle GO:1990267 28 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
adult behavior GO:0030534 2 0.024
collagen metabolic process GO:0032963 2 0.024
gastrulation GO:0007369 208 0.024
Zebrafish Fly
heart contraction GO:0060047 71 0.023
regulation of endopeptidase activity GO:0052548 23 0.023
cellular response to starvation GO:0009267 1 0.023
amino acid transport GO:0006865 2 0.023
positive regulation of metabolic process GO:0009893 108 0.023
Fly
aromatic compound biosynthetic process GO:0019438 217 0.023
regulation of protein targeting GO:1903533 2 0.023
blood circulation GO:0008015 87 0.023
calcium ion transport into cytosol GO:0060402 3 0.023
myeloid leukocyte migration GO:0097529 12 0.023
Human Mouse
positive regulation of cell activation GO:0050867 1 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
axonogenesis GO:0007409 152 0.022
Worm Fly
cellular response to lipopolysaccharide GO:0071222 3 0.022
peptide transport GO:0015833 1 0.022
definitive hemopoiesis GO:0060216 18 0.022
negative regulation of kinase activity GO:0033673 4 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
regulation of peptidase activity GO:0052547 23 0.022
protein localization to nucleus GO:0034504 3 0.022
leukocyte proliferation GO:0070661 1 0.022
convergent extension involved in gastrulation GO:0060027 71 0.022
cell substrate adhesion GO:0031589 4 0.022
Human
protein targeting to nucleus GO:0044744 3 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
response to wounding GO:0009611 116 0.022
regulation of metabolic process GO:0019222 359 0.021
Human Fly
membrane fusion GO:0061025 2 0.021
negative regulation of synapse assembly GO:0051964 2 0.021
mitochondrion organization GO:0007005 4 0.021
regulation of filopodium assembly GO:0051489 2 0.021
Fly
small molecule catabolic process GO:0044282 3 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
response to amino acid GO:0043200 2 0.021
response to other organism GO:0051707 97 0.021
Zebrafish Fly
mononuclear cell proliferation GO:0032943 1 0.021
lipid storage GO:0019915 1 0.021
Fly
cellular response to organic substance GO:0071310 105 0.021
response to stress GO:0006950 263 0.020
growth GO:0040007 174 0.020
Worm Fly
circulatory system process GO:0003013 87 0.020
positive regulation of biological process GO:0048518 253 0.020
organelle assembly GO:0070925 110 0.020
lymphocyte proliferation GO:0046651 1 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
muscle structure development GO:0061061 196 0.020
Fly
defense response to fungus GO:0050832 2 0.019
single organism localization GO:1902578 225 0.019
Worm Fly
homeostasis of number of cells GO:0048872 62 0.019
epithelial cell morphogenesis GO:0003382 2 0.019
negative regulation of cytoplasmic transport GO:1903650 2 0.019
muscle cell differentiation GO:0042692 139 0.019
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.019
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.019
determination of bilateral symmetry GO:0009855 204 0.019
Fly
cellular modified amino acid metabolic process GO:0006575 3 0.019
negative regulation of protein transport GO:0051224 3 0.019
response to organic substance GO:0010033 153 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
nuclear import GO:0051170 3 0.019
tyrosine phosphorylation of stat protein GO:0007260 1 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
lymphocyte activation GO:0046649 10 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.018
meiotic cell cycle process GO:1903046 3 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
Fly
peptidyl serine modification GO:0018209 2 0.018
negative regulation of cytokine production GO:0001818 1 0.018
protein import into nucleus GO:0006606 3 0.017
post embryonic organ development GO:0048569 4 0.017
Worm Fly
sensory perception of pain GO:0019233 1 0.017
segmentation GO:0035282 97 0.017
Fly
response to ketone GO:1901654 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
histone h3 k4 methylation GO:0051568 2 0.017
protein modification process GO:0036211 100 0.017
Fly
cell activation GO:0001775 16 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
gtp catabolic process GO:0006184 2 0.017
Mouse Worm Fly
rna localization GO:0006403 4 0.017
Fly
spermatid differentiation GO:0048515 2 0.017
heart process GO:0003015 71 0.017
actin filament based movement GO:0030048 1 0.017
regulation of cytokine production GO:0001817 3 0.017
response to glucocorticoid GO:0051384 1 0.017
positive regulation of response to stimulus GO:0048584 80 0.016
Human Mouse Fly
response to external biotic stimulus GO:0043207 97 0.016
Zebrafish Fly
protein localization to plasma membrane GO:0072659 1 0.016
transport GO:0006810 220 0.016
Worm Fly
alcohol biosynthetic process GO:0046165 2 0.016
regulation of jak stat cascade GO:0046425 3 0.016
negative regulation of biological process GO:0048519 304 0.016
Fly
negative regulation of catabolic process GO:0009895 3 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
muscle attachment GO:0016203 9 0.016
Fly
leukocyte activation GO:0045321 12 0.016
phosphorus metabolic process GO:0006793 109 0.016
Mouse Worm Fly
b cell activation GO:0042113 2 0.016
anterior posterior pattern specification GO:0009952 152 0.016
Fly
lipid metabolic process GO:0006629 52 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
ion transport GO:0006811 114 0.016
heart looping GO:0001947 94 0.016
regulation of tube size GO:0035150 2 0.016
system process GO:0003008 185 0.016
Fly
positive regulation of cell adhesion GO:0045785 1 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
Mouse Worm Fly
macromolecule modification GO:0043412 111 0.016
Fly
response to inorganic substance GO:0010035 38 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
response to alkaloid GO:0043279 2 0.016
response to metal ion GO:0010038 34 0.016
regulation of programmed cell death GO:0043067 101 0.016
synaptic transmission cholinergic GO:0007271 4 0.015
cellular response to hypoxia GO:0071456 1 0.015
embryonic heart tube development GO:0035050 133 0.015
regulation of gene expression GO:0010468 265 0.015
cytosolic calcium ion transport GO:0060401 3 0.015
neuroblast proliferation GO:0007405 2 0.015
multicellular organismal macromolecule metabolic process GO:0044259 2 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
positive regulation of programmed cell death GO:0043068 29 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
programmed cell death GO:0012501 119 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
regulation of sequestering of calcium ion GO:0051282 4 0.015
muscle fiber development GO:0048747 52 0.015
Fly
regulation of calcium ion transport GO:0051924 2 0.015
negative regulation of signaling GO:0023057 96 0.015
regulation of nervous system development GO:0051960 90 0.015
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
muscle organ development GO:0007517 101 0.015
Fly
macromolecular complex disassembly GO:0032984 1 0.015
regulation of developmental process GO:0050793 247 0.015
Worm Fly
negative regulation of mapk cascade GO:0043409 4 0.015
fatty acid transport GO:0015908 1 0.015
regulation of signaling GO:0023051 235 0.015
gtp metabolic process GO:0046039 4 0.015
Mouse Worm Fly
regulation of autophagy GO:0010506 3 0.015
muscle cell development GO:0055001 115 0.015
Fly
chordate embryonic development GO:0043009 271 0.015
positive regulation of cell cycle GO:0045787 3 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
Mouse Worm Fly
phagocytosis engulfment GO:0006911 1 0.014
Worm
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cellular protein catabolic process GO:0044257 4 0.014
cellular component biogenesis GO:0044085 178 0.014
Human Mouse Fly
response to biotic stimulus GO:0009607 97 0.014
Zebrafish Fly
neutrophil migration GO:1990266 10 0.014
Human Mouse
monoamine transport GO:0015844 1 0.014
protein complex disassembly GO:0043241 1 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of blood vessel size GO:0050880 2 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
response to nutrient GO:0007584 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
macroautophagy GO:0016236 1 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
intracellular signal transduction GO:0035556 85 0.014
Worm Fly
developmental growth GO:0048589 166 0.014
Worm Fly
signal transduction GO:0007165 455 0.014
Mouse Worm Fly
sequestering of metal ion GO:0051238 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
negative regulation of secretion GO:0051048 2 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
positive regulation of cell death GO:0010942 29 0.014
regulation of transporter activity GO:0032409 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
single organism biosynthetic process GO:0044711 71 0.014
cellular response to oxygen levels GO:0071453 1 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
regulation of apoptotic process GO:0042981 98 0.013
regeneration GO:0031099 91 0.013
Worm
peptidyl serine phosphorylation GO:0018105 1 0.013
positive regulation of secretion GO:0051047 1 0.013
taxis GO:0042330 109 0.013
Human Mouse Worm Fly
muscle tissue development GO:0060537 110 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of cysteine type endopeptidase activity GO:2000116 21 0.013
glucose homeostasis GO:0042593 1 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.013
endocrine process GO:0050886 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
angiogenesis GO:0001525 158 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
epidermal cell differentiation GO:0009913 36 0.013
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
cellular biosynthetic process GO:0044249 286 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
cell matrix adhesion GO:0007160 4 0.013
hormone secretion GO:0046879 2 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
regulation of protein binding GO:0043393 3 0.013
regulation of rna biosynthetic process GO:2001141 213 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
positive regulation of histone modification GO:0031058 1 0.012
negative regulation of cell communication GO:0010648 96 0.012
neutrophil chemotaxis GO:0030593 10 0.012
Human Mouse
peptidyl lysine acetylation GO:0018394 2 0.012
membrane invagination GO:0010324 1 0.012
Worm
striated muscle tissue development GO:0014706 110 0.012
protein dephosphorylation GO:0006470 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
cellular component disassembly GO:0022411 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Human Mouse
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.012
skeletal muscle organ development GO:0060538 78 0.012
Fly
organelle organization GO:0006996 227 0.012
Human Mouse Rat Fly
regulation of organ growth GO:0046620 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
zymogen activation GO:0031638 3 0.012
epidermis development GO:0008544 48 0.012
Fly
cytokinetic process GO:0032506 2 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of response to external stimulus GO:0032101 31 0.012
Human Mouse
meiotic nuclear division GO:0007126 4 0.012
compound eye development GO:0048749 2 0.012
Fly
ameboidal type cell migration GO:0001667 143 0.012
Zebrafish Fly
regulation of nucleotide catabolic process GO:0030811 2 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
myotube differentiation GO:0014902 45 0.012
Fly
cell death GO:0008219 121 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
Fly
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
positive regulation of cytokine production GO:0001819 2 0.012
water homeostasis GO:0030104 4 0.012
protein acetylation GO:0006473 2 0.012
camera type eye morphogenesis GO:0048593 108 0.011
regulation of cell death GO:0010941 103 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of dendrite development GO:0050773 3 0.011
Fly
positive regulation of cell division GO:0051781 2 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
Fly
regulation of protein kinase b signaling GO:0051896 8 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
cellular extravasation GO:0045123 1 0.011
somatic muscle development GO:0007525 4 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
b cell differentiation GO:0030183 1 0.011
protein acylation GO:0043543 3 0.011
regulation of cell differentiation GO:0045595 142 0.011
Fly
b cell mediated immunity GO:0019724 3 0.011
response to endogenous stimulus GO:0009719 83 0.011
regulation of biological quality GO:0065008 263 0.011
sleep GO:0030431 1 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
Mouse
phosphorylation GO:0016310 69 0.011
Fly
regulation of reproductive process GO:2000241 4 0.011
eye morphogenesis GO:0048592 144 0.011
Fly
establishment of localization GO:0051234 244 0.011
Worm Fly
actin mediated cell contraction GO:0070252 1 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
l amino acid transport GO:0015807 1 0.011
sensory perception of smell GO:0007608 2 0.011
vasculature development GO:0001944 278 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
convergent extension GO:0060026 118 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
protein localization GO:0008104 40 0.011
Fly
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
calcium mediated signaling GO:0019722 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
stem cell proliferation GO:0072089 4 0.011
rna 3 end processing GO:0031123 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
multi organism process GO:0051704 134 0.011
Zebrafish Fly
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of cellular component organization GO:0051128 86 0.011
Human Mouse Worm Fly
regulation of blood pressure GO:0008217 1 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
protein complex localization GO:0031503 1 0.010
cellular protein metabolic process GO:0044267 129 0.010
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of cellular component size GO:0032535 30 0.010
positive regulation of blood circulation GO:1903524 2 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
striated muscle cell differentiation GO:0051146 129 0.010
Fly
regulation of circadian rhythm GO:0042752 4 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
response to corticosteroid GO:0031960 1 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
Fly
death GO:0016265 121 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
lymphocyte homeostasis GO:0002260 1 0.010
transmembrane transport GO:0055085 120 0.010

rac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.011
immune system disease DOID:2914 0 0.011